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Hypertension and intracerebral hemorrhage in Brazzaville

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World Journal of Cardiovascular Diseases 2013年第9期3卷 523-528页

作者： Thierry Raoul Gombet Paul Macaire Ossou-Nguiet Thibaut Naibe Gankama Bertrand Fikahem Ellenga-Mbolla Gilbert Fabrice Otiobanda karen obondzo-aloba Benjamin Longo-Mbenza Department of Medicine Faculty of Health Sciences of Brazzaville Brazzaville Congo Service of Emergency University Hospital of Brazzaville Brazzaville Congo Department of Medicine Faculty of Health Sciences of Brazzaville Brazzaville CongoService of Cardiology University Hospital of Brazzaville Brazzaville Congo Department of Medicine Faculty of Health Sciences of Brazzaville Brazzaville CongoService of Neurology University Hospital of Brazzaville Brazzaville Congo Faculty of Health Sciences Walter Sisulu University Mthatha South Africa Service of Cardiology University Hospital of Brazzaville Brazzaville Congo Service of Neurology University Hospital of Brazzaville Brazzaville Congo Service of Reanimation University Hospital of Brazzaville Brazzaville Congo

Hypertension is not only an important risk factor, but also an important cause of spontaneous intracerebral hemorrhage. Its high prevalence in Africa reflects a high incidence of cerebral hemorrhage ranging from 30% to 60% against 10% to 20% in industrialized countries. The aim of our study was to determine the role of hypertension before the onset of intracerebral hemorrhage and its variations during the first three months. This was a longitudinal study conducted at the University Hospital of Brazzaville from 1st January to 31st August 2012 with all patients admitted for intracerebral hemorrhage. Patients with subarachnoid or pure intraventricular hemorrhage were excluded. The study variables were: history of hypertension, knowledge of its history, treatment, blood pressure on admission and during the first 3 months and the relationship between blood pressure and evolution. Statistical analysis was performed using the software SPSSS 16.1. The significance level was set at p < 0.05. During the study 261 patients were hospitalized for stroke, of which 82 (31.42%) were for intracerebral hemorrhage. The mean age was 55 ± 11 years and sex ratio of 2 men:1 woman. Hypertension was found in 80.5% of cases, of which 65.2% had known hypertension, but 82.6% had discontinued treatment. The mean systolic blood pressure was 194 ± 41 mm Hg and diastolic 104 ± 20 mm Hg. The location was deep in 85.71%. The normalization of blood pressure was obtained from the second week. After adjusting for confounders using logistic analysis, only uncontrolled hypertension was associated significantly and independently associated with a higher mortality rate (p = 0.042).

关键词： Hypertension Cerebral Hemorrhage Brazzaville

Impact of Tension-Type Headaches in the Workplace in Brazzaville

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Neuroscience & Medicine 2024年第2期15卷 77-91页

作者： Happhia Dinah Boubayi Motoula Latou Josué Euberma Diatewa Ghislain Armel Mpandzou Prince Eliot Galieni Sounga Bandzouzi Jean Brice Mouendenguia karen Lise obondzo aloba Paul Macaire Ossou-Nguiet Faculty of Health Sciences Universit Marien Ngouabi Brazzaville Congo Department of Neurology Brazzaville University Hospital Congo Department of Neurology Loandjili General Hospital Pointe-Noire Congo

Introduction: Tension-type headaches are the most widespread of the primary headache disorders. Due to their high prevalence, tension-type headaches represent a major public health problem with an enormous socio-economic burden. Determining their impact remains a challenge. Objective: To assess the impact of occupational tension-type headache in Brazzaville and identify associated factors. Population and Methods: This was an analytical case-control study conducted in public and private companies in the city of Brazzaville over a period of four (04) months. The case population consisted of cephalalgic employees;the control population was drawn from the same companies and was free of tension-type headaches. Study variables were divided into socio-professional, clinical and individual impact variables. Individual impact variables were represented by: the HIT-6 score, which incorporates a very broad conception of disability, covering several domains, namely: severity of pain during attacks and the restrictive and limiting nature of attacks. Results: Individual impact was severe in 18 (62.1%) men and 11 (37.9%) women. Mean age was 36.3 6.14 years for cases with severe impact. The mean duration of headache was 40.3 32.7 months for cases with severe impact. Tension headache evolved in attacks in 22 (75.9%) cases with severe impact, and continuously in seven (24.1%) cases. The average number of attacks per month was 2.52 1.04 for cases with severe impact. Cases with severe impact included 14 (48.3%) with chronic headache and 15 (51.7%) with episodic headache. Pain of severe intensity present in 48.3% of cases was associated with a severe impact of tension-type headache: OR = 151.66 [2.36 - 44245.95] and p-value = 0.037. At least one days absence from work per year was observed in 47.4% of our cases. The number of days off work per year due to tension-type headache had an interquartile range between 0 and 3 days and extremes from 0 to 14 days. It was the consequence of a sev

