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饲料研究 2010年第2期33卷 73-74页

作者： keith c.behnke 程宗佳(摘译) 美国大豆协会国际项目北京办事处不详

挤压技术已出现近一个世纪，此技术始于橡胶工业生产，如：软管和胶带。依靠成批挤压的理念，挤压很早就应用在面条生产上。20世纪40年代，连续挤压在食物上首次应用，生产膨化谷物、玉米粉或粗面粉的小吃和粗面面条。

关键词：挤压设备设计工业生产挤压技术连续挤压玉米粉面条应用

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里程焦虑未解决美国人购买电动汽车意愿下降

商业周刊（中文版） 2024年第3期 50-51页

作者： keith Naughton 融汐(译) 不详

高昂的价格、高昂的融资利率以及对续航里程的担忧,将导致2024年美国电动汽车的普及放缓。当黛比·梅滕雷特(Debbie Mettenleiter)的旧现代汽车在行驶了20万英里后需要更换时,她决定加人电动汽车的行列。毕竟,特斯拉似乎出现在她居住的... 详细信息

高昂的价格、高昂的融资利率以及对续航里程的担忧,将导致2024年美国电动汽车的普及放缓。当黛比·梅滕雷特(Debbie Mettenleiter)的旧现代汽车在行驶了20万英里后需要更换时,她决定加人电动汽车的行列。毕竟,特斯拉似乎出现在她居住的圣地亚哥的每个红绿灯路口。甚至连她的女儿也有一辆。于是她付了250美元订金,准备买一辆特斯拉Model Y。

关键词：电动汽车续航里程红绿灯特斯拉里程焦虑圣地亚哥

RNA m^(6)A reader YTHDF2 facilitates precursor miR-126 maturation to promote acute myeloid leukemia progression

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Genes & Diseases 2024年第1期11卷 382-396页

作者： Zheng Zhang Keren Zhou Li Han Andrew Small Jianhuang Xue Huilin Huang Hengyou Weng Rui Su Brandon Tan chao Shen Wei Li Zhicong Zhao Ying Qing Xi Qin Kitty Wang keith Leung Mark Boldin chun-Wei chen David Ann Zhijian Qian Xiaolan Deng Jianjun chen Zhenhua chen Department of Systems Biology Beckman Research Institute of City of HopeMonroviaCA 91016USA Irell and Manella Graduate School of Biological Sciences Beckman Research Institute of City of HopeDuarteCA 91010USA Gehr Family center for Leukemia Research City of HopeDuarteCA 91010USA Sun Yat-sen University cancer center State Key Laboratory of Oncology in South ChinaCollaborative Innovation Center for Cancer MedicineGuangzhouGuangdong 510060China Guangzhou Laboratory GuangzhouGuangdong 510005China Bioland Laboratory GuangzhouGuangdong 51005China Department of Liver Surgery Renji HospitalShanghai Jiao Tong University School of MedicineShanghai 200127China Department of Diabetes complications and Metabolism Beckman Research Institute of City of HopeDuarteCA 91010USA Department of Biochemistry and Molecular Biology University of FloridaGainesvilleFL 32603USA Tongji Hospital Affiliated to Tongji University Frontier Science Center for Stem Cell ResearchSchool of Life Sciences and TechnologyTongji UniversityShanghai 200092China School of Pharmacy China Medical UniversityShenyangLiaoning 110001China

As the most common internal modification of mRNA,Ne-methyladenosine(m^(6)A)and its regulators modulate gene expression and play critical roles in various biological and patholog-ical processes including *** was reported previously that m^(6)A methyltransferase(writer),methyltransferase-like 3(METTL3)adds m^(6)A in primary microRNAs(pri-miRNAs)and fa-cilitates its processing into precursor miRNAs(pre-miRNAs).However,it is unknown whether m^(6)A modification also plays a role in the maturation process of pre-miRNAs and(if so)whether such a function contributes to ***,we found that YTHDF2 is aberrantly overexpressed in acute myeloid leukemia(AML)patients,especially in relapsed patients,and plays an onco-genic role in ***,YTHDF2 promotes expression of miR-126-3p(also known as miR-126,as it is the main product of precursor miR-126(pre-miR-126)),a miRNA that was reported as an oncomiRNA in AML,through facilitating the processing of pre-miR-126 into mature ***,YTHDF2 recognizes m^(6)A modification in pre-miR-126 and recruits AGO2,a regulator of pre-miRNA processing,to promote the maturation of ***2 posi-tively and negatively correlates with miR-126 and miR-126's downstream target genes,respec-tively,in AML patients,and forced expression of miR-126 could largely rescue YTHDF2/Ythdf2 depletion-mediated suppression on AML cell growth/proliferation and leukemogenesis,indi-cating that miR-126 is a functionally important target of YTHDF2 in ***,our studies not only reveal a previously unappreciated YTHDF2/miR-126 axis in AML and highlight the ther-apeutic potential of targeting this axis for AML treatment,but also suggest that m^(6)A plays a role in pre-miRNA processing that contributes to tumorigenesis.

