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On the Ladder

小学生时代（大嘴英语） 2021年第3期 40-41页

作者： kathleen Marcotte 不详

美好的童年怎么能少得了一间可爱的树屋呢?和好朋友一起,在珍藏着很多秘密的树屋里玩耍,那会是怎样的一种快乐呀!

关键词： Ladder 快乐 On

High-Throughput Screening Using Fourier-Transform Infrared Imaging

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Engineering 2015年第2期1卷 234-242页

作者： Erdem Sasmaz kathleen Mingle Jochen Lauterbach SmartState Center for Strategic Approaches to the Generation of Electricity (SAGE) Department of Chemical Engineering University of South Carolina

Efficient parallel screening of combinatorial libraries is one of the most challenging aspects of the high- throughput （HT） heterogeneous catalysis workflow. Today, a number of methods have been used in HT catalyst studies, including various optical, mass-spectrometry, and gas- chromatography techniques. Of these, rapid-scanning Fourier-transform infrared （FTIR） imaging is one of the fastest and most versatile screening techniques. Here, the new design of the 16-channel HT reactor is presented and test results for its accuracy and reproducibility are shown. The performance of the system was evaluated through the oxidation of CO over commercial Pd/AI203 and cobalt oxide nanoparticles synthesized with different reducer-reductant molar ratios, surfactant types, metal and surfactant concentrations, synthesis temperatures, and ramp rates.

关键词： high-throughput FTIR imaging screening cobalt oxide CO oxidation

Biomass residue to carbon dioxide removal:quantifying the global impact of biochar

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Biochar 2023年第1期5卷 1131-1147页

作者： David Lefebvre Samer Fawzy Camila A.Aquije Ahmed I.Osman kathleen T.Draper Thomas A.Trabold University of British Columbia VancouverBC V6T 1Z4Canada School of Chemistry and Chemical Engineering Queen’s UniversityBelfast BT95AGNorthern Ireland Trinity Biocarbon Masdar CityP.O.Box 135098Abu DhabiUAE International Biochar Initiative(IBI) LongmontCO 80501USA Golisano Institute for Sustainability Rochester Institute of TechnologyRochesterNY 14623USA

The Climate Change Conference of Parties(COP)21 in December 2015 established Nationally Determined Contributions toward reduction of greenhouse gas *** the years since COP21,it has become increasingly evident that carbon dioxide removal(CDR)technologies must be deployed immediately to stabilize concentration of atmospheric greenhouse gases and avoid major climate change *** is a carbon-rich material formed by high-temperature conversion of biomass under reduced oxygen conditions,and its production is one of few established CDR methods that can be deployed at a scale large enough to counteract effects of climate change within the next *** we provide a generalized framework for quantifying the potential contribution biochar can make toward achieving national carbon emissions reduction goals,assuming use of only sustainably supplied biomass,i.e.,residues from existing agricultural,livestock,forestry and wastewater treatment *** results illustrate the significant role biochar can play in world-wide CDR strategies,with carbon dioxide removal potential of 6.23±0.24%of total GHG emissions in the 155 countries covered based on 2020 data over a 100-year timeframe,and more than 10%of national emissions in 28 *** regions of high biochar carbon dioxide removal potential relative to national emissions were identified in South America,northwestern Africa and eastern Europe.

关键词： Pyrolysis Biochar Waste biomass Carbon sequestration Negative emissions technologies(NETs) Nationally Determined Contributions(NDCs)

A Zebrafish Model of 5q-Syndrome Using CRISPR/Cas9 Targeting RPS14 Reveals a p53-Independent and p53-Dependent Mechanism of Erythroid Failure

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Journal of Genetics and Genomics 2016年第5期43卷 307-318页

作者： Jason Ear Jessica Hsueh Melinda Nguyen QingHua Zhang Victoria Sung Rajesh Chopra kathleen M.Sakamoto Shuo Lin Department of Molecular Cell and Developmental Biology University of California Los Angeles Los Angeles CA 90095 USA Celgene Corporation San Francisco 94158 USA Celgene Corporation Summit NJ 07901 USA Division of Hematology/Oncology Department of Pediatrics Stanford University School of Medicine Stanford CA 94304 USA

5q-syndrome is a distinct form of myelodysplastic syndrome（MDS） where a deletion on chromosome 5 is the underlying *** is characterized by bone marrow failures,including macrocytic *** mapping and studies using various models support the notion that ribosomal protein S14（RPS14） is the candidate gene for the erythroid *** disruption of RPS14 causes an increase in p53 activity and p53-mediated apoptosis,similar to what is observed with other ribosomal ***,due to the higher risk for cancer development in patients with ribosome deficiency,targeting the p53 pathway is not a viable treatment *** better understand the pathology of RPS14 deficiency in 5q-deletion,we generated a zebrafish model harboring a mutation in the RPS14 *** model mirrors the anemic phenotype seen in ***,the anemia is due to a late-stage erythropoietic defect,where the erythropoietic defect is initially p53-independent and then becomes ***,we demonstrate the versatility of this model to test various pharmacological agents,such as RAP-011,L-leucine,and dexamethasone in order to identify molecules that can reverse the anemic phenotype.

