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Oral manifestations of hepatitis C virus infection

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World Journal of Gastroenterology 2014年第24期20卷 7534-7543页

作者： Marco Carrozzo kara Scally Centre for Oral Health Research Oral Medicine DepartmentUniversity of Newcastle upon TyneNewcastle upon Tyne NE2 4BWUnited Kingdom

Extrahepatic manifestations (EHMs) of hepatitis C virus (HCV) infection can affect a variety of organ systems with significant morbidity and mortality. Some of the most frequently reported EHM of HCV infection, involve the oral region predominantly or exclusively. Oral lichen planus (OLP) is a chronic inflammatory condition that is potentially malignant and represents cell-mediated reaction to a variety of extrinsic antigens, altered self-antigens, or super antigens. Robust epidemiological evidence support the link between OLP and HCV. As the virus may replicate in the oral mucosa and attract HCV-specific T lymphocytes, HCV may be implicated in OLP pathogenesis. Sjögren syndrome (SjS) is an autoimmune exocrinopathy, characterized by dryness of the mouth and eyes and a multitude of other systemic signs and symptoms. SjS patients have also an increased risk of non-Hodgkin lymphoma. Patients with chronic hepatitis C do frequently have histological signs of Sjögren-like sialadenitis with mild or even absent clinical symptoms. However, it is still unclear if HCV may cause a disease mimicking SjS or it is directly responsible for the development of SjS in a specific subset of patients. Oral squamous cell carcinoma is the most common oral malignant tumour and at least in some part of the world could be linked to HCV.

关键词： Hepatitis C virus Lichen planus Oral lichen planus Sjogren’ s syndrome Sialadenitis Oral squamous cell carcinoma

Diagnostic and prognostic significance of the lymphocyte/C-reactive protein ratio,neutrophil/lymphocyte ratio,and D-dimer values in patients with COVID-19

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BIOCELL 2022年第12期46卷 2625-2635页

作者： ALPASLAN OZTURK MEHMET kara Department of Medical Biochemistry Amasya University Faculty of MedicineAmasya05000Turkey Department of Infectious Diseases and Clinical Microbiology Beylikduzu State HospitalIstanbul34000Turkey

In this study,our aim was to examine the diagnostic and prognostic significance of lymphocyte/C-reactiveprotein ratio(LCR),neutrophil/lymphocyte ratio(NLR)and D-dimer parameters in COVID-19 *** LCR,NLR,neutrophil count,mean platelet volume(MPV),C-reactive protein(CRP),and D-dimer parameters wereevaluated *** was a retrospective cohort study with 1000 COVID-19 positive and 1000 healthycontrol groups,all over the age of 18 *** ratio(OR)and 95%confidence interval(CI)values were calculatedfor each parameter found to be statistically significant in the univariate and multivariate logistic regression ***,127(12.7%)of the COVID-19^(+)patients,whose data was included in this study,*** neutrophil,MPV,CRP,D-dimer,and NLR values were higher in the COVID-19^(+)/deceased group than in the COVID-19^(+)/alive andcontrol groups(p<0.001,p<0.001,p<0.001,p<0.001,p<0.001).The lymphocyte and LCR values were lower inthe COVID-19^(+)/deceased group than in the COVID-19^(+)/alive and control groups(p<0.001,p<0.001).Variableswith statistically significance in predicting COVID-19 infection were lymphocyte,LCR,D-dimer,NLR,CRP,MPV,PLT,and neutrophil *** significant variables in predicting mortality due to COVID-19 were LCR,CRP,NLR,lymphocyte,D-dimer,neutrophil,and MPV values.A low LCR and high NLR are associated with thepresence,prognosis,and mortality due to *** and NLR parameters can thus be used in clinicalmonitoring to reduce morbidity and mortality rates.

关键词： COVID-19 Lymphocyte/C-reactive protein ratio Neutrophil/lymphocyte ratio D-dimer Inflammation

A New Privacy-Preserving Data Publishing Algorithm Utilizing Connectivity-Based Outlier Factor and Mondrian Techniques

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Computers, Materials & Continua 2023年第8期76卷 1515-1535页

作者： Burak Cem kara Can Eyüpoglu Department of Computer Engineering Turkish Air Force AcademyNational Defence UniversityYesilyurtIstanbulTurkey Department of Computer Engineering Atatürk Strategic Studies and Graduate InstituteNational Defence UniversityBesiktasIstanbulTurkey

