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Prospective cohort study on facial profile changes in infants with Robin sequence and healthy controls

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World Journal of Pediatrics 2024年第6期20卷 581-589页

作者： Cornelia Wiechers Julian Sowula karen Kreutzer Christoph E.Schwarz Christina Weismann Michael Krimmel Christian F.Poets bernd Koos Department of Neonatology Tuebingen University HospitalCalwerstrasse 772076 TuebingenGermany Center for Cleft Lip Palate and Craniofacial MalformationsTuebingen University HospitalTuebingenGermany Department of Orthodontics Tuebingen University HospitalTuebingenGermany Department of Oral and Maxillofacial Surgery Tuebingen University HospitalTuebingenGermany

background Various conservative and surgical approaches exist to treat Robin sequence(RS),but their effects on facial profile and mandibular catch-up growth are unclear.A functional treatment concept,used in our centre for 25 years,includes an individualized palatal plate with a velo-pharyngeal extension and intensive feeding *** We performed a prospective study to objectively describe facial profiles in infants with RS treated with the above *** with isolated RS were admitted to our tertiary perinatal and national referral centre for craniofacial malformations between May 2018 and Nov *** with RS received 3D-photographs during clinically indicated *** controls were recruited from Dec 2018 to Sep 2019 and received 3D-photographs every 3 *** digitally measured jaw index(JI),defined as alveolar overjet(O)x maxillary arch(U)/mandibular arch(L),and the soft tissue reference points A’-point,Nasion’,b’-point angle(ANb’),describing the relative position of maxilla to mandible,were *** mixed models were used to examine time trajectories in JI and ANb’.Results A total of 2073D images,obtained in 19 infants with RS and 32 controls,were *** and ANb’decreased over time in both groups[for JI−0.18(95%CI−0.25 to−0.10);for ANb’:−0.40°per month[(95%CI−0.48 to−0.32)]]but remained lower in controls[for JI−2.5(95%CI−3.2 to−1.8);for ANb’-1.7°(95%CI−2.4 to−1.0)].Also,the ANb’model showed a significant effect of the interaction term diagnosis x *** based on longitudinal 3D images,we describe changes in objective parameters of facial profile in infants with and without RS during the first year of *** findings indicate catch-up growth in infants treated for RS.

关键词： Infant Mandibular catch-up growth Pre-epiglottic baton Plate Robin sequence Three-dimensional photography

Impact of exercise on markers of b cell-related immunity:A systematic review

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Journal of Sport and Health Science 2024年第3期13卷 339-352,I0002页

作者： David Walzik Sergen belen karen Wilisch Marie Kupjetz Silvana Kirschke Tobias Esser Niklas Joisten Alexander Schenk Sebastian Proschinger Philipp Zimmer Division of Performance and Health(Sports Medicine) Institute for Sport and Sport ScienceTU Dortmund UniversityDortmund 44227Germany

background:b cells represent a crucial component of adaptive immunity that ensures long-term protection from infection by generating pathogen-specific *** alters b cell counts and immunoglobulin levels,but evidence-based conclusions on potential benefits for adaptive immunity are *** systematic review assessed current literatures on the impact of acute exercise and exercise training on b cells,immunoglobulins,and markers of secretory immunity in human ***:According to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses(PRISMA)guidelines,MEDLINE,Web of Science,and Embase were searched on March 8,***-randomized controlled trials and crossover trials investigating the impact of acute exercise or exercise training on b cell counts and proportions,immunoglobulin levels,salivary flow rate,or secretory immunoglobulin A secretion rate were *** and reporting of exercise training studies were assessed using the Tool for the Assessment of Study Quality and reporting in *** characteristics,outcome measures,and statistically significant changes were summarized ***:Of the 67 eligible studies,22 applied acute exercise and 45 applied exercise *** included outcomes revealed significant alterations over time in acute exercise and exercise training context,but only a few investigations showed significant differences compared to control *** and plasma immunoglobulin A levels were most consistently increased in response to exercise ***:b cell-related outcomes are altered by acute exercise and exercise training,but evidence-based conclusions cannot be drawn with high confidence due to the large heterogeneity in populations and exercise ***-designed trials with large sample sizes are needed to clarify how exercise shapes b cell-related immunity.

