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Towards a natural classification and backbone tree for Lophiostomataceae,Floricolaceae,and Amorosiaceae ***.

Fungal Diversity 2015年第5期74卷 199-266页

作者： Kasun M.Thambugala Kevin D.Hyde Kazuaki Tanaka Qing Tian Dhanushka N.Wanasinghe Hiran A.Ariyawansa Subashini C.Jayasiri Saranyaphat Boonmee Erio Camporesi Akira Hashimoto kazuyuki hirayama RenéK.Schumacher Itthayakorn Promputtha Zuo-Yi Liu Guizhou Key Laboratory of Agricultural Biotechnology Guizhou Academy of Agricultural SciencesGuiyangGuizhou 550006People’s Republic of China Center of Excellence in Fungal Research Chiang Rai 57100Thailand School of Science Mae Fah Luang UniversityChiang Rai 57100Thailand Key Laboratory for Plant Diversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of ScienceKunming 650201YunnanChina Faculty of Agriculture and Life Sciences Hirosaki University3 Bunkyo-cho HirosakiAomori 036-8561Japan The United Graduate School of Agricultural Sciences Iwate University18-8 Ueda 3 chomeMorioka 020-8550Japan Apple Experiment Station Aomori Prefectural Agriculture and Forestry Research Center24 FukutamiBotandairaKuroishiAomori 036-0332Japan Department of Biology Faculty of ScienceChiang Mai UniversityChiang Mai 50200Thailand A.M.B.Gruppo Micologico Forlivese BAntonio Cicognani Via Roma 18ForlìItaly A.M.B.Circolo Micologico BGiovanni Carini C.P.314 BresciaItaly Hölderlinsraße 25 15517 Fürstenwalde/SpreeGermany

The genera Lophiostoma,Misturatosphaeria and several other allied taxa in Lophiostomataceae are *** of these taxa,including their history,morphology,and family placement,based on molecular phylogeny,are *** or representative specimens of Lophiostoma and Misturatosphaeria were examined and fresh specimens were obtained from Germany,Italy,Japan and Thailand.A multi-gene phylogenetic analysis of the lophiostomataceous genera Floricola,Lophiostoma,Misturatosphaeria and related taxa is *** genera including Lophiostoma,Lophiohelichrysum,Dimorphiopsis,Platystomum and Vaginatispora,plus eleven newly introduced genera Biappendiculispora,Alpestrisphaeria,Capulatispora,Coelodictyosporium,Guttulispora,Lophiopoacea,Neotrematosphaeria,Paucispora,Pseudolophiostoma,Pseudoplatystomum and Sigarispora are accepted in Lophiostomataceae based on morphology and *** caulium,Lophiostoma arundinis and Lophiostoma caudatum are accommodated in *** winteri and Lophiostoma fuckelii are placed in the genera Lophiopoacea and Vaginatispora *** Curreya species and Misturatosphaeria claviformis are transferred to a new genus,*** other Misturatosphaeria species except Misturatosphaeria aurantiinotata and *** are separated in the new genera Asymmetrispora,Aurantiascoma,Magnibotryascoma,Pseudoaurantiascoma and Pseudomisturatosphaeria based on their morphological and phylogenetic *** new genus,Ramusculicola is introduced for a new collection from *** seven new genera are accommodated in a new family Floricolaceae,together with Floricola and *** massarina-like species clustered as a sister clade to Amorosia littoralis and are accommodated in a new genus Angustimassarina.A new family Amorosiaceae is proposed to accommodate the genera Amorosia and *** putatively named species Decaisnella formosa and Thyridaria macrostomoides form a s

关键词： Dothideomycetes Floricola Lophiostoma Misturatosphaeria Multi-gene phylogeny new species new genus Pleosporales taxonomy

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Dictyosporiaceae ***.

