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Tissue culture tools for selenium hyperaccumulator Neptunia amplexicaulis for development in phytoextraction

Natural Products and Bioprospecting 2022年第1期12卷 409-417页

作者： Billy O’Donohue Jayeni Hiti-Bandaralage Madeleine Gleeson Chris O’Brien Maggie-Anne Harvey Antony van der Ent katherine pinto irish Neena Mitter Alice Hayward Centre for Horticultural Science Queensland Alliance for Agriculture and Food InnovationThe University of QueenslandBrisbaneQLDAustralia Centre for Mined Land Rehabilitation Sustainable Minerals InstituteThe University of QueenslandBrisbaneQLDAustralia

Neptunia amplexicaulis is an herbaceous legume endemic to the Richmond area in central Queensland,Australia and is one of the strongest known Selenium hyperaccumulators on earth,showing significant potential to be utilised in Se phytoextraction *** a protocol was established for in vitro micropropagation of Se hyperaccumula-tor *** using nodal segments from in vitro-germinated *** multiplication was achieved on Murashige and Skoog(MS)basal media supplemented with various concentrations of 6-Benzylaminopurine(BA)(1.0,2.0,3.0 mg L^(−1))alone or in combination with low levels of Naphthaleneacetic acid(NAA)(0.1,0.2,0.3 mg L^(−1)),with 2.0 mg L^(−1) BA+0.2 mg L^(−1) NAA found to be most *** shoots were rooted in vitro using NAA,with highest root induction rate of 30%observed at 0.2 mg L^(−1) *** 95%of the in vitro rooted shoots survived *** propagated plantlets were dosed with selenate/selenite solution and assessed for Se tissue concentrations using Inductively Coupled Plasma Atomic Emission Spectroscopy(ICP-AES)and found to retain their ability to *** protocol developed for this study has potential to be optimised for generating clonal plants of *** for use in research and phytoextraction industry applications.

关键词： Micropropagation Hyperaccumulation Phytoextraction Selenium Tissue culture Neptunia amplexicaulis

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Dynamic epi-transcriptomic landscape mapping with disease progression in estrogen receptor-positive breast cancer

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Cancer Communications 2023年第5期43卷 615-619页

作者： Stephen Keelan Mihaela Ola Sara Charmsaz Sinéad Cocchiglia Daniela Ottaviani Seán Hickey Siobhan Purcell Fiona Bane Aisling Hegarty Ben Doherty katherine Sheehan Lance Hudson Nicola Cosgrove Benjamin Roux Muriel Laine Geoffrey Greene Damir Varešlija Arnold Konrad Hill Leonie Young Endocrine Oncology Research Group Department of SurgeryRoyal College of Surgeons in IrelandUniversity of Medicine and Health SciencesDublinIreland Department of Surgery Beaumont HospitalDublinIreland Department of Pathology Beaumont HospitalDublinIreland Ben May Department for Cancer Research Department of Biochemistry and Molecular BiologyThe University of ChicagoChicagoILUSA The School of Pharmacy and Biomolecular Sciences The Royal College of Surgeons University of Medicine and Health SciencesDublinIreland Beaumont Royal College of Surgeons in Ireland Cancer Centre Beaumont HospitalDublinIreland

Dear Editor,The molecular determinants that drive breast cancer progression to metastasis are complex and partly controlled by nucleic acid epi-modifications[1].Although DNA-methyl modifications in breast cancer metastasis have been well described,there is limited understanding of the role of RNA methylation in advanced disease[2].This study aimed to provide an understanding on the role of the epitranscriptome in estrogen receptor-positive(ER+)breast cancer progression to metastasis.

