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Biomedical and Environmental Sciences 2013年第8期26卷 638-646页

作者： WANG Xi CHEN Ren Jie CHEN Bing Heng kan hai dong School of Public Health Key Laboratory of Public Health Safety of Ministry of Education Fudan University Institute of Global Environment Change Fudan University Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention Fudan University Shanghai Key Laboratory of Meteorology and Health Shanghai Meteorological Bureau

Objective To estimate the frequency of daily average PM10 concentrations exceeding the air quality standard （AQS） and the reduction of particulate matter emission to meet the AQS from the statistical properties （probability density functions） of air pollutant concentration. Methods The daily PM10 average concentration in Beijing, Shanghai, Guangzhou, Wuhan, and Xi＇an was measured from 1 January 2004 to 31 December 2008. The PM10 concentration distribution was simulated by using the Iognormal, Weibull and Gamma distributions and the best statistical distribution of PM10 concentration in the 5 cities was detected using to the maximum likelihood method. Results The daily PM10 average concentration in the 5 cities was fitted using the Iognormal distribution. The exceeding duration was predicted, and the estimated PMlo emission source reductions in the 5 cities need to be 56.58%, 93.40%, 80.17%, 82.40%, and 79.80%, respectively to meet the AO, S. Conclusion Air pollutant concentration can be predicted by using the PM10 concentration distribution, which can be further applied in air quality management and related policy making.

关键词： Statistical distribution PM10 concentration Lognormal

Impact of Temperature on Mortality in Three Major Chinese Cities

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Biomedical and Environmental Sciences 2014年第7期27卷 485-494页

作者： ZHANG Jing LI Tian Tian TAN Jian Guo HUANG Cun Rui kan hai dong School of Public Health Key Laboratory of Public Health Safety of Ministry of EducationFudan University Institute of Environmental Health and Related Product Safety China Center for Disease Control and Prevention Shanghai Key Laboratory of Meteorology and Health Shanghai Meteorological InstituteSMB School of Public Health and Institute of Health and Biomedical Innovation Queensland University of Technology Research Institute for the Changing Global Environment and Fudan Tyndall Centre Fudan University Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention Fudan University

Objective To study the relation between temperature and mortality by estimating the temperature-related mortality in Beijing, Shanghai, and Guangzhou. Methods Data of daily mortality, weather and air pollution in the three cities were collected. A distributed lag nonlinear model was established and used in analyzing the effects of temperature on mortality. Current and future net temperature-related mortality was estimated. Results The association between temperature and mortality was J-shaped, with an increased death risk of both hot and cold temperature in these cities. The effects of cold temperature on health lasted longer than those of hot temperature. The projected temperature-related mortality increased with the decreased cold-related mortality. The mortality was higher in Guangzhou than in Beijing and Shanghai. Conclusion The impact of temperature on health varies in the 3 cities of China, which may have implications for climate policy making in China.

关键词： Climate change Temperature Mortality Time-series

Association between Ambient Air Pollution and Outpatient Visits for Acute Bronchitis in a Chinese City

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Biomedical and Environmental Sciences 2014年第11期27卷 833-840页

作者： GUO Li Juan ZHAO Ang CHEN Ren Jie kan hai dong KUANG Xing Ya DepartmentofOccupationalMedicine YangpuHospitalTongjiUniversity Department of Occupational Medicine Shanghai Yangpu District Central Hospital Pudong New Area Centers for Disease Control and Prevention School of Public Health Key Laboratory of Public Health Safety of the Ministry of EducationFudan University Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention (LAP3) Fudan University Research Institute for the Changing Global Environment and Fudan Tyndall Centre Fudan University

