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PRIMARY WOUND CLOSURE OF DONOR SITE FOR ELDERLY PATIENTS WITH BURNS

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PRIMARY WOUND CLOSURE OF DONOR SITE FOR ELDERLY PATIENTS WIT...

Prior Somatic Stimulation Improves Performance of Acquired Motor Skill by Facilitating Functional Connectivity in Cortico-Subcortical Motor Circuits

Sino--Japanese Beijing International Symposium on Burns,1998

作者： Akira Sugamata Kousuke Shimanaka Hajime matsumura Burn Unit Plastic Surgery of Tokyo Medical College TokyoJapan

(Introduction) In operation of aged burn patients,it is difficult to cut split-skin grafts by using dermatome because of thinning of the skin with *** we have been performing aggressive donor size closure with dermoli...

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Journal of Behavioral and Brain Science 2012年第3期2卷 343-356页

作者： Shintaro Uehara Isao Nambu Michikazu matsumura Shinji Kakei Eiichi Naito Brain ICT Laboratory Advanced ICT Research Institute National Institute of Information and Communications Technology Kyoto Japan Center for Information and Neural Networks (CiNet) National Institute of Information and Communications Technology Kyoto Japan Graduate School of Human and Environmental Studies Kyoto University Kyoto Japan Tokyo Metropolitan Institute for Neuroscience Tokyo Japan

Once people have a well-trained motor skill, their performance becomes stabilized and achieving substantial improvement is difficult. Recently, we have shown that even a plateaued hand motor skill can be upgraded with short-period electrical stimulation to the hand prior to the task. Here, we identify the neuronal substrates underlying the improvement of the plateaued skill by examining the enhanced functional connectivity in the sensory-motor regions that are associated with motor learning. We measured brain activity using functional magnetic resonance imaging and performed psychophysiological interaction analysis. We recruited seven right-handed very-well trained participants, whose motor performance of continuously rotating two balls with their right hands became stabilized at higher performance levels. We prepared two experiments, in each of which they repeated an experimental run 16 times. In each run, they performed this cyclic rotation as many times as possible in 16 s. In the thenar-stimulation experiment, we applied 60-s stimulation to the thenar muscle before each of the 5th - 12th runs, and the others were preceded by ineffective sham stimulation. In the control experiment, the sham was always provided. Thenar stimulation enabled the participants to perform the movements at higher cycles. In association with this performance improvement, we found enhanced activity couplings between the primary motor cortex and the sensorimotor territory of the putamen and between the cerebellum and the primary sensorimotor cortices, without any quantitative activity increase. Neither behavioral change nor these increased activity couplings were observed in the ***, in contrast to the stable neuronal states in the cortico-subcortical motor circuits when the well-learned task is repeated at the later stages of motor skill learning, plastic changes in the motor circuits seem to be required when the plateaued skill is upgraded, and the stimulation may entail a state

关键词： Cortico-Subcortical Motor Circuit Primary Motor Cortex Basal Ganglia Cerebellum Motor Skill Learning Somatic Stimulation Neuronal Plasticity Functional Magnetic Resonance Imaging

大鼠延髓腹外侧注射食欲刺激素对动脉压和心率的影响

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中华高血压杂志 2008年第10期16卷 924-927页

作者：林英子金元哲 matsumura Kiyoshi 中国医科大学附属第四医院心血管内科辽宁沈阳110032 日本九州大学大学院病态机能内科学

目的探讨在大鼠延髓腹外侧注射食欲刺激素是否影响动脉压和心率。方法成熟雄性大鼠(n=19)腹腔内麻醉,微量注射食欲刺激素于延髓腹外侧头端(RVLM)及延髓腹外侧尾端(CVLM)内,记录动脉压和心率。用免疫组化的方法检测 RVLM、CVLM 内生长激... 详细信息

目的探讨在大鼠延髓腹外侧注射食欲刺激素是否影响动脉压和心率。方法成熟雄性大鼠(n=19)腹腔内麻醉,微量注射食欲刺激素于延髓腹外侧头端(RVLM)及延髓腹外侧尾端(CVLM)内,记录动脉压和心率。用免疫组化的方法检测 RVLM、CVLM 内生长激素促分泌素(GHS)受体蛋白的表达,并在显微镜下观察孤束核、RVLM、CVLM 区切片,记数阳性细胞数进行对比。结果微量注射食欲刺激素(0.4、0.8 mmol/L)于 RVLM内,可增加动脉压(+3.0±1.1)mmHg 和心率(+8.1±4.1)次/min,但差异没有统计学意义。同样微量注射食欲刺激素0.8 mmol/L 于 CVLM 内对动脉压[(-0.3±1.3)mmHg]及心率[(-5.0±3.3)次/min]的影响,差异也没有统计学意义。免疫组化显示孤束核[(38.7±3.6)%]、RVLM[(20.0±2.7)%]、CVLM[(24.7±1.6)%]内均有GHS 受体的分布。但是,孤束核的 GHS 受体阳性细胞数明显多于 RVLM、CVLM(P<0.05)。结论食欲刺激素在大鼠延髓腹外侧内对动脉压和心率影响不大。

