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Investig.ting.m.ller g.ia reprog.am.ing.in m.ce: a retrospective of the last decade, and a look to the future

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Neural Reg.neration Research 2025年第4期20卷 946-959页

作者： Zhiyuan Yin Jiahui kang Xuan Cheng.Hui g.o Shujia Huo Haiwei Xu Key Lab of Visual Dam.g. and Reg.neration&Restoration of Chong.ing Southwest Eye HospitalSouthwest HospitalThird Military Medical University(Army Medical University)ChongqingChina

m.ller g.ia,as prom.nent g.ial cells within the retina,plays a sig.ificant role in m.intaining.retinal hom.ostasis in both healthy and diseased *** lower vertebrates like zebrafish,these cells assum. responsibility for spontaneous retinal reg.neration,wherein endog.nous m.ller g.ia underg. proliferation,transform.into m.ller g.ia-derived prog.nitor cells,and subsequently reg.nerate the entire retina with restored ***,m.ller g.ia in the m.use and hum.n retina exhibit lim.ted neural reprog.am.ing.m.ller g.ia reprog.am.ing.is thus a prom.sing.strateg. for treating.neurodeg.nerative ocular disorders.m.ller g.ia reprog.am.ing.in m.ce has been accom.lished with rem.rkable success,throug. various *** in m.lecular,g.netic,epig.netic,m.rpholog.cal,and physiolog.cal evaluations have m.de it easier to docum.nt and investig.te the m.ller g.ia prog.am.ing.process in ***,there rem.in issues that hinder im.roving.reprog.am.ing.efficiency and ***,understanding.the reprog.am.ing.m.chanism.is crucial toward exploring.factors that will im.rove m.ller g.ia reprog.am.ing.efficiency,and for developing.novel m.ller g.ia reprog.am.ing.*** review describes recent prog.ess in relatively successful m.ller g.ia reprog.am.ing.*** also provides a basis for developing.new m.ller g.ia reprog.am.ing.strateg.es in m.ce,including.epig.netic rem.deling.m.tabolic m.dulation,im.une reg.lation,chem.cal sm.ll-m.lecules reg.lation,extracellular m.trix rem.deling.and cell-cell fusion,to achieve m.ller g.ia reprog.am.ing.in m.ce.

关键词： cell fusion chem.cal sm.ll-m.lecules epig.netic extracellular m.trix im.une m.tabolic m.ce m.ller g.ia neurodeg.nerative diseases reprog.am.ing retina reg.neration

Relative accuracy of spatial predictive m.dels for lynx Lynx canadensis derived using.log.stic reg.ession-AIC,m.ltiple criteria evaluation and Bayesian approaches

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Current Zoolog. 2009年第1期55卷 28-40页

作者： Hejun kang Shelley m. ALEXANDER Center for Spatial Analysis School of Geography and Earth Sciences McMaster University Hamilton ON Canada L8S 4K1 Departm.nt of g.og.aphy University of Calgary Calgary AB Canada T2N 1N4

We com.ared probability surfaces derived using.one set of environm.ntal variables in three g.og.aphic Inform.tion System. （g.S） -based approaches： log.stic reg.ession and Akaike＇s Inform.tion Criterion （AIC）, m.ltiple Criteria Evaluation （m.E）, and Bayesian Analysis （specifically Dem.ster-Shafer theory）. We used lynx Lynx canadensis as our focal species, and developed our environm.nt relationship m.del using.track data collected in Banff National Park, Alberta, Canada, during.winters from.1997 to 2000. The accuracy of the three spatial m.dels were com.ared using.a conting.ncy table m.thod. We determ.ned the percentag. of cases in which both presence and absence points were correctly classified （overall accuracy）, the failure to predict a species where it occurred （om.ssion error） and the prediction of presence where there was absence （com.ission error）. Our overall accuracy showed the log.stic reg.ession approach was the m.st accurate （74.51%）. The m.ltiple criteria evaluation was interm.diate （39.22%）, while the Dem.ster-Shafer （D-S） theory m.del was the poorest （29.90%）. However, om.ssion and com.ission error tell us a different story： log.stic reg.ession had the lowest com.ission error, while D-S theory produced the lowest om.ssion error. Our results provide evidence that habitat m.dellers should evaluate all three error m.asures when ascribing.confidence in their m.del. We sug.est that for our study area at least, the log.stic reg.ession m.del is optim.l. However, where sam.le size is sm.ll or the species is very rare, it m.y also be useful to explore and/or use a m.re ecolog.cally cautious m.delling.approach （e.g. Dem.ster-Shafer） that would over-predict, protect m.re sites, and thereby m.nim.ze the risk of m.ssing.critical habitat in conservation plans .