Objective To investigate the short-term association between outdoor air pollution and outpatient visits for acute bronchitis,which is a rare subject of research in the mainland of China.Methods A time-series analysis was conducted to examine the association of outdoor air pollutants with hospital outpatient visits in Shanghai by using two-year daily data（2010-2011）.Results Outdoor air pollution was found to be associated with an increased risk of outpatient visits for acute bronchitis in Shanghai.The effect estimates of air pollutants varied with the lag structures of the concentrations of the pollutants.For lag06,a 10 μg/m3 increase in the concentrations of PM10,SO2,and NO2 corresponded to 0.94%（95% CI：0.83%,1.05%）,11.12%（95% CI：10.76%,11.48%）,and 4.84%（95% CI：4.49%,5.18%） increases in hospital visits for acute bronchitis,respectively.These associations appeared to be stronger in females（P〈0.05）.Between-age differences were significant for SO2（P〈0.05）,and between-season differences were also significant for SO2（P〈0.05）.Conclusion Our analyses have provided the first evidence that the current air pollution level in China has an effect on acute bronchitis and that the rationale for further limiting air pollution levels in Shanghai should be strengthened.

关键词： Air pollution Outpatient visits Acute bronchitis Time-series

Ambient Temperature and Outpatient Visits for Acute Exacerbation of Chronic Bronchitis in Shanghai: A Time Series Analysis

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Biomedical and Environmental Sciences 2015年第1期28卷 76-79页

作者： HUANG Fang ZHAO Ang CHEN Ren Jie kan hai dong KUANG Xing Ya Department of Occupational Medicine Yangpu Hospital Tongji University School of Medicine Department of Occupational Medicine Yangpu District Central Hospital Institute of Occupational and Environmental Medicine Medical School Tongji University School of Medicine School of Public Health Key Lab of Public Health Safety of the Ministry of Education Fudan University Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention (LAP3) Fudan University Research Institute for the Changing Global Environment and Fudan Tyndall Centre Fudan University

The association between ambient temperature and acute exacerbation of chronic bronchitis （AECB） was still unknown. Therefore, we performed an epidemiological study in a large hospital of Shanghai to explore the relationship about temperature and outpatient visit for AECB. We adopted a quasi-Poisson generalized additive models and distributed lag nonlinear models to estimate the accumulative effects of temperature on AECB across multiple days. We found significant non-linear effects of cold temperature on hospital visits for AECB, and the potential effect of cold temperature might last more than 2 weeks. The relative risks of extreme cold （first percentiles of temperature throughout the study period） and cold （10th percentile of temperature） temperature over lags 0-14 d were 2.98 [95% confidence intervals （CI）： 1.77, 5.04] and 1.63 （95% Ch 1.21, 2.19）, compared with the 25th percentile of temperature. However, we found no positive association between hospital visits and hot weather. This study showed that exposure to both extreme cold and cold temperatures were associated with increased outpatient visits for AECB in a large hospital of Shanghai.

关键词： AECB Ambient Temperature and Outpatient Visits for Acute Exacerbation of Chronic Bronchitis in Shanghai

Association Between Diurnal Temperature Range and Respiratory Tract Infections

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Biomedical and Environmental Sciences 2013年第3期26卷 222-225页

作者： GE Wen Zhen XU Feng ZHAO Zhuo Hui ZHAO Jin Zhuo kan hai dong School of Public Health Key Lab of Public Health Safety of the Ministry of EducationFudan University G_RI° CE(Research Institute for the Changing Global Environment) and Fudan Tyndall Centre Fudan University Department of Dermatology Huashan HospitalFudan University G_RI° CE (Research Institute for the Changing Global Environment) and Fudan Tyndall Centre Fudan University Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention (LAP~3) Department of Environmental Science & EngineeringFudan University

Objective This study aimed to assess the association between emergency-room visits for respiratory tract infection （RTI） with diurnal temperature range （DTR）, a weather parameter closely associated with urbanization and global climate change. Methods We conducted a semiparametric time-series analysis to estimate the percentage increase in emergency-room visits for RTI associated with changes in DTR after adjustment for daily weather conditions （temperature and relative humidity） and outdoor air pollution. Results DTR was significantly associated with daily emergency-room visits for RTI. An increase of 1 ~C in the current-day （LO） and in the 2-day moving average （L01） DTR corresponded to a 0.94% [95% confidence interval （CI）, 0.34%-1.55%] and 2.08% （95% CI, 1.24%-2.93%） increase in emergency-room visits for RTI, respectively. Conclusion DTR was associated with increased risk of RTI. More studies are needed to understand the impact of DTR on respiratory health.