Developing a privacy-preserving data publishing algorithm that stops individuals from disclosing their identities while not ignoring data utility remains an important goal to *** finding the trade-off between data privacy and data utility is an NP-hard problem and also a current research *** existing approaches are investigated,one of the most significant difficulties discovered is the presence of outlier data in the *** data has a negative impact on data ***,k-anonymity algorithms,which are commonly used in the literature,do not provide adequate protection against outlier *** this study,a new data anonymization algorithm is devised and tested for boosting data utility by incorporating an outlier data detection mechanism into the Mondrian *** connectivity-based outlier factor(COF)algorithm is used to detect *** is selected because of its capacity to anonymize multidimensional data while meeting the needs of real-world ***,on the other hand,is used to discover outliers in high-dimensional datasets with complicated *** proposed algorithm generates more equivalence classes than the Mondrian algorithm and provides greater data utility than previous algorithms based on *** addition,it outperforms other algorithms in the discernibility metric(DM),normalized average equivalence class size(Cavg),global certainty penalty(GCP),query error rate,classification accuracy(CA),and F-measure ***,the increase in the values of theGCPand error ratemetrics demonstrates that the proposed algorithm facilitates obtaining higher data utility by grouping closer data points when compared to other algorithms.

关键词： Data anonymization privacy-preserving data publishing k-anonymity generalization mondrian

An Analysis of the Invariance and Conservation Laws of Some Classes of Nonlinear Ostrovsky Equations and Related Systems

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Chinese Physics Letters 2011年第1期28卷 1-4页

作者： K. Fakhar A. H. kara Department of Mathematics Faculty of Science Universiti Teknologi Malaysia 81310 UTM Skudai Johor Malaysia School of Mathematics and Centre for Differential Equations Continuum Mechanics and Applications University of the Witwatersrand Johannesburg P Bag 3 Wits 2050 South Africa

A large class of partial differential equations in the modelling of ocean waves are due to Ostrovsky. We determine the invariance properties （through the Lie point symmetry generators） and construct classes of conservation laws for some of the models. In the latter case, the method involves finding the ＇multipliers＇ associated with the conservation laws with a stronger emphasis on the ＇higher-order＇ ones. The relationship between the symmetries and conservation laws is investigated by considering the invariance properties of the multipliers.

关键词： Mathematical physics Statistical physics and nonlinear systems

Group Analysis, Fractional Explicit Solutions and Conservation Laws of Time Fractional Generalized Burgers Equation

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Communications in Theoretical Physics 2018年第1期69卷 5-8页

作者： Gang-Wei Wang A. H. kara School of Mathematics and Statistics Hebei University of Economics and Business Shijiazhuang 050061 China School of Mathematics University of the Witwatersrand Private Bag 3 Wits 2050 Johannesburg South Afric

The generalized fractional Burgers equation is studied in this paper. Using the classical Lie symmetry method, all of the vector fields and symmetry reduction of the equation with nonlinearity are constructed. In particular, an exact solution ＆ provided by using the ansatz method. In addition, other types of exact solution are obtained via the invariant subspace method. Finally, conservation laws for this equation are derived.

关键词： time fractional generalized Burgers equation Lie symmetry method explicit solutions conservation laws

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Effects of stand types on recreational preferences of society in the Sub-Alpine Zone,northern Turkey

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Journal of Mountain Science 2022年第11期19卷 3246-3256页

作者： Tuğrul VAROL Halil BarışÖZEL Ferhat kara İlkimÇAVUŞkara Sezgin AYAN Bartın University Faculty of ForestryDepartment of Forest EngineeringBartın 74100Turkey Kastamonu University Faculty of ForestryDepartment of Forest EngineeringKastamonu 37150Turkey Kastamonu-Ilgaz Mountain National Park Directorate Kastamonu 37100Turkey

The main objective of this study was to examine how different stand types influenced the tendency of visitors for varying recreational activities(i.e.,hiking,trekking,camping and hunting)from 1993 to 2018 in the surrounding areas of Uluyayla Natural Recreation Site in Bart1n,northern Turkey.A total of 627 visitors were selected on a voluntary basis,and questioned in the form of *** of the participants were in the age of 21-40 years old,and they were mostly(62.4%)*** of the participants(82.7%)lived in cities,while 62.8%of them were tourists when visiting the *** determining the preferences of the visitors regarding the stand types for different recreational activities,several images of each stand were shared with them,and they were asked which stand type they would prefer for a given recreation activity(i.e.,hiking,tracking,camping and hunting).A range of options from 1 to 5 in Likert's scale was used in evaluating the given *** degree of positive and negative effects was examined via trend *** was found that stand type had influence on the preferences of visitors regarding the recreational *** general,unmanaged and moderately treated stands were more preferred by visitors for the recreational purposes,compared to the previously managed *** the other hand,visitors'preference for the activities were different during two periods(i.e.,1993-2005 and 2006-2018).For each recreational activity,there was an increasing trend from 1993 to *** had been a continuous increase for hunting since 1996,and for trekking and camping after *** increases between 1993-1996 and 1996-1999 were likely due to the increasing awareness of the society as a result of the training and consciousness raising activities for nature *** demand on the recreational activities continuously increased in unmanaged and moderately treated stands,while no significant changes were examined in the previously managed *** st