关键词： Bayesian Analysis (Dem.ster-Shafer) g.S Habitat Log.stic reg.ession Lynx canadensis m.ltiple Criteria Evaluation (m.E)

A stochastic approach for integ.ating.m.rket and technical uncertainties in econom.c evaluations of petroleum.developm.nt

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Petroleum.Science 2009年第3期6卷 319-326页

作者： Chang.yup Park Joe m. kang Taewoong.Ahn BK21 Research Division for Energ. Resources Seoul National University Division of Energ. System. Eng.neering Seoul National University

The paper presents a stochastic and econom.c analysis for petroleum.developm.nt under uncertain m.rket and technical environm.nts. m.an-reversion with jum.s for price forecasting.is used to consider m.rket uncertainty, while various scenarios for the reservoir properties and cost are em.loyed to consider technical uncertainty. m.nte Carlo sim.lation is carried out to obtain the feasible rang. of net present values and internal rates of return. The influence of stochastic param.ters is exam.ned throug. correlation coefficients. The stochastic approach yields m.re reliable evaluation and effectively investig.tes the characteristics of developm.nt. The integ.ation of uncertainties and contractual term. results in an irreg.lar tendency in the future cash flow and reveals that a larg.r reserve does not g.arantee a g.eater profit. The reserve and the well rate affect the econom.c values whereas the param.ters for price prediction don＇t. The research confirm. the necessity of qualifying.uncertainties for realistic decision-m.king.at the initial stag. of developm.nt.

关键词： Uncertainty petroleum.developm.nt decision-m.king stochastic approach m.an reversion with jum.s

Particles in a circulation loop for solar energ. capture and storag.

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Particuolog. 2019年第2期17卷 149-156页

作者： Q. kang g. Flam.nt R. Dewil J. Baeyens H.L. Zhang.Y.m. Deng KU Leuven Department of Chemical Engineering Process and Environmental Technology Lab. 2860 Sint-Katelijne-Waver Belgium Processes. m.terials and Solar Energ. Laboratory PROMES-CNRS 66120 Font Romeu France European Powder & Process Technolog. 3120 Tremelo Belgium Beijing.University of Chem.cal Technolog. School of Life Science and Technology Beijing 10029 China

This study defines and assesses the selection ciiteria for suitable particulate m.terials to be used in an upflow bubbling.fluidized bed (UBFB) or dense up-flow powder circulation system.for solar energ. capture and storag.. The m.in criteria identified are based on the therm.physical and therm.m.chanical properties, attrition behavior, and the considerations of health and environm.ntal hazards of the candidate powders. Finally, a cost com.arison and tentative ranking.of the different can didate powders is presented in addition to a weig.ted scoring. Sig.ificant scoring.differences can be observed between the various m.terials. Olivine possesses the m.st favorable characteristics and appears to be the particulate m.terial of choice for solid/g.s suspension heat transfer fluids.

关键词： Concentrated solar power Particle-in-tube receiver Particle properties Selection criteria

Postnatal developm.nt of rat retina:a continuous observation and com.arison between the org.notypic retinal explant m.del and in vivo developm.nt

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Neural Reg.neration Research 2025年第3期20卷 900-912页

作者： Baoqi Hu Rui Wang.Hanyue Zhang.Xiou Wang.Sijia Zhou Bo m. Yan Luan Xin Wang.Xinlin Chen Zhichao Zhang.Qianyan kang Departm.nt of Ophthalm.log. The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’anShaanxi ProvinceChina Departm.nt of Ophthalm.log. The First Affiliated Hospital of Northwest UniversityXi’anShaanxi ProvinceChina Institute of Neurobiolog. Xi’an Jiaotong University Health Science CenterXi’anShaanxi ProvinceChina

The org.notypic retinal explant culture has been established for m.re than a decade and offers a rang. of unique advantag.s com.ared with in vivo experim.nts and cell ***,the lack of system.tic and continuous com.arison between in vivo retinal developm.nt and the org.notypic retinal explant culture m.kes this m.del controversial in postnatal retinal developm.nt ***,we aim.d to verify the feasibility of using.this m.del for postnatal retinal developm.nt studies by com.aring.it with the in vivo *** this study,we showed that postnatal retinal explants underg. norm.l developm.nt,and exhibit a consistent structure and tim.line with retinas in ***,we used SOX2 and PAX6 im.unostaining.to identify retinal prog.nitor *** then exam.ned cell proliferation and m.g.ation by im.unostaining.with Ki-67 and doublecortin,***-67-and doublecortin-positive cells decreased in both in vivo and explants during.postnatal retinog.nesis,and exhibited a hig. deg.ee of sim.larity in abundance and distribution between ***,we used Ceh-10 hom.odom.in-containing.hom.log.g.utam.te-am.onia lig.se(g.utam.ne synthetase),neuronal nuclei,and ionized calcium.binding.adapter m.lecule 1 im.unostaining.to exam.ne the em.rg.nce of bipolar cells,m.ller g.ia,m.ture neurons,and m.crog.ia,*** tim.ng.and spatial patterns of the em.rg.nce of these cell types were rem.rkably consistent between in vivo and explant *** study showed that the org.notypic retinal explant culture m.del had a hig. deg.ee of consistency with the prog.ession of in vivo early postnatal retina *** finding. confirm.the accuracy and credibility of this m.del and support its use for long.term.system.tic,and continuous observation.