关键词：食欲刺激素动脉压免疫组化生长激素促分泌素受体

Predicting Coronary Plaque Morphology Changes Based on Multimodality FSI Models Using Follow-Up IVUS and OCT Data

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医用生物力学 2019年第A1期34卷 93-94页

作者： Xiaoya Guo Don PGiddens David Molony Habib Samady Chun Yang Jie Zheng Mitsuaki matsumura Gary SMintz Akiko Maehara Liang Wang Dalin Tang Department of Mathematics Southeast UniversityNanjing210096China The Wallace H.Coulter Department of Biomedical Engineering Georgia Institute of TechnologyAtlantaGA30332USA Department of Medicine EmoryUniversitySchool of MedicineAtlantaGA30307USA Mathematical Sciences Department Worcester PolytechnicInstituteWorcesterMA01609USA Mallinckrodt Institute of Radiology Washington UniversitySt.LouisMO63110USA The Cardiovascular Research Foundation Columbia UniversityNew YorkNY10022USA School of BiologicalScience and Medical Engineering Southeast UniversityNanjing210096China

Background Current bottleneck of patient-specific coronary plaque model construction is the resolution of in vivo medical *** threshold of cap thickness of vulnerable coronary plaques is 65 microns,while the resolution of in vivo coronary intravascular ultrasound(IVUS)images is 150-200 microns,which is not enough to identify vulnerable plaques with thin caps and construct accurate biomechanical plaque *** coherence tomography(OCT)with a 15-20μm resolution has the capacity to identify thin fibrous *** and OCT images could complement each other and provide for more accurate plaque morphology,especially,fibrous cap thickness measurements.A modeling approach combining IVUS and OCT was introduced in our previous publication for cap thickness quantification and more accurate cap stress/strain *** this paper,patient baseline and follow-up IVUS and OCT data were acquired and multimodality image-based Fluidstructure interaction(FSI)models combining 3D IVUS,OCT,angiography were constructed to better quantify human coronary atherosclerotic plaque morphology and plaque stress/strain conditions and investigate the relationship of plaque vulnerability and morphological and mechanical *** Baseline and 10-Month follow-up in vivo IVUS and OCT coronary plaque data were acquired from one patient with informed consent ***-registration and segmentation of baseline and follow-up IVUS and OCT images were performed for modeling *** and follow-up 3D FSI models based on IVUS and OCT were constructed to simulate the mechanical factors which integrating plaque morphology were employed to predict plaque *** 3D models were solved by ADINA(ADINA R&D,Watertown,MA,USA).The quantitative indices of cap thickness,lipid percentage were classified according to histological literatures and denoted as Cap Index and Lipid *** Index,Lipid Index and Morphological Plaque Vulnerability Index(MPVI)were chosen to quantify plaq

关键词： coronary plaque OCT IVUS vulnerability patient-specific FSI model

Cryptogenic cirrhosis in the region where obesity is not prevalent

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World Journal of Gastroenterology 2006年第13期12卷 2080-2085页

作者： Hideyuki Kojima Shinya Sakurai Masahiko matsumura Norie Umemoto Masahito Uemura Hiroyo Morimoto Yasuhiro Tamagawa Hiroshi Fukui Third Department of Internal Medicine Nara Medical University 840 Shijo-cho Kashihara-shiNara 634-8522Japan Department of General Medicine and Clinical Investigation Nara Medical University 840 Shijo-cho Kashihara-shiNara 634-8522Japan Department of Internal Medicine Kokuho Central Hospital 404-1 Miyako TawaramotochoNara 636-0302Japan

