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LASER INDUCED FLUORESCENCE DETECTOR(LIF)FOR CAPILLARY ELECTROPHORESIS

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Chinese Chemical Letters 1996年第1期7卷 39-42页

作者： Ma, ms Han, HW Liu, GQ ACAD SINICA INST CHEMBEIJING 100080PEOPLES R CHINA

A highly sensitive laser induced fluorescence detector for capillary electrophoresis is described. With an argon laser at 488 nm for excitation, the emitted light was collected by an optical fiber and measured by it PMT. Various elements that affected the sensitivity of the detector were discussed in detail. The detection limit for fluorescein was 5.4 amole.

关键词： LIF)FOR CAPILLARY ELECTROPHORESIS LASER INDUCED FLUORESCENCE DETECTOR

Improved Soil Quality Prediction Model Using Deep Learning for Smart Agriculture Systems

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Computer Systems Science & Engineering 2023年第5期45卷 1545-1559页

作者： P.Sumathi V.V.Karthikeyan M.S.kavitha S.Karthik Department of Information Technology SNS College of EngineeringCoimbatoreTamilnaduIndia Department of Electrical and Electronics Engineering SNS College of TechnologyCoimbatoreTamilnaduIndia Department of Computer Science&Engineering SNS College of TechnologyCoimbatoreTamilnaduIndia

Soil is the major source of infinite lives on Earth and the quality of soil plays significant role on Agriculture practices all ***,the evaluation of soil quality is very important for determining the amount of nutrients that the soil require for proper *** present decade,the application of deep learning models in many fields of research has created greater *** increasing soil data availability of soil data there is a greater demand for the remotely avail open source model,leads to the incorporation of deep learning method to predict the soil *** that concern,this paper proposes a novel model called Improved Soil Quality Prediction Model using Deep Learning(ISQP-DL).The work considers the chemical,physical and biological factors of soil in particular area to estimate the soil ***,pH rating of soil samples has been collected from the soil testing laboratory from which the acidic range has been categorized through soil test and the same data has been taken as input to the Deep Neural Network Regression(DNNR)***,soil nutrient data has been given as second input to the DNNR *** utilizing this data set,the DNNR method is used to evaluate the fertility rate by which the soil quality has been *** training and testing,the model uses Deep Neural Network Regression(DNNR),by utilizing the *** results show that the proposed model is effective for SQP(Soil Quality Prediction Model)with efficient good fitting and generality is enhanced with input features with higher rate of classification *** results show that the proposed model achieves 96.7%of accuracy rate compared with existing models.

关键词： Soil quality classification accuracy deep learning neural network soil features training and testing

Cysticercosis of the eye

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International Journal of Ophthalmology(English edition) 2017年第8期10卷 1319-1324页

作者： Rebika Dhiman Saranya Devi kavitha Duraipandi Parijat Chandra Murugesan Vanathi Radhika Tandon Seema Sen Dr Rajendra Prasad Centre for Ophthalmic Sciences All India Institute of Medical Sciences New Delhi 110029 India

Cysticercosis is a preventable and eradicable cause of blindness endemic in the Indian subcontinent, South- East Asia and other developing countries. Ocular and orbital cysticercosis has varied presentations depending upon the site of involvement, number of lesion and the host immune response. In this article we present a review of the various clinical manifestations, diagnosis and management protocol for orbital and ocular cysticercosis. Owing to its varied presentation, cysticercosis may pose a diagnostic challenge to the health professionals. Early diagnosis and management can prevent the vision loss and optimize visual outcomes.

关键词： cysticercosis orbital cysticercosis ocular cysticercosis intracameral cysticercosis

Association of metabolic NCD risk factors with oral, breast and cervical precancers and cancers in India

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Family Medicine and Community Health 2019年第4期7卷 37-45页

作者： Ashwini Kedar Roopa Hariprasad Vipin Kumar kavitha Dhanasekaran Ravi Mehrotra Department of Clinical Oncology National Institute of Cancer Prevention and ResearchNoidaIndia

Objective To find an association between metabolic non-communicable disease(NCD)risk factors(high blood pressure(BP),high random blood sugar(RBS)and overweight/obesity)and oral,breast,cervical cancers/precancerous or potentially malignant *** This is an observational study using convenience *** participants were screened through opportunistic or population-based *** The study was conducted at a health promotion clinic(HPC)located in Northern India under the Indian Council of Medical *** is a screening clinic where screening is done for hypertension(HT),diabetes mellitus(DM),obesity,and oral,breast and cervical *** study was conducted between December 2016 and January *** The number of participants screened was 8352(6712 women and 1640 men).All consenting men and women above 18 years were *** participants were screened for oral cancer,DM,HT and *** women were also screened for breast and cervical *** screening was done for non-pregnant women 21 years and above with history of sexual *** Oral potentially malignant disease(OPMD)was the most prevalent,followed by breast cancer,oral cancer,cervical cancer and cervical *** RBS had a strong association with oral cancer(OR=2.29,95%CI 1.09 to 4.82,p=0.03)and breast cancer(OR=1.95,95%CI 1.01 to 3.76,p=0.05).High BP had a strong association with breast cancer(OR=2.50,95%CI 1.43 to 4.35,pms that NCD metabolic risk factors determine oral and breast *** NCD risk factors,current tobacco use was a strong determinant