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Fungal Diversity 2016年第5期80卷 457-482页

作者： Saranyaphat Boonmee Melvina J.D’souza Zonglong Luo Umpava Pinruan Kazuaki Tanaka Hongyan Su Darbhe J.Bhat Eric H.C.McKenzie E.B.Gareth Jones Joanne E.Taylor Alan J.L.Phillips kazuyuki hirayama Prapassorn D.Eungwanichayapant Kevin D.Hyde Center of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand School of Science Mae Fah Luang UniversityChiang Rai 57100Thailand College of Agriculture and Biology Sciences Dali UniversityDaliYunnan 671003China National Center for Genetic Engineering and Biotechnology National Science and Technology Development AgencyThailand Science Park113 Phahonyothin RoadKlong 1Klong Luang Pathumthani 12120Thailand Formerly Department of BotanyGoa UniversityNo.128/1-JAzad Housing SocietyCurca Goa VelhaIndia Manaaki Whenua Landcare Research Private Bag 92170AucklandNew Zealand Faculty of Sciences Biosystems and Integrative Sciences Institute(BioISI)University of LisbonCampo Grande1749-016 LisbonPortugal Royal Botanic Garden Edinburgh 20A Inverleith RowEdinburgh EH35LRUK Department of Botany and Microbiology College of ScienceKing Saud UniversityP.O.Box:2455Riyadh 1145Saudi Arabia Faculty of Agriculture and Life Science Hirosaki University3 Bunkyo-choHirosakiAomori 036-8561Japan Apple Experiment Station Aomori Prefectural Agriculture and Forestry Research Center24 FukutamiBotandairaKuroishiAomori 036-0332Japan

Dictyosporiaceae *** introduced to accommodate a holomorphic group of Dothideomycetes that are saprobes on decaying wood and plant debris in terrestrial and freshwater *** sexual morph comprises Dictyosporium meiosporum,***,Gregarithecium curvisporum,Pseudocoleophoma calamagrostidis and *** sexual morphs are characterized by immersed to erumpent,superficial,globose to subglobose,dark brown to black ascomata,bitunicate asci,and septate,hyaline,sheathed *** asexual morphs are hyphomycetous with brown,multi-septate,cheirosporous conidia,produced from holoblastic conidiogenous cells,on micronematous *** analyses of LSU,SSU and TEF1 sequence data place the genera with cheirospores in a monophyletic clade in the order *** analyses based on ITS sequence data show the family to comprise 44 distinct lineages that correspond to ten genera and an undetermined *** new genera Dictyocheirospora,Dictyopalmispora,Jalapriya and Vikalpa,and eight new species Dictyocheirospora bannica,***,***,Dictyopalmispora palmae,Dictyosporium olivaceosporum,***,Jalapriya pulchra,and Vikalpa lignicola,are introduced in the family.

关键词： Cheirosporous conidia KeylPhylogeny Sexual states Sporodochial fungi

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Nanotwin-assisted nitridation of quenched FeNi alloy nanopowders for rare-earth-free magnets

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Journal of Materials Science & Technology 2023年第34期165卷 244-252页

作者： Jian Wang Yusuke hirayama kazuyuki Suzuki Kwangjae Park Zheng Liu Kenta Takagi Kimihiro Ozaki Innovative Functional Materials Research Institute National Institute of Advanced Industrial Science and Technology4-205SakurazakaMoriyamaNagoya463-8560Japan

L1_(0)-ordered FeNi alloy with a high uniaxial magnetic anisotropy and large magnetic moment is a promising candidate for rare-earth-free permanent magnets ***,the synthesis of this chemically ordered phase remains a longstanding challenge because of its low chemical order-disorder transition temperature(200-320℃).Although a non-equilibrium synthetic route based on a nitrogen topotactic reaction has been proposed as a valid approach,the volume fraction and degree of chemical ordering of the product phase are ***,we propose a promising approach that promotes the efficient formation of L1_(0)-ordered nitride phase in FeNi nanopowders by introducing a quenching treatment during a low-oxygen induction thermal plasma *** quenched FeNi nanopowders possessed much smaller powder sizes(40.4 vs 74.0 nm),exhibited higher number densities of nanotwins(39.8%vs 24.1%)and formed much larger volume fraction(33.6 wt.%vs 0.6 wt.%)of ordered phase than the unquenched ***,quenching-induced high-density nanotwins led to the dominant coverage of serrated{001}crystal facets over the surfaces of the FeNi *** unique features substantially accelerated the formation of the L1_(0)-ordered nitride phase in the FeNi nanopowders because the{001}crystallographic orientation had the highest nitrogen *** work provides not only a valid synthetic approach for mass production of the L10-ordered nitride phase in FeNi nanopowders but also novel insights into the crystal-defect-assisted nitridation of nanomaterials.

