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Neutron-induced nuclear recoil background in the PandaX-4T experiment

chinese Physics c 2022年第11期46卷 262-274页

作者： Zhou Huang Guofang Shen Qiuhong Wang Abdusalam Abdukerim Zihao Bo Wei chen Xun chen Yunhua chen chen cheng Yunshan cheng Xiangyi cui Yingjie Fan Deqing Fang changbo Fu Mengting Fu Lisheng Geng karl Giboni Linhui Gu Xuyuan Guo chencheng Han Ke Han changda He Jinrong He Di Huang Yanlin Huang Ruquan Hou Xiangdong Ji Yonglin Ju chenxiang Li Mingchuan Li Shu Li Shuaijie Li Qing Lin Jianglai Liu Xiaoying Lu Lingyin Luo Wenbo Ma Yugang Ma Yajun Mao Yue Meng Xuyang Ning Ningchun Qi Zhicheng Qian Xiangxiang Ren Nasir Shaheed changsong Shang Lin Si Wenliang Sun Andi Tan Yi Tao Anqing Wang Meng Wang Shaobo Wang Siguang Wang Wei Wang Xiuli Wang Zhou Wang Mengmeng Wu Weihao Wu Jingkai Xia Mengjiao Xiao Xiang Xiao Pengwei Xie Binbin Yan Xiyu Yan Jijun Yang Yong Yang chunxu Yu Jumin Yuan Ying Yuan Dan Zhang Minzhen Zhang Peng Zhang Tao Zhang Li Zhao Qibin Zheng Jifang Zhou Ning Zhou Xiaopeng Zhou Yong Zhou School of Physics and Astronomy Shanghai Jiao Tong UniversityKey Laboratory for Particle Astrophysics and Cosmology(MoE)Shanghai Key Laboratory for Particle Physics and CosmologyShanghai 200240China School of Physics Beihang UniversityBeijing 102206China Key Laboratory of Nuclear Physics and Ion-beam Application(MOE) Institute of Modern PhysicsFudan UniversityShanghai 200433China Shanghai Jiao Tong University Sichuan Research Institute Chengdu 610213China Yalong River Hydropower Development company Ltd.288 Shuanglin RoadChengdu 610051China School of Physics Sun Yat-Sen UniversityGuangzhou 510275China Research center for Particle Science and Technology Institute of Frontier and Interdisciplinary SciencShandong UniversityQingdao 266237China Key Laboratory of Particle Physics and Particle Irradiation of Ministry of Education Shandong UniversityQingdao 266237China Tsung-Dao Lee Institute Shanghai Jiao Tong UniversityShanghai200240China School of Physics Nankai UniversityTianjin 300071China School of Physics Peking UniversityBeijing 100871China Beijing Key Laboratory of Advanced Nuclear Materials and Physics Beihang UniversityBeijing102206China School of Physics and Microelectronics Zhengzhou UniversityZhengzhouHenan 450001China School of Medical Instrument and Food Engineering University of Shanghai for Science and TechnologyShanghai 200093China Department of Physics University of MarylandCollege ParkMaryland 20742USA School of Mechanical Engineering Shanghai Jiao Tong UniversityShanghai 200240China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China Department of Modern Physics University of Science and Technology of ChinaHefei 230026China SJTU Paris Elite Institute of Technology Shanghai Jiao Tong UniversityShanghai200240China

Neutron-induced nuclear recoil background is critical to dark matter searches in the PandaX-4T liquid xenon *** this study,we investigate the features of neutron background in liquid xenon and evaluate its contribution in single scattering nuclear recoil events using three *** first method is fully based on Monte carlo *** last two are data-driven methods that also use multiple scattering signals and high energy signals in the *** the PandaX-4T commissioning data with an exposure of 0.63 tonne-year,all these methods give a consistent result,i.e.,there are 1.15±0.57 neutron-induced backgrounds in the dark matter signal region within an approximated nuclear recoil energy window between 5 and 100 keV.

