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Ultra-long-working-distance spectroscopy of single nanostructures with aspherical solid immersion microlenses

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Light(Science & Applications) 2020年第1期9卷 1561-1571页

作者： Aleksander Bogucki Lukasz Zinkiewicz Magdalena Grzeszczyk Wojciech Pacuski karol Nogajewski Tomasz kazimierczuk Aleksander Rodek Jan Suffczynski kenji Watanabe Takashi Taniguchi Piotr Wasylczyk Marek Potemski Piotr kossacki Faculty of Physics University of Warsawul.Pasteura 502-093 WarsawPoland National Institute for Materials Science TsukubaIbaraki 305-0044Japan Laboratoire National des Champs Magnetiques Intenses CNRS-UJF-UPS-INSAavenue des Martyrs 2538042 GrenobleFrance

In light science and applications,equally important roles are played by efficient light emitters/detectors and by the optical elements responsible for light extraction and *** latter should be simple,cost effective,broadband,versatile and compatible with other components of widely desired micro-optical ***,they should also operate without high-numerical-aperture ***,we demonstrate that all these requirements can be met with elliptical microlenses 3D printed on top of light ***,the microlenses we propose readily form the collected light into an ultra-low divergence beam(half-angle divergence below 1°)perfectly suited for ultra-longworking-distance optical measurements(600mm with a 1-inch collection lens),which are not accessible to date with other spectroscopic *** microlenses can be fabricated on a wide variety of samples,including semiconductor quantum dots and fragile van der Waals heterostructures made of novel two-dimensional materials,such as monolayer and few-layer transition metal dichalcogenides.

关键词： versatile latter optics

THE SLOW TRAIN TO XINJIANG A ride through Chinazs rapidly changing Western frontier

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城市漫步（上海版、英文） 2015年第1期 30-33页

作者： WILL PHILIPPS karol INE kAN 不详

"keyi le!"exclaims the man I'm sharing a train compart-ment with,as I lay down on my cabin bed.I've just proved to him that all 193 centimeters of me can comfortably lie straight on the sleeper berth(there had been some doubt when we first boarded).The man's name is Junfeng,and he's a mechanic from Turpan,an ancient city close to Urumqi,capital of the Uyghur Autonomous Region,and our next *** ethnically Han family moved from Shandong two generations ago,and he continues to live in Xinjiang with his wife and *** has no plans to move back east.

关键词： frontier doubt straight

Dysregulation of IL-34 ligation to SDC-1 mitigates collagen-induced arthritis

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Cellular & Molecular Immunology 2022年第9期19卷 1070-1072页

作者： Anja Meyer Ryan Sienes Brian Zanotti katrien van Raemdonck karol Palasiewicz Daniel P.Mass Michael V.Volin Shiva Shahrara Jesse Brown VA Medical Center ChicagoILUSA Department of Medicine Division of RheumatologyThe University of Illinois at ChicagoChicagoILUSA Department of Microbiology and Immunology Midwestern UniversityDowners GroveILUSA Department of Orthopedic Surgery The University of Illinois at ChicagoChicagoILUSA

IL-34 is a novel biomarker for rheumatoid arthritis(RA),as its serum levels are linked to C-reactive protein,erythrocyte sedimentation rate,rheumatoid factor(RF),IL-6 and radiographic progression[1,2].IL-34 reprograms naïve circulating M0 cells into glycolytic(CD14^(+)CD86^(+)GLUT1^(high))M34 macrophages(MΦs)by binding to its pathogenic receptor,SDC-1,which controls the activation of its coreceptor/M-CSFR[3].Glycolytic M34 MΦs are primed to differentiate into osteoclasts through SDC-1 ligation[3].

关键词： CD86 GLUT1 sedimentation

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沥青体系的分子动力学研究进展及展望

材料导报 2020年第19期34卷 19083-19093页

作者：何亮李冠男郑雨丰 Alessio Alexiadis Jan Valentin karol J kowalski 重庆交通大学交通土建材料国家地方联合实验室重庆400074 哈尔滨工业大学交通科学与工程学院哈尔滨150090 伯明翰大学化学工程学院伯明翰B152TT 捷克理工大学土木工程学院布拉格16629 华沙理工大学土木工程学院华沙00-637

随着我国道路工程的飞速发展,沥青混凝土在路面工程中有越来越广泛的应用。近年来,沥青材料的研究已不仅局限于宏观性能试验,还拓展到介观与微观层面对沥青材料进行多尺度研究。分子动力学方法属于微观研究方法的一种,它是通过积分算法... 详细信息