关键词： Impact Tension Headache Workplace

Mortality from Stroke in Young People in Brazzaville

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World Journal of Neuroscience 2024年第1期14卷 37-55页

作者： Motoula Latou Happhia Dinah Boubayi Josué Euberma Diatewa Ghislain Armel Mpandzou Prince Eliot Galieni Sounga Bandzouzi Elizeth Richtellah Fouti Kouapele karen Lise obondzo aloba Paul Macaire Ossou-Nguiet Faculty of Health Sciences Université Marien Ngouabi Brazzaville The Republic of the Congo Department of Neurology Brazzaville University Hospital Brazzaville The Republic of the Congo Department of Neurology Loandjili General Hospital Pointe-Noire The Republic of the Congo

Introduction: Cerebrovascular accidents (CVA) are an absolute neurovascular emergency and the main cause of mortality and acquired disability in adults. In the Congo, stroke is the leading cause of mortality and the leading cardiovascular emergency, with a hospital frequency of between 49.74% and 56.2%. The aim of the study was to identify the mortality factors associated with stroke in young people in Brazzaville. Patients and Methods: This is a longitudinal analytical study conducted from February to period from February to September 2019 in the neurology, general intensive care and medical emergency departments of the Brazzaville University Hospital (CHUB). All subjects aged 18 - 55 years of completed age, admitted for arterial stroke confirmed by brain imaging, were included. Study variables were: age, gender, socioeconomic level, laterality, time to admission and CT scan, vascular risk factors, history of cardiomyopathy, atrial fibrillation, TIA (transient ischemic attack) or stroke, NIHSS (National Institutes of Health Stroke Scale) score, Glasgow score, blood pressure, temperature, heart rate, occurrence or non-occurrence of complications, blood glucose, creatinine, lipid profile and blood count. Data were analyzed using SPSS 21 software. Descriptive analyses were performed using SPSS 21 software. Results: 103 patients were included in the study, of whom 45 (43.7%) had ischemic stroke and 58 (56.3%) with hemorrhagic stroke. Mortality was high at 29.1% in our study, and mainly concerned hemorrhagic strokes (73.7%). Two-week mortality in our study accounted for 63.33% of total lethality. After simple logistic regression, the factors associated with death within two weeks were age between 40 - 44 years (OR (odds ratio) = 2.95;p = 0.01), hemorrhagic stroke (OR = 1.41;p = 0.07), mass effect (OR = 3.26;p 15 (OR = 5.89 (2.90 - 11.95);p <

关键词： Brazzaville Mortality Stroke Young Subjects

Clinical and Therapeutic Aspects of Migraine in Brazzaville

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World Journal of Neuroscience 2024年第1期14卷 56-71页

作者： Motoula Latou Happhia Dinah Boubayi Josue Diatewa Prince Eliot Galieni Sounga Bandzouzi Ghislain Armel Mpandzou Héloïse Stéphanie Ongoly Ikora karen Lise obondzo aloba Paul Macaire Ossou-Nguiet Faculty of Health Sciences Marien Ngouabi University Brazzaville The Republic of the Congo Department of Neurology Brazzaville University Hospital Brazzaville The Republic of the Congo Department of Neurology Loandjili General Hospital Pointe-Noire The Republic of the Congo

Introduction: Migraine is the most common primary headache, and can cause significant disability. There are two types, migraine without aura and migraine with aura. The diagnosis of migraine is essentially clinical. Worldwide prevalence was estimated at 11.6% in 2009. In Africa, it is estimated at 10.4%. Objective: To describe the clinical and therapeutic aspects of migraine in Brazzaville. Patients and Methods: This was a door-to-door cross-sectional study conducted from 1st May to 1 st July 2018 in the city of Brazzaville. Subjects over 18 with clearly expressed consent were included. The questionnaire covered demographic characteristics, diagnostic criteria for migraine according to the IHS, treatments taken. The degree of disability was determined using the Migraine Disability Assessment Scale (MIDAS). Statistical analysis was performed using SPSS 22.0 for MAC. Results: Of the 1017 subjects interviewed in this study, 115 (39.9%) had migraine, including 73 women (63.47%) and 42 men (36.52%). In the group of migraine sufferers, the number of cases of definite migraine was 61 (53.04%) and that of probable migraine 54 (46.95%). For 81 migraine sufferers (70.43%), stress was the triggering factor. The frequency of attacks was weekly and monthly for 30 (26.1%) and 19 (16.5%) sufferers respectively. The location of the migraine was unilateral in 38% of cases and tilted in 24.3%. The intensity of the attack was described as moderate and severe in 41.7% and 57.4% of subjects respectively. Phonophobia/photophobia accompanied the migraine in 65.2% of cases. One hundred and eight subjects were treated. Of these, 106 (98.1%) were on medication. Eleven (10.37%) had received a medical prescription, and ninety-seven (89.8%) were self-medicating. Five and three subjects were under the care of a general practitioner and a neurologist respectively. Conclusion: Migraine is a frequent pathology in Brazzaville. Its preponderance among young people and women call

关键词： Migraine Clinic Therapeutics Brazzaville

What Strategy for a Severe Stroke in Africa: Palliative Care or Unreasonable Obstinacy?

