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Invasive Fungal Sinusitis in Immunocompromised Patients: A Multicenter, University Hospital Experience in Shiraz

Advances in Infectious Diseases 2013年第4期3卷 263-268页

作者： Mohsen Moghadami Hossein Ruzbahani Parisa badiee Abolhassan Faramarzi Payam Peymani kamran bagheri lankarani Alborzi Clinical Microbiology Research Center Shiraz University of Medical Sciences Shiraz Iran Department of Internal Medicine Shiraz Uni- versity of Medical Sciences Shiraz Iran Department of Otolaryngology Shiraz University of Medical Sciences Shiraz Iran Health Policy Research Center Shiraz University of Medical Sciences Shiraz Iran

Objective: It is to determine the causes of invasive fungal sinusitis in patients of Shiraz University hospitals, Iran. Methods: This cross-sectional study was conducted during 18 months (from 21 March 2009 till 22 September 2010) in three Shiraz University Hospitals. Thirty-six patients with sings of invasive fungal sinusitis were enrolled, and tissue samples were investigated for histopathology, culture and antifungal susceptibility test. The laboratory results with host factor and sinus computed tomography scan were evaluated for classification of patients as proven, probable and possible invasive fungal sinusitis. Results: Thirty-five patients have involved with at least one risk factor (immune compromised disease, diabetes mellitus, or use of immune suppressed drugs). Radiological findings of parasinus invasion or necrosis were present in 20 patients. by histopathology, 21 patients were considered as proven, from these, 17 samples had positive growth. The culture aetiology agents were 4 Candida, 8 Aspergillus, and 5 Mucor. All positive culture samples were matched with histopathology findings. Significant associations were considered for radiologic finding and histopathology and culture (p 0.05). From 8 patients with mucormycosis histopathology, 6 suffered from diabetes mellitus. None of the antifungal agents were effective on these three types of infections. Conclusion: DM is the most common predisposing factor for IFS followed by ALL and AML. The most common aetiology of IFS was found to be Aspergillus fumigant followed by Mucormycosis and Candida. None of antifungal agents could successfully cover all the species.

关键词： Fungal Sinusitis Mucor Mycosis Aspergillus Invasive Fungal

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青藏高原及其周边白垩纪综合地层、生物群与古地理演化

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中国科学：地球科学 2024年第4期54卷 1244-1307页

作者：席党鹏李国彪姜仕军饶馨江湉王天洋覃祚焕王亚苏贾建忠 Muhammad kamran 史忠叶吴於洋王盘喜孙立新曾庆高万晓樵中国地质大学(北京)生物地质与环境地质国家重点实验室北京100083 河海大学海洋学院南京213200 中国科学院南京地质古生物研究所古生物学与油气地层应用重点实验室南京210008 中国科学院青藏高原研究所青藏高原地球系统与资源环境重点实验室北京100101 中国海洋石油国际有限公司北京100028 上海科技馆上海200120 西藏自治区地质矿产勘查开发局拉萨850000 中国地质调查局天津地质调查中心天津300170

白垩纪是新特提斯洋演化和青藏高原不同板块汇聚的关键时期,详细的地层框架和古地理格局是开展新特提斯洋演化和青藏高原形成研究的基础.本文对青藏高原及周边白垩纪地层、古生物、古地理和重大地质事件开展了系统分析,以建立综合地层框... 详细信息

白垩纪是新特提斯洋演化和青藏高原不同板块汇聚的关键时期,详细的地层框架和古地理格局是开展新特提斯洋演化和青藏高原形成研究的基础.本文对青藏高原及周边白垩纪地层、古生物、古地理和重大地质事件开展了系统分析,以建立综合地层框架,恢复不同时期的古地理格局,探讨重大地质事件的响应和耦合关系.青藏高原及其周边白垩纪地层以海相为主,发育少量海陆交互相和陆相沉积.印度-雅鲁藏布江缝合带发育以蛇绿岩套和含放射虫硅质岩为主的深海沉积,其南侧的特提斯喜马拉雅、印度河盆地等发育浅海至半深海-深海沉积,北侧的日喀则-拉达克弧前盆地发育浅海-半深海相沉积,拉萨地块、喀喇昆仑-塔里木盆地西部和西缅地块等发育浅海、海陆过渡相和陆相沉积,羌塘盆地等其余地区则以陆相沉积为主.青藏高原及其邻区白垩纪地层分布广泛,类型多样,富含有孔虫、钙质超微、放射虫、菊石、双壳类和孢粉等多门类化石;基于岩石地层、生物地层、同位素年代地层和稳定同位素地层等多重地层划分与对比,建立了不同分区地层的划分与对比关系,提出了新的东特提斯区白垩纪综合地层框架.划分了白垩纪新特提斯洋东段及周边不同地理分区的生物群落,阐明了其时空分布特征,恢复了不同时期的生物古地理面貌.青藏高原及周边白垩纪古地理演化可划分为3个阶段:(1)印度板块与澳大利亚-南极洲大陆逐步裂解、拉萨-羌塘地块早期碰撞阶段(145~125Ma);(2)印度板块向北漂移和拉萨-羌塘地块晚期碰撞阶段(125~100Ma);(3)印度板块快速向北漂移、塔里木-喀喇昆仑海湾形成和冈底斯山早期隆升阶段(100~66Ma).白垩纪中期(100Ma左右),印度-特提斯喜马拉雅生物区系经历了冈瓦纳大陆冷水型向特提斯暖水型的转变,海洋生物的多样性达到全盛;白垩纪末期,海洋生物急剧衰退.伴随着印度板块向北漂移和新特提斯洋的演化,新特提斯洋发生了大火成岩省、大洋缺氧、白垩纪大洋红层,以及生物辐射与灭绝等一系重大地质事件.

