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Exploring charge and spin fluctuations in infinite-layer cuprate SrCuO_(2)from a phonon perspective

Science China(Physics,Mechanics & Astronomy) 2024年第8期67卷 159-167页

作者： Xin Du Pei-Han Sun Ben-Chao Gong Jian-Feng Zhang Zhong-yi Lu kai Liu Department of Physics and Beijing Key Laboratory of Opto-electronic Functional Materials&Micro-nano Devices Renmin University of ChinaBeijing 100872China Department of Physics School of ScienceJiangsu University of Science and TechnologyZhenjiang 212100China Institute of Physics Chinese Academy of SciencesBeijing 100190China Key Laboratory of Quantum State Construction and Manipulation(Ministry of Education) Renmin University of ChinaBeijing 100872China

The infinite-layer cuprate ACu O_(2)(A=Ca,Sr,Ba)possesses the simplest crystal structure among numerous cuprate superconductors and can serve as a prototypical system to explore the unconventional *** on the first-principles electronic structure calculations,we have studied the electronic and magnetic properties of the infinite-layer cuprate SrCuO_(2)from a phonon *** find that interesting fluctuations of charges,electrical dipoles,and local magnetic moments can be induced by the atomic displacements of phonon modes in SrCuO_(2)upon the hole *** all optical phonon modes of SrCuO_(2)in the antiferromagnetic Néel state,only the A_(1g)mode that involves the full-breathing O vibrations along the Cu-O bonds can cause significant fluctuations of local magnetic moments on O atoms and dramatic charge redistributions between Cu and O ***,due to the atomic displacements of the A_(1g)mode,both the charge fluctuations on Cu and the electrical dipoles on O show a dome-like evolution with increasing hole doping,quite similar to the experimentally observed behavior of the superconducting T_(c);in comparison,the fluctuations of local magnetic moments on O display a monotonic enhancement along with the hole *** analyses indicate that around the optimal doping,there exists a large softening in the frequency of the A_(1g)phonon mode and a van Hove singularity in the electronic structure close to the Fermi level,suggesting potential electron-phonon *** work reveals the important role of the full-breathing O phonon mode playing in the infinite-layer SrCuO_(2),which may provide new insights in understanding the cuprate superconductivity.

关键词： first-principles calculations cuprate superconductors phonon charge and spin fluctuations

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PCK1 attenuates tumor stemness via activating the Hippo signaling pathway in hepatocellular carcinoma

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Genes & Diseases 2024年第4期11卷 340-352页

作者： Rui Liu yi Liu Wenlu Zhang Guiji Zhang Zhirong Zhang Luyi Huang Ni Tang kai Wang Key Laboratory of Molecular Biology for Infectious Diseases(Ministry of Education) Institute for Viral HepatitisDepartment of Infectious DiseasesThe Second Affiliated HospitalChongqing Medical UniversityChongqing 400016China Department of Clinical Laboratory Sichuan Clinical Research Center for CancerSichuan Cancer Hospital&InstituteSichuan Cancer CenterAffiliated Cancer Hospital of University of Electronic Science and Technology of ChinaChengduSichuan 610041China

Liver cancer stem cells were found to rely on glycolysis as the preferred metabolic *** carboxylase 1(PCK1),a gluconeogenic metabolic enzyme,is down-regulated in hepatocellular carcinoma and is closely related to poor *** onco-genesis and progression of tumors are closely related to cancer stem *** is not completely clear whether the PCK1 deficiency increases the stemness of hepatoma cells and promotes the oncogenesis of hepatocellular ***,the results showed that PCK1 inhibited the self-renewal property of hepatoma cells,reduced the mRNA level of cancer stem cell markers,and inhibited ***,PCK1 increased the sensitivity of hepatocellular carci-noma cells to ***,we found that PCK1 activated the Hippo pathway by enhancing the phosphorylation of YAP and inhibiting its nuclear *** reduced the stemness of hepatoma cells and promoted the pro-apoptotic effect of ***,combined treatment with verteporfin and sorafenib may be a potential anti-tumor strat-egy in hepatocellular carcinoma.

