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Which characteristics are associated with changes in medication status for lower urinary tract symptoms among patients with prostate cancer receiving external beam radiotherapy?

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CURRENT UROLOGY 2024年第2期18卷 122-127页

作者： Kyoda, Yuki Hashimoto, Kohei Takahashi, Atsushi Maehana, Takeshi Tachikawa, Kimihito Muranaka, Takashi kato, shuichi Kurisu, Tomoyo Fukuta, Fumimasa Kirisawa, Takahiro Okada, Manabu Kobayashi, Ko Tanaka, Toshiaki Hinotsu, Shiro Masumori, Naoya Sapporo Med Univ Sch Med Dept Urol S-1W-16Chuo Ku Sapporo 0608543 Japan Hakodate Goryoukaku Hosp Dept Urol Hakodate Japan Muroran City Gen Hosp Dept Urol Muroran Japan NTT East Sapporo Hosp Dept Urol Sapporo Japan Sunagawa City Med Ctr Dept Urol Sunagawa Japan Oji Gen Hosp Dept Urol Tomakomai Japan Steel Mem Muroran Hosp Dept Urol Muroran Japan Obihiro Kyokai Hosp Dept Urol Obihiro Japan Sapporo Med Univ Sch Med Dept Med Stat Sapporo Japan

BackgroundWe clarified the predictive factors for changes in the status of medications for lower urinary tract symptoms (LUTS) 2 years after local radiotherapy for nonmetastatic prostate cancer. Materials and methodsWe retrospectively included patients who underwent local external radiotherapy for nonmetastatic prostate cancer in 8 institutions between April 2001 and March 2016. Patients were divided into the medication and no-medication group based on the use of drugs for LUTS before radiotherapy. We defined improvement of LUTS as when the patient did not require medication for LUTS at 24 months after radiotherapy in the medication group and as deterioration when medication was required in the no-medication group. Logistic regression analysis was used to evaluate predictive factors for changes in medication status. ResultsAltogether, 505 patients were divided into a no-medication group (n = 352) and a medication group (n = 153). The number of patients with deterioration and improvement in LUTS was 49 (14%) and 36 (23%), respectively. In the multivariate analysis, the predictive variables for deterioration were the International Prostate Symptom Score (>= 8; odds ratio [OR], 2.21; p = 0.014) and the biopsy Gleason score (= 50%; OR, 2.530; p = 0.027) in the medication group. ConclusionsThese predictive factors for changes in the status of medications for LUTS at 2 years after external radiotherapy may help determine the definitive therapy for nonmetastatic prostate cancer.

关键词： Prostate cancer Radiotherapy Lower urinary tract symptoms Medications ANDROGEN DEPRIVATION THERAPY QUALITY-OF-LIFE RADIATION VOLUME MEN TOXICITY RELIEF

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Who needs further evaluations to diagnose upper urinary tract urothelial cancers among patients with abnormal findings by enhanced CT?

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Asian Journal of Urology 2016年第1期3卷 44-48页

作者： Akio Takayanagi Atsushi Takahashi Fumimasa Fukuta Manabu Okada Masahiro Matsuki Shunsuke Sato Teruhisa Uehara shuichi kato Yoshio Takagi Department of Urology Hakodate Goryoukaku HospitalHakodateHokkaidoJapan Department of Urology Sapporo Medical University School of MedicineSapporoHokkaidoJapan

Objective:We evaluated who would need further evaluations such as retrograde pyelography(RP)and/or ureteroscopy to diagnose upper urinary tract urothelial cancers(UUTUCs)when abnormal findings for the upper urinary tract(UUT)were detected by enhanced computed tomography(CT).Methods:We retrospectively analyzed 125 patients who underwent enhanced CT for various reasons and had abnormal findings for the *** whose tumors were suspected to be of extraureteral origin were *** patients received RP and/or ureteroscopy to evaluate the ***:The median age of the 125 patients was 70 years and gross hematuria(26.4%)was the most frequently observed ***,ureteroscopy and both were performed for 121,59 and 55 patients,*** revealed tumor-like lesions in 58 patients and the other patients had non-tumor-like *** were found in 43(34.4%)of the 125 *** of them had tumor-like lesions on *** 58 patients who had tumor-like lesions on CT,univariate and multivariate analyses revealed that tumor diameter and tumor enhancement were significant predictive factors for *** curve analysis of enhanced CT to diagnose UUTUCs revealed that a tumor diameter of 18 mm was the best cutoff *** sensitivity,specificity and accuracy were 90.0%,98.8% and 92.7% for RP and 95.5%,100% and 97.1%for ureteroscopy,*** of them had high sensitivity,specificity and ***:We should decide to evaluate the UUT according to the tumor diameter on enhanced *** we evaluate the UUT in patients with tumor diameters of less than 20 mm,ureteroscopy is recommended.