关键词： Acute respiratory tract infection Diurnal temperature range Time-series

Short-term Effects of Air Pollution on Mortality in a Heavily Polluted Chinese City

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Biomedical and Environmental Sciences 2013年第8期26卷 671-674页

作者： WANG Zong Shuang CHEN Ren Jie WU Ji Rao kan hai dong WU Gang WU Xue Fang State Key Laboratory of Urban and Regional Ecology Research Center for Eco-Environmental Sciences Chinese Academy of Sciences Chinese Research Academy of Environmental Sciences School of Public Health Key Lab of Public Health Safety of the Ministry of Education Fudan University Research Institute for Changing Global Environment and Fudan Tyndall Centre Fudan University School of Public Health Xinjiang Medical University Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention(LAP3) Fudan University

Since the London fog in 1952, numerous epidemioLogical studies have revealed that both short-term and long-term exposure to air pollutants is associated with the development of diseases[1]. Up to date, the assessment of air quality on health and air quality standard establishment in developing countries were mainly relied on extrapolation based on the results from long-term cohort studies conducted in Europe and North America.

关键词： Short-term Effects of Air Pollution on Mortality in a Heavily Polluted Chinese City

A Genetic Susceptibility Study of Lung Cancer Risk Potentially Associated with Polycyclic Aromatic Hydrocarbon Inhalation Exposure

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Biomedical and Environmental Sciences 2017年第10期30卷 772-776页

作者： LIN Nan MU Xin Lin WANG Gui Lian REN Yu Ang TANG De Liang WANG Bin LI Zhi Wen SU Shu kan hai dong TAO Shu Laboratory of Earth Surface Processes College of Urban and Environmental SciencesPeking UniversityBeijing100871China Department of Respiratory and Critical Care Medicine Peking University People's HospitalBeijing 100044China Intensive Care Unit Beijing First Hospital of Integrated Chinese and Western MedicineBeijing 100026China Department of Environmental Health Sciences Mailman School of Public HealthColumbia UniversityNew YorkNew York 10032United States of America Institute of Reproductive and Child Health/Ministry of Health Key Laboratory of Reproductive Health School of Public HealthPeking UniversityBeijing 100191China School of Public Health Key Lab of Public Health Safety of the Ministry of Education and Key Lab of Health Technology Assessment of the Ministry of HealthFudan UniversityShanghai 200032China

For lifetime non-smokers, lung cancer risk is mainly associated with inhalation exposure to air pollution. For the Chinese population, indoor air pollution due to solid fuel combustion has been the primary source of inhalation exposure for decades. Polycyclic aromatic hydrocarbons （PAHs） are the by-products of incomplete combustion.

关键词： GSS A Genetic Susceptibility Study of Lung Cancer Risk Potentially Associated with Polycyclic Aromatic Hydrocarbon Inhalation Exposure

Impact of Atmospheric Transmittance and NLTE Correction on Simulation of High Spectral Infrared Atmospheric Sounder onboard FY-3E

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Journal of Meteorological Research 2024年第2期38卷 225-234页

作者： Chenggege FANG Peiming dong Yang HAN Wanlin kan Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters Key Laboratory for Aerosol-Cloud-Precipitation of China Meteorological AdministrationNanjing University of Information Science&TechnologyNanjing 210044 donghai Laboratory Zhoushan 316021 State Key Laboratory of Severe Weather Chinese Academy of Meteorological SciencesChina Meteorological AdministrationBeijing 100081 CMA Earth System Modeling and Prediction Centre China Meteorological Administration(CMA)Beijing 100081 Key Laboratory of Transportation Meteorology of China Meteorological Administration Nanjing Joint Institute for Atmospheric SciencesNanjing 210041