关键词： Cancer stem cells Chemoresistance Gluconeogenesis Hepatocellular carcinoma YAP

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脑血管疾病风险人群湿证相关特征的流行病学调查

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广州中医药大学学报 2024年第3期41卷 531-539页

作者：倪小佳黄海燕苏晴徐曜刘玲玲邝卓然李一航张一开孟苗苗郭意欣杨小波蔡业峰广东省中医院脑病中心广东广州510120 广东省中医药科学院中医药防治脑血管病转化医学研究团队广东广州510120 广州中医药大学第二临床医学院广东广州510120 省部共建中医湿证国家重点实验室广东广州510120 黄培新广东省名中医传承工作室广东广州510120 广东省中医药科学院中医证候研究团队广东广州510120

【目的】探究广东地区脑血管疾病风险人群与中医湿证相关的流行病学特征。【方法】采用横断面研究的方法,调查330例广东常住居民脑血管疾病风险相关的临床资料,进行中医湿证诊断、量化评分及脑卒中风险评级,总结湿证分布规律并分析其影... 详细信息

【目的】探究广东地区脑血管疾病风险人群与中医湿证相关的流行病学特征。【方法】采用横断面研究的方法,调查330例广东常住居民脑血管疾病风险相关的临床资料,进行中医湿证诊断、量化评分及脑卒中风险评级,总结湿证分布规律并分析其影响因素。【结果】(1)诊断为湿证的研究对象共306例(占92.73%),风险组诊断为湿证人群的占比为93.82%(258/275),略高于健康组的87.27%(48/55),但差异无统计学意义(χ2=2.91,P=0.112),而风险组的湿证量化得分高于健康组,差异有统计学意义(Z=-2.24,P=0.025)。(2)在具有脑血管疾病危险因素的研究对象中,评价时间(χ2=26.11,P=0.001)、脑卒中风险等级(χ2=8.85,P=0.031)、脑卒中或短暂性脑缺血发作(TIA)病史(χ2=9.28,P=0.015)是脑血管病风险人群湿证等级的影响因素。【结论】湿证是广东地区人群常见的中医证候;具有脑血管疾病危险因素,尤其是脑卒中高风险人群、脑卒中或TIA病史患者,其湿证程度明显增高;未来在广东开展脑卒中预防工作应考虑湿证的评估与干预。

关键词：脑血管疾病脑卒中危险因素湿证流行病学调查广东地区

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Artificial stepwise light harvesting system in water constructed by quadruple hydrogen bonding supramolecular polymeric nanoparticles

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Chinese Chemical Letters 2024年第2期35卷 370-373页

作者： Tangxin Xiao Xiuxiu Li Liangliang Zhang kai Diao Zheng-yi Li Xiao-Qiang Sun Leyong Wang Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology School of Petrochemical EngineeringChangzhou UniversityChangzhou 213164China Jiangsu Key Laboratory of Advanced Organic Materials School of Chemistry and Chemical EngineeringNanjing UniversityNanjing 210023China

Stepwise energy transfer is ubiquitous in natural photosynthesis,which greatly promotes the widespread use of solar ***,we constructed a supramolecular light harvesting system based on sequential energy transfer through the hierarchical self-assembly of M,which contains a cyanostilbene core flanked by two ureidopyrimidinone motifs,endowing itself with both aggregation-induced emission behavior and quadruple hydrogen bonding *** monomer M can self-assemble into hydrogen bonded polymers and then form supramolecular polymeric nanoparticles in water through a mini-emulsion *** nanoparticles were further utilized to encapsulate the relay acceptor ESY and the final acceptor NDI to form a two-step FRET *** fluorescence including a white-light emission was successfully *** work not only shows a desirable way for the fabrication of efficient two-step light harvesting systems,but also shows great potential in tunable photoluminescent nanomaterials.