关键词：青藏高原特提斯白垩纪地层生物群古地理

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Educational level and age as contributing factors to road traffic accidents

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Chinese Journal of Traumatology 2013年第5期16卷 281-285页

作者： Ashkan Sami Ghasem Moafian Arman Najafi Mohammad Reza Aghabeig Navid Yamin Seyed Taghi Heydari kamran b.lankarani Department of Computer Science and Engineering School of Electrical Engineering and Computer ShirazUniversity Shiraz Iran Health Policy Research Center Shiraz University ofMedical Sciences Shiraz Iran Department of biostatistics Jahrom University of Medi-cal Sciences Jahrom Iran

Objective： This research analyzes data on road traffic accidents （RTA） in Fars province, whose roads are among the highly dangerous ones in Iran. It inves- tigates educational level and age involved in RTA in order to discover patterns that can prevent or decrease accidents. Methods： This research made use of data visualization techniques to find hidden patterns. The data included mor- tality rate related to RTA in Fars province and were obtained from Fars Forensic Medicine Registry covering a period of 1 year from March 21, 2010 to March 21, 2011. All data were analyzed using SPSS 11.5. The results were reported as de- scriptive indices such as frequency （percentage）. The Chi- square test was applied to the data concerning educational level and age. P value less than 0.05 was considered significant. Results： In the mentioned period, 1 831 people were killed, out of whom un/lowly educated people （69.6%） ac- counted for the highest mortality rate. The significant rela- tionship between educational level and mortality rate was found （X2=275.98, P〈0.0001）. Also three was a significant association between age and mortality rate （X2=371.20, P〈0.0001）. Young people （age between 20 and 29 years） contribute to higher RTA mortality rate compared with other age groups. Conclusion： The educational level and age are signifi- cantly correlated to mortality rate. The youth and un/lowly educated people suffer more fatal RTA.

关键词： Accidents, traffic Mortality Education Data mining Iran

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Hepatitis b Vaccination in Medical and Dental Students: A Cross-Sectional Study

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Open Journal of Internal Medicine（内科学期刊） 2024年第1期 122页

作者： Md.Usama Nasr Md.kamran Saleem Abdullah Saeed

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An epidemiologic survey of road traffic accidents in Iran： analysis of driver-related factors

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Chinese Journal of Traumatology 2013年第3期16卷 140-144页

作者： Ghasem Moafian Mohammad Reza Aghabeigi Seyed Taghi Heydari Amin Hoseinzadeh kamran bagheri lankarani Yaser Sarikhani Health Policy Research Center School of MedicineShiraz University of Medical Sciences Shiraz Iran

ObjectiveRoad 交通事故(RTA ) 和它的相关损害在伊朗贡献疾病的负担的重要部分。这份报纸在 countryMethodsThis 探索在司机相关的因素和 RTA 之间的协会代表性的学习从 2010 年 3 月 20 日关于 RTA 在伊朗和所有数据被进行到 2010 年... 详细信息