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World Journal of Neuroscience 2020年第1期10卷 37-41页

作者： Paul Macaire Ossou-Nguiet Ghislain Armel Mpandzou Dinah Happhia Motoula Latou Josué Euberma Diatewa karen Lise Charmel obondzo aloba Prince Eliot Sounga Bandzouzi Bertrand Fikahem Ellenga Mbolla Faculty of Health Sciences of Brazzaville Brazzaville Congo Department of Neurology Brazzaville University Hospital Brazzaville Congo

Introduction: Palliative care, firstly used for chronic diseases, is currently indicated for some acute pathology such as Stroke. Its implementation improves the quality of care for end-of-life patients. The aim of our study is to report a series of patients who died in the intensive care stroke unit of Brazzaville. Method: It was a descriptive study of a series of 13 cases of severe stroke, admitted to the intensive care unit of the university hospital of Brazzaville, between January 2015 and December 2017. Sociodemographic, clinical, paraclinical and prognostic variables were studied. Result: The mean age of the patients was 46 ± 11.5 years with a male predominance in 69.2% (n = 9). They were all hypertensive. The motor deficit and consciousness disorder association was the reason for admission in 84.6% (n = 11) and an epileptic seizure of 15.4% (n = 2). The mean NIHSS at admission was 21 ± 5, that of Glasgow 6 ± 3. Stroke was hemorrhagic in 84.6% (n = 11) and malignant infarction in 15.4% (n = 2). All of these patients received invasive resuscitation with assisted ventilation and all died within 8 days of admission. Conclusion: The issue of limitation of care deserves to be debated, and is proposed on a case-by-case basis, in the face of a serious stroke. Therapeutic relentlessness is not only expensive, but also raises the problem of suffering of the individual at the end of life.

关键词： Severe Stroke Palliative Care Stroke Unit Africa

Post-Stroke Sexual Disorders and Its Real-Life Experience within Couples in Brazzaville

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World Journal of Neuroscience 2021年第1期11卷 22-33页

作者： Josué Euberma Diatewa Prince Eliot Galiéni Sounga Banzouzi Ghislain Armel Mpandzou Dinah Happhia Boubayi Motoula Latou Gabrielle-Gracia Ontsira karen L. obondzo aloba Anani Wanscels Sévérin Odzebe Paul Macaire Ossou-Nguiet Department of Neurology University Hospital of Brazzaville Brazzaville Congo Faculty of Health Sciences University Marien Ngouabi Brazzaville Congo Department of Neurology General Hospital of Loandjili Pointe Noire Congo Department of Urology University Hospital of Brazzaville Brazzaville Congo

Background: Post-stroke sequelae can have repercussions on the sexual life and relational life of patients and their partners. Objectives: To determine the frequencies of sexual disorders after a first stroke event;to identify the factors associated with sexual disorders;to explore the real-life experience of sexual disorders within couples. Methods: It was an analytical cross-sectional study, conducted on patients followed up for a first stroke and their partners. It was carried out at public and private hospitals in Brazzaville, Congo, during the period of patient follow-up, from May to September 2019 (5 months). The Female Sexual Function Index, International Index of Erectile Function 5 and interviews were used to describe sexual aspects. The real-life experience of couples was explored using standardized and pre-established questionnaires. Results: Of the 36 patients who had taken up again sexual intercourse after stroke, 29 (80.6%) were men. Among the post-stroke sexual disorders, erectile dysfunction (53.2%) and ejaculatory dysfunction (40.4%) were the most frequent in men. Decrease of sexual desire was predominant in women (100%). Factors associated with erectile dysfunction were sleep disorder (p = 0.007) and mean sleep duration per night (p = 0.01). Lack of verbal and non-verbal communication of sexual problems and psychological effects was noted in 77.8% of patients and 60% of their partners. The most frequent psychological effects were: in patients, frustration (52.8%), attitude of person decreased (50%) and sadness (41.7%);in partners, attitude of carer (86.7%). Conclusion: Post-stroke sexual disorders are frequent in our context. Sleep disorders and mean sleep duration per night, psychological

关键词： Post-Stroke Sexual Disorders Brazzaville

Spectrum of Neurological Disorders Related to Autoimmune Diseases in Brazzaville, Congo

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World Journal of Neuroscience 2023年第1期13卷 21-38页

