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Animal Nutrition 2021年第3期7卷 812-822页

作者： Malgorzata Bialek Marian Czauderna Kamil Zaworski katarzyna krajewska The Kielanowski Institute of Animal Physiology and Nutrition Polish Academy of Sciences05-110 JablonnaPoland

The aim of the current study was to evaluate the impact of carnosic acid(CA),selenised yeast(^(Y)Se)and selenate(^(VI)Se)supplemented to diets,including fish oil(FO)and rapeseed oil(RO),on the content of fatty acids,total cholesterol(TCh),tocopherols and malondialdehyde in the fat located between the thigh muscles and the heart in ***-four male Corriedale lambs were divided into 4 groups of 6 *** were fed a diet with FO and RO(the control diet)or experimental diets containing RO,FO and CA with/without Se(as^(Y)Se or^(VI)Se).The experimental diets without/with^(Y)Se or^(VI)Se changed concentrations of fatty acids in the fat and heart compared to the *** experimental diets increased the levels of c11c14C20:2,c5c8c11c14C20:4,c5c8c11c14c17C20:5 and the sums of long-chain polyunsaturated fatty acids(LPUFA)and conjugated linoleic acid isomers in the fat compared to the *** experimental diet containing^(Y)Se or^(VI)Se increased the content of Se,TCh,c11c14C20:2,c8c11c14C20:3,c5c8c11c14C20:4,c5c8c11c14c17C20:5,c7c10c13c16c19C22:5,c4c7c10c13c16c19C22:6 and the concentration sum of n-3LPUFA,n-6LPUFA and tocopherols in the heart in comparison with the control diet and the diet containing only *** diets reduced the concentration of malon-dialdehyde in the fat and heart in comparison with the control *** dietary intervention has great potential for future practical and commercial implementations.

关键词： Selenium Carnosic acid Fatty acid Tocopherol Cholesterol Lamb

G protein-coupled estrogen receptor in colon function, immune regulation and carcinogenesis

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World Journal of Gastroenterology 2019年第30期25卷 4092-4104页

作者： Damian Jacenik Ellen J Beswick Wanda M krajewska Eric R Prossnitz Department of Cytobiochemistry Faculty of Biology and Environmental ProtectionUniversity of LodzLodz 90-236Poland Department of Internal Medicine School of Medicineand UNM Comprehensive Cancer CenterUniversity of New MexicoAlbuquerqueNM 87131United States Division of Gastroenterology Hepatology and NutritionDepartment of Internal MedicineSchool of MedicineUniversity of UtahSalt Lake CityUT 84132United States

Estrogens play important roles in the development and progression of multiple tumor *** evidence points to the significance of estrogen action not only in tumors of hormonally regulated tissues such as the breast,endometrium and ovary,but also in the development of colorectal cancer(CRC).The effects of estrogens in physiological and pathophysiological conditions are mediated by the nuclear estrogen receptorsαandβ,as well as the membranebound G protein-coupled estrogen receptor(GPER).The roles of GPER in CRC development and progression,however,remain poorly *** on the functions of GPER in the colon have shown that this estrogen receptor regulates colonic motility as well as immune responses in CRC-associated diseases,such as Crohn’s disease and ulcerative *** is also involved in cell cycle regulation,endoplasmic reticulum stress,proliferation,apoptosis,vascularization,cell migration,and the regulation of fatty acid and estrogen metabolism in CRC ***,multiple lines of evidence suggest that GPER may play an important role in colorectal *** this review,we present the current state of knowledge regarding the contribution of GPER to colon function and CRC.

关键词： G protein-coupled estrogen receptor Colorectal cancer Proliferation Migration Colonic motility Inflammatory bowel disease

Sperm counts in Asian men: Reviewing the trend of past 50 years

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Asian pacific Journal of Reproduction 2018年第2期7卷 87-92页

作者： Pallav Sengupta Sulagna Dutta Maiza Binti Tusimin Tulay Irez Elzbieta krajewska-Kulak Department of Physiology Faculty of MedicineMAHSA UniversityMalaysia Department of Obstetrics and Gynaecology Faculty of Medicine and Health SciencesUniversity Putra MalaysiaMalaysia Department of Histology and Embryology Medical FacultyBiruni UniversityIstanbulTurkey Department of Integrated Medical Care Faculty of Health SciencesMedical University of BialystokBialystokPoland

Objective:To reveal the trend in alterations of sperm counts in Asian men over the past 50 ***:This study reviewed all the published reports to unveil the specific pattern of alterations of sperm concentrations in Asian men from 1965 till 2015. The time-related changes in sperm concentration were studied using linear regression ***:The present study elucidated the trend using the reports from Carlsenet al(1965-1990) and non-Carlsen studies published until 2015, on fertile Asian men. In the reports of Carlsenet al., no overall declining trend in Asian men (r = 0.509,P= 0.760) was observed during this tenure, but non-Carsen reports showed a significant time-dependent decline of sperm concentration (r = -0.754, P = 0.005) in Asian men. This present review also showed a mild time-dependant decline in sperm concentration (-0.44×106/mL/year, 95% CI: -0.65 to -0.23;r = -0.473,P = 0.040) which accounted for an overall 22.17% decrease in past 50 ***:This study brings to the forefront that sperm concentration among Asian men follows a mild declining trend over the period of 50 years, and further studies addressing the causes of this decline are required.