关键词： Rare-earth-free Permanent magnet FeNi Nitridation Nanotwin

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Atomically precise thiolate-protected gold nanoclusters:Current status of designability of the structure and physicochemical properties

聚集体(英文)

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聚集体(英文) 2023年第2期4卷 1-41页

作者： Sakiat Hossain Daisuke hirayama Ayaka Ikeda Mai Ishimi Sota Funaki Arpan Samanta Tokuhisa Kawawaki Yuichi Negishi Research Institute for Science and Technology Tokyo University of ScienceShinjuku-kuJapan Department of Applied Chemistry Faculty of ScienceTokyo University of ScienceShinjuku-kuJapan

Thiolate(SR)-protected gold nanoclusters(Aun(SR)m NCs)are a rare type of material capable of simultaneously exhibiting multiple physicochemical properties well-suited to specific applications,including photoluminescence,thermocatalysis,electrocatalysis,photocatalysis,magnetism,and optical *** the past several decades,there has been tremendous progress in our understanding of the structure and physicochemical properties of Aun(SR)m NCs,resulting in the ability to fine-tune the characteristics of these *** is therefore helpful to examine the extent to which the properties of Aun(SR)m and related metal NCs can now be adjusted based on *** review presents representative examples of previous studies concerning the geometry,electronic structure,luminescence properties,catalysis,magnetism and optical activity of Aun(SR)m and related metal NCs and discusses the current status of the designability of these NCs to impart specific structural and physicochemical *** information is expected to accelerate the fabrication of highly functional materials based on Aun(SR)m and related metal NCs.

关键词： atomically precise metal nanoclusters gold nanoclusters physicochemical properties structures thiolate

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Families of Dothideomycetes

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Fungal Diversity 2013年第6期63卷 1-313页