随着我国道路工程的飞速发展,沥青混凝土在路面工程中有越来越广泛的应用。近年来,沥青材料的研究已不仅局限于宏观性能试验,还拓展到介观与微观层面对沥青材料进行多尺度研究。分子动力学方法属于微观研究方法的一种,它是通过积分算法模拟研究对象在不同条件下的分子运动轨迹与体系能量变化,并分析模拟数据得出结论。该方法已被广泛应用于分子尺度下路面沥青材料设计与微观机理研究,其优势在于从分子运动的角度解释沥青体系的各种现象与性质。因此,许多学者采用宏观试验和分子动力学模拟相结合的多尺度方法研究沥青体系,这将推动沥青材料的进一步发展。本文对沥青体系的分子动力学进行了全面的分析,构建了沥青体系分子动力学模型的一般平衡步骤,提出采用密度、玻璃态转变温度、黏度、溶解度参数等对沥青体系分子动力学模型的有效性进行验证。综合分析了分子动力学方法对沥青纳米聚集、自修复、改性、老化、界面黏附等行为机理的研究进展,提出采用耗散粒子动力学与粗粒化分子动力学对现阶段沥青体系分子动力学的研究尺度进行扩展。研究结果表明,沥青类材料的分子动力学方法还处于早期探索阶段,但其发展潜力极大,利用分子动力学方法研究沥青体系各组分分子的动力学行为,可揭示常规试验无法观察到的分子含时运动规律,预测沥青材料的宏观性能并针对沥青的分子结构提出其路用性能改善措施,从分子尺度上推动沥青路面多尺度试验仿真方法的发展与完善,为沥青材料基因组的开发研究奠定基础。

关键词：分子动力学道路沥青耗散粒子动力学粗粒化分子动力学

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利用高分辨辉光放电质谱技术对难熔金属材料进行痕量元素定量和深度剖面分析

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冶金分析 2010年第2期30卷 1-7页

作者： PUTYERA karol BOYEA Nick CUQ Nicole MICHELLON Cyril 埃文斯分析小组-纽约Shiva技术公司欧洲Shiva技术公司

直接采样的高分辨辉光放电质谱(GDMS)是当今高纯固体常规分析中可用的高灵敏度分析方法之一。这种多元素分析技术通常用于主量化学成分的定量分析、监测元素质量分数随微米级深度(深度分布)的变化,或用于对多种固体和镀层上肉眼可见体... 详细信息

直接采样的高分辨辉光放电质谱(GDMS)是当今高纯固体常规分析中可用的高灵敏度分析方法之一。这种多元素分析技术通常用于主量化学成分的定量分析、监测元素质量分数随微米级深度(深度分布)的变化,或用于对多种固体和镀层上肉眼可见体积的高灵敏度的分布研究,包括纯金属、高温合金、陶瓷或其中陶瓷金属。由于GDMS的检测几乎涵盖了所有方法,因此在监测痕量级的多元素含量方面是最具成本优势的。另外,它使对在包含绝缘层和(或)镀层及两者化合物的平面上的高灵敏度的含量深度分布分析成为可能。本文着重介绍直流辉光质谱技术用于监测痕量至超含量元素分析技术目前的进展以及直接采样分析实践中应当采用的策略。

关键词：高温材料难熔金属痕量杂质元素浓度分布辉光放电质谱法

Macrophages are the primary effector cells in IL-7-induced arthritis

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Cellular & Molecular Immunology 2020年第7期17卷 728-740页

作者： Seung-jae kim Huan J.Chang Michael VVolin Sadiq Umar katrien Van Raemdonck Aimee Chevalier karol Palasiewicz John W.Christman Suncica Volkov Shiva Arami Mehrdad Maz Anjali Mehta Ryan k.Zomorrodi David A.Fox Nadera Sweiss Shiva Shahrara Division of Rheumatology Jesse Brown VAMedical CenterChicagoIL 60612USA Department of Medicine Division of RheumatologyUniversity of Illinois at ChicagoChicagoIL 60612USA Department of Microbiology and Immunology Chicago College of Osteopathic MedicineMidwestern UniversityDowners GroveIL 60515USA Pulmonary Critical Care and Sleep MedicineOhio State University Wexner Medical CenterDavis Heart and Lung Research InstituteColumbusOH 43210USA Division of Allergy Clinical Immunology and RheumatologyThe University of Kansas Medical CenterKansas CityKS 66160USA Division of Rheumatology and Clinical Autoimmunity Center of Excellence University of MichiganAnn ArborMI 481096USA

Synovial macrophages are crucial in the development of joint inflammation and bone damage;however, the pathways that controlmacrophage remodeling in inflammatory M1 cells or bone-eroding osteoclasts are not fully understood. We determined thatelevated IL-7R/CD127 expression is the hallmark of rheumatoid arthritis (RA) M1 macrophages and that these cells are highlyresponsive to interleukin-7 (IL-7)-driven osteoclastogenesis. We established that lipopolysaccharide (LPS), interferon-γ (IFNγ), andtumor necrosis factor-α (TNFα), the classic M1 macrophage mediators, enhance IL-7R expression in RA and murine *** local expression of IL-7 provokes arthritis, predominantly through escalating the number of F480^(+)iNOS^(+) cells rather than CD3^(+)T cells. Ectopic LPS injection stabilizes IL-7-induced arthritis by increasing myeloid IL-7R expression, in part via IFNγ ***, in RAG−/− mice, IL-7-mediated arthritis is suppressed because of the reduction in myeloid IL-7R expression due to the lackof IFNγ. Moreover, the amelioration of IL-7-induced arthritis by anti-TNF therapy is due to a decrease in the number of cells in theunique F480^(+)iNOS^(+)IL-7R^(+)CCL5^(+) subset, with no impact on the F480^(+)Arginase^(+) cell or CD3^(+) T cell frequency. Consistent with thepreclinical findings, the findings of a phase 4 study performed with RA patients following 6 months of anti-TNF therapy revealedthat IL-7R expression was reduced without affecting the levels of IL-7. This study shifts the paradigm by discovering that IL-7-induced arthritis is dependent on F480^(+)iNOS^(+)IL-7R^(+)CCL5^(+) cell function, which activates TH-1 cells to amplify myeloid IL-7Rexpression and disease severity.