关键词： dark matter neutron background multiple scattering high energy gamma

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Panda X-III： Searching for neutrinoless double beta decay with high pressure ^(136)Xe gas time projection chambers

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Science china(Physics,Mechanics & Astronomy) 2017年第6期60卷 8-47页

作者： Xun chen chang Bo Fu Javier Galan karl Giboni Franco Giuliani Ling Hui Gu Ke Han Xiang Dong Ji Heng Lin Jiang Lai Liu Kai Xiang Ni Hiroki Kusano Xiang Xiang Ren Shao Bo Wang Yong Yang Dan Zhang Tao Zhang Li Zhao Xiang Ming Sun Shou Yang Hu Si Yu Jian Xing Long Li Xiao Mei Li Hao Liang Huan Qiao Zhang Ming Rui Zhao Jing Zhou Ya Jun Mao Hao Qiao Si Guang Wang Ying Yuan Meng Wang Amir N.Khan Neill Raper Jian Tang Wei Wang Jia Ning Dong chang Qing Feng cheng Li Jian Bei Liu Shu Bin Liu Xiao Lian Wang Dan Yang Zhu Juan F.castel Susana cebri'an Theopisti Dafni Javier G.Garza Igor G.Irastorza Francisco J.Iguaz Gloria Luz ′on Hector Mirallas Stephan Aune Eric Berthoumieux Yann Bedfer Denis calvet Nicole d'Hose Alain Delbart Maria Diakaki Esther Ferrer-Ribas Andrea Ferrero Fabienne Kunne Damien Neyret Thomas Papaevangelou Franck Sabatie Maxence Vanderbroucke AnDi Tan Wick Haxton Yuan Mei chinorat Kobdaj Yu-Peng Yan NPAc and Department of Physics and Astronomy Shanghai Jiao Tong University Shanghai Laboratory for Particle Physics and Cosmology Shanghai 200240 China college of Physical Science and Technology Central China Normal University Wuhan 430079 China china Institute of Atomic Energy Beijing 102413 China School of Physics Peking University Beijing 100871 China School of Physics and Key Laboratory of Particle Physics and Particle Irradiation (MOE) Shandong University Jinan 250100 China School of Physics and Engineering Sun Yat-Sen University Guangzhou 510275 China Department of Modern Physics University of Science and Technology of China Hefei 230026 China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of China Hefei 230026 China University ofZaragoza C/P Cerbuna 12 50009 Zaragoza Spain IRFU CEA Universite Paris-Saclay F-91191 Gif-sur-Yvette France Department of Physics University of Maryland College Park MD 20742 USA Nuclear Science Division Lawrence Berkeley National Laboratory Berkeley CA 94720 USA center for Excellence in High Energy Physics and Astrophysics Suranaree University of Technology Nakhon Ratchasima 30000 Thailand

Searching for the neutrinoless double beta decay(NLDBD)is now regarded as the topmost promising technique to explore the nature of neutrinos after the discovery of neutrino masses in oscillation *** X-III(particle and astrophysical xenon experiment III)will search for the NLDBD of136Xe at the china Jin Ping Underground Laboratory(cJPL).In the first phase of the experiment,a high pressure gas Time Projection chamber(TPc)will contain 200 kg,90%136Xe enriched gas operated at10 *** pitch micro-pattern gas detector(Microbulk Micromegas)will be used at both ends of the TPc for the charge readout with a cathode in the *** signals can be used to reconstruct the electron tracks of the NLDBD events and provide good energy and spatial *** detector will be immersed in a large water tank to ensure～5 m of water shielding in all *** second phase,a ton-scale experiment,will consist of five TPcs in the same water tank,with improved energy resolution and better control over backgrounds.