关键词： Antibody b-lymphocyte Exercise Humoral immunity Immune system

Depositional condition of Paleoproterozoic Francevillian carbonate rocks revisited from rare earth element contents

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Geoscience Frontiers 2024年第3期15卷 31-49页

作者： Satoshi Yoshida karen bakakas Mayika Yuki Ishihara Mathieu Moussavou Hisashi Asanuma Tomohiko Sato Takafumi Hirata Cédric Ligna Yusuke Sawaki Amboise Edou-Minko Department of Earth Science and Astronomy The University of Tokyo3-8-1 Komaba Meguro-kuTokyo 153-8902Japan Center for Northeast Asian Studies Tohoku University41 KawauchiAoba-kuSendai 980-8576Japan Department of Geology Universitédes Sciences et Techniques de MasukuBP:90190025 FrancevilleGabon Department of Earth and Planetary Science The University of Tokyo7-3-1 HongoBunkyo-kuTokyo 113-0033Japan Geochemical Research Center The University of Tokyo7-3-1HongoBunkyo-kuTokyo 113-0033Japan Graduate School of Human and Environmental Studies Kyoto UniversityYoshida-nihonmatsuSakyo-kuKyoto 606-8501Japan Center for Fundamental Education Okayama University of Science1-1Ridai-choKita-kuOkayama CityOkayama 700-0005Japan

The Paleoproterozoic Francevillian Group in the eastern Gabonese Republic has been recently attracting increasing attention because it includes distinctive macroscopic structures interpreted as eukaryotic ***,its depositional setting and associated redox conditions need to be clearly *** clarify these,petrological studies and rare earth element(REE)abundances of carbonate rocks of the Francevillian Group in the Lastoursville basin were determined with ICP-MS coupled with a laser ablation sampling *** microscopic observations indicate that dolostones in this basin underwent the complicated diagenetic history,including sparitization,decomposition of organic matter,reduction of ferromanganese oxides,silicification,and later *** dolostones of lower Francevillian b(Fb)Formation show heterogeneous textures formed by alterations during *** the alterations,changes of REE abundances and degrees of positive Y anomalies appear to have *** indicates that REE signatures in carbonate rocks can vary during *** high Mn contents in the dolostones of upper Fb Formation were derived from the reduction of ferromanganese oxides in *** signatures of REE abundance in dolostones can be explained by the mixing of seawater and ferromanganese oxide *** that sense,the dolostones inherited the trace element characteristics of precursor ferromanganese oxides even after the diagenesis.Y/Ho values of the most primary parts of each sample exceed 33,the newly determined threshold value for marine carbonate rocks based on our *** magnitude of the La anomaly values also falls within the range of that of Holocene reefal *** indicate that a precursor of the dolostone of the Francevillian Group was deposited in a marine *** addition,presence of Ce anomalies in the upper Fb Formation suggests that the Paleoproterozoic ocean was oxidized to such an ex

关键词： Carbonate diagenesis Francevillian Group LA-ICP-MS Seawater composition Y/Ho fractionation

Confirmation of a Sub-Saturn-size Transiting Exoplanet Orbiting a G Dwarf:TOI-1194 b and a Very Low Mass Companion Star: TOI-1251 b from TESS

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Research in Astronomy and Astrophysics 2024年第3期24卷 129-143页

作者： Jia-Qi Wang Xiao-Jun Jiang Jie Zheng Hanna Kellermann Arno Riffeser Liang Wang karen A.Collins Allyson bieryla Lars A.buchhave Steve b.Howell Elise Furlan Eric Girardin Joao Gregorio Eric Jensen Felipe Murgas Mesut Yilmaz Sam Quinn Xing Gao Ruo-Yu Zhou Frank Grupp Hui-Juan Wang CAS Key Laboratory of Optical Astronomy National Astronomical ObservatoriesChinese Academy Of SciencesBeijing 10010China University of Chinese Academy of Sciences Beijing 100049China University Observatory Munich Scheinertrsse 1.D-81679 MunichGemany Max Planck Institute for Extraterrestrial Physics Giessenbachstr.1D-85748 GarchingGermany National Astronomical Observatories/Nanjing Institute of Astronomical Optics&Technology Chinese Academy of SciencesNanjing210042China CAS Key Laboratory of Astronomical Optics&Technology Nanjing Institute of Astronomical Optics&TechnologyNanjing 210042China Center for Astrophysics Harvard&Smithsonian60 Garden Street.CambridgeMA 02138USA National Space Institute Technical University of DenmarkElektrovejDK-2800 KgsLyngbyDenmark NASA Ames Research Center Moffett FieldCA 94035USA NASA Exoplanet Science Institute Caltech/IPACMail Code 100-221200 E.California Blvd.PasadenaCA91125USA Grand Pra Observatory Switzerland Department of Physics Washington UniversitySt.LouisMO 63130.USA Department of Physics and Astronomy Swarthmore CollegeSwarthmorePA 19081USA Instituto de Astrofísica de Canarias(IAC) E-38205 La Laguna.TenerifeSpain Departamento de Astrofísica Universidad de La LagunaSpain Dept.of Astronomy and Space Sciences Ankara UniversityTandogan 06100AnkaraTurkey Xinjiang Astronomical Observatory Chinese Academy of SciencesUrumqi 830011China Urumqi No.1 Senior High School Urumqi 830002China Lijiang Gemini Observatory Lijiang 674199China