关键词： breast metastasis cancer

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Performance and calibration of quark/gluon-jet taggers using 140 fb^(-1) of pp collisions at √s=13 TeV with the ATLAS detector

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Chinese Physics C 2024年第2期48卷 1-25页

作者： G. Aad B. Abbott K. Abeling N.J. Abicht S.H. Abidi A. Aboulhorma H. Abramowicz H. Abreu Y. Abulaiti B.S. Acharya C. Adam Bourdarios L. Adamczyk S.V. Addepalli M.J. Addison J. Adelman A. Adiguzel T. Adye A.A. Affolder Y. Afik M.N. Agaras J. Agarwala A. Aggarwal C. Agheorghiesei A. Ahmad F. Ahmadov W.S. Ahmed S. Ahuja X. Ai G. Aielli A. Aikot M. Ait Tamlihat B. Aitbenchikh I. Aizenberg M. Akbiyik T.P.A. Åkesson A.V. Akimov D. Akiyama N.N. Akolkar K. Al Khoury G.L. Alberghi J. Albert P. Albicocco G.L. Albouy S. Alderweireldt M. Aleksa I.N. Aleksandrov C. Alexa T. Alexopoulos F. Alfonsi M. Algren M. Alhroob B. Ali H.M.J. Ali S. Ali S.W. Alibocus M. Aliev G. Alimonti W. Alkakhi C. Allaire B.M.M. Allbrooke J.F. Allen C.A. Allendes Flores P.P. Allport A. Aloisio F. Alonso C. Alpigiani M. Alvarez Estevez A. Alvarez Fernandez M. Alves Cardoso M.G. Alviggi M. Aly Y. Amaral Coutinho A. Ambler C. Amelung M. Amerl C.G. Ames D. Amidei S.P. Amor Dos Santos K.R. Amos V. Ananiev C. Anastopoulos T. Andeen J.K. Anders S.Y. Andrean A. Andreazza S. Angelidakis A. Angerami A.V. Anisenkov A. Annovi C. Antel M.T. Anthony E. Antipov M. Antonelli F. Anulli M. Aoki T. Aoki J.A. Aparisi Pozo M.A. Aparo L. Aperio Bella C. Appelt A. Apyan N. Aranzabal S.J. Arbiol Val C. Arcangeletti A.T.H. Arce E. Arena J-F. Arguin S. Argyropoulos J.-H. Arling O. Arnaez H. Arnold G. Artoni H. Asada K. Asai S. Asai N.A. Asbah J. Assahsah K. Assamagan R. Astalos S. Atashi R.J. Atkin M. Atkinson H. Atmani P.A. Atmasiddha K. Augsten S. Auricchio A.D. Auriol V.A. Austrup G. Avolio K. Axiotis G. Azuelos D. Babal H. Bachacou K. Bachas A. Bachiu F. Backman A. Badea P. Bagnaia M. Bahmani A.J. Bailey V.R. Bailey J.T. Baines L. Baines O.K. Baker E. Bakos D. Bakshi Gupta V. Balakrishnan R. Balasubramanian E.M. Baldin P. Balek E. Ballabene F. Balli L.M. Baltes W.K. Balunas J. Balz E. Banas M. Bandieramonte A. Bandyopadhyay S. Bansal L. Barak M. Barakat E.L. Barberio D. Barberis M. Barbero M.Z. Barel K.N. Barends T. Barillari M-S. Barisits T. Barklow P. Baron D.A. Baron Mo The ATLAS Collaboration

The identification of jets originating from quarks and gluons,often referred to as quark/gluon tagging,plays an important role in various analyses performed at the Large Hadron Collider,as Standard Model measurements and searches for new particles decaying to quarks often rely on suppressing a large gluon-induced *** paper describes the measurement of the efficiencies of quark/gluon taggers developed within the ATLAS Collaboration,using √s=13 TeV proton–proton collision data with an integrated luminosity of 140 fb^(-1) collected by the ATLAS *** taggers with high performances in rejecting jets from gluon over jets from quarks are studied:one tagger is based on requirements on the number of inner-detector tracks associated with the jet,and the other combines several jet substructure observables using a boosted decision tree.A method is established to determine the quark/gluon fraction in data,by using quark/gluon-enriched subsamples defined by the jet *** in tagging efficiency between data and simulation are provided for jets with transverse momentum between 500 GeV and 2 TeV and for multiple tagger working points.

关键词： ATLAS JET QUARK GLUON TAGGING

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