关键词： Light harvesting system Supramolecular polymer Quadruple hydrogen bonding AIE Self-assembly

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Prediction of Health Level of Multiform Lithium Sulfur Batteries Based on Incremental Capacity Analysis and an Improved LSTM

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Protection and Control of Modern Power Systems 2024年第2期9卷 21-31页

作者： Hao Zhang Hanlei Sun Le Kang yi Zhang Licheng Wang kai Wang School of Materials Science and Engineering Xi’an University of Architecture and Technology in Xi’anShanxi ProvinceChina School of Electrical Engineering Qingdao UniversityQingdao 266000China College of Materials Science and Engineering Xi’an University of Science and TechnologyXi’anShaanxi ProvinceChina School of Energy Sciences and Engineering Nanjing Tech UniversityNanjingJiangsu ProvinceChina School of Information Engineering Zhejiang University of TechnologyHangzhou provinceChina

Capacity estimation plays a crucial role in battery management systems,and is essential for ensuring the safety and reliability of lithium-sulfur(Li-S)*** paper proposes a method that uses a long short-term memory(LSTM)neural network to estimate the state of health(SOH)of Li-S *** method uses health features extracted from the charging curve and incre-mental capacity analysis(ICA)as input for the LSTM *** enhance the robustness and accuracy of the network,the Adam algorithm is employed to optimize specific *** data from three different groups of batteries with varying nominal capac-ities are used to validate the proposed *** results demonstrate the effectiveness of the method in accurately estimating the capacity degradation of all three ***,the study examines the impact of different lengths of network training sets on capacity *** results reveal that the ICA-LSTM model achieves a prediction accuracy of mean absolute error 4.6%and mean squared error 0.21%with three different training set lengths of 20%,40%,and 60%.The analysis demonstrates that the lightweight model maintains high SOH estimation accu-racy even with a small training set,and exhibits strong adaptive and generalization capabilities when applied to different Li-S ***,the proposed method,supported by experimental validation and analysis,demonstrates its efficacy in ensuring accurate and reliable SOH estimation,thereby enhancing the safety and per-formance of Li-S *** Terms—Adam algorithm,incremental capacity analysis,Li-S battery,long short-term memory,state of health.

关键词： Adam algorithm incremental capacity analysis Li-S battery long short-term memory state of health

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Coexistence of liver abscess, hepatic cystic echinococcosis and hepatocellular carcinoma: A case report

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World Journal of Clinical Cases 2024年第14期12卷 2404-2411页

作者： Ya-Wen Hu yi-Lin Zhao Jing-Xin Yan Cun-kai Ma Department of Interventional Therapy The Affiliated Hospital of Qinghai UniversityXining 810000Qinghai ProvinceChina West China Hospital Sichuan UniversityChengdu 610000Sichuan ProvinceChina

BACKGROUND Human cystic echinococcosis(CE)is a life-threatening zoonosis caused by the Echinococcus granulosus(sensu lato).Hepatocellular carcinoma(HCC)is a leading cause of cancer-related mortality in the *** coexistence of CE and HCC is exceedingly rare,and only several well-documented cases have been *** addition to this coexistence,there is no report of the coexistence of CE,HCC,and liver abscess to ***,we aimed to report a case of coexistence of liver abscess,hepatic CE,and *** SUMMARY A 65-year-old herdsman presented to the department of interventional therapy with jaundice,right upper abdominal distension and pain for 10 *** test showed that he had positive results for HBsAg,HBeAb,HBcAb,and echino-coccosis IgG *** test also showed an increased level of alpha fetopro-tein of 3400 ng/*** abdominal computed tomography(CT)scan revealed an uneven enhanced lesion of the liver at the arterial phase with enhancement and was located S4/8 segment of the *** addition,CT scan also revealed a mass in the S6 segment of the liver with a thick calcified wall and according to current guideline and medical images,the diagnoses of hepatic CE(CE4 subtype)and HCC were ***,transarterial chemoembolization was performed for *** the follow-up,liver abscess occurred in addition to CE and HCC;thus,percutaneous liver puncture drainage was *** the next follow-up,CE and HCC were *** liver abscess was completely resolved,and the patient was discharged with no evidence of *** This is the first reported case on the coexistence of liver abscess,hepatic CE,and *** treatment and multidisciplinary discussions should be performed in this ***,treatment and diagnosis should be based on the characteristics of liver abscess,hepatic CE,and HCC,and in future clinical work,it is necessary to be aware of the possibility of this complex composition of liver diseases.