关键词： Upper urinary tract urothelial cancers Enhanced CT Ureteroscopy Retrograde pyelography

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New method of local adjuvant therapy with bicarbonate Ringer’s solution for tumoral calcinosis: A case report

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World Journal of Orthopedics 2024年第3期15卷 302-309页

作者： Takashi Noguchi Akio Sakamoto Kensaku Kakehi shuichi Matsuda Department of Orthopaedic Surgery Graduate School of MedicineKyoto UniversityKyoto 606-8507Japan

BACKGROUND Tumoral calcinosis is a condition characterized by deposits of calcium phosphate crystals in extra-articular soft tissues,occurring in hemodialysis *** phosphate crystals are mainly composed of hydroxyapatite,which is highly infilt-rative to tissues,thus making complete resection *** adjuvant method to remove or resolve the residual crystals during the operation is *** SUMMARY A bicarbonate Ringer’s solution with bicarbonate ions(28 mEq/L)was used as the *** resecting calcium phosphate deposits of tumoral calcinosis as much as possible,while filling with the solution,residual calcium phosphate deposits at the pseudocyst wall can be gently scraped by fingers or gauze in the operative field.A 49-year-old female undergoing hemodialysis for 15 years had swelling with calcium deposition for 2 years in the shoulders,bilateral hip joints,and the right foot.A shoulder lesion was resected,but the calcification remained and early re-deposition was *** the difficulty of a complete rection,we devised a bicarbonate dissolution method and excised the foot *** resection of the calcified material,the residual calcified material was washed away with bicarbonate Ringer’s *** The bicarbonate dissolution method is a new,simple,and effective treatment for tumoral calcinosis in hemodialysis patients.

关键词： Tumoral calcinosis Adjuvant therapy Bicarbonate Ringer’s solution Surgery Case report

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Flow Rate Measurement of Gravity Infusion Set and Functional Evaluation of Drop Counter: A Pilot Study

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Journal of Biomedical Science and Engineering 2024年第7期17卷 129-135页

作者： Rina Sakai shuichi Tanaka Kaya Murakami Tomomi Mizuhashi Kazuhiro Yoshida Masanobu Ujihira Department of Medical Engineering and Technology Kitasato University School of Allied Health Sciences Sagamihara Japan Faculty of Medical Engineering Gunma University of Health and Welfare Maebashi Japan Kitasato University Graduate School of Medical Sciences Sagamihara Japan

Developing a novel drop counter by introducing the Internet of Things concept has been vigorously conducted in recent years. Understanding the newly introduced drop counter’s flow rate control accuracy and flow rate count feature is essential for improving safety in infusion management. This study aimed to verify if the new drop counters could secure accurate flow rate and drip count by conducting actual flow rate measurements using gravimetry and functional evaluation. A drop counter was attached to each drip chamber of the infusion set, and an IV drip was conducted at the 100 ml/h flow rate. The weight of discharged physiological saline was measured to plot trumpet curves. Next, three different types of drop counters were evaluated to determine if they maintained drip count accuracy according to the changes in their position angles. The flow rate errors in all conditions indicated trumpet-like curves, exhibiting an overall error range within ±10% in all observation windows. Although every drop counter successfully detected and measured dripping, it was challenging in some counters to detect dripping when the drip chamber was tilted. In comparing adult and pediatric IV sets, the adult IV set was found to be less likely to detect dripping in the angled position. No significant differences in results were confirmed between high and low flow rates, suggesting that the drop count function would not be affected by the flow rate in the ranges of typical infusion practices. Doppler sensors have a wide range of measurements and high sensitivity;the dripping was detected successfully even when the drip chamber was tilted, probably due to the advantages of these sensors. In contrast, miscounts occurred in those equipped with infrared sensors, which could not detect light intensity changes in tilted positions. Understanding the tendencies in flow rate errors in infusion can be valuable information for infusion management.

关键词： Gravity Infusion Set Drop Counter IV Fluids Flow Rate Trumpet Curves

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Japanese Perspectives on Nutrition for New Millenium

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Biomedical and Environmental Sciences 2001年第1期14卷 82-86页

作者： shuichi KIMURA ShowaWomen’sUniversity ILSI1_7TaishdoSetaguyaku

The Japanese are the longest living people in the world. According to Japan's Ministry of Health and Welfare, the average life expectancy at birth for male born in 1997 was 77.10 years, and the figure for female was 83.99 years.　　Our country is ranked first in the Healthy Life Expectancy as shown in Table 1. The total Disability Adjusted Life Expectancy (DALE) is 74.5 years.

