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Reactive lymphoid hyperplasia of the liver:A case report and review of literature

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World Journal of Gastroenterology 2007年第40期13卷 5403-5407页

作者： Takuro Machida Toshiyuki Takahashi Tomoo Itoh Michiaki hirayama Takayuki Morita Shoichi Horita Department of Internal Medicine Hokkaido Gastroenterology HospitalSapporoHokkaido 065-0041Japan Department of Pathology Hokkaido Gastroenterology HospitalSapporoHokkaido 065-0041Japan Department of Pathology Hokkaido University HospitalSapporoHokkaido060-8648Japan Department of Surgery Hokkaido Gastroenterology HospitalSapporoHokkaido 065-0041Japan

有反应淋巴的增生(RLH ) 的一个 53 岁的女病人的一个盒子，肝的临床上指明的同样假的淋巴瘤在这篇文章被描述。病人为顺便说一下在另一所医院发现的肝的肿瘤的进一步的评估进入我们的医院。各种各样的诊断方法，包括的 ultrasonograph... 详细信息

有反应淋巴的增生(RLH ) 的一个 53 岁的女病人的一个盒子，肝的临床上指明的同样假的淋巴瘤在这篇文章被描述。病人为顺便说一下在另一所医院发现的肝的肿瘤的进一步的评估进入我们的医院。各种各样的诊断方法，包括的 ultrasonography (美国) ，计算机化的断层摄影术(CT ) ，磁性的回声成像(MRI ) 和肝的血管造影术与与肝细胞癌(HCC ) 一致的突出的调查结果在肝显示了三小损害。外科的切除术被执行，三损害是作为肝的 RLH 诊断的用显微镜。损害与滤泡和 hyalinized 包括了淋巴样细胞的巨大的渗入内部小囊的空格。Immunohistochemical 检查表明渗透的淋巴细胞没有突出的原子非典型和 polyclonality。肝的 RLH 是一个很稀罕的条件，仅仅 12 个案例在英语文学被报导了。报导案例的多数是中年的女人并且关于他们的一半有象自体免疫的甲状腺炎那样的一些免疫逻辑畸形， Sjogren 的症候群，主要免疫不全，主要胆汁性肝硬变。因为他们临床上经常作为 HCC 被误诊，外科是为这些病人的治疗的选择。尽管他们的病理类似于恶性淋巴瘤，临床的功课是完全良性的。作者建议肝的 RLH 能被它的临床的特征从 HCC 区别。

关键词：淋巴增大淋巴节肝细胞癌免疫组织化学

敦煌《毛诗音》反切中的“开合一致原则”及其在韵母拟音上的应用

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中国语文 2010年第3期 256-269页

作者：平山久雄日本东京大学文学部

本文作为平山久雄(2009)的续篇,介绍敦煌《毛诗音》残卷反切结构中的"开合一致原则"的统计基础,并说明应用这条结构原则对阐释一些韵母如鱼韵、东韵、覃韵、江韵等拟音问题的功用。"开合一致"表示反切上字和被切字开合一致。带"唇性韵尾... 详细信息

本文作为平山久雄(2009)的续篇,介绍敦煌《毛诗音》残卷反切结构中的"开合一致原则"的统计基础,并说明应用这条结构原则对阐释一些韵母如鱼韵、东韵、覃韵、江韵等拟音问题的功用。"开合一致"表示反切上字和被切字开合一致。带"唇性韵尾"/u/、/m/、/w/等的韵母不属开口或合口,而构成另一范畴"唇尾"。唇尾诸韵对"开合一致原则"表现出的性质因韵而有所不同,作者根据统计数据拟定每一唇尾韵的"合口度"。

关键词：敦煌残卷《毛诗音》开合反切结构《切韵》音系

Complete response to multidisciplinary therapy in a patient with primary gastric choriocarcinoma

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World Journal of Gastroenterology 2013年第31期19卷 5187-5194页

作者： Kazuhiro Takahashi Shigeki Tsukamoto Ken Saito Nobuhiro Ohkohchi Katsu hirayama Division of Gastro-enterological and Hepatobiliary Surgery and Organ Transplantation Department of Surgery University of Tsukuba Tsukuba 3058575 Japan Department of Surgery Hiraka General Hospital Yokote 0138610 Japan