AIM： Recent studies have demonstrated that obesity is the common feature of cryptogenic cirrhosis （CC） and non-alcoholic steatohepatitis. However, there is little information on CC in the region where obesity is not prevalent, METHODS： The clinical features, and the liver-related morbidity and mortality of CC were analyzed in Japan where the prevalence of obesity is low. Among 652 cirrhotic patients, we identified 29 patients （4.4%） with CC. Of these, 24 CC patients who were followed up for more than 6 months were compared in a case-control study with age-, sex-, and Child-Pugh score-matched controls having cirrhosis of viral etiology. RESULTS： Obesity （BMI≥25 kg/m^2）, diabetes mellitus, and hypertriglyceridemia were more frequent, and the visceral fat area was larger in the CC patients than in the controls. The indices of insulin resistance were higher and the serum aminotransferase levels were lower in the CC patients than in the controls. Logistic regression analysis identified the elevated hemoglobin A1c, BMI ≥ 25 kg/m^2, and normal aminotransferase levels as independent predictors of CC. Kaplan-Meier analysis demonstrated lower occurrence of hepatocellular carcinoma and higher survival rate in the CC than in the controls in contrast to the similar cumulatlve probability of liverrelated morbidity between those ***： CC more frequently presents with the clinical features suggestive of non-alcoholic steatohepatitis compared with controls even in the region where obesity is not prevalent. The lower occurrence of hepatocellular carcinoma and higher survival rate may indicate an indolent clinical course in CC as compared with viral cirrhosis.

关键词： Ke Cryptogenic cirrhosis Viral cirrhosis Nonalcoholic steatohepatitis Hepatocellular carcinoma Case-control study

Effects of flooding on arbuscular mycorrhizal colonization and root-nodule formation in different roots of soybeans

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Agricultural Sciences 2013年第12期4卷 673-677页

作者： Rintaro Hattori Atsushi matsumura Kenji Yamawaki Arata Tarui Hiroyuki Daimon Graduate School of Life and Environmental Sciences Osaka Prefecture University Osaka Japan

In several countries in monsoon Asia, soybean crops are cultivated in upland fields converted from paddies. In such fields, excess soil water often induces extensive damage followed by lower nutrient uptake by this crop. In this study, the effects of flooding during the early growth stage of pot-grown soybeans on arbuscular mycorrhizal (AM) colonization and root nodule formation were investigated. Twenty days after sowing cv. Fukuyutaka, half of the pots were flooded (flooding) and the other half were left unflooded (irrigation). The plants were sampled after 39 days of flooding. Typical morphological alterations to flooding were found, including an enlarged hypocotyl diameter and partial cracking of the surface tissues, and adventitious roots developed on the soil surface. The primary and lateral roots were shorter and the adventitious roots were longer in flooding than in irrigation. In flooding, the ratio of the aerenchyma area to the stele area was 82.5% in adventitious roots. The AM colonization ratio in flooding was significantly lower than in irrigation. The ratio in flooding was markedly low in the primary and lateral roots, but it was not necessarily low in the adventitious roots. Root nodules were formed on the adventitious roots but not on the primary and lateral roots, especially in flooding. These results showing different rates of AM colonization and root nodule formation between the two different types of roots improve the understanding of responses of soybeans grown in paddy-rotated upland fields.

关键词： Adventitious Root Aerenchyma Bradyrhizobium Root System Wet Injury

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加速器屏蔽体中氚的提取和比活度测量

原子能科学技术 2008年第5期42卷 465-469页

作者：王庆斌王芊 K. Masumoto K. Bessho H. matsumura T. Miura T. Shibata 中国科学院高能物理研究所北京100049 湖南农业科学院原子能利用研究所湖南长沙410001 High Energy Accelerator Research Organization (KEK) Tsukuba 305-0801 Japan

使用红外炉发展了一种从活化混凝土中提取氚的方法。通过研究氚的提取效率与加热温度、加热时间的关系,获得了氚的提取优化条件为在800℃下加热30 min,Ar气流量设置为200 mL/min。氚由两个冷凝管收集,然后装到1个小玻璃瓶中,与液体闪烁... 详细信息

使用红外炉发展了一种从活化混凝土中提取氚的方法。通过研究氚的提取效率与加热温度、加热时间的关系,获得了氚的提取优化条件为在800℃下加热30 min,Ar气流量设置为200 mL/min。氚由两个冷凝管收集,然后装到1个小玻璃瓶中,与液体闪烁体混合,使用液体闪烁计数器计数。使用这种方法提取氚只需55 min。相对于使用电子炉提取氚的方法,氚的提取效率可达到100%。收集了两个加速器屏蔽体中的混凝土样品,测量了样品中的γ射线核素和氚的放射性比活度。结果显示,氚的比活度与152Eu和60Co的比活度有很强的相关性。可得出结论:氚主要产生于热中子俘获反应6Li(n,α)3H。因而,可使用60Co的放射性比活度简单估计活化的混凝土样品中氚的放射性比活度。

关键词：混凝土样品氚红外炉液体闪烁计数器

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15岁的嫌疑人

Recent Advances in Iron Ore Sintering in NSSMC

2020年

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Recent Advances in Iron Ore Sintering in NSSMC