关键词： Cystic echinococcosis Hepatocellular carcinoma Liver abscess Multidisciplinary discussions Case report

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Development of Wheel-Legged Biped Robots:A Review

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Journal of Bionic Engineering 2024年第2期21卷 607-634页

作者： Xuefei Liu yi Sun Shikun Wen kai Cao Qian Qi Xiaoshu Zhang Huan Shen Guangming Chen Jiajun Xu Aihong Ji Lab of Locomotion Bioinspiration and Intelligent Robots College of Mechanical and Electrical EngineeringNanjing University of Aeronautics and Astronautics29 Yudao StreetNanjing210016China State Key Laboratory of Mechanics and Control for Aerospace Structures Nanjing University of Aeronautics and AstronauticsNanjing210016China

The wheel-legged biped robot is a typical ground-based mobile robot that can combine the high velocity and high efficiency pertaining to wheeled motion and the strong,obstacle-crossing performance associated with legged *** robots have gradually exhibited satisfactory application potential in various harsh scenarios such as rubble rescue,military operations,and wilderness ***-legged biped robots are divided into four categories according to the open–close chain structure forms and operation task modes,and the latest technology research status is summarized in this *** hardware control system,control method,and application are analyzed,and the dynamic balance control for the two-wheel,biomimetic jumping control for the legs and whole-body control for integrating the wheels and legs are *** summary,it is observed that the current research exhibits problems,such as the insufficient application of novel materials and a rigid–flexible coupling design;the limited application of the advanced,intelligent control methods;the inadequate understanding of the bionic jumping mechanisms in robot legs;and the insufficient coordination ability of the multi-modal motion,which do not exhibit practical application for the wheel-legged biped ***,this study discusses the key research directions and development trends for the wheel-legged biped robots.

关键词： Wheel-legged biped robot Wheeled motion Legged motion Control strategy

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A study on the application of diffuse axonal multi-axis general evaluation for braininjury assessment in small overlap barrier crash test

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Chinese Journal of Traumatology 2024年第4期27卷 200-210页

作者： Zhi Fu yi Chang Tao Xiong Wen-kai Gao Kui Li Yu Liu China Automotive Engineering Research Institute Co. Ltd.Chongqing401122China Chongqing University of Technology Chongqing400054China Chongqing Key Laboratory of Vehicle Crash/Bio-Impact and Traffic Safety Chongqing400042China College of Medical Informatics Chongqing Medical UniversityChongqing400016China

Purpose:Head injury criterion(HIC)companied by a rotation-based metric was widely believed to behelpful for head injury prediction in road traffic ***,the Euro-New Car AssessmentProgram utilized a newly developed metric called diffuse axonal multi-axis general evaluation(DAMAGE)to explain test device for human occupant restraint(THOR)head injury,which demonstratedexcellent ability in capturing concussions and diffuse axonal ***,there is still a lack ofcomprehensive understanding regarding the effectiveness of using DAMAGE for Hybrid III 50thpercentile male dummy(H50th)head injury *** objective of this study is to determinewhether the DAMAGE could capture the risk of H50th brain injury during small overlap barrier ***:To achieve this objective,a total of 24 vehicle crash loading curves were collected as input datafor the multi-body *** commercially available mathematical dynamic models,namelyH50th and THOR,were utilized to investigate the differences in head injury ***,adecision method known as simple additive weighting was employed to establish a comprehensive braininjury metric by incorporating the weighted HIC and either DAMAGE or brain injury ***,35 sets of vehicle crash test data were used to analyze these brain injury ***:The rotational displacement of the THOR head is significantly greater than that of the *** maximum linear and rotational head accelerations experienced by H50th and THOR modelswere(544.6±341.7)m/s^(2),(2468.2±1309.4)rad/s^(2) and(715.2±332.8)m/s^(2),(3778.7±1660.6)rad/s^(2),*** the same loading condition during small overlap barrier(SOB)tests,THOR exhibits ahigher risk of head injury compared to the H50th *** was observed that the overall head injuryresponse during the small overlap left test condition is greater than that during the small overlap ***,an equation was formulated to establis