关键词： 5q-syndrome RPS14 Ribosomopathy Myelodysplastic syndrome

Association of subcutaneous testosterone pellet therapy with developing secondary polycythemia

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Asian Journal of Andrology 2018年第2期20卷 195-199页

作者： Katherine Lang Rotker Michael Alavian Bethany Nelson Grayson L Baird Martin M Miner Mark Sigman kathleen Hwang Division of Urology Brown University Providence RI 02903 USA Department of Biostatistics Lifespan Healthcare System Providence RI 02903 USA

A variety of methods for testosterone replacement therapy （TRT） exist, and the major potential risks of TRT have been well established. The risk of developing polycythemia secondary to exogenous testosterone （T） has been reported to range from 0.4% to 40%. Implantable T pellets have been used since 1972, and secondary polycythemia has been reported to be as low as 0.4% with this administration modality. However, our experience has suggested a higher rate. We conducted an institutional review board-approved, single-institution, retrospective chart review （2009-2013） to determine the rate of secondary polycythemia in 228 men treated with subcutaneously implanted testosterone pellets. Kaplan-Meyer failure curves were used to estimate time until the development of polycythemia （hematocrit 〉50%）. The mean number of pellets administered was 12 （range： 6-16）. The mean follow-up was 566 days. The median time to development of polycythemia whereby 50% of patients developed polycythemia was 50 months. The estimated rate of polycythemia at 6 months was 10.4%, 12 months was 17.3%, and 24 months was 30.2%. We concluded that the incidence of secondary polycythemia while on T pellet therapy may be higher than previously established.

关键词： hypogonadism pellet polycythemia testosterone

Can rarefaction be used to estimate song repertoire size in birds？

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Current Zoology 2011年第3期57卷 300-306页

作者： kathleen R. PESHEK Daniel T. BLUMSTEIN The Rocky Mountain Biological Laboratory Box 519 Crested Butte CO 81224 USA Department of Ecology and Evolutionary Biology University of California Los Angeles CA 90095-1606 USA

Song repertoire size is the number of distinct syllables, phrases, or song types produced by an individual or population. Repertoire size estimation is particularly difficult for species that produce highly variable songs and those that produce many song types. Estimating repertoire size is important for ecological and evolutionary studies of speciation, studies of sexual selection, as well as studies of how species may adapt their songs to various acoustic environments. There are several methods to estimate repertoire size, however prior studies discovered that all but a full numerical count of song types might have substantial inaccuracies associated with them. We evaluated a somewhat novel approach to estimate repertoire size--rarefaction; a technique ecologists use to measure species diversity on individual and population levels. Using the syllables within American robins＇ Turdus migratorius repertoire, we compared the most commonly used techniques of estimating repertoires to the results of a rarefaction analysis. American robins have elaborate and unique songs with few syllables shared between individuals, and there is no evidence that robins mimic their neighbors. Thus, they are an ideal system in which to compare techniques. We found that the rarefaction technique results resembled that of the numerical count, and were better than two alternative methods （behavioral accumulation curves, and capture-recapture） to estimate syllable repertoire size. Future estimates of repertoire size, particularly in vocally complex species, may benefit from using rarefaction techniques when numerical counts are unable to be performed [Current Zoology 57 （3）： 300-306, 2011].

关键词： Behavioral accumulation curve Bioacoustics Capture-recapture Numerical count Rarefaction Song repertoire size

Exploring If an Embedded Study-away Experience Impacts Change in Undergraduate Students＇ Intercultural Competence and Awareness

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Management Studies 2015年第2期3卷 67-76页

作者： kathleen Garrett Rust Elmhurst College Elmhurst USA

This research considers the value of an embedded intercultural experience and if it is critical to the development of intercultural knowledge and awareness. Undergraduate students＇ obtainment of intercultural knowledge and awareness were tested under three conditions：（1） students in a course intentionally designed to develop intercultural self-awareness and intercultural related critical thinking skills （no travel component）; （2） students in a course intentionally designed to develop intercultural self-awareness and intercultural related critical thinking skills （including an embedded one-week travel component）; and （3） students in a course not specifically designed to develop intercultural self-awareness and intercultural related critical thinking skills （including an embedded one-week travel component）. The initial findings suggest that, on average, students who enrolled in courses with the intention of building intercultural competence experienced a positive change in intercultural learning, while students in the course not specifically designed to develop intercultural learning, on average, experienced no change in intercultural learning as measured by the intercultural development inventory （IDI）. The results support other findings indicating that immersion in another culture only may not create an opportunity for intercultural learning. This finding reinforces the need for intentional learning opportunities before, during, and after a study-away immersion. However, the omission of an embedded experiential learning opportunity may not lessen intercultural learning.

关键词： cultural development study-abroad intercultural competence

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Space Mountains

China Weekly 2023年第9期 60-61页

作者： kathleen Naday 不详

Get spaced out on a visit to Ulanhada Volcano Geopark,where you can admire the alchemy and brimstone in an as yet undeveloped tourist *** space-bro Elon Musk fails in his stated ambition to get to Mars,he could perhaps find an alternative in the otherworldly landscape of Ulanhada Volcano *** even provide the *** Harry Potter cloaks,though magic might not work as well as a *** have those too,in the form of gigantic freworks on sale to"recreate an eruption."

关键词： landscape eruption Mountains

Nanjing,Fujian:Heights of the Tulou

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China Weekly 2022年第2期 60-61页

作者： kathleen Naday 不详

It was a raceagainst time to get to my guesthouse in the small Hakka village of Taxia,some 160 kilometers west,of Xiamen,Fujian *** rain had been pounding all day,and the driver was *** charged along the narrow stone ... 详细信息

关键词： Province. Xiamen narrow