We report the confirmation of a sub-Saturn-size exoplanet,TOI-1194 b,with a mass of about 0.456+0.055-0.051M_(J),and a very low mass companion star with a mass of about 96.5±1.5 MJ,TOI-1251 *** candidates provided by the Transiting Exoplanet Survey Satellite(TESS)are suitable for further follow-up observations by ground-based telescopes with small and medium *** analysis is performed based on data from several telescopes worldwide,including telescopes in the Sino-German multiband photometric campaign,which aimed at confirming TESS Objects of Interest(TOIs)using ground-based small-aperture and medium-aperture telescopes,especially for long-period ***-1194 b is confirmed based on the consistent periodic transit depths from the multiband photometric *** measure an orbital period of 2.310644±0.000001 days,the radius is 0.767+0.045-0.041RJ and the amplitude of the RV curve is 69.4_(-7.3)^(+7.9)m s^(-1).TOI-1251 b is confirmed based on the multiband photometric and high-resolution spectroscopic data,whose orbital period is 5.963054+0.000002-0.000001days,radius is 0.947+0.035-0.033 R_(J) and amplitude of the RV curve is 9849_(-40)^(+42)ms^(-1).

关键词： planets and satellites fundamental parameters-planets and satellites gaseous planets-stars fundamental parameters-stars low-mass-methods data analysis-techniques photometric-techniques spectroscopic

A novel diagnostic gene region for distinguishing between two pest fruit flies:bactrocera tryoni(Froggatt)and bactrocera neohumeralis(Hardy)(Diptera:Tephritidae)

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Insect Science 2024年第4期31卷 1285-1295页

作者： Melissa L.Starkie Elizabeth V.Fowler Alexander M.Piper Xiaocheng Zhu Pauline Wyatt David Gopurenko Matt N.Krosch Francesca Strutt karen F.Armstrong Hamish Patrick Mark K.Schutze Mark J.blacket Department of Agriculture and Fisheries BiosecurityBrisbaneQueenslandAustralia Agriculture Victoria AgriBioBundooraVictoriaAustralia Department of Primary Industries Wagga Wagga Agricultural InstituteWagga WaggaNew South WalesAustralia Forensic Services Group Queensland Police ServiceBrisbaneQueenslandAustralia Department of Pest-management and Conservation Lincoln UniversityLincolnNew Zealand better border biosecurity(b3 B3nz.org.nz)LincolnNew Zealand

bactrocera tryoni and bactrocera neohumeralis are morphologically similar sibling pest fruit fly species that possess different biological attributes,geographic distributions,and host *** need to differentiate between the two species is critical for accurate pest status assessment,management,biosecurity,and maintenance of reference *** morphologically similar,adults may be separated based on subtle characters;however,some characters exhibit intraspecific variability,creating overlap between the two ***,there is currently no single molecular marker or rapid diagnostic assay that can reliably distinguish between *** and ***;therefore,ambiguous samples remain *** we report the first molecular marker that can consistently distinguish between *** and *** diagnostic region consists of two adjacent single nucleotide polymorphisms(SNPs)within the pangolin(pan)gene *** confirmed the genotypes of each species are consistent across their distributional range,then developed a tetra-primer amplification refractory mutation system(ARMS)PCR assay for rapid diagnosis of the *** assay utilizes four primers in multiplex,with two outer universal primers,and two internal primers:one designed to target two adjacent SNPs(AA)present in *** and the other targeting adjacent SNPs present in ***(GG).The assay accurately discriminates between the two species,but their SNP genotypes are shared with other nontarget tephritid fruit fly ***,this assay is most suited to adult diagnostics where species confirmation is necessary in determining ambiguous surveillance trap catches;maintaining pure colony lines;and in Sterile Insect Technique management responses.

关键词： ARMS-PCR colony molecular diagnostics pangolin tetra-primer

Insights into social relationships among female black howler monkeys Alouatta pigra at Palenque National Park, Mexico

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Current Zoology 2011年第1期57卷 1-7页

作者： Sarie VAN bELLE Alejandro ESTRADA karen b. STRIER Department of Zoology University of Wisconsin-Madison USA Estaclon de blologla Tropical Los Tuxtlas Instituto de Biologfa Universidad Nacional Autonoma de Mexico Mexico Department of Anthropology University of Wisconsin-Madison USA

Abstract We investigated the social relationships among adult females in two multimale-multifemale groups of black howler monkeys Alouatta pigra during a 14-month study in Palenque National Park, Mexico. based on over 900 focal hours and over 5400 scan samples recording neighboring group members, we found that females very rarely engaged in agonistic interactions and no dominance hierarchy could be discerned. Relationships among resident females were primarily affiliative, but females of one study group spent a higher proportion of time in close proximity and engaged in affiliative interactions with one another at higher rates than females in the other study group. The strength of female relationships increased with the birth of an infant. Al- though no females immigrated during the study period, the temporary association of three extragroup females with our study groups implies that the social system of black howler monkeys is more dynamic than previously suggested. These findings sug- gest that female black howler monkeys behave more similarly to female red howler monkeys A. seniculus than to female mantled howler monkeys A. palliata

