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Development of risky varices in alcoholic cirrhosis with a well-maintained nutritional status

World Journal of Hepatology 2015年第21期7卷 2358-2362页

作者： Hirayuki Enomoto Yoshiyuki Sakai Yoshinori Iwata Ryo Takata Nobuhiro Aizawa Naoto Ikeda Kunihiro Hasegawa Chikage Nakano Takashi Nishimura kazunori yoh Akio Ishii Tomoyuki Takashima Hiroki Nishikawa Hiroko Iijima Shuhei Nishiguchi Division of Hepatobiliary and Pancreatic Disease Department of Internal Medicine Hyogo College of Medicine

AIM: To compare the nutritional status between alcoholic compensated cirrhotic patients and hepatitis C virus(HCV)-related cirrhotic patients with portal ***: A total of 21 patients with compensated cirrhosis(14 with HCV-related cirrhosis and seven with alcoholic cirrhosis) who had risky esophageal varices were investigated. In addition to physical variables, including the body mass index, triceps skinfold thickness, and arm-muscle circumference, the nutritional status was also assessed using the levels of pre-albumin(pre-ALB), retinol-binding protein(RBP) and non-protein respiratory quotient(NPRQ) measured with an indirect ***: A general assessment for the nutritional status with physical examinations did not show a significant difference between HCV-related cirrhosis and alcoholic cirrhosis. However, the levels of pre-ALB and RBP in alcoholic compensated cirrhotic patients were significantly higher than those in HCV-related compensated cirrhotic patients. In addition, the frequency of having a normal nutritional status(NPRQ ≥ 0.85 and ALB value > 3.5 g/d L) in alcoholic compensated cirrhotic patients was significantly higher than that in HCV-related compensated cirrhotic ***: According to our small scale study, alcoholic compensated cirrhotic patients can develop severe portal hypertension even with a relatively well-maintained liver function and nutritional status compared with HCV-related cirrhosis.

关键词： Alcoholic liver cirrhosis Hepatitis C virus Rapid-

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