关键词： neutrinoless double beta decay lepton number violation underground experiment TPc Micromegas

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Searching for neutrino-less nouble neta necay of 136Xe with PandaX-Ⅱ liquid xenon detector

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chinese Physics c 2019年第11期43卷 1-10页

作者： Kaixiang Ni Yihui Lai Abdusalam Abdukerim Wei chen Xun chen Yunhua chen Xiangyi cui Yingjie Fan Deqing Fang changbo Fu Lisheng Geng karl Giboni Franco Giuliani Linhui Gu Xuyuan Guo Ke Han changda He Di Huang Yan Huang Yanlin Huang Zhou Huang Peng Ji Xiangdong Ji Yonglin Ju Kun Liang Huaxuan Liu Jianglai Liu Wenbo Ma Yugang Ma Yajun Mao Yue Meng Parinya Namwongsa Jinhua Ning Xuyang Ning Xiangxiang Ren changsong Shang Lin Si Andi Tan Anqing Wang Hongwei Wang Meng Wang Qiuhong Wang Siguang Wang Xiuli Wang Zhou Wang Mengmeng Wu Shiyong Wu Jingkai Xia Mengjiao Xiao Pengwei Xie Binbin Yan Jijun Yang Yong Yang chunxu Yu Jumin Yuan Dan Zhang Hongguang Zhang Tao Zhang Li Zhao Qibin Zheng Jifang Zhou Ning Zhou Xiaopeng Zhou INPAc and School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghai Laboratory for Particle Physics and CosmologyShanghai 200240China Yalong River Hydropower Development company Ltd.288 Shuanglin RoadChengdu 610051China School of Physics Nankai UniversityTianjin 300071China Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China School of Physics&International Research center for Nuclei and Particles in the cosmos&Beijing Key Laboratory of Advanced Nuclear Materials and Physics Beihang UniversityBeijing 100191China School of Medical Instrument and Food Engineering University of Shanghai for Science and TechnologyShanghai 200093China Tsung-Dao Lee Institute Shanghai 200240China School of Mechanical Engineering Shanghai Jiao Tong UniversityShanghai 200240China School of Physics Peking UniversityBeijing 100871China Department of Physics University of MarylandCollege ParkMaryland 20742USA School of Physics and Key Laboratory of Particle Physics and Particle Irradiation(MOE) Shandong UniversityJinan 250100China center of High Energy Physics Peking UniversityBeijing 100871China

We report the Neutrino-less Double Beta Decay（NLDBD） search results from PandaX-Ⅱ dual-phase liquid xenon time projection *** total live time used in this analysis is 403.1 days from June 2016 to *** NLDBD-optimized event selection criteria,we obtain a fiducial mass of 219 kg of natural *** accumulated xenon exposure is 242 kg yr,or equivalently 22.2 kg yr of 136Xe *** the region around 136Xe decay Q-value of 2458 keV,the energy resolution of PandaX-Ⅱ is 4.2%.We find no evidence of NLDBD in PandaX-Ⅱand establish a lower limit for decay half-life of 2.1×1023yr at the 90% confidence level,which corresponds to an effective Majorana neutrino mass mββ <（1.4-3.7） *** is the first NLDBD result reported from a dual-phase xenon experiment.

关键词： neutrino-less double beta decay dark matter underground physics liquid xenon detector

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Results of dark matter search using the full PandaX-Ⅱ exposure

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chinese Physics c 2020年第12期44卷 184-200页