关键词： black howler monkey Alouatta pigra Affiliation Agonism Female dispersal

Right time, right place: The dynamic role of hormones in rhizobial infection and nodulation of legumes

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Plant Communications 2022年第5期3卷 5-18页

作者： karen Velandia James b.Reid Eloise Foo Discipline of biological Sciences School of Natural SciencesUniversity of TasmaniaPrivate Bag 55HobartTAS 7001Australia

Many legume plants form beneficial associations with rhizobial bacteria that are hosted in new plant rootorgans, nodules, in which atmospheric nitrogen is fixed. This association requires the precise coordinationof two separate programs, infection in the epidermis and nodule organogenesis in the cortex. There isextensive literature indicating key roles for plant hormones during nodulation, but a detailed analysis ofthe spatial and temporal roles of plant hormones during the different stages of nodulation is *** review analyses the current literature on hormone regulation of infection and organogenesis to revealthe differential roles and interactions of auxin, cytokinin, brassinosteroids, ethylene, and gibberellins during epidermal infection and cortical nodule initiation, development, and function. With the exception ofauxin, all of these hormones suppress infection events. by contrast, there is evidence that all of these hormones promote nodule organogenesis, except ethylene, which suppresses nodule initiation. This differential role for many of the hormones between the epidermal and cortical programs is striking. Future work isrequired to fully examine hormone interactions and create a robust model that integrates this knowledgeinto our understanding of nodulation pathways.

关键词： auxin brassinosteroids cytokinin ethylene gibberellin nodulation

2023年美国麻醉医师学会神经肌肉阻滞监测与拮抗实践指南:美国麻醉医师学会工作组关于神经肌肉阻滞的报告

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中华麻醉学杂志 2024年第5期44卷 518-542页

作者： Stephan R.Thilen Wade A.Weigel Michael M.Todd Richard P.Dutton Cynthia A.Lien Stuart A.Grant Joseph W.Szokol Lars I.Eriksson Myron Yaster Mark D.Grant Madhulika Agarkar Anne M.Marbella Jaime F.blanck karen b.Domino 西雅图华盛顿州明尼阿波里斯明尼苏达州达拉斯得克萨斯州密尔沃基威斯康星州教堂山北卡罗来纳州洛杉矶加利福尼亚州斯德哥尔摩瑞典丹佛科罗拉多州绍姆堡伊利诺斯州巴尔的摩马里兰州

本实践指南基于证据提供了全身麻醉期间及术后神经肌肉功能监测与阻滞拮抗的管理推荐。主要关注神经肌肉功能监测的类型与部位及阻滞拮抗的过程,以减少肌肉松弛药残留阻滞。

关键词：神经肌肉阻滞肌肉松弛药神经肌肉功能监测舒更葡糖钠新斯的明

Prenatal Diagnosis of an Apically Located Congenital Left Ventricular Aneurysm: A Rare Case

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Congenital Heart Disease 2024年第1期19卷 123-129页

作者： Yücel Kaya And Yavuz Hasan berkan Sayal büşra Tsakir Gökalp Kabacaoğlu Kadriye NilayÖzcan Department of Perinatology Antalya Education and Research HospitalUniversity of Health SciencesAntalyaTurkey Department of Perinatology Faculty of MedicineSüleyman Demirel UniversityIspartaTurkey

Congenital ventricular aneurysm is a very rare cardiac anomaly.A diagnosis can be made during the prenatal period using fetal *** study presents a very rare apically located left ventricular aneurysm case,and the relevant literature was reviewed and *** this case,a 35-year-old,gravida 2,parity 1 preg-nant woman at 24 weeks of gestation,displayed a wide aneurysmal image in the left ventricular apical wall on fetal *** was a 1.79 mm muscular ventricular septal defect at the apical region of the interven-tricular *** the course of the color Doppler ultrasonography examination,an aberrantﬁbrous band within the left ventricle and consequent turbulentﬂow during systole were *** baby,born via cesarean section at 37 weeks of gestation,is now in its postnatal seventh ***,during echocardiographic follow-ups,changes have been observed,including mild to moderate mitral insufﬁciency and a decrease in systolic *** theseﬁndings,the clinical condition remains *** is of great importance to use a multidis-ciplinary approach in managing these rare cases that could lead to potential adverse outcomes during the antena-tal or postnatal periods.

关键词： Heart aneurysm prenatal diagnosis echocardiography congenital heart defects left ventricle