关键词： Diffuse axonal multi-axis general evaluation Head injury criterion Head injury assessment Small overlap barrier Biomechanical response

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The remarkable effect of amino hydrogen on membrane permeability and organelle staining of 1,8-naphthalimide dyes

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Chinese Chemical Letters 2024年第2期35卷 347-351页

作者： Zhifeng Li Qinglong Qiao Ning Xu kai An Wenchao Jiang yi Tao Pengjun Bao yinchan Zhang Zhaochao Xu School of Chemistry Dalian University of TechnologyDalian 116024China CAS Key Laboratory of Separation Science for Analytical Chemistry Dalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023China University of Chinese Academy of Sciences Beijing 100049China

Membrane permeability and intracellular diffusion of fluorescent probes determine staining selectivity of intracellular ***,the relationship between the molecular structure of fluorescent probes and their membrane permeability and intracellular distribution is poorly *** this paper,we reported a series of 1,8-naphthalimide dyes and carried out cell imaging experiments,and found that the presence of amino hydrogen in these dyes played a crucial role in their cell membrane permeability and intracellular *** secondary amino group containing compounds 1-4 show excellent membrane permeability and strong fluorescence in living *** the tertiary amine containing dyes 5 and 6 can hardly permeate the cell membrane though they show extremely similar structure with compounds *** 1 can selectively image lipid droplets by selecting the wavelength of excitation *** the specificity for lysosomes,2 and 4 have been used in long-term time-lapses imaging of lysosomal dynamics and tracking the process of lysosome-lysosome interaction,fusion and *** effect of hydrogen-containing amino substituent on the cell membrane permeability of fluorescent molecules is promising for the development of better biocompatible probes.

关键词： Amino hydrogen 1,8-Naphthalimide Cell permeability Lipid droplet Lysosome

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适用于嵌入式设备的轻量级深度学习网络RepYOLO

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湖北农业科学 2024年第8期63卷 153-157页

作者：周橄尉陈嘉越吴佳伟赵雅琪赵奕凯张小英山西农业大学信息科学与工程学院山西太谷030801 山西农业大学软件学院山西太谷030801

提出了一种轻量级深度学习网络模型RepYOLO算法,并将其移植到嵌入式设备MCU/MPU中。该网络模型RepYOLO以YOLOv4为基础网络模型,通过改进YOLOv4的主干网络CSPDarkNet为RepBlock结构、在Neck层中引入CBAM注意力机制以及在Head层替换anchor... 详细信息

提出了一种轻量级深度学习网络模型RepYOLO算法,并将其移植到嵌入式设备MCU/MPU中。该网络模型RepYOLO以YOLOv4为基础网络模型,通过改进YOLOv4的主干网络CSPDarkNet为RepBlock结构、在Neck层中引入CBAM注意力机制以及在Head层替换anchor-based检测头为anchor-free检测头并加入ATSS算法减小计算量、提高推理速度和检测精度。结果表明,与原YOLOv4模型相比,网络模型RepYOLO在小麦穗检测上表现出更显著的优势,其精度率、召回率、F1值和平均精度均值分别提高了4.7、3.6、1.5、1.7个百分点;此外,RepYOLO在嵌入式设备MCU/MPU上的推理时间分别降低了37.03%和41.44%。

关键词：目标检测深度学习嵌入式设备轻量级网络 RepYOLO 小麦穗

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