作者： Qiuhong Wang Abdusalam Abdukerim Wei chen Xun chen Yunhua chen chen cheng Xiangyi cui Yingjie Fan Deqing Fang changbo Fu Mengting Fu Lisheng Geng karl Giboni Linhui Gu Xuyuan Guo Ke Han changda He Di Huang Yan Huang Yanlin Huang Zhou Huang Xiangdong Ji Yonglin Ju Shuaijie Li Huaxuan Liu Jianglai Liu Wenbo Ma Yugang Ma Yajun Mao Yue Meng Kaixiang Ni Jinhua Ning Xuyang Ning Xiangxiang Ren changsong Shang Lin Si Guofang Shen Andi Tan Anqing Wang Hongwei Wang Meng Wang Siguang Wang Wei Wang Xiuli Wang Zhou Wang Mengmeng Wu Shiyong Wu Weihao Wu Jingkai Xia Mengjiao Xiao Pengwei Xie Binbin Yan Jijun Yang Yong Yang chunxu Yu Jumin Yuan Ying Yuan Xinning Zeng Dan Zhang Tao Zhang Li Zhao Qibin Zheng Jifang Zhou Ning Zhou Xiaopeng Zhou INPAc and School of Physics and Astronomy Shanghai Jiao Tong UniversityMOE Key Lab for Particle PhysicsAstrophysics and CosmologyShanghai Key Laboratory for Particle Physics and CosmologyShanghai 200240China Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China University of chinese Academy of Sciences Beijing 100049China Shanghai Jiao Tong University Sichuan Research Institute Chengdu 610213China Yalong River Hydropower Development company Ltd.288 Shuanglin RoadChengdu 610051China School of Physics Sun Yat-Sen UniversityGuangzhou 510275China Tsung-Dao Lee Institute Shanghai 200240China School of Physics Nankai UniversityTianjin 300071China Key Laboratory of Nuclear Physics and Ion-beam Application(MOE) Institute of Modern PhysicsFudan UniversityShanghai 200433China School of Physics Peking UniversityBeijing 100871China School of Physics Beihang UniversityBeijing 100191China International Research center for Nuclei and Particles in the cosmos&Beijing Key Laboratory of Advanced Nuclear Materials and Physics Beihang UniversityBeijing 100191China School of Medical Instrument and Food Engineering University of Shanghai for Science and TechnologyShanghai 200093China Department of Physics University of MarylandCollege ParkMaryland 20742USA School of Mechanical Engineering Shanghai Jiao Tong UniversityShanghai 200240China School of Physics and Key Laboratory of Particle Physics and Particle Irradiation(MOE) Shandong UniversityJinan 250100China Shanghai Advanced Research Institute Chinese Academy of SciencesShanghai 201210China center for High Energy Physics Peking UniversityBeijing 100871China

We report the dark matter search results obtained using the full 132 ton·day exposure of the PandaX-II experiment,including all data from March 2016 to August *** significant excess of events is identified above the expected *** limits are set on the spin-independent dark matter-nucleon *** lowest 90%confidence level exclusion on the spin-independent cross section is 2.2×10−46 cm2 at a WIMP mass of 30 GeV/c2.

关键词： dark matter direct detection liquid xenon

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培美曲塞加铂类联合或不联合帕博利珠单抗对初治转移性非鳞状NScLc患者的疗效与安全性分析：KEYNOTE-189研究方案指定的最终分析

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中国肺癌杂志 2022年第6期25卷 443-456页

作者：周彩存 Delvys RODRíGUEZ-ABREU S.F.POWELL M.J.HOcHMAIR S.GAD GEEL E.ESTEBAN E.FELIP G.SPERANZA F.De ANGELIS M.DóMINE S.Y.cHENG H.G.BIScHOFF N.PELED M.REcK R.HUI E.B.GARON M.BOYER T.KURATA J.YANG M.c.PIETANZA F.SOUZA M.c.GARASSINO 同济大学附属上海市肺科医院肿瘤科 Medical Oncology Complejo Hospitalario Universitario Insular Materno-Infantil de Gran CanariaUniversidad de Las Palmas de Gran Canaria Oncology Sanford Health 4. Department of Respiratory and Critical Care MedicineKarl Landsteiner Institute of Lung Research and Pulmonary Oncology Thoracic Oncology Karmanos Cancer InstituteWayne State University Department of Medical Oncology Hospital Universitario Central de Asturias Medical Oncology Department Vall d'Hebron UniversityVall d'Hebron Institute of Oncology (VHIO) 8. Centre Integre de Cancerologie de la MontérégieH?pital Charles-Le Moyne 9. Medical Oncology DepartmentHospital Universitario Fundacidn Jiménez DiazIIS-FJD Sunnybrook Health Sciences centre Thoraxklinik Heidelberg Department of Oncology Shaare Zedek Medical Center Lungenclinic Airway Research Center NorthGerman Center for Lung Research Department of Medical Oncology Westmead Hospital and University of Sydney Department of Medicine David Geffen School of Medicine at UCLA Department of Medical Oncology Chris O'Brien Lifehouse Department of Thoracic Oncology Kansai Medical University Hospital Merck & co. Inc. Fondazione IRccS Istituto Nazionale dei Tumori University of chicago Medicine & Biological Sciences Knapp Center for Biomedical Discovery