Primary gastric choriocarcinoma is a rapidly growing neoplasm with an average survival of several months in untreated *** with lymph node dissection followed by chemotherapy is the treatment of *** used for gastric adenocarcinoma are usually ***,median survival remains less than six *** this case report,we describe a case of primary gastric choriocarcinoma with a clinical complete response to multidisciplinary treatment including surgery,chemotherapy,and radiofrequency ablation(RFA).The patient was originally referred for general *** demonstrated a large tumor occupying the fornix,and total gastrectomy with lymph node dissection was *** days later,multiple liver metastatic recurrences with high serum levels of beta-human chorionic gonadotropin(β-hCG) were *** with a gonadal choriocarcinoma regimen consisting of etoposide,methotrexate,actinomycin D,cyclophosphamide,and vincristine(EMA/CO),was *** three cycles,serum β-hCG decreased markedly and the tumors *** months later,multiple lung metastatic recurrences were *** one cycle of EMA/CO,only one nodule *** tomography-guided RFA was performed for this oligometastatic *** patient has been alive with no evidence of disease for 10 years after the initial *** the best of our knowledge,this patient with recurrent primary gastric choriocarcinoma has achieved the longest *** present case is the first report of choriocarcinoma metastatic to the lung successfully treated with *** our retrospective analysis of recurrent or unresectable primary gastric choriocarcinoma,we propose that gonadal choriocarcinoma regimens can be considered as first-line for primary gastric choriocarcinoma.

关键词： Primary gastric choriocarcinoma Betahuman chorionic gonadotropin Etoposide,methotrexate,actinomycin D,cyclophosphamide,and vincristine Oligometastatic Radiofrequency ablation

Cardiogenic Shock Caused by a Large Sub-Epicardial Hematoma Complicating Percutaneous Coronary Intervention

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Case Reports in Clinical Medicine 2015年第6期4卷 233-236页

作者： Yoshiharu Higuchi Daisuke Fukamachi Nobuyuki Fujii Toshihiko Nishida Atsushi hirayama Division of Cardiology Department of Medicine Nihon University School of Medicine Tokyo Japan

A 56-year-old man with a history of old myocardial infarction and coronary artery bypass grafting was performed percutaneous coronary intervention to the totally occluded lesion of native left anterior descending artery. He developed a coronary arterial perforation that led to a large dissecting sub-epicardial hematoma. Emergent surgery was performed, and a large hematoma was removed from the sub-epicardial space. Continuous drainage of blood was observed after surgery, and the patient died due to the development of multiorgan dysfunction. An autopsy revealed an extensive sub-epicardial hematoma on the lateral wall of the left ventricle and broad necrosis of the myocardium in the lateral wall.

关键词： Sub-Epicardial Hematoma Cardiac Tamponade Percutaneous Coronary Intervention Coronary Artery Bypass Grafting

glpK和rpoC基因突变对大肠杆菌生长的调节机制

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glpK和rpoC基因突变对大肠杆菌生长的调节机制

第十八届全国波谱学学术年会

作者： Kian-Kai Cheng Baek-Seok Lee Takeshi Masuda Takuro Ito Kazutaka Ikeda Akiyoshi hirayama Lingli Deng Jiyang Dong kazuyuki Shimizu Tomoyoshi Soga Masaru Tomita Bernhard O.Palsson Martin Robert Institute for Advanced Biosciences Keio UniversityTsuruokaYamagata 997-0017Japan Systems Biology Program Graduate School of Media and GovernanceKeio UniversityKanagawa 252-8520Japan Institute of Bioproduct Development & Department of Bioprocess Engineering Universiti Teknologi Malaysia81310 JohorMalaysia PRESTO Japan Science and Technology AgencyKawaguchiSaitama 332-0012Japan Department of Electronic Science Xiamen University Kyushu Institute of Technology IizukaFukuoka820-8502Japan Department of Bioengineering University of CaliforniaSan DiegoLa JollaCA 92093-0412USA

＜正＞自2006年开始,基因组的重新测序有效地鉴定了细菌适于新环境时所引起的基因突变[1]。然而,相关的促生长机制还没有得到很好的诠释。本文联合利用代谢组学、蛋白质组学和脂类组学的方法对适于甘油的进化菌株中的glpK和rpoC两个基...

＜正＞自2006年开始,基因组的重新测序有效地鉴定了细菌适于新环境时所引起的基因突变[1]。然而,相关的促生长机制还没有得到很好的诠释。本文联合利用代谢组学、蛋白质组学和脂类组学的方法对适于甘油的进化菌株中的glpK和rpoC两个基因突变[2,3]的促生长机制进行深入研究,结果表明:进化大肠杆菌细胞株是通过两种不同的代谢方式来实现在甘油培基内更快的增长。首先,rpoC基因27bp的缺失提高了

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论“他的年纪比我大”类“比”字句

汉语学习 2014年第3期 51-57页

作者：平山邦彦拓殖大学外国语学部

本文探讨"X的N比YW"格式类"比"字句,如"他的年纪比我大"。本文着眼于比较项X/Y和比较点N的语义关系,对这类"比"字句成立的条件进行了探讨。经探讨发现:对于这类"比"字句,从X/Y的词汇意义或借助于"X比YNW"的结构意义,可以看出N在X/Y的支... 详细信息

本文探讨"X的N比YW"格式类"比"字句,如"他的年纪比我大"。本文着眼于比较项X/Y和比较点N的语义关系,对这类"比"字句成立的条件进行了探讨。经探讨发现:对于这类"比"字句,从X/Y的词汇意义或借助于"X比YNW"的结构意义,可以看出N在X/Y的支配域中具有显著性,同时X/Y和N之间存在"整体—部分"的关系,而这种显著性和"整体—部分"关系是这类"比"字句能够成立的一个必要条件。