关键词： Camping Hunting National Park Recreation Subalpine Silviculture

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A Galerkin-Type Fractional Approach for Solutions of Bagley-Torvik Equations

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Computer Modeling in Engineering & Sciences 2020年第6期123卷 941-956页

作者： Şuayip Yüzbaşı Murat karaçayır Department of Mathematics Akdeniz UniversityAntalya07070Turkey

In this study,we present a numerical scheme similar to the Galerkin method in order to obtain numerical solutions of the Bagley Torvik equation of fractional order 3/*** this approach,the approximate solution is assumed to have the form of a polynomial in the variable t=xα,whereαis a positive real parameter of our *** problem is firstly expressed in vectoral form via substituting the matrix counterparts of the terms present in the *** taking inner product of this vector with nonnegative integer powers of t up to a selected positive parameter N,a set of linear algebraic equations is *** incorporation of the boundary conditions,the approximate solution of the problem is then computed from the solution of this linear *** present method is illustrated with two examples.

关键词： Bagley-Torvik equation fractional derivative Galerkin method numerical solutions.

Investigation of hearing aid users'speech understanding in noise and their spectral-temporal resolution skills

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Journal of Otology 2023年第3期18卷 146-151页

作者： Mert Kılıç Eyyup kara Istanbul University-Cerrahpas¸a Institute of Graduate StudiesDepartment of AudiologyIstanbulTurkey Istanbul University-Cerrahpas¸a Faculty of Health SciencesDepartment of AudiologyIstanbulTurkey

Purpose:Our study aims to compare speech understanding in noise and spectral-temporal resolution skills with regard to the degree of hearing loss,age,hearing aid use experience and gender of hearing aid ***:Our study included sixty-eight hearing aid users aged between 40-70 years,with bilateral mild and moderate symmetrical sensorineural hearing *** gap detection test,Turkish matrix test and spectral-temporally modulated ripple test were implemented on the participants with bilateral hearing *** test results acquired were compared statistically according to different variables and the correlations were ***:No statistically significant differences were observed for speech-in-noise recognition,spectraltemporal resolution among older and younger adults in hearing aid users(p>0.05).There wasn’t found a statistically significant difference among test outcomes as regards different hearing loss degrees(p>0.05).Higher performances were obtained in terms of temporal resolution in male participants and participants with more hearing aid use experience(p<0.05).Significant correlations were obtained between the results of speech-in-noise recognition,temporal resolution and spectral resolution tests performed with hearing aids(p<0.05).Conclusion:Our study findings emphasized the importance of regular hearing aid use and it showed that some auditory skills can be improved with hearing *** of correlations among the speechin-noise recognition,temporal resolution and spectral resolution tests have revealed that these skills should be evaluated as a whole to maximize the patient’s communication abilities.

关键词： Hearing aids Speech in noise Spectral resolution Speech intelligibility Temporal resolution

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Impacts of urban headwater disturbances on downstream sediment loading where streamside management zones for forest harvesting activities are present downstream

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International Journal of Sediment Research 2017年第4期32卷 555-563页

作者： Ilkim Cavus Latif Kalin Ferhat kara Ministry of Forestry and Water Affairs.General Directorate of Combating Desertification and Erosion Auburn University School of Forestry and Wildlife Sciences Kastamonu University Faculty of Forestry

Watershed disturbances caused by land use/land cover(LU/LC) change, intensive forestry practices, and other forms of watershed disturbance are known to negatively affect water quality, if best management practices(BMPs) are not present. Disturbances near or around headwaters where BMPs are absent or are inadequate may impact downstream water quality and stream ecology regardless of the presence of downstream BMPs. In this study, the recovery of two small forest-dominated watersheds(Ww and Ew) in Auburn, Alabama, USA, was monitored 6-years after a partial clearcut was done. The streamside management zone(SMZ) in Ww was also partially harvested shortly after the partial clearcut to improve its sediment trapping effectiveness over the long-term. The hydrology and sediment transport in these watersheds were expected to stabilize over this period, however, new disturbances in the headwaters of both watersheds changed the watershed dynamics. Streamflow and sediment load were examined over a15-month period from February 2014 to May 2015. The clearcut in Ww and Ew, and the partially harvested SMZ in Ww seemed to have recovered; however, substantial amount of sediment load were measured across all monitoring sites in both watersheds as a result of upstream disturbances. This study emphasizes the necessity of watershed management as a whole, and the importance of BMP applications within the entire watershed. It also highlights the fact that watershed management and BMP implementation is a dynamic process, thus, strategies and techniques need to be continuously adapted in response to environmental changes.

关键词： Headwater disturbances Best management practices Sediment load Southeast USA