背景在KEYNOTE-189此项Ⅲ期研究(NcT02578680)中,与安慰剂联合培美曲塞加铂类相比,帕博利珠单抗联合培美曲塞加铂类化疗(培美曲塞-铂类)显著改善了初治转移性非鳞状非小细胞肺癌(non-small cell lung cancer,NScLc)患者的总生存期(over... 详细信息

背景在KEYNOTE-189此项Ⅲ期研究(NcT02578680)中,与安慰剂联合培美曲塞加铂类相比,帕博利珠单抗联合培美曲塞加铂类化疗(培美曲塞-铂类)显著改善了初治转移性非鳞状非小细胞肺癌(non-small cell lung cancer,NScLc)患者的总生存期(overall survival,OS)和无进展生存期(progression-free survival,PFS)。本研究报告了研究方案指定的最终分析的疗效结局,包括从培美曲塞-铂类交叉至帕博利珠单抗治疗的患者,以及完成35个周期(约2年)帕博利珠单抗治疗组的疗效。方法符合条件的患者以2:1随机分配至帕博利珠单抗,每3周一次,200 mg (n=410)或安慰剂(n=206)(共35周期,约2年),加上4个周期的培美曲塞(500 mg/m~2)和由研究者选择的每3周顺铂(75 mg/m~2)或卡铂(曲线下面积5 mg/min/mL)治疗,随后使用培美曲塞直至疾病进展。若符合纳入标准,分配至安慰剂联合培美曲塞加铂类治疗的患者可在疾病进展时转向帕博利珠单抗治疗。主要研究终点为OS和PFS。结果中位随访31.0个月,无论PD-L1的表达水平如何,与安慰剂联合培美曲塞-铂类治疗相比,帕博利珠单抗联合培美曲塞-铂类治疗可使患者的OS[风险比(hazard ratio,HR)为0.56;95%可信区间(confidence interval,cI) 0.46-0.69]和PFS (HR=0.49;95%cI:0.41-0.59)显著获益。接受帕博利珠单抗联合培美曲塞-铂类治疗的患者客观缓解率(objective response rate,ORR)(48.3%vs 19.9%)和第二次/后续无进展生存期(PFS2;HR=0.50;95%cI:0.41-0.61)均得到改善。安慰剂联合培美曲塞-铂类组的84例患者(40.8%)交叉至帕博利珠单抗治疗组。72.1%的接受帕博利珠单抗联合培美曲塞-铂类的患者和66.8%的接受安慰剂联合培美曲塞-铂类的患者发生了3级-5级不良事件。56例患者完成了35个周期(约2年)的帕博利珠单抗治疗;ORR为85.7%,53例(94.6%)患者存活至数据截止时间。结论与安慰剂联合培美曲塞-铂类治疗相比,帕博利珠单抗联合培美曲塞-铂类可持续提高疗效,且安全性可控。该研究结果支持将帕博利珠单抗联合培美曲塞-铂类作为初治转移性非鳞状NScLc患者的一线治疗方案。

关键词：帕博利珠单抗化疗非鳞状非小细胞肺癌

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穿心莲指纹图谱和不同产地质量研究

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中国现代中药 2009年第6期11卷 21-24,33页