ObjectiveRoad 交通事故(RTA ) 和它的相关损害在伊朗贡献疾病的负担的重要部分。这份报纸在 countryMethodsThis 探索在司机相关的因素和 RTA 之间的协会代表性的学习从 2010 年 3 月 20 日关于 RTA 在伊朗和所有数据被进行到 2010 年 6 月 10 日从交通警察部门被获得。我们包括了 538 588 RTA 记录，它被分类为主要 confounders 控制：事故类型，事故的最后的原因，事故的时间和司机相关的因素。司机相关的因素包括了性，教育水平，许可证类型，损害的类型，在事故之间的持续时间并且得到驾驶执照和 538 588 位司机的 driver’s 错误 *** 总数(91.83% 男性，几乎 13:1 的性比率) 涉及 RTA。在他们之中 423 (78.71%) 932 是未受损伤的；224 (41.74%) 818 有证书度。等级 2 驾驶执照代表了所有驾驶执照的最高的比例(290 811， 54.00%) 。事故的最大的数字发生在 12:00-13:59 (75 024， 13.93%) 。涉及 RTA 的司机的比例在在 10 以后得到一个驾驶执照到 3.13% 的第一年里从 15.90% 减少了； years’驾驶经验。规定的疏忽是交通碰撞的最普通的原因(345 589， 64.17%) 。到前面的优先级和疏忽的违反是死亡的最经常的最后的原因(138 175， 25.66% 和 129 352， 24.02% ，分别地) 。我们发现了在事故和性的类型之间的重要协会，教育，许可证类型，事故的时间，事故的最后的原因，在事故之间的 driver’s 错误以及持续时间并且得到驾驶执照(所有 P ；< ； 0.001 ) .ConclusionOur 结果将改进交通法律实施措施，它将改变司机的不恰当的行为并且保护最不富有经验的道路用户。

关键词： Accidents, traffic Automobile driving Wounds and injuries Mortality Iran

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Promoter polymorphism of transforming growth factor-β1 gene and ulcerative colitis

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World Journal of Gastroenterology 2008年第2期14卷 243-247页

作者： b Tamizifar Kb.lankarani S Naeimi M Rismankar Zadeh A Taghavi A Ghaderi Department of Internal Medicine Namazee Hospital Shiraz Iran Shiraz Institute of Cancer Research School of Medicine Shiraz University of Medical SciencesShiraz Iran

AIM: To elucidate the possible difference in two promoter polymorphisms of the transforming growth factor-β1 (TGF-β1) gene (-800G > A, -509C > T) between ulcerative colitis (UC) patients and normal ***: A total of 155 patients with established ulcerative colitis and 139 normal subjects were selected as controls. Two single nucleotide polymorphisms within the promoter region of TGF-β1 gene (-509C > T and -800G > A) were genotyped using PCR-RFLP. RESULTS: There was a statistically significant difference in genotype and allele frequency distributions between UC patients and controls for the -800G > A polymorphism of the TGF-β1 gene (P between the patients and healthy controls (P between the patients and control ***: The results of our study indicate that there is a significant difference in both allele and genotype frequency at position -800G > A of TGF-β1 gene promoter between Iranian patients with UC and normal subjects.

关键词： Transforming growth factor-β1 Ulcerativecolitis Promoter Polymorphism Iran

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A hybrid framework to analyze crisis management system maturity in sociotechnical systems

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Journal of Safety Science and Resilience 2022年第4期3卷 302-320页

作者： kamran Gholamizadeh Esmaeil Zarei Saman Poursiahbidi Omid Kalatpour Center of Excellence for Occupational health and research Center of Health SciencesHamadan University of Medical SciencesHamadan ***Iran Centre for Risk Integrityand Safety Engineering(C-RISE)Faculty of Engineering and Applied ScienceMemorial University of NewfoundlandNL A1B 3X5Canada HSE Management Department Occupational Health and Safety Research CenterHamadan University of Medical SciencesHamadan ***Iran

In recent decades,numerous catastrophic accidents have occurred worldwide,ranging from natural events(such as tsunamis,flooding,and earthquakes)to industrial events(such as mining and chemical process disasters).They endanger humans,the environment,organizations,and societies,as well as national ***,there have been few attempts to propose a model for assessing the required capabilities and potential challenges in crisis management system maturity(CMSM).Accordingly,this study proposes a framework for measuring CMSM levels in complex *** this end,a CMSM taxonomy was developed,including aspects,dimensions,and factors influencing the *** inference sets and fuzzy analytical hierarchy processes are then used for knowledge acquisition,quantification of the CMSM,and dealing with epistemic *** actual complex petrochemical plant is investigated to evaluate its *** findings revealed the most significant con-tributing factors:the CMSM’s current capability and challenges level(score),as well as the capacity to overcome the potential crisis response ***,the proposed model can be used as a practical approach for various chemical-processing plants.

关键词： Crisis management system maturity Crisis capabilities Crisis challenges Chemical process industries Fuzzy sets theory

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Determination of multiaxial stress rupture criteria for creeping materials:A critical analysis of different approaches

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Journal of Materials Science & Technology 2023年第6期137卷 14-25页

作者： Kun Zhang Jian-Ping Tan Wei Sun kamran Nikbin Shan-Tung Tu Key Laboratory of Pressure Systems and Safety(Ministry of Education) School of Mechanical and Power EngineeringEast China University of Science and TechnologyShanghai200237China Department of Mechanical Materials and Manufacturing EngineeringUniversity of NottinghamNottinghamNG72RDUK Department of Mechanical Engineering Imperial College LondonLondonSW72AZUK