关键词： cervical breast cancers

Epigenetic regulation−The guardian of cellular homeostasis and lineage commitment

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BIOCELL 2021年第3期45卷 501-515页

作者： kavitha GOVARTHANAN PIYUSH K UMAR GUPTA BINITA ZIPPORAHE REKHA GAHTORI SOUMYA PANDIT RAM PRASAD Department of Biotechnology Indian Institute of Technology MadrasChennai600036India Department of Life Sciences Sharda UniversityGreater NoidaUttar Pradesh201310India Department of Biotechnology Campus–BhimtalKumaun UniversityNainitalUttarakhand263136India Department of Botany Mahatma Gandhi Central UniversityMotihariBihar845401India

Stem cells constitute the source of cells that replenishes the worn out or damaged cells in our tissue and enable the tissue to carry out the destined ***-specific stem cells are compartmentalized in a niche,which keeps the stem cells under quiescent ***,understanding the molecular events driving the successful differentiation of stem cells into several lineages is essential for its better manipulation of human *** the developmental aspects of the cell,the cellular function is greatly dependent on the epigenomics signature that in turn governs the expression profile of the *** stable inheritance of the epigenome is crucial for the development,modulation,and maintenance of the cell and its complex tissue-specific *** evidence suggesting that stem cell chromatin comprises a specialized state in which self-renewing genes and its downstream lineage-specific genes are kept paralleled poised for ***,the epigenetic regulatory network and pathway dictate lineage commitment and *** mainly modifies the chromatin landscape to facilitate euchromatin and heterochromatin architecture,which in turn alters the accessibility of transcription factors to the gene *** methylation and histone marks are the two widely studied epigenetic modifications regulating the transcriptome profile of a specific *** in the epigenetic landscape lead to diseases or ***,we emphasize the prominence of the epigenetic network and its regulation in normal tissue functioning and in the diseased ***,we highlighted the emerging role of epigenetic modifiers in lineage differentiation and epigenetic markers as novel druggable targets for cancer therapy.

关键词： Epigenetics Chromatin Genome Methylation Inheritance Modulation

Direct costs of carcinoid syndrome diarrhea among adults in the United States

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World Journal of Gastroenterology 2019年第47期25卷 6857-6865页

作者： Arvind Dasari Vijay N Joish Raul Perez-Olle Samyukta Dharba kavitha Balaji Daniel M Halperin Department of Gastrointestinal Medical Oncology The University of Texas MD Anderson Cancer CenterHoustonTX 77030United States Lexicon Pharmaceuticals Inc.The WoodlandsTX 77381United States

BACKGROUND The burden of carcinoid syndrome(CS)among patients with neuroendocrine tumors is substantial and has been shown to result in increased healthcare resource use and *** incremental burden of CS diarrhea(CSD)is less well understood,particularly among working age adults who make up a large proportion of the population of patients with *** To estimate the direct medical costs of CSD to a self-insured employer in the United *** CS patients with and without CSD were identified in the IBM®MarketScan®Database,including the Medicare Supplemental Coordination of Benefits *** patients had≥1 medical claim for CS with continuous health plan enrollment for≥12 mo prior to their first CS diagnosis and for≥30 d after,no claims for acromegaly,and no clinical trial participation during the study period(2014-2016).Baseline demographic and clinical characteristics,including comorbidities and treatment,were analyzed using descriptive *** of healthcare resource use and costs were compared between patients with and without CSD,including Emergency Department(ED)visits,hospital admissions and length of stay,physician office visits,outpatient services,and prescription claims,using univariate and multivariate analyses to evaluate associations of CSD with healthcare resource use and costs,controlling for baseline *** Overall,6855 patients with CS were identified of which 4,043 were eligible for the analysis(1352 with CSD,2691 with CS only).Baseline demographic and clinical characteristics were similar between groups with the exception of age,underlying tumor type,and health insurance *** with CSD were older,had more comorbidities,and received more somatostatin analog therapy at *** with CSD required greater use of healthcare resources and incurred higher costs than their peers without CSD,including hospitalizations(44%vs 25%)and ED visits(55%vs 31%).The total adjusted annual healthcare costs

关键词： Carcinoid syndrome Carcinoid syndrome diarrhea Healthcare costs Neuroendocrine tumors

An Efficient On-Demand Virtual Machine Migration in Cloud Using Common Deployment Model

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Computer Systems Science & Engineering 2022年第7期42卷 245-256页

作者： C.Saravanakumar R.Priscilla B.Prabha A.kavitha M.Prakash C.Arun Department of Information Technology St.Joseph’s Institute of TechnologyChennai600119India Department of Information Technology Loyola-ICAM College of Engineering and TechnologyChennai600034India Department of Electronics and Communication Engineering M.Kumarasamy College of EngineeringKarur639113India Data Science and Analytics Center Karpagam College of EngineeringCoimbatore641032India Department of Electronics and Communication Engineering R.M.K College of Engineering and TechnologyChennai601206India