作者：李军段然黄雯李卓明毕文川陈小莺董婷霞詹华强香港科技大学生物系及中药研发中心

目的:建立穿心莲药材有效的质量评价方法。方法:通过建立HPLc指纹图谱和有效成分的含量测定,对来自10个不同产地的穿心莲药材进行分析。色谱条件为Alltima c18色谱柱(4.6mm×250mm,5μm),流动相为乙腈-水系统,梯度洗脱,流速***-1,指纹... 详细信息

目的:建立穿心莲药材有效的质量评价方法。方法:通过建立HPLc指纹图谱和有效成分的含量测定,对来自10个不同产地的穿心莲药材进行分析。色谱条件为Alltima c18色谱柱(4.6mm×250mm,5μm),流动相为乙腈-水系统,梯度洗脱,流速***-1,指纹图谱检测波长为215nm,穿心莲内酯和脱水穿心莲内酯含量测定的检测波长分别为225nm和254nm。结果:得到分离度、重现性均较好的穿心莲药材HPLc指纹图谱,标示了10个共有色谱峰,对10批来自不同产地穿心莲样品的色谱指纹图谱进行了相似度评价;应用HPLc-DAD测定了不同产地穿心莲样品中穿心莲内酯和脱水穿心莲内酯的含量,结果显示,穿心莲药材中穿心莲内酯和脱水穿心莲内酯总量介于1.09%～4.47%。结论:该方法简便准确,灵敏度高、重复性好,可以作为穿心莲药材的质量控制方法,此方法已被《香港中药材标准》采用。建议HPLc指纹图谱用于穿心莲药材的质量控制,穿心莲内酯和脱水穿心莲内酯的总量不得低于1.0%。

关键词：质量评价穿心莲 HPLc指纹图谱含量测定

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接触性内窥镜在喉病变诊断中的应用

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山东大学基础医学院学报 2003年第2期17卷 80-82页

作者：李勇 c.Arens 栾信庸潘新良许风雷王惠忠 H.Glanz 山东大学齐鲁医院耳鼻咽喉-头颈外科济南250012 德国Giessen大学医院耳鼻咽喉-头颈外科

目的 :研究接触性内窥镜在喉病变 ,特别是喉癌时做微创的病理学图像检查方法。方法 :在显微支撑喉镜下 ,在 84例喉内病变黏膜处涂 1%的美蓝染色 ,用 6 0×和 15 0×放大倍数的接触式内窥镜 (karl -Storz 8715AA ,0° ,8715AB ,30° ,直... 详细信息

目的 :研究接触性内窥镜在喉病变 ,特别是喉癌时做微创的病理学图像检查方法。方法 :在显微支撑喉镜下 ,在 84例喉内病变黏膜处涂 1%的美蓝染色 ,用 6 0×和 15 0×放大倍数的接触式内窥镜 (karl -Storz 8715AA ,0° ,8715AB ,30° ,直径均为 5 .5mm ,长度 2 3mm)放置于黏膜表面 ,观察其病理变化 ,并与活检结果比较。结果 :接触性内窥镜的电子图像可较清晰的显示表面黏膜不同病变细胞及核的大小、形状、排列、与胞浆的比例、致密度和着色情况 ,有无中空细胞、核角蛋白 ,黏膜下微血管的排列情况。病理改变为 :任克式水肿 (n =8) ,慢性喉炎 (n =15 ) ,喉乳头状瘤 (n =8) ,黏膜白斑 (n =9) ,声带上皮分化不良 (n =18) ,恶性肿瘤 (n =32 ) ,其他 6例。结论 :接触性内窥镜作为一种新的微创的辅助检查方法。

关键词：接触性内窥镜喉病变诊断临床应用喉癌癌前病变微创病理学检查

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EFNS急性卒中神经影像学指南EFNS特别工作组的报道

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国际脑血管病杂志 2007年第8期15卷 566-576页