Materials in engineering applications are rarely *** reality,failures under multiaxial loading has been widely observed in engineering *** life prediction of a component under multiaxial stresses has long been a challenging issue,particularly for high temperature *** distinguish the mode of failure ranging from a maximum principal stress intergranular damage to von Mises effective stress rupture mode a multiaxial stress rupture criterion(MSRC)was originally proposed by Sdobyrev and then Hayhurst and Leckie(SHL MSRC).A multiaxial-factor,α,was developed as a result which was intended to be a material constant and differentiates the bias of the MSRC between maxi-mum principal stress and effective *** success of the SHL MSRC relies on accurately calibrating the value ofαto quantify the multiaxial response of the material/geometry *** find a more suitable approach for determining MSRC,the applicability of different methods are *** that the resulting analysis of the various approaches can be affected by the creep failure mechanism,princi-ples in the determination of MSRC with and without using continuum damage mechanics approaches are *** viability of uniaxial material parameters in correlating withαthrough the analysis of available data in literature is also *** is found that the increase of the uniaxial creep dam-age tolerance parameterλis accompanied bythe decreaseof theα-value,whichimplies thatthe creep ductility plays an important role in affecting the multiaxial rupture behavior of materials.

关键词： Multiaxial stress rupture criterion Creep failure mechanism Uniaxial parameter Creep damage tolerance parameter Continuum damage mechanics

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Identification of novel catalytic features of endo-β-1,4-glucanase produced by mulberry longicorn beetle Apriona germari

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Journal of Zhejiang University-Science b(biomedicine & biotechnology) 2007年第10期8卷 765-770页

作者： SAMI Amtul Jamil HAIDER Mohammed kamran Institute of biochemistry and biotechnology University of the Punjab Lahore 54594 Pakistan

Mulberry longicorn beetle, Apriona germari, has been reported to produce two endo-β-1,4-glucanases or AgEGases (accession Nos. Q6SS52 and Q5XQD1). AgEGase sequence contains catalytic motif (amino acid residues 37~48), which is the characteristic of family Glycohydrolase 45 and is identified as the substrate binding site. The application of bioinformatics ap-proaches includes sequence analysis, structural modeling and inhibitor docking to relate the structure and function of AgEGases. We have dissected the sequence and structure of AgEGase catalytic motif and compared it with crystal structure of Humicola insolens endoglucanases V. The results show an involvement of sulfur containing amino acid residues in the active site of the enzyme. Cys residues and position of disulfide bonds are highly conserved between the two structures of endoglucanases of A. germari. Surface calculation of AgEGase structure in the absence of Cys residues reveals greater accessibility of the catalytic site to the substrate involving Asp42, a highly conserved residue. For the inhibition study, tannin-based structure was docked into the catalytic site of AgEGase using ArgusLab 4.0 and it resulted in a stable complex formation. It is suggested that the inhibition could occur through formation of a stable transition state analog-enzyme complex with the tannin-based inhibitor, as observed with other insect cellulases in our laboratory.

关键词： Cellulases AgEGase Apriona germari Inhibition Anthocyanidins

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Digital mapping of soil phosphorous sorption parameters (PSPs) using environmental variables and machine learning algorithms

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International Journal of Digital Earth 2023年第1期16卷 1752-1769页

作者： Sanaz Saidi Shamsollah Ayoubi Mehran Shirvani kamran Azizi Shuai Zhao Department of Soil Science College of AgricultureIsfahan University of TechnologyIsfahanIran Department Xinjiang Institute of Ecology and Geography Chinese Academy of Sciences818 South Beijing RoadUrumqiPeople’s Republic of China

In this study some soil phosphorous sorption parameters(PSPs)by using different machine learning models(Cubist(Cu),random forest(RF),support vector machines(SVM)and Gaussian process regression(GPR))were *** results showed that using the topographic attributes as the sole auxiliary variables was not adequate for predicting the ***,remote sensing data and its combination with soil properties were reliably used to predict PSPs(R^(2)=0.41 for MbC by RF model,R^(2)=0.49 for PbC by Cu model,R^(2)=0.37 for SPR by Cu model,and R^(2)=0.38 for SbC by RF model).The lowest RMSE values were obtained for MbC by RF model,PbC by SVM model,SPR by Cubist model and SbC by RF *** results also showed that remote sensing data as the easily available datasets could reliably predict PSPs in the given study *** outcomes of variable importance analysis revealed that among the soil properties cation exchange capacity(CEC)and clay content,and among the remote sensing indices b5/b7,Midindex,Coloration index,Saturation index,and OSAVI were the most imperative factors for predicting *** studies are recommended to use other proximally sensed data to improve PSPs prediction to precise decision-making throughout the landscape.

关键词： Soil fertility random forest adsorption isotherms remote sensing variable importance analysis

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