关键词： X的N比YW 支配域显著性整体—部分

试谈汉语介词短语状语的语序规则——从语义结合力的角度谈起

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汉语学习 2018年第3期 25-32页

作者：平山邦彦拓殖大学外国语学部日本东京1930985

现代汉语中介词短语为一种代表性的状语格式,其所处位置可在主语前后。介词短语从语序分布看有三种情况:介词短语(Ⅰ)只能采用后者语序;介词短语(Ⅱ)前后两种语序都可以采用;介词短语(Ⅲ)只能采用前者语序。文章对形成这一现象的核心因... 详细信息

现代汉语中介词短语为一种代表性的状语格式,其所处位置可在主语前后。介词短语从语序分布看有三种情况:介词短语(Ⅰ)只能采用后者语序;介词短语(Ⅱ)前后两种语序都可以采用;介词短语(Ⅲ)只能采用前者语序。文章对形成这一现象的核心因素从语义结合力角度进行探讨发现:介词短语(Ⅰ)(Ⅱ)(Ⅲ)在语义结合力以及谓语对介词宾语的施事性或受事性的凸显程度上存在差异,其对介词短语状语呈三种不同的语序倾向起关键作用。这是语义靠近原理共性语序规则在汉语中作为语言个性的充分体现。

关键词：介词短语语义结合力施事性受事性凸显

A case of Bickerstaff brainstem encephalitis successfully treated with intravenous immunoglobulin and methylprednisolone after unsuccessful immunoadsorption plasmapheresis

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Open Journal of Clinical Diagnostics 2013年第1期3卷 1-4页

作者： Takeshi Imai Takahiro Shimizu Yuta Hagiwara Toshikazu hirayama Yasuhiro Hasegawa Department of Internal Medicine Division of Neurology St. Marianna University School of Medicine Kawasaki Japan

Bickerstaff brainstem encephalitis (BBE) is a rare post-infectious neurological syndrome for which an effective treatment strategy has not been established. Here, we report a case of a 71-year-old male who suffered from an upper respiratory tract infection, and 7 days later, developed numbness of the bilateral upper and lower limbs, unsteady gait and dysarthria. Brain magnetic resonance imaging was normal, nerve conduction study and cerebral spinal fluid analysis were nonspecific. Based on the clinical features, we tentatively diagnosed Guillain-Barré syndrome and started immunoadsorption plasmapheresis. However, consciousness progressively declined to coma level within 10 days. Electroencephalogram showed diffuse slowing, and auditory evoked brainstem response (ABR) demonstrated absence of waves II, III and V. Serum anti-GQ1b IgG autoantibody and anti-GM1b IgG autoantibody were negative. Subsequently, we diagnosed BBE, and clinical symptoms resolved after treatment with intravenous immunoglobulin and methyllprednisolone. On day 62, neurological symptoms were remarkably alleviated with an improvement in ABR. Our observations suggest that immunoadsorption plasmapheresis should be used only when anti-ganglioside antibodies are detected. Combination therapy with intravenous immunoglobulin and methylprednisolone or plasma exchange?is recommended as initial therapy.

关键词： Bickerstaff Brainstem Encephalitis Intravenous Immunoglobulin Methylprednisolone Immunoadsorption Plasmapheresis

Plasma-Electrolysis of Dinitrophenol in Gas-Liquid Boundary and Interpretation Using Molecular Orbital Theory

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World Journal of Engineering and Technology 2019年第1期7卷 141-157页

作者： Hiroshi Okawa Hiroki Kuroda Keiko hirayama-Katayama Shin-Ichiro Kojima Tetsuya Akitsu Happy Science University Chosei-Chiba Japan University of Yamanashi Kofu Japan Kyushu University Fukuoka Japan

The advanced oxidation of 2,4-dinitrophenol (DNP), 2,5-DNP, and 3,4-DNP in aqueous solution has been investigated using a multi-gas, dielectric barrier discharge. Dielectric barrier discharge was operated in the aqueous solution and gas boundary. The degradation was measured by high performance liquid chromatography (HPLC). The acceleration of the advanced-oxidation has been investigated by the combination of the anion exchange polymer membrane. The result indicated that the degradation pathways involve a rapid detachment of the nitro group and a slow opening of the aromatic-ring. The hydroxyl radical and the excited hydroxyl anion are responsible for the primary attack of the DNP with the production of dihydroxy-nitrobenzenes. The attack of hydroxyl radical occurs at the benzene ring carbon activated by the presence of a phenolic OH group and a nitro group. The result suggested that the reaction is dominated by a pseudo-first order kinetic reaction. The degradation process is interpreted using Molecular Orbital Theory.

关键词： Dielectric Barrier Discharge Dinitrophenol Advanced Oxidation Molecular Orbital Theory