关键词： AML miR-126 N^(6)-methyladenosine Pre-miRNA maturation YTHDF2

Ionic liquid electrolytes for sodium-ion batteries to control thermal runaway

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Journal of Energy chemistry 2023年第6期81卷 321-338,I0008页

作者： keith Sirengo Aswathy Babu Barry Brennan Suresh c.Pillai Nanotechnology and Bio-Engineering Research Group Department of Environmental ScienceAtlantic Technological UniversityATU SligoAsh LaneSligo F91 YW50Ireland Health and Biomedical(HEAL)Strategic Research centre Atlantic Technological UniversityATU SligoAsh LaneSligo F91 YW50Ireland

Sodium-ion batteries are expected to be more affordable for stationary applications than lithium-ion batteries,while still offering sufficient energy density and operational capacity to power a significant segment of the battery *** this,thermal runaway explosions associated with organic electrolytes have led to concerns regarding the safety of sodium-ion *** electrolytes,ionic liquids are promising because they have negligible vapor pressure and show high thermal and electrochemical *** review discusses the safety contributions of these electrolyte properties for high-temperature *** ionic liquids provide thermal stability while at the same time promoting high-voltage window battery ***,apart from cycle stability,there is an additional safety feature attributed to modified ultra-concentrated ionic liquid *** these contributions,the following have been discussed,heat sources and thermal runaway mechanisms,thermal stability,the electrochemical decomposition mechanism of stable cations,and the ionic transport mechanism of ultra-concentrated ionic liquid *** addition,the contributions of hybrid electrolyte systems consisting of ionic liquids with either organic carbonate or polymers are also *** thermal stability of ionic liquids is found to be the main contributor to cell safety and cycle *** high-temperature applications where electrolyte safety,capacity,and cycle stability are important,highly concentrated ionic liquid electrolyte systems are potential solutions for sodium-ion battery applications.

关键词： Thermal stability Ionic liquids Sodium-ion batteries cycle stability Ionic conductivity

SIMAP500: A novel risk score to identify recipients at higher risk of hepatocellular carcinoma recurrence following liver transplantation

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World Journal of Transplantation 2024年第3期14卷 132-143页

作者： Amr Alnagar Nekisa Zakeri Konstantinos Koilias Rosemary E Faulkes Rachel Brown Owen cain M Thamara P R Perera keith J Roberts Rebeca Sanabria-Mateos David c Bartlett Yuk Ting Ma Shivan Sivakumar Shishir Shetty Tahir Shah Bobby V M Dasari Department of HBP and Liver Transplantation Surgery Queen Elizabeth HospitalUniversity Hospitals BirminghamBirmingham B152GWUnited Kingdom centre for Liver Research Institute of Biomedical ResearchBirmingham B152TTUnited Kingdom Department of Hepatology Queen Elizabeth HospitalUniversity Hospitals BirminghamBirmingham B152GWUnited Kingdom Department of Pathology University Hospitals Birmingham NHS Foundation TrustBirmingham B152GWUnited Kingdom Department of Oncology Queen Elizabeth HospitalUniversity Hospitals of BirminghamBirmingham B152GWUnited Kingdom

BAcKGROUND Recurrence of hepatocellular carcinoma(Hcc)following liver transplantation(LT)has a devastating influence on recipients’survival;however,the risk of recur-rence is not routinely *** stratification is vital with a long LT waiting time,as that could influence the recurrence despite strict listing *** This study aims to identify predictors of recurrence and develop a novel risk pre-diction score to forecast Hcc recurrence following *** A retrospective review of LT for Hcc recipients at University Hospitals Bir-mingham between July 2011 and February *** and multivariate analyses were performed to identify recurrence predictors,based on which the novel SIMAP500(satellite nodules,increase in size,microvascular invasion,AFP>500,poor differentiation)risk score was *** 234 LTs for Hcc were performed with a median follow-up of 5.3 *** developed in 25 patients(10.7%).On univariate analyses,RETREAT score>3,α-fetoprotein(AFP)at listing 100-500 and>500,bridging,increased tumour size between imaging at the listing time and explant histology,increase in the size of viable tumour between listing and explant,presence of satellite nodules,micro-and macrovascular invasion on explant and poor differentiation of tumours were significantly associated with recurrence,based on which,the SIMAP500 risk score is *** SIMAP500 demonstrated an excellent predictive ability(c-index=0.803)and outper-formed the RETREAT score(c-index=0.73).SIMAP500 is indicative of the time to disease *** SIMAP500 risk score identifies the LT recipients at risk of Hcc *** stratification allows patient-centric post-transplant surveillance *** validation of the score is recommended.