关键词： life expectancy the world

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Dissipative structure for symmetric hyperbolic systems with memory

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Science China Mathematics 2018年第11期61卷 2053-2064页

作者： shuichi Kawashima Shogo Taniue Faculty of Mathematics Kyushu University Graduate School of Mathematics Kyushu University

We study symmetric hyperbolic systems with memory-type dissipation and investigate their dissipative *** treat two cases:memory-type diffusion and memory-type relaxation,and observe that the dissipative structures of these two cases are essentially ***,we show that the dissipative structure of the system with memory-type diffusion is of the standard type,while that of the system with memory-type relaxation is of the regularity-loss type.

关键词： hyperbolic systems memory-type dissipation dissipative structure

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Experimental Study on Load Characteristics in a Floating Type Pendulum Wave Energy Converter

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Journal of Thermal Science 2014年第5期23卷 465-471页

作者： Tengen Murakami Yasutaka Imai shuichi Nagata Institute of Ocean Energy Saga University

A floating type pendulum wave energy converter(FPWEC) with a rotary vane pump as the power take-off system was proposed by Watabe et *** *** showed that this device had high energy conversion *** the previous research,the authors conducted 2D wave tank tests in regular waves to evaluate the generating efficiency of FPWEC with a power take-off system composed of pulleys,belts and a *** a result,the influence of the electrical load on the generating efficiency was ***,the load characteristics of FPWEC are pursued experimentally by using the servo motors to change the damping coefficient in this *** a later part of this paper,the motions of the model with the servo motors are compared with that of the case with the same power take-off system as the previous *** the above experiment,it may be concluded that the maximum primary conversion efficiency is achieved as high as 98%at the optimal load.

关键词： pendulum wave energy converter floating type load characteristics primary conversion efficiency

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Electron Temperature Measurement by Floating Probe Method Using AC Voltage

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Plasma Science and Technology 2016年第11期18卷 1089-1094页

作者： Satoshi NODOMI shuichi SATO Mikio OHUCHI Department of Electrical and Electronic Engineering Tokyo Denki University

This study presents a novel floating probe method to measure electron temperatures using a hollow cathode-type discharge tube. The proposed method detects a shift in the floating potential when an AC voltage is applied to a probe through an intermediary blocking capacitor. The shift in the floating potential is described as a function of the electron temperature and the applied AC voltage. The floating probe method is simpler than the Langmuir probe method because it does not require the measurement of volt-ampere characteristics. As the input AC voltage increases, the electron temperature converges. The electron temperature measured using the floating probe method with an applied sinusoidal voltage shows a value close to the first （tail） electron temperature in the range of the floating potential.

关键词： electrostatic probe Langmuir probe floating potential electron temperature sheath

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Nonlinear Magnetic Response of Superconducting Flux Arrays with Random Pinning

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Chinese Physics Letters 1997年第3期14卷 217-220页

作者： NI Jun GU Bing-lin shuichi Iwata Department of Physics Tsinghua UniversityBeijing 100084 Research into Artifacts Center for EngineeringThe University of TokyoKamaba 4-6-1Meguro-kuTokyo 153Japan

The static nonlinear magnetic response of randomly pinned flux-line lattice in a type-Ⅱ super-conductor has been investigated using variational replica-symmetry-broken method.A peak in the curve of susceptibility as a function of external magnetic field is *** the magnetic field is low,there is a softening in the susceptibility as an effect of pinning potential with nonzero correlation *** some critical magnetic field,the softening changes into *** reaching the maximum in hardening,the susceptibility decreases to its value of piire states with the increase of magnetic field.

关键词： method. field. susceptibility

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论唐代皇帝让位时的改元——玄宗缘何于十二月改元开元

唐史论丛

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唐史论丛 2024年第1期 31-46页

作者： [日]金子修一王坤(译) 日本国学院大学西安电子科技大学外国语学院

引言2019年日本天皇退位并随之改元,从而引发了日本国民对于皇位继承方式及年号的极大关心。笔者也承蒙加藤阳子女士约稿,发表了《中国皇帝的让位与元号[1]》一文[2],收录于加藤女士编著的《天皇是如何继承的——天皇的身体与皇位继承... 详细信息

引言2019年日本天皇退位并随之改元,从而引发了日本国民对于皇位继承方式及年号的极大关心。笔者也承蒙加藤阳子女士约稿,发表了《中国皇帝的让位与元号[1]》一文[2],收录于加藤女士编著的《天皇是如何继承的——天皇的身体与皇位继承》一书中。不仅是在古代中国,大凡世界上的君主国在先王(君主)死后都会立新王,而像日本“院政时期”[3]那样,以先皇让位的形式为惯例的反而是例外。

关键词：皇位继承日本天皇君主国加藤改元

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