关键词： bipolar cells differentiation in vivo m.crog.ia m.ller g.ia org.notypic retinal explant culture postnatal retina developm.nt proliferation retinal prog.nitor cells

Classical Electrom.g.etic Field Theory in the Presence of m.g.etic Sources

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Chinese Physics Letters 2003年第3期20卷 321-324页

作者： Li kang Chen Wen-Jun Carlos m. Naón Departm.nt of Physics Hangzhou Teacher's College Hangzhou 310036 Departm.nt of Physics Zhejiang University Hangzhou 310027 Instituto de Física La Plata Departamento de Física Facultad de Ciencias Exactas Universidad Nacional de La Plata CC 67 1900 La Plata Argentina

Using.two new well-defined four-dim.nsional potential vectors, we form.late the classical m.xwell field theory in a form.which has m.nifest Lorentz covariance and SO(2) duality sym.etry in the presence of m.g.etic sources. We set up a consistent Lag.ang.an for the theory. Then from.the action principle we obtain both m.xwell's equation and the equation of m.tion of a dyon m.ving.in the electrom.g.etic field.

关键词： m.xwell equations

Exact solutions for unsteady unidirectional flows of a g.neralized second-order fluid throug. a rectang.lar conduit

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Acta m.chanica Sinica 2009年第2期25卷 181-186页

作者： J. kang m. Xu School of m.them.tics, Institute of Applied m.them.tics,Shandong.University, 250100 Jinan, China m. Xu School of m.them.tics Institute of Applied Mathematics Shandong University 250100 Jinan China

The exact solutions are obtained for unsteady unidirectional flows of a g.neralized second-order fluid throug. a rectang.lar conduit. The fractional calculus in the constitutive relationship of a non-Newtonian fluid is introduced. We construct the solutions by m.ans of Fourier transform.and the discrete Laplace transform.of the sequential derivatives and the double finite Fourier transform. The solutions for Newtonian fluid between two infinite parallel plates appear as lim.ting.cases of our solutions.

关键词： g.neralized second-order fluid - Rectang.larconduit Fractional calculus Exact solutions

Therm.l Characteristics in the Cutting.of Inconel 718 Superalloy Using.CW Nd:YAg.Laser

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Journal of m.terials Science & Technolog. 2010年第4期26卷 362-366页

作者： D.g. Ahn K.W. Byun m.C. kang Departm.nt of m.chanical Eng.neering Chosun University 375 Seosuk-dong Dong-gu Gwang-ju 501-759 Korea Hybrid m.terials Solution National Core Research (NCRC) Pusan National University San 30 Changjeon-dong Keumjeong-gu Busan 609-735 Korea

The objective of the this study is to investig.te the effects of cutting.param.ters on therm.l characteristics, including.practical cutting.reg.ons, the form.tion of the kerfwidth and the heat transfer phenom.non, in the cutting.of Inconel 718 super-alloy sheets using.a CW Nd：YAg.laser. From.the results of the experim.nts, the influence of process param.ters on both the practical cutting.reg.on and the kerfwidth has been exam.ned. In addition, it has been shown that the kerfwidth of the specim.n lies in the rang. of 0.53-0.61 m.. In order to exam.ne characteristics of the heat transfer during.the laser cutting.process, a three-dim.nsional quasi-steady heat transfer analysis has been perform.d using.the com.ercial code SYSWELD V9.0. From.the results of the analysis, the influence of cutting.param.ters on the tem.erature distribution in the vicinity of the cut section has been quantitatively evaluated. Based on these results, optim.l cutting.conditions have been estim.ted.

关键词： CW Nd:YAg.laser Inconel 718 Kerfwidth Quasi-steady heat transfer analysis

Effect of Injection Velocity on Structure Part Characteristic in AZ50 Die Casting.Process with Hig. Vacuum.System

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Journal of m.terials Science & Technolog. 2008年第1期24卷 75-79页

作者： S.m.Lee P.K.Seo C.g.kang Korea School of m.chanical Eng.neering.Pusan National University Busan 609-735

When diecasting.larg. and thin m.0}alloy parts,m.terial defects occur,which include porosity,nonuniform.m.chanical properties,irreg.lar surfaces,and incom.lete *** resolve these problem.,it is necessary to have uniform.injection velocities and tem.eratures as well as control the *** study investig.ted the feasibility of producing.larg. and thin com.onents using.a die caster by attaching.a hig. vacuum.*** particular,the effects of injection velocity on surface quality and the m.chanical properties of the products were ***,an injection velocity schem. and a die structure capable of casting.in a vacuum.were *** a result,it was found that the critical low injection velocity was 0.2 m.s to produce larg. thin m.0}alloy structures having.g.od m.chanical properties.

关键词： m.0}die casting Injection velocity Vacuum.system