作者： Josué Euberma Diatewa Ghislain Armel Mpandzou Rovalez Edgar Mouandza Ongouya Dinah Happhia Boubayi Motoula-Latou karen Lyse obondzo aloba Yacouba Kaba Régis Moyikoua Dominique Marline Nguiegna Estelle Boudzoumou Diakabana Eliot Prince Galiéni Sounga-Banzouzi Franck Ladys Banzouzi Paul Macaire Ossou-Nguiet Neurology Department University Teaching Hospital of Brazzaville Brazzaville Republic of Congo Faculty of Health Sciences Marien Ngouabi University Brazzaville Republic of Congo Radiology Department University Hospital Teaching of Brazzaville Brazzaville Republic of Congo Neurology Department Loandjili General Hospital Pointe Noire Republic of Congo

Background: Autoimmune diseases, which are among the leading causes of morbidity and mortality in the world, are pathologies caused by a dysfunction of the immune system. They can affect the central nervous system, the peripheral nervous system or both nervous systems. Objectives: To describe the epidemiological, clinical, paraclinical, therapeutic and evolutive aspects of neurological disorders related to autoimmune diseases. Methods: This was a prospective cohort study. It was carried out from 1 January 2015 to 31 December 2019 (5 years). It focused on patients aged 15 years and above, who were hospitalized or followed as ambulatory patients for neurological disorders related to autoimmune diseases in the neurology department of the university teaching hospital in Brazzaville. Results: Among the 41 patients who fulfilled inclusion criteria, there were 29 (70.73%) women and 12 (29.27%) men. The average age of patients was 38.3 ± 13.8 years. An increase in the frequency of neurological disorders related to autoimmune diseases was observed every year. The main neurological disorders were neuromyelitis optica spectrum disorders (n = 14;34.15%), acute polyradiculoneuropathies (n = 13;31.71%), chronic polyradiculoneuropathies (n = 4;9.75%) and acute disseminated encephalomyelitis (n = 3;7.31%). The treatments administered, which consisted of corticosteroids and immunosuppressive drugs, had significantly improved the vital prognosis and functional status of patients (p = 0.025). Conclusion: In our study population, neurological disorders related to autoimmune diseases are rare. The neurological clinico-pathological entities diagnosed are similar to those reported in the literature. The therapeutic approaches used improve the quality of life of patients.

关键词： Autoimmune Diseases Neurological Disorders Brazzaville

Cichlid fish visual systems: mechanisms of spectral tuning

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Integrative Zoology 2009年第1期4卷 75-86页

作者： karen CARLETON Department of Biology University of MarylandCollege ParkUSA

Hundreds of species of cichlid fishes have evolved in the Great Lakes of *** colorful fishes are known for their ecological ***,we discuss the diversity of their visual *** have seven unique cone opsin genes,which produce visual pigments sensitive from the ultraviolet to the red end of the *** species typically express three visual pigments to produce a trichromatic visual *** species differ in which sets of opsin genes they express,visual sensitivities can differ *** addition to the large visual pigment shifts from changing gene expression,cichlids can also more finely tune visual pigments through altera-tions in opsin amino acid *** of these tuning mechanisms likely play an important role in cichlid ecology and could contribute to the evolution of cichlid diversity through speciation.

关键词： cichlid fish opsin gene vision visual pigments.

VISUAL PROGRAMMING FOR BUILDING INFORMATION MODELING:ENERGY AND SHADING ANALYSIS CASE STUDIES

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Journal of Green Building 2015年第4期10卷 28-43页

作者： karen Kensek University of Southern California School of ArchitectureWatt Hall#204Los AngelesCA 90089-0291

INTRODUCTION Although visual programming is being broadly implemented in other disciplines,it has only relatively recently become an important supplement to three-dimensional modeling programs in the architecture,engineering,and construction ***,Grasshopper in conjunction with Rhino is a leading example of a visual programming environment that is strongly supported by a user community that is developing additional functionality,but Grasshopper does not yet work directly with building information modeling(BIM)*** is relatively new,but shows considerable promise in becoming a constructive tool to complement BIM,3D modeling,and analysis programs because it includes parametric geom-etries and works with Revit,a leading BIM software *** case studies are described:extensibility of Dynamo through the use of a building energy simu-lation package,controlling a virtual model’s response through light level sensors,and interactively updating shading components for a building facade based on solar *** demonstrate that one can work directly within building information models(BIM)using a visual programming language through updating component *** case studies demonstrate the feasibility of a workflow for sustain-able design simulations that is different than that more commonly used--having a separation between design and analysis models and using a neutral file format exchange such as IFC or gbXML to transfer *** visual programming languages are still a bit uncommon in the building industry,a short background is provided to place them within the tool set of other customizable tools that designers have been developing.

关键词： visual programming language VPL building information modeling BIM Dynamo Revit Grasshopper computational design