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Effect of Ti_(p) Content on the Work Hardening and Softening Behavior of Mg-Zn-Ca Alloy

Acta Metallurgica Sinica(English Letters) 2024年第3期37卷 551-560页

作者： jin-kai Zhang Cui-Ju Wang Yi-Dan Fan Chao Xu kai-Bo Nie Kun-Kun Deng Shanxi Key Laboratory of Advanced Magnesium-Based Materials College of Materials Science and EngineeringTaiyuan University of TechnologyTaiyuan 030024China School of Materials Science and Engineering Harbin Institute of TechnologyHarbin 150001China

The Ti_(p)/ZX60 composites with different Ti_(p) contents were prepared by semi-solid stirring *** extrusion,the microstructure,work hardening and softening behavior of the Ti_(p)/ZX60 composites were analyzed compared with the ZX60(Mg-6Zn-0.2Ca)*** results showed that the addition of Ti_(p) could not only promote the nucleation of dynamic recrystallized(DRXed)grains,but also be propitious to the refinement of DRXed *** increasing Ti_(p) content,the size of DRXed grains decreased accompanied with increasing volume fraction of DRXed *** the Ti_(p) content increased to 15 vol.%,the average size and volume fraction of DRXed grains reached to~0.32μm and 93.2%,***,both the strength and elongation were improved by the addition of Ti_(p).With increasing content of Ti_(p),a substantial increase in the strength was achieved with little change in the ***,the elongation decreased sharply when the Ti_(p) content further increased to 15 vol.%.The addition of Ti_(p) led to an increase in the work hardening rate,which gradually increased with increasing Ti_(p) ***,the softening rate did not demonstrate the same tendency with increasing Ti_(p) *** the conventional ceramic particles,the Ti_(p) can be deformed in coordination with the matrix alloy,which imparted a higher softening rate to the matrix *** though the softening rate improved as the Ti_(p) content increased from 5 to 10 vol.%,it dropped deeply as the Ti_(p) content increased to 15 vol.%owing to the fracture of Ti_(p) during extrusion.

关键词： Titanium particle content Particle reinforced magnesium matrix composites Work hardening Softening behavior Mechanical properties

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Transcriptome-based analysis of key signaling pathways affecting the formation of primordial germ cell in chickens

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Journal of Integrative Agriculture 2024年第5期23卷 1644-1657页

作者： Ying Ding Qiong Zhi Qisheng Zuo kai jin Wei Han Bichun Li Key Laboratory of Animal Genetics Breeding and Molecular Design of Jiangsu ProvinceCollege of Animal Science and TechnologyYangzhou UniversityYangzhou 225009China Joint International Research Laboratory of Agriculture and Agri-Product Safety of the Ministry of Education of China Yangzhou UniversityYangzhou225009China Poultry Research Institute Chinese Academy of Agricultural Sciences/Jiangsu Institute of Poultry ScienceYangzhou 225009China

Bone morphogenetic protein 4(BMP4)can induce the formation of chicken primordial germ cells(PGCs)in vitro;however,its regulatory mechanism in poultry remains *** study aimed to use RNA-seq to analyze PGCs in chicken embryos and iPGCs induced by BMP4 in vitro,clarify the internal regulatory factors of PGCs,analyze the mechanism of the formation of PGCs,and lay a theoretical foundation for the further optimization of PGCs induction *** stem cells(ESCs),PGCs and iPGCs induced by BMP4 in vitro were *** transcriptional maps of the three cell types were studied using *** results showed 6,142 genes differentially expressed between PGCs and iPGCs,of which 2,728 were upregulated in iPGCs and 3,414 were downregulated in *** to that in ESCs,BMP4 was significantly upregulated in PGCs and *** results showed that both the TGF-βand Wnt signaling pathways were activated during the formation of PGCs in vitro and in vivo,and the activation was more significant during iPGCs induced by *** expression of Nodal,an inhibitory factor of TGF-βsignaling,was significantly decreased in PGCs and iPGCs,but was not expressed in iPGCs,which further supports our ***,the Lysosome and PI3K-AKT signaling pathways were significantly enriched in PGCs and iPGCs,***,transmission electron microscopy(TEM)results showed that the number of autolysosomes was significantly higher after the addition of BMP4,which is consistent with the KEGG ***,the number of PGCs was significantly reduced after ATG14 was interfered in vivo and in *** conclusion,this study screened out the key signaling pathways during the formation of PGCs,aiming to provide help for enriching the mechanism network regulating PGCs formation in chicken and laying a theoretical foundation for further improving the efficiency of inducing PGCs in vitro.

关键词： RNA-seq BMP4 PGCs ATG14 chicken

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Examining the evolution of tidal creeks in the Huanghe River delta using multi-temporal Landsat images

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Journal of Oceanology and Limnology 2024年第4期42卷 1061-1073页

作者： Zhen HAN kai jin Quanli ZONG Peng QIN Chunxia LIU Xiuzhi ZHU Xinyue LI College of Resources and Environment Qingdao Agricultural UniversityQingdao 266109China