关键词： myeloid elevated inflammation

3D resistive RAM cell design for high-density storage class memory—a review

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Science China(Information Sciences) 2016年第6期59卷 35-55页

作者： Boris HUDEC Chung-Wei HSU I-Ting WANG Wei-Li LAI Che-Chia CHANG Taifang WANG karol FRHLICH Chia-Hua HO Chen-Hsi LIN Tuo-Hung HOU Department of Electronics Engineering and Institute of Electronics National Chiao-Tung University Institute of Electrical Engineering Slovak Academy of Sciences Winbond Electronics Corporation

In this article, we comprehensively review recent progress in the Re RAM cell technology for 3D integration focusing on a material/device level. First we briefly mention pioneering work on high-density crossbar Re RAM arrays which paved the way to 3D integration. We discuss the two main proposed 3D integration schemes—3D horizontally stacked Re RAM vs 3D Vertical Re RAM and their respective advantages and disadvantages. We follow with the detailed memory cell design on important work in both areas, utilizing either filamentary or interface-limited switching mechanisms. We also discuss our own contributions on Hf O2-based filamentary 3D Vertical Re RAM as well as Ta Ox/Ti O2 bilayer-based self-rectifying 3D Vertical Re RAM. Finally,we summarize the present status and provide an outlook for the nearterm future.

关键词： RRAM ReRAM resistive switching crossbar cross-point storage class memory 3D integration atomic layer deposition selector

Is more evidence needed for thrombectomy in basilar artery occlusion? The BASICS and BEST meta- analytical approaches

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Stroke & Vascular Neurology 2021年第4期6卷 671-672,I0094-I0096页

作者： Davi J Fontoura Solla Felipe Coelho Argolo karol P Budohoski Angelos G kolias JoséGuilherme M P Caldas Jamary Oliveira-Filho Division of Neurosurgery Department of NeurologyUniversity of Sao PauloSao PauloBrazil NIHR Global Health Research Group on Neurotrauma Cambridge UniversityCambridgeUK Machine Learning for Mental Health Lab King's College LondonLondonUK Division of Neurosurgery Department of Clinical NeurosciencesAddenbrooke's HospitalCambridge UniversityCambridgeUK Radiology University of Sao PauloSao PauloBrazil Postgraduate Program in Health Sciences Federal University of BahiaSalvadorBahiaBrazil

INTRODUCTION The benefit of mechanical thrombectomy for stroke associated with anterior circulation large vessel occlusion(LVO)is well established and among the most effective treatments in medicine.1 Stroke associated with basilar artery occlusion(BAO)was not included in the seminal thrombectomy randomised clin-ical trials(RCTs).BAO accounts for 1%of the ischaemic strokes and 5%-10%of the LVO,but 70%-80%of BAO victims evolve to death or full dependence.23 The terminal nature of the brainstem and thalamic circulations may predispose to such dismal *** two RCT designed to assess the efficacy of early(ke is well settled;BAO stroke shares a similar physiopathology with very poor prog-nosis.

关键词： throm occlusion basilar

Generation of sub-100 fs pulses tunable from 1700 to 2100 nm from a compact frequency-shifted Er-fiber laser

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Photonics Research 2017年第3期5卷 151-155页

作者： GRZEGORZ SOBON TADEUSZ MARTYNkIEN karol TARNOWSkI PAWEL MERGO JAROSLAW SOTOR Laser & Fiber Electronics Group Faculty of ElectronicsWroclaw University of Science and Technology Department of Optics and Photonics Faculty of Fundamental Problems of TechnologyWroclaw University of Science and Technology Laboratory of Optical Fiber Technology Maria Curie-Sklodowska University

We report generation of sub-100 fs pulses tunable from 1700 to 2100 nm via Raman soliton self-frequency *** nonlinear shift occurs in a highly nonlinear fiber, which is pumped by an Er-doped fiber laser. The whole system is fully fiberized, without the use of any free-space optics. Thanks to its exceptional simplicity, the setup can be considered as an alternative to mode-locked Tm-and Ho-doped fiber lasers.

关键词： of as be Generation of sub-100 fs pulses tunable from 1700 to 2100 nm from a compact frequency-shifted Er-fiber laser in nm from

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