关键词： Liver transplantation Hepatocellular carcinoma Recurrence Survival

Five Principles as Relevant Today as 70 Years Ago

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Embracing the Year ofthe Dragon

今日中国（英文版） 2024年第8期 18页

作者： keith BENNETT

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Forest composition and red oak (Quercus sp.) response to elevation gradients across greentree reservoirs

今日中国（英文版） 2024年第2期

作者： keith BENNETT

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Forest Ecosystems 2023年第5期10卷 607-617页

作者： cassandra Hug Pradip Saud keith McKnight Douglas c.Osborne college of Forestry Agriculturaland Natural ResourcesUniversity of Arkansas at MonticelloMonticelloAR71656USA USFWS/Lower Mississippi Valley Joint Venture TylerTX75707USA Five Oaks Ag Research and Education center HumphreyAR72073USA

Elevation gradients within forested wetlands have long been recognized for their role in defining species composition through factors such as hydrology and soil *** reservoirs(GTRs)are leveeimpounded tracts of bottomland hardwood forest flooded throughout the winter months to provide habitat for overwintering *** flooding of GTRs alters the forest composition due to flood frequency,depth,and duration in combination with slight changes in *** evaluate the effect of elevation gradients,soil properties,and management techniques in the overstory species composition and red oak(Quercus spp.)species abundance,we inventoried 662 plots across 12 independent GTRs in eastern *** the lower elevations ranging from 50.98 to 54.99 m above sea level,the importance value index(IVI)was highest for nuttall oak(Quercus texana)and overcup oak(Quercus lyrata),whereas IVI shifted to cherrybark oak(Quercus pagoda)in the higher elevations ranging from 54.99 to 58.00 *** diversity did not differ by elevation gradient,soil property,or management technique within *** diversity,using non-metric multi-dimensional scaling(NMDS)analysis,indicated site-specific variability significantly correlated with the environmental predictors,including elevation(R^(2)=0.57),easting(R^(2)=0.47),soil texture(R^(2)=0.21),and pH(R^(2)=0.12).Red oak species-specific mixed-effects modeling of abundance response using Poisson distribution suggested an inverse correlation of nuttall oak and a direct correlation of cherrybark oak abundance with ***,willow oak(Quercus phellos)abundance was not significantly affected by elevation but was by silt loam soil texture and restoration management *** findings will aid management efforts to reduce the dominance of less desirable species that are prominent under specific environmental conditions and promote the dominance of more desirable *** GTR sustainability is increas

关键词： Bottomland hardwoods Diversity Forested wetland Overstory Red oak Soil Thinning and management

Revisiting the death of geography in the era of Big Data:the friction of distance in cyberspace and real space

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International Journal of Digital Earth 2018年第5期11卷 451-469页

作者： Su Yeon Han Ming-Hsiang Tsou keith c.clarke Department of Geography San Diego State UniversitySan DiegoCAUSA Department of Geography University of CaliforniaSanta BarbaraCAUSA

Many scholars have argued that the importance of geographic proximity in human interactions has been diminished by the use of the Internet,while others disagree with this *** have noted the distance decay effect in both cyberspace and real space,showing that interactions occur with an inverse relationship between the number of interactions and the distance between the locations of the ***,these studies rarely provide strong evidence to show the influence of distance on interactions in cyberspace,nor do they quantify the differences in the amount of friction of distance between cyberspace and real *** fill this gap,this study used massive amounts of social media data(Twitter)to compare the influence of distance decay on human interactions between cyberspace and real space in a quantitative *** estimate the distance decay effect in both cyberspace and real space,the distance decay function of interactions in each space was *** the distance decay in cyberspace in this study can help predict the degree of information flow across space through social *** how far ideas can be diffused through social media is useful for users of location-based services,policy advocates,public health officials,and political campaigners.

关键词： First law of geography distance decay Big Data Twitter social media information diffusion

A novel secure multicast scheme in mobile Internet

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Journal of central South University of Technology 2005年第6期12卷 720-725页

作者：王国军廖麟曹建农 cHAN keith c.c. School of Information Science and Engineering Central South University Changsha 410083 China Department of Computing Hong Kong Polytechnic University Hung Hom Kowloon Hong Kong China School of Information Science and Engineering Central South University Changsha 410083 China Department of computing Hong Kong Polytechnic University Hung Hom Kowloon Hong Kong China

A novel multicast communication model using a RingNet hierarchy is proposed. The RingNet hierarchy consists of 4 tiers: border router tier, access gateway tier, access proxy tier and mobile host tier. Within the hierarchy, the upper 2 tiers are dynamically organized into logical rings with network entities. A novel hierarchical secure access control scheme on key management is proposed based on the RingNet model. Network entities within the multicast hierarchy belong to different privileged local groups. Network entities of the higher-privileged local groups have the right to derive the keys held by network entities of the lower-privileged local groups, and the reverse operation is not allowed. With the key management approach, any insertion and changing of local group key will not affect other local groups. The analytical result shows that the scheme has higher security than Lin’s.

关键词： key management access control related factor local group changing residue