Cloud Computing provides various services to the customer in aﬂex-ible and reliable *** Machines(VM)are created from physical resources of the data center for handling huge number of requests as a *** tasks are executed in the VM at the data center which needs excess hosts for satis-fying the customer *** VM migration solves this problem by migrating the VM from one host to another host and makes the resources available at any *** process is carried out based on various algorithms which follow a pre-deﬁned capacity of source VM leads to the capacity issue at the destination *** proposed VM migration technique performs the migration process based on the request of the requesting host *** technique can perform in three ways namely single VM migration,Multiple VM migration and Cluster VM *** Deployment Manager(CDM)is used to support through negotiation that happens across the source host and destination host for providing the high quality service to their *** VM migration requests are handled with an exposure of the source host *** proposed analysis also uses the retired instructions with execution by the hypervisor to achieve high *** objective of the proposed technique is to perform a VM migration process based on the prior knowledge of the resource availability in the target VM.

关键词： Cloud computing virtualization hypervisor VMmigration virtual machine

Rheological Behaviors of Polymer Melts and Concentrated Solutions Part VI: Comparison of the Material Functions with Yielding and Thinning for Polymeric Suspensions with Their Experimental Values

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Journal of Materials Science & Technology 1999年第3期15卷 251-252,523-262页

作者： Song, ms Zhou, W Hu, GXX Hu, LJ Beijing Univ Chem Technol Res Inst Polymer Mat Beijing 100029 Peoples R China Harbin Inst Technol Dept Appl Chem Harbin 150001 Peoples R China

The memory function and elastic modulus were introduced into the O-W-F type of constitutive equations with the Cauchy-Green and Finger tensors for simple fluid, and then the concrete constitutive equation and material function for polymeric suspensions in the different flow fields were formulated: 1) Viscosity and first normal-stress difference coefficient in the shear flow field; 2) Tensile viscosity at the uni-axial elongation flow field; and 3) Dynamic viscosity and modulus in the dynamic field. Then the dependence of the material function on the deformation rate and weight fraction of fillers was discussed, and the shear flow curves with four characteristic regions ( I-low shear rate plateau region, II- apparent yielding region, ill-intermediate rate plateau region, and lV-shear thinning region.) were explained theoretically. Finally, it was verified by a number of experimental values for the rheological suspensions and the viscoelastic and mechanical behaviors can be predicted by the molecular theory of non-linear viscoelasticity for polymeric suspension;.

关键词： Th Comparison of the Material Functions with Yielding and Thinning for Polymeric Suspensions with Their Experimental Values Rheological Behaviors of Polymer Melts and Concentrated Solutions Part VI

Clinical profile of brucellosis from a tertiary care center in southern India

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Asian Pacific Journal of Tropical Medicine 2011年第5期4卷 397-400页

作者： Vishwanath Sathyanarayanan Abdul Razak kavitha Saravu Shastry Barkur Ananthakrishna Mukhyprana Prabhu M Vandana KE Department of Internal Medicine Kasturba Medical CollegeManipal UniversityKarnatakaIndia Department of Microbiology Kasturba Medical CollegeManipal UniversityKarnatakaIndia

Objective:To highlight the spectrum of clinical manifestations,labs,complications,treatment and outcome of ***:Retrospective study was conducted in Kasturba Medical College,Manipal University,Karnataka,India which included 68 confirmed cases of brucellosis from January 2006- April *** of brucellosis was made by culturing the sera/body fluids by standard BACTEC method(or) by testing the sera for Brucella agglutinins using the standard agglutination test(SAT).A titer of 1:320 or more was considered as *** 16 was used for statistical analysis and Microsoft Excel for graphical ***:Of the 68 patients,46(68%) were male and 22(32%) were female patients with age distribution of 9-75 *** four(64.7%) had history of contact with unpasteurized dairy products or infected *** included fever(68,100%),myalgia(21,31%),musculoskeletal symptoms (23,34%),headache(16,24%),gastrointestinal symptoms(19,28%) and altered sensorium(3, 4%).Co-morbidities and associations included HIV positivity(2,3%),type 2 diabetes mellitus (13,19%),steroid therapy(3,4%) and HBsAg positivity(8,12%).Ten(15%) patients had cervical lymphadenopathy,4(6%) had splenic enlargement,6(7%) had hepatomegaly,19(28%) had hepatosplenomegaly and 2(3%) got meningeal *** was observed in 39(57.3%) cases,high erythrocyte sedimentation rate(ESR) was present in 55(80.8%) cases,leucocytosis in 10(14.7%),leucopenia in 10(14.7%),thrombocytopenia in 23(33.82%) and thrombocytosis in 2(2.94%) ***:In countries like India,where brucellosis and tuberculosis are endemic;rapid,sensitive and highly specific diagnostic methods are required to make early diagnosis and prevent resistance as there is an overlap in therapy.

关键词： Brucella South India BACTEC Standard agglutination test