作者： J.c. Masdeu P. Irimia S. Asenbaum J. Bogousslavsky M. Brainin H. chabriat K. Herholz H.S. Markus E. Martínez-Vila K. Niederkorn P.D. Schellinger R.J. Seitz 林曰增（译） From the Department of Neurology and Neurosurgery Uniuersity of Navarra Pamplona Spain Department of Neurology Medical University of Vienna Vienna Austria Department of Neurology Centre Hospitalier Universitaire Vaudois Lausanne Switzerland Department of Neurology Donauklinikum and Donau-Universitat Maria Gugging Austria Department of Neurology I.zriboisiere Hospital University of Paris Paris Frame Wolfson Molecular Imaging centre University of Manchester Manchester Department of Neurology and clinical Neuroscience St George＇s Hospital Medical School London UK Department of Neurology Karl Franzens University Graz Austria Department of Neurology University Clinic at Heidelberg Genmany arid Department of Neurology University Hosnital Düsseldorf Düsseldorf Germary 南军区青岛第一疗养院放射科青岛266071

神经影像学技术对于卒中的评价是必需的。在发达国家，卒中是死亡和神经功能缺损的前几位原因之一。可供使用的影像学技术的多样性增加了临床医师决策的复杂性。我们全面回顾了1965-2005年的英文文献并对相关出版物进行了严格评价。专... 详细信息

神经影像学技术对于卒中的评价是必需的。在发达国家，卒中是死亡和神经功能缺损的前几位原因之一。可供使用的影像学技术的多样性增加了临床医师决策的复杂性。我们全面回顾了1965-2005年的英文文献并对相关出版物进行了严格评价。专家组成员检查和修改了初稿，然后按照欧洲神经病学学会联盟（EFNS）标准，对分层推荐意见达成共识。cT平扫是卒中患者初步评价的一种固定的影像学检查。然而，MRI对于显示梗死或缺血区较cT更为敏感，而且还能显示急性和慢性脑出血。灌注和弥散MRI和磁共振血管成像（MRA）对缺血性卒中的急性期评价非常有用。对于脑动脉瘤的筛查以及脑静脉血栓形成和动脉夹层分离的诊断，MRI和MRA是推荐的影像学技术。对于颅外血管的无创性检查，MRA不如超声检查轻便且价格更加昂贵，但它对颈动脉狭窄的敏感性和特异性更高。经颅多普勒对于监测溶栓治疗后的动脉再灌注、诊断颅内血管狭窄和右向左分流以及监测蛛网膜下腔出血后的血管痉挛非常有用。目前，单光子发射体层摄影和正电子发射体层摄影在急性卒中患者评价中的作用非常有限。

关键词：计算机体层摄影 cT血管造影磁共振成像磁共振血管造影灌注卒中超声

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Accretion in strong field gravity with eXTP

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Science china(Physics,Mechanics & Astronomy) 2019年第2期62卷 45-73页