关键词： Asian men Semen quality Sperm concentration Sperm count

Prices of Apartments in Relation to Noise Level in Poland

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Journal of Civil Engineering and Architecture 2013年第10期7卷 1189-1195页

作者： Kinga Szopifiska Malgorzata krajewska Department of Geomatics Geodesy and Spatial Economy University of Technology and Life Sciences Bydgoszcz 85-225 Poland

Acoustic climate of a given area ought to be a factor of considerable significance in investment processes in an urbanized area, especially in a residential real estate market, due to its extensive influence on the living standards of its inhabitants. In the following article, the authors have given an analysis of the residential market of housing units located in areas of acceptable and excessive noise levels in preselected regions of Poland. With this end in view, an entirely new source of information has been used in the research--an acoustic map which has been defined and applied to produce the outcome of the analysis. It allowed for the recognition of whether or not the noise level influences decisions made by investors existing in a local residential real estate market.

关键词： Acoustic climate noise strategic map residential real estate.

AAA+ ClpB chaperone as a potential virulence factor of pathogenic microorganisms: Other aspect of its chaperone function

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Advances in Bioscience and Biotechnology 2014年第1期5卷 31-35页

作者： Joanna krajewska Sabina Kedzierska-Mieszkowska Department of Biochemistry University of GdanskGdanskPoland

We describe and discuss the most recent findings on the activity and function of the oligomeric AAA+ chaperone ClpB from the Hsp100 protein family in pathogenic microorganisms. Pathogens are exposed to significant stress during infection of the host cells, frequently resulting in protein aggregation. The fact that ClpB is usually up-regulated in pathogens together with its immune reactivity suggests that ClpB acting as a protein disaggregase may be important for pathogen invasion and virulence. However, the specific function of ClpB in pathogenicity is still unclear. Since it is known that ClpB does not exist in mammals, it may serve as a potential target for the development of an effective therapy against several major bacterial diseases that do not respond to conventional antibiotics.

关键词： AAA+ATPase ClpB Molecular Chaperone Virulence Pathogens

Food Losses and Food Waste in the Context of Sustainable Development of the Food Sector

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Chinese Business Review 2015年第9期14卷 452-462页

作者： Beata Bilska Maigorzata Wrzosek Danuta Kotozyn-krajewska Karol Krajewski Warsaw University of Live Sciences--SGGW Warsaw Poland Koszalin University of Technology Koszalin Poland

Globally, about one third of all food produced is wasted every year. Losses take place along the entire food chain and they need to be analyzed and monitored due to their impact on the development of the food sector. In addition to quantitative losses, irrational use of food contributes to the depletion of natural resources （water and energy） and poses a threat to the environment, constituting a barrier to sustainable development of the food sector. The aim of this study was to establish the causes and effects of food waste throughout the food supply chain and to propose mitigation measures. Identified causes of food waste can be divided into two groups. The first are those that lead to the fact that food cannot be consumed （e.g., inadequate conditions of agricultural production and interruption of the cold chain）. In the second, those that cause food cannot be sold （e.g., wrong label and wrong product weight）. Most of the identified causes of food waste can be avoided （e.g., by improving the conditions of production, storage, and transportation）. However, it is not possible to eliminate all potential errors leading to food waste. It is therefore necessary to consider what action to take to use food as intended. One way to reduce losses and food waste can be re-distributing to charity.

关键词： food losses and food waste causes of food losses and food waste potential ways of reducing the wasteof food sustainable development

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现代装饰 2017年第9期 178-179页

作者： Przemyslaw Nowak Lech Moczuski Agata krajewska 彭佳波兰Mili Mlodzi Ludzie设计工作室不详

这座顶层公寓位于波兰,其原本的空间布局极不合理,起居室面积过小,而且最重要的是公寓最大的优点——两面巨大的窗户没有得到完全利用。公寓位于建筑物的顶层,因此视野非常广阔,可以俯瞰波兰的老城区和瓦尔塔河。针对这一特点,设计师的... 详细信息

这座顶层公寓位于波兰,其原本的空间布局极不合理,起居室面积过小,而且最重要的是公寓最大的优点——两面巨大的窗户没有得到完全利用。公寓位于建筑物的顶层,因此视野非常广阔,可以俯瞰波兰的老城区和瓦尔塔河。针对这一特点,设计师的首要想法就是对空间进行重新布局,让住户一进门就能看到优美的景色。

关键词：空间布局瓦尔中间位置几何元素橡木空间的