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Understanding academic clinicians' intent to treat pediatric obesity

World Journal of Clinical Pediatrics 2017年第1期6卷 60-68页

作者： Claudia Frankfurter Charles Cunningham Katherine M Morrison Heather Rimas karen bailey Faculty of Medicine University of Toronto Department of Psychiatry and Behavioral Neurosciences McM aster University Department of Pediatrics Mc Master University Division of Pediatric Surgery Department of SurgeryMc Master University

AIM To examine the extent to which the theory of planned behavior(TPB) predicts academic clinicians' intent to treat pediatric *** A multi-disciplinary panel iteratively devised a Likert scale survey based on the constructs of the TPB applied to a set of pediatric obesity themes.A cross-sectional electronic survey was then administered to academic clinicians at tertiary care centers across Canada from January to April *** statistics were used to summarize demographic and item agreement data.A hierarchical linear regression analysis controlling for demographic variables was conducted to examine the extent to which the TPB subscales predicted intent to treat pediatric *** A total of 198 physicians,surgeons,and allied healthprofessionals across Canada(British Columbia,Alberta,Manitoba,Saskatchewan,Nova Scotia,Ontario and Quebec) completed the *** step 1,demographic factors accounted for 7.4% of the variance in intent *** in step 2,demographic variables and TPB subscales predicted 56.9% of the variance in a measure of the intent to treat pediatric *** behavioral control,that is,confidence in one's ability to manage pediatric obesity,and subjective norms,congruent with one's context of practice,were the most significant predictors of the intent to treat pediatric *** and barriers did not predict the intent to treat pediatric obesity in this *** Enhancing self-confidence in the ability to treat pediatric obesity and the existence of supportive treatment environments are important to increase clinician's intent to treat pediatric obesity.

关键词： Pediatric obesity Therapeutics Intention Decision Making Behavior

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Crohn's disease genotypes of patients in remission vs relapses after infliximab discontinuation

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World Journal of Gastroenterology 2012年第36期18卷 5058-5064页

作者： Cathy Lu Alistair Waugh Robert J bailey Raeleen Cherry Levinus A Dieleman Leah Gramlich Kata Matic Mario Millan karen I Kroeker Daniel Sadowski Christopher W Teshima Dennis Todoruk Clarence Wong karen Wong Richard N Fedorak Division of Gastroenterology Zeidler Ledcor CenterUniversity of AlbertaEdmontonAB T6G 2X8Canada Division of Gastroenterology Royal Alexandra HospitalEdmontonAB T5H 3V9Canada Division of Gastroenterology Grey Nuns HospitalEdmontonAB T6L 5X8Canada Division of Gastroenterology Misericordia HospitalEdmontonAB T5R 4H5Canada

AIM： To investigate genetic differences between Crohn＇s disease （CD） patients with a sustained remission vs relapsers after discontinuing infliximab while in cortico- steroid-free remission. METHODS： Forty-eight CD patients received infliximab and were in full corticosteroid-free clinical remission but then discontinued infliximab for reasons other than a loss of response, were identified by review of an electronic database and charts. Infliximab-associated remis- sion was defined as corticosteroid-free plus normaliza- tion of clinical disease activity [CD activity index （CDAI）〈 150] during follow-up visits based on physician global assessments. A CD relapse （loss of infliximab-induced remission） was clinically defined as a physician visit for symptoms of disease activity （CDAI 〉 220） and a thera- peutic intervention with CD medication（s）, or a hospital- ization with complications related to active CD. Genetic analyses were performed on samples from 14 patients （n = 6 who had a sustained long term remission after stopping infliximab, n -- 8 who rapidly relapsed after stopping infliximab）. Nucleotide-binding oligomerization domain 2 （NOD2）/caspase activation recruitment do- main 15 （CARD15） polymorphisms （R702W, G908R and L1007fs） and the inflammatory bowel disease 5 （IBDS） polymorphisms （IGR2060a1 and IGR3081a1） were ana- lyzed in each group. RESULTS： Five single nucleotide polymorphisms of IBD5 and NOD2/CARD15 genes were successfully analyzed for all 14 subjects. There was no signifcant increase in frequency of the NOD2/CARD15 polymor- phisms （R702W, G908R and L1007fs） and the IBD5 polymorphisms （IGR2060al and IGR3081a1） in either group of patients; those whose disease relapsed rap- idly or those who remained in sustained long term remission following the discontinuation of infliximab. Nearly a third of patients in full clinical remission who stopped infliximab for reasons other than loss of re- sponse remained in sustained clinical remission, while two-thirds rel

关键词： Infliximab Anti-tumor necrosis factor alpha Crohn's disease Inflammatory bowel disease Genotype

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肯妮贝儿英国乐坛新宠

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广播歌选 2007年第4期 20-20页

作者： karen

“心烦意乱的黄梅季节听着肯妮贝儿(Corinne bailey Rae)的专辑,顿然如沐清泉般沁凉舒畅。她的声音温暖而慵懒,带点稚气的诉说着花样的年华,音符里跳跃着某些尚待发展的可能性,撩动着听者骨子底的某处。”林忆莲如是说。

关键词：英国乐坛广播电台可能性音乐风格美声推荐闪耀跳跃音符

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