With the launch of the first civilian early-morning orbit satellite Fengyun-3E(FY-3E),higher demands are placed on the accuracy of radiative transfer simulations for hyperspectral infrared data.Therefore,several key issues are investigated in the paper.First,the accuracy of the fast atmospheric transmittance model implemented in the Advanced Research and Modeling System(ARMS)has been evaluated with both the line-by-line radiative transfer model(LBLRTM)and the actual satellite observations.The results indicate that the biases are generally less than 0.25 K when compared to the LBLRTM,while below 1.0 K for the majority of the channels when compared to the observations.However,during both comparisons,significant biases are observed in certain channels.The accuracy of Hyperspectral Infrared Atmospheric Sounder-II(HIRAS-II)onboard FY-3E is comparable to,and even superior to that of the Cross-track Infrared Sounder(CrIS)onboard NOAA-20.Furthermore,apodization is a crucial step in the processing of hyperspectral data in that the apodization function is utilized as the instrument channel spectral response function to produce the satellite channel-averaged transmittance.To further explore the difference between the apodized and unapodized simulations,Sinc function is adopted in the fast transmittance model.It is found that the use of Sinc function can make the simulations fit the original satellite observations better.When simulating with apodized observations,the use of Sinc function exhibits larger deviations compared to the Hamming function.Moreover,a correction module is applied to minimize the impact of Non-Local Thermodynamic Equilibrium(NLTE)in the shortwave infrared band.It is verified that the implementation of the NLTE correction model leads to a significant reduction in the bias between the simulation and observation for this band.

关键词： high spectral infrared sounding atmospheric transmittance apodization Non-Local Thermodynamic Equilibrium Fengyun-3E(FY-3E)

Impact of Long-term Exposure to Air Particulate Matter on Life Expectancy and Survival Rate of Shanghai Residents

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Biomedical and Environmental Sciences 2002年第3期15卷 209-214页

作者： kan hai-dong1 AND CHEN BING-HENG Department of Environmental Health, School of Public Health, Fudan University, Shanghai 200032, China Department of Environmental Health School of Public Health Fudan University 上海 200032

Objective To evaluate the impact of long-term air particulate matter exposure on the life expectancy and survival rate of Shanghai residents. Methods Epidemiology - based exposure-response function was used for the calculation of attributable deaths to air particulate matter in Shanghai, and the effect of long-term exposure to particulate matter on life expectancy and survival rate was estimated using the life table of Shanghai residents in 1999. Results It was shown that in 1999, the long-term air particulate matter exposure caused 1.34-1.69 years reduction of life expectancy and a decrease of survival rate for each age group of Shanghai residents. Conclusion The effect of long-term exposure to air particulate matter on life expectancy is substantial in Shanghai.

关键词： Particulate matter Life expectancy Survival rate Shanghai

Balancing act:The dilemma of rapid hyperglycemia correction in diabetes management

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World Journal of Diabetes 2024年第2期15卷 129-132页

作者： Ke-Xin Zhang Cheng-Xia kan Xiao-dong Sun Department of Endocrinology and Metabolism Affiliated Hospital of Weifang Medical UniversityWeifang 261031Shandong ProvinceChina

The global diabetes surge poses a critical public health challenge,emphasizing the need for effective glycemic control.However,rapid correction of chronic hyperglycemia can unexpectedly trigger microvascular complications,necessitating a reevaluation of the speed and intensity of glycemic correction.Theories suggest swift blood sugar reductions may cause inflammation,oxidative stress,and neurovascular changes,resulting in complications.Healthcare providers should cautiously approach aggressive glycemic control,especially in long-standing,poorly controlled diabetes.Preventing and managing these complications requires a personalized,comprehensive approach with education,monitoring,and interdisciplinary care.Diabetes management must balance short and longterm goals,prioritizing overall well-being.This editorial underscores the need for a personalized,nuanced approach,focusing on equilibrium between glycemic control and avoiding overcorrection.

关键词： Diabetes Hyperglycemia correction Management Microvascular complications Glucose control