作者： Alessandra De Rosa Phil Uttley LiJun Gou Yuan Liu cosimo Bambi Didier Barret Tomaso Belloni Emanuele Berti Stefano Bianchi Ilaria caiazzo Piergiorgio casella Marco Feroci Valeria Ferrari Leonardo Gualtieri Jeremy Heyl Adam Ingram Vladimir Karas FangJun Lu Bin Luo Giorgio Matt Sara Motta Joseph Neilsen Paolo Pani Andrea Santangelo XinWen Shu JunFeng Wang Jian-Min Wang YongQuan Xue YuPeng Xu WeiMin Yuan YeFei Yuan Shuang-Nan Zhang Shu Zhang Ivan Agudo Lorenzo Amati Nils Andersson cristina Baglio Pavel Bakala Altan Baykal Sudip Bhattacharyya Ignazio Bombaci NiccolóBucciantini Fiamma capitanio Riccardo ciolfi Wei K.cui Filippo D'Ammando Thomas Dauser Melania Del Santo Barbara De Marco Tiziana Di Salvo chris Done Michal Dovciak Andrew c.Fabian Maurizio Falanga Angelo Francesco Gambino Bruce Gendre Victoria Grinberg Alexander Heger Jeroen Homan Rosario Iaria Jiachen Jiang chichuan Jin Elmar Koerding Manu Linares Zhu Liu Thomas J.Maccarone Julien Malzac Antonios Manousakis Frédéric Marin Andea Marinucci Missagh Mehdipour Mariano Méndez Simone Migliari cole Miller Giovanni Miniutti Emanuele Nardini Paul T.O'Brien Julian P.Osborne Pierre Olivier Petrucci Andrea Possenti Alessandro Riggio Jerome Rodriguez Andrea Sanna LiJing Shao Malgosia Sobolewska Eva Sramkova Abigail L.Stevens Holger Stiele Giulia Stratta Zdenek Stuchlik Jiri Svoboda Fabrizio Tamburini Thomas M.Tauris Francesco Tombesi Gabriel Torok Martin Urbanec Frederic Vincent QingWen Wu Feng Yuan Jean J.M.in't Zand Andrzej A.Zdziarski XinLin Zhou INAF-Istituto di Astrofisica e Planetologie Spaziali Via Fosso del Cavaliere Anton Pannekoek Institute for Astronomy University of Amsterdam National Astronomical Observatories Chinese Academy of Science Institute of High Energy Physics Chinese Academy of Science center for Field Theory and Particle Physics and Department of Physics Fudan University IRAP Universitéde ToulouseCNRSUPSCNES INAF-Osservatorio Astronomico di Brera Department of Physics and Astronomy The University of MississippiUniversity Dipartimento di Matematica e Fisica Universitàdegli studi Roma Tre University of British columbia INAF-Osservatorio Astronomico di Roma INFN-Roma 2 c/o Dipartimento di Fisica II Universit?di Roma"Tor Vergata" Dipartimento di Fisica Universitàdegli Studi di Roma"La Sapienza"&Sezione INFN Roma1 Department of Physics University of OxfordClarendon Laboratory Astronomical Institute Academy of Sciences School of Astronomy and Space Science Nanjing University MIT Kavli Institute for Astrophysics and Space Research Institut für Astronomie und Astrophysik Eberhard Karls Universität Department of Physics Anhui Normal University Department of Astronomy and Institute of Theoretical Physics and Astrophysics Xiamen University cAS Key Laboratory for Research in Galaxies and cosmology Department of AstronomyUniversity of Science and Technology of China Instituto de Astrofísica de Andalucia(cSIc) Glorieta de la Astronomía s/n INAF-Istituto di Astrofisica Spaziale e Fisica cosmica di Bologna Mathematical Sciences and STAG Research centre University of Southampton New York University Abu Dhabi Institute of Physics and Research centre for computational Physics and Data Processing Faculty of Philosophy&ScienceSilesian University in OpavaíBezru?ovo nám. Department of Physics Middle East Technical University Department of Astronomy and Astrophysics Tata Institute of Fundamental Research Dipartimento di Fisica Universit?di Pisa&INFN INAF-Osservatorio Astrofisico di Arcetri INAF-Osservatorio Astronomico di Padova INFN-TIFPA Trento Ins

In this paper we describe the potential of the enhanced X-ray Timing and Polarimetry(eXTP) mission for studies related to accretion flows in the strong field gravity regime around both stellar-mass and supermassive black-holes. eXTP has the unique capability of using advanced "spectral-timing-polarimetry" techniques to analyze the rapid variations with three orthogonal diagnostics of the flow and its geometry, yielding unprecedented insight into the inner accreting regions, the effects of strong field gravity on the material within them and the powerful outflows which are driven by the accretion process.

关键词： X-ray black holes physics accretion

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