作者： Kevin D.Hyde E.B.Gareth Jones Jian-Kui Liu Hiran Ariyawansa Eric Boehm Saranyaphat Boonmee Uwe Braun Putarak Chomnunti Pedro W.Crous Dong-Qin Dai Paul Diederich Asha Dissanayake Mingkhuan Doilom Francesco Doveri Singang Hongsanan Ruvishika Jayawardena James D.Lawrey Yan-Mei Li Yong-Xiang Liu Robert Lücking Jutamart Monkai Lucia Muggia Matthew P.Nelsen Ka-Lai Pang Rungtiwa Phookamsak Indunil C.Senanayake Carol A.Shearer Satinee Suetrong Kazuaki Tanaka Kasun M.Thambugala Nalin N.Wijayawardene Saowanee Wikee Hai-Xia Wu Ying Zhang Begoña Aguirre-Hudson S.Aisyah Alias AndréAptroot Ali H.Bahkali Jose L.Bezerra D.Jayarama Bhat Erio Camporesi Ekachai Chukeatirote Cécile Gueidan David L.Hawksworth kazuyuki hirayama Sybren De Hoog Ji-Chuan Kang Kerry Knudsen Wen-Jing Li Xing-Hong Li Zou-Yi Liu Ausana Mapook Eric H.C.McKenzie Andrew N.Miller Peter E.Mortimer Alan J.L.Phillips Huzefa A.Raja Christian Scheuer Felix Schumm Joanne E.Taylor Qing Tian Saowaluck Tibpromma Dhanushka N.Wanasinghe Yong Wang Jian-Chu Xu Supalak Yacharoen Ji-Ye Yan Min Zhang Key Laboratory for Plant Biodiversity and Biogeography of East Asia(KLPB) Kunming Institute of BotanyChinese Academy of ScienceKunming 650201Yunnan China World Agroforestry Centre East Asia NodeHeilongtanKunming 650201China Institute of Excellence in Fungal Research Chiang Rai 57100Thailand School of Science Mae Fah Luang UniversityChiang Rai 57100Thailand Institute Ocean Earth Sciences Kuala Lumpur 50603SelangorMalaysia Department of Botany and Microbiology King Saudi UniversityRiyadhSaudi Arabia 42 Longacre Drive LivingstonNJ 07039USA Institut für Biologie Bereich Geobotanik und Botanischer GartenHerbariumMartin-Luther-UniversitätNeuwerk 2106099 Halle(Saale)Germany CBS-KNAW Fungal Biodiversity Centre Uppsalalaan 83584CT UtrechtThe Netherlands Musée National d’histoire Naturelle 25 rue Munster2160 LuxembourgLuxembourg Institute of Plant and Environment Protection Beijing Academy of Agriculture and Forestry SciencesBeijing 100097People’s Republic of China Via dei Funaioli 22 57126 LivornoItaly Department of Environmental Science and Policy George Mason University4400 University DriveFairfaxVA 22030-4444USA International Fungal Research and Development Centre Key Laboratory of Resource Insect Cultivation&Utilization State Forestry AdministrationKunming 650224People’s Republic of China The Research Institute of Resource Insects Chinese Academy of ForestryKunming 650224People’s Republic of China Guizhou Key Laboratory of Agricultural Biotechnology Guizhou Academy of Agricultural SciencesGuiyangGuizhou 550006People’s Republic of China Science and Education Integrative Research(Botany)The Field Museum1400 South Lake Shore DriveChicagoIL 60605-2496USA Institute of Plant Sciences University of GrazHolteigasse 68010 GrazAustria Department of Life Science University of TriesteVia L.Giorgieri 10TriesteItaly Committee on Evolutionary Biology University of Chicago1025 E.57th StreetChicagoIL 60637USA Institute ofMarine Biology and Center of Excellence for the Oceans Taiwan

Dothideomycetes comprise a highly diverse range of fungi characterized mainly by asci with two wall layers(bitunicate asci)and often with fissitunicate *** species are saprobes,with many asexual states comprising important plant *** are also endophytes,epiphytes,fungicolous,lichenized,or lichenicolous *** occur in terrestrial,freshwater and marine habitats in almost every part of the *** accept 105 families in Dothideomycetes with the new families Anteagloniaceae,Bambusicolaceae,Biatriosporaceae,Lichenoconiaceae,Muyocopronaceae,Paranectriellaceae,Roussoellaceae,Salsugineaceae,Seynesiopeltidaceae and Thyridariaceae introduced in this *** family is provided with a description and notes,including asexual and asexual states,and if more than one genus is included,the type genus is also *** family is provided with at least one figure-plate,usually illustrating the type genus,a list of accepted genera,including asexual genera,and a key to these genera.A phylogenetic tree based on four gene combined analysis add support for 64 of the families and 22 orders,including the novel orders,Dyfrolomycetales,Lichenoconiales,Lichenotheliales,Monoblastiales,Natipusillales,Phaeotrichales and *** paper is expected to provide a working document on Dothideomycetes which can be modified as new data comes to *** is hoped that by illustrating types we provide stimulation and interest so that more work is carried out in this remarkable group of fungi.

关键词： Acrospermales Asterinales Botryosphaeriales Capnodiales Dothideales Dyfrolomycetales Hysteriales Jahnulales Lichenoconiales Lichenotheliales Microthyriales Monoblastiales Myriangiales Mytilinidiales Natipusillales Patellariales Phaeotrichales Phylogeny Pleosporales Strigulales Taxonomy Trypetheliales Tubeufiales Type species Venturiales

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Exact Bosonic Solutions of the Truncated Skyrme Model

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Chinese Physics Letters 2010年第6期27卷 35-36页

作者： SHI Chang-Guang hirayama Minoru Department of Mathematics and Physics Shanghai University of Electric Power Shanghai 200090 Department of Physics University of Toyama Gofuku 3190 Toyama Japan