Coastal tidal creeks are important channels for exchanges of material and energy between sea and land,and play an important role in the ecological protection of tidal *** tidal creeks have evolved differently in various regions,the evolutionary process of tidal creeks in the Huanghe(Yellow)River delta of China,one of the most active deltas worldwide,is not entirely ***,the evolution of tidal creeks in the delta from 1981 to 2021 was investigated by quantitatively analysing the tidal creeks and developing a standard for dividing their evolution *** interpretation and supervised classification methods were applied to the Landsat images to extract the tidal creek network,and 17 groups of tidal creek systems were *** indicate that Creek S 1 was the most developed creek for having 113 tidal creeks totaling 65.8 km in length,while Creek E 3 had the fastest growth rate for having average annual increase of 1.9 ***,the level of tidal creeks increased,the average and median lengths of tidal creeks increased,and the number of tidal creeks decreased since *** evolution of the tidal creek system could be divided into four stages,namely,rising,developing,stabilizing,and *** of a representative tidal creek show that there was no degenerated tidal creek during the rising period,with an increase in the number of 50 and a length increase of 57.9 km between 1981 and *** proportion of new tidal creeks in the developing period was more than 50%and the new tidal creeks in the stabilizing period were equal to the degraded tidal *** tidal creeks were greater than 50%during the degrading *** was no fixed order of tidal creek evolution in each period,and there may be a skip in *** findings provided a reference for studying the evolution of tidal creeks.

关键词： tidal creek evolution pattern remote sensing Huanghe(Yellow)River delta

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Towards overcoming obstacles of type Ⅱ photodynamic therapy:Endogenous production of light,photosensitizer,and oxygen

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Acta Pharmaceutica Sinica B 2024年第3期14卷 1111-1131页

作者： Lin Yu Zhen Liu Wei Xu kai jin jinliang Liu Xiaohui Zhu Yong Zhang Yihan Wu Department of Chemical and Environmental Engineering Shanghai UniversityShanghai 200433China School of Medicine Shanghai UniversityShanghai 200433China Department of Biomedical Engineering City University of Hong KongHong KongChina

Conventional photodynamic therapy(PDT)approaches face challenges including limited light penetration,low uptake of photosensitizers by tumors,and lack of oxygen in tumor *** promising solution is to internally generate light,photosensitizers,and *** can be accomplished through endogenous production,such as using bioluminescence as an endogenous light source,synthesizing genetically encodable photosensitizers in situ,and modifying cells genetically to express catalase ***,these strategies have been reinforced by the recent rapid advancements in synthetic *** this review,we summarize and discuss the approaches to overcome PDT obstacles by means of endogenous production of excitation light,photosensitizers,and *** envision that as synthetic biology advances,genetically engineered cells could act as precise and targeted“living factories”to produce PDT components,leading to enhanced performance of PDT.

关键词： Photodynamic therapy Cancer Biogenesis Biosynthesis Engineered bacteria Phototherapy Photosensitizers Catalase

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Spectral observation of symmetry-protected selection rules for dynamical high-dimensional parity in alignment magnetic resonance

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Science China(Physics,Mechanics & Astronomy) 2024年第10期Mechanics & Astronomy) .卷 5-15页

作者： Xu-Xing Geng kai jin Lu Zhou Wang-Wang Tang Guoqing Yang Shangqing Liang Shao-Ping Wu Guang-Ming Huang Gao-Xiang Li Department of Physics Huazhong Normal University State Key Laboratory of Precision Spectroscopy School of Physics and Electronic ScienceEast China Normal University College of Electronics and Information Hangzhou Dianzi University

Multidimensional Floquet-driven alignment systems with dynamical symmetry present various exotic phenomena and applications. However, there are challenges in directly characterizing large-spin dynamical symmetry from spectra. Here, we first observe the symmetry-protected selection rules of dynamical high-dimensional parity in a large-spin(F = 4) system. We theoretically construct a Floquet-driven alignment system that can be used to reveal high-dimensional spatiotemporal symmetry. In the experiment, the system is implemented in Cs atomic gas subjected to two-dimensional Floquet-modulated magnetic resonance driving. By developing Floquet detection protocols of alignment double-sided spectra, we directly verify symmetry-protected selection rules of dynamical high-dimensional parity for large-spin systems. This work advances the exploration of dynamical symmetry to large spins, and unravels a universal Floquet scheme for the investigation of symmetry-protected selection rules.

关键词： dynamical high-dimensional symmetry symmetry-protected selection rules large-spin alignment magnetic resonance Floquet two-mode detection

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Semaphorin 7A impairs barrier function in cultured human corneal epithelial cells in a manner dependent on nuclear factor-kappa B

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International Journal of Ophthalmology(English edition) 2024年第3期17卷 444-453页

作者： Cheng-Cheng Yang Xiu-Xia Yang Xiao-jing Zhao Heng Wang Zi-Han Guo kai jin Yang Liu Bin-Hui Li Department of Ophthalmology the Fifth Affiliated HospitalSun Yat-sen UniversityZhuhai 519000Guangdong ProvinceChina Department of Ophthalmology Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical UniversityHangzhou 310006Zhejiang ProvinceChina Eye Institute of Xiamen University Fujian Provincial Key Laboratory of Ophthalmology and Visual ScienceSchool of MedicineXiamen UniversityXiamen 361005Fujian ProvinceChina

●AIM:To evaluate the role of semaphorin 7A(Sema7A)and its associated regulatory mechanisms in modulating the barrier function of cultured human corneal epithelial cells(HCEs).●METHODS:Barrier models of HCEs were treated with recombinant human Sema7A at concentrations of 0,125,250,or 500 ng/mL for 24,48,or 72h in *** electrical resistance(TEER)as well as Dextran-fluorescein