A model defined by half the Lagrangian （the highly nonlinear part） of the Skyrme model is investigated. Two classes of bosonic solutions are obtained. It is shown that, although the field configurations of these two... 详细信息

关键词： Models Solutions Model

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Degradation of dibromophenols by UV irradiation

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Journal of Environmental Sciences 2014年第6期26卷 1284-1288页

作者： Keiko Katayama-hirayama Naoki Toda Akihiko Tauchi Atsushi Fujioka Tetsuya Akitsu Hidehiro Kaneko Kimiaki hirayama Interdisciplinary Graduate School of Medicine and Engineering University of Yamanashi 4-3-11 Takeda Kofu 400-8511 Japan Technology Development Division Toshiba Lighting and Technology Corporation Asahimachi 5-2-1 Imabari Ehime 794-8510 Japan

We examined the degradation of dibromophenols （DBPs）, i.e. 2,4-DBP, 2,6-DBP and 3,5-DBP by ultraviolet （UV） irradiation and estimated the relationship between degradability and molecular orbital properties of each dibromopbenol. The removal of DBPs under a UV lamp system was successfully performed in an aqueous solution. After 5 min of irradiation, the initial DBPs concentration of 20 mg/L was decreased to below 1 mg/L, and about 60% of bromide ion was released. A decrease in the concentration of dissolved organic carbon （DOC） suggested the mineralization of DBPs, The mineralization may occur after release of bromide ions because the decrease of DOC was slower than the release of bromide ions. The degradability of 3,5-DBP was slightly lower than 2,6-DBP and 2,4-DBE Molecular orbital calculation suggested that the electrophilic frontier density and the highest occupied molecular orbital （HOMO） energy may be related to the degradability of DBPs.

关键词： bromide ion dibromophenol DOC mineralization UV irration

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Fungal diversity notes 1–110:taxonomic and phylogenetic contributions to fungal species

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Fungal Diversity 2015年第3期72卷 1-197页

作者： Jian Kui Liu Kevin D.Hyde E.B.Gareth Jones Hiran A.Ariyawansa Darbhe J.Bhat Saranyaphat Boonmee Sajeewa S.N.Maharachchikumbura Eric H.C.McKenzie Rungtiwa Phookamsak Chayanard Phukhamsakda Belle Damodara Shenoy Mohamed A,Abdel-Wahab Bart Buyck Jie Chen K.W.Thilini Chethana Chonticha Singtripop Dong Qin Dai Yu Cheng Dai Dinushani ADaranagama Asha J.Dissanayake Mingkwan Doilom Melvina J.D’souza Xin Lei Fan Ishani DGoonasekara kazuyuki hirayama Sinang Hongsanan Subashini C.Jayasiri Ruvishika S.Jayawardena Samantha C.Karunarathna Wen Jing Li Ausana Mapook Chada Norphanphoun Ka Lai Pang Rekhani H.Perera Derek Peršoh Umpava Pinruan Indunil CSenanayake Sayanh Somrithipol Satinee Suetrong Kazuaki Tanaka Kasun M.Thambugala Qing Tian Saowaluck Tibpromma Danushka Udayanga Nalin N.Wijayawardene Dhanuska Wanasinghe Komsit Wisitrassameewong Xiang Yu Zeng Faten AAbdel-Aziz Slavomir Adamčík Ali H.Bahkali Nattawut Boonyuen Timur Bulgakov Philippe Callac Putarak Chomnunti Katrin Greiner Akira Hashimoto Valerie Hofstetter Ji Chuan Kang David Lewis Xing Hong Li Xing Zhong Liu Zuo Yi Liu Misato Matsumura Peter E.Mortimer Gerhard Rambold Emile Randrianjohany Genki Sato Veera Sri-Indrasutdhi Cheng Ming Tian Annemieke Verbeken Wolfgang von Brackel Yong Wang Ting Chi Wen Jian Chu Xu Ji Ye Yan Rui Lin Zhao Erio Camporesi Guizhou Key Laboratory of Agricultural Biotechnology Guizhou Academy of Agricultural SciencesGuiyang 550006GuizhouChina Key Laboratory for Plant Diversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of ScienceKunming 650201YunnanChina Institute of Excellence in Fungal Research and School of Science Mae Fah Luang UniversityChiang Rai 57100Thailand Department of Botany and Microbiology King Saudi UniversityRiyadhSaudi Arabia Manaaki Whenua Landcare Research Private Bag 92170AucklandNew Zealand Formerly Department of Botany Goa UniversityGoaIndia No.128/1–J Azad Housing SocietyCurcaGoa VelhaIndia Muséum national d’histoire naturelle Dépt.Systématique etévolutionUMR 720575005 ParisFrance Institute of Microbiology&Beijing Key Laboratory for Forest Pest Control Beijing Forestry UniversityPO Box 61Beijing 100083China Institute of Plant and Environment Protection Beijing Academy of Agriculture and Forestry SciencesNo.9 of Shu Guang Hua Yuan Zhong LuHaidian DistrictBeijing 10097China The Key Laboratory for Silviculture and Conservation of Ministry of Education Beijing Forestry UniversityBeijing 100083China Mycology University of BayreuthUniversitätsstraße 3095440 BayreuthGermany The United Graduate School of Agricultural Sciences Iwate University18-8 Ueda 3 chomeMorioka 020-8550Japan Apple Experiment Station Aomori Prefectural Agriculture and Forestry Research Center24 FukutamiBotandairaKuroishiAomori 036-0332Japan Department of Plant Protection Agroscope Changins-Wadenswil Research Station ACWRte de Duiller1260 NyonSwitzerland Department of Botany and Microbiology College of ScienceKing Saud UniversityP.O.Box:2455Riyadh 1145Saudi Arabia Department of Botany Faculty of ScienceSohag UniversitySohagEgypt Institute of Botany Slovak Academy of SciencesDúbravskácesta 984523 BratislavaSlovakia Hirosaki University Bleakwood262 CR 3062NewtonTexas 75966USA Faculty of Agriculture and Life Sciences Hirosaki University3 Bunkyo-choHirosakiAomori

This paper is a compilation of notes on 110 fungal taxa,including one new family,10 new genera,and 76 new species,representing a wide taxonomic and geographic *** new family,Paradictyoarthriniaceae is introduced based on its distinct lineage in Dothideomycetes and its unique *** family is sister to Biatriosporaceae and *** new genera are Allophaeosphaeria(Phaeosphaeriaceae),Amphibambusa(Amphisphaeriaceae),Brunneomycosphaerella(Capnodiales genera incertae cedis),Chaetocapnodium(Capnodiaceae),Flammeascoma(Anteagloniaceae),Multiseptospora(Pleosporales genera incertae cedis),Neogaeumannomyces(Magnaporthaceae),Palmiascoma(Bambusicolaceae),Paralecia(Squamarinaceae)and Sarimanas(Melanommataceae).The newly described species are the Ascomycota Aliquandostipite manochii,Allophaeosphaeria dactylidis,***,Alternaria cesenica,Amphibambusa bambusicola,Amphisphaeria sorbi,Annulohypoxylon thailandicum,Atrotorquata spartii,Brunneomycosphaerella laburni,Byssosphaeria musae,Camarosporium aborescentis,***,***,Chaetocapnodium siamensis,Chaetothyrium agathis,Colletotrichum sedi,Conicomyces pseudotransvaalensis,Cytospora berberidis,***,Diaporthe thunbergiicola,Diatrype palmicola,Dictyosporium aquaticum,***,***,Didymella cirsii,Dinemasporium nelloi,Flammeascoma bambusae,Kalmusia italica,***,Keissleriella sparticola,Lauriomyces synnematicus,Leptosphaeria ebuli,Lophiostoma pseudodictyosporium,***,Lophiotrema eburnoides,Montagnula graminicola,Multiseptospora thailandica,Myrothecium macrosporum,Natantispora unipolaris,Neogaeumannomyces bambusicola,Neosetophoma clematidis,***,Oxydothis atypica,Palmiascoma gregariascomum,Paraconiothyrium nelloi,***,Paradictyoarthrinium tectonicola,Paralecia pratorum,Paraphaeosphaeria spartii,Pestalotiopsis digitalis,***,***,Phaeoisaria pseudoclematidis,Phragmocapnias philippinensis,Pseudocamarosporium cotinae,Pseudocercospora tam

关键词： Ascomycota Basidiomycota Global Taxonomy Initiative Phylogeny Taxonomy

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Machine Learning in Predicting Printable Biomaterial Formulations for Direct Ink Writing

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Research 2023年第4期2023卷 105-115页

作者： Hongyi Chen Yuanchang Liu Stavroula Balabani Ryuji hirayama Jie Huang Department of Mechanical Engineering University College LondonLondonUK Department of Computer Science University College LondonLondonUK Wellcome-EPSRC Centre for Interventional Surgical Sciences(WEISS) University College LondonLondonUK.

Three-dimensional(3D)printing is emerging as a transformative technology for biomedical *** 3D printed product can be patient-specific by allowing customizability and direct control of the *** trial-and-error approach currently used for developing the composition of printable inks is time-and resource-consuming due to the increasing number of variables requiring expert *** intelligence has the potential to reshape the ink development process by forming a predictive model for printability from experimental *** this paper,we constructed machine learning(ML)algorithms including decision tree,random forest(RF),and deep learning(DL)to predict the printability of biomaterials.A total of 210 formulations including 16 different bioactive and smart materials and 4 solvents were 3D printed,and their printability was *** ML methods were able to learn and predict the printability of a variety of inks based on their biomaterial *** particular,the RF algorithm has achieved the highest accuracy(88.1%),precision(90.6%),and F1 score(87.0%),indicating the best overall performance out of the 3 algorithms,while DL has the highest recall(87.3%).Furthermore,the ML algorithms have predicted the printability window of biomaterials to guide the ink *** printability map generated with DL has finer granularity than other *** has proven to be an effective and novel strategy for developing biomaterial formulations with desired 3D printability for biomedical engineering applications.

关键词： printing formulation biomaterials

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Evaluation of gut dysbiosis using serum and fecal bile acid profiles

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World Journal of Clinical Cases 2022年第34期10卷 12484-12493页

作者： Tadakuni Monma Junichi Iwamoto Hajime Ueda Makoto Tamamushi Fumio Kakizaki Naoki Konishi Shoichiro Yara Teruo Miyazaki Takeshi hirayama Tadashi Ikegami Akira Honda Department of Gastroenterology and Hepatology Tokyo Medical University Ibaraki Medical CenterInashiki-Gun 300-0395Japan Joint Research Center Tokyo Medical University Ibaraki Medical CenterInashiki-Gun 300-0395Japan

Dysbiosis in the intestinal microflora can affect the gut production of microbial metabolites,and toxic substances can disrupt the barrier function of the intestinal wall,leading to the development of various *** levels of Clostridium subcluster XIVa(XIVa)are associated with the intestinal dysbiosis found in inflammatory bowel disease(IBD)and Clostridium difficile infection(CDI).Since XIVa is a bacterial group responsible for the conversion of primary bile acids(BAs)to secondary BAs,the proportion of intestinal XIVa can be predicted by determining the ratio of deoxycholic acid(DCA)/[DCA+cholic acid(CA)]in feces *** example,serum DCA/(DCA+CA)was significantly lower in IBD patients than in healthy controls,even in the remission *** results suggest that a low proportion of intestinal XIVa in IBD patients might be a precondition for IBD onset but not a consequence of intestinal *** report showed that a reduced serum DCA/(DCA+CA)ratio could predict susceptibility to ***,the BA profile,particularly the ratio of secondary to primary BAs,can serve as a surrogate marker of the intestinal dysbiosis caused by decreased XIVa.

关键词： Gut dysbiosis Clostridium subcluster XIVa Bile acids HPLC-MS/MS Inflammatory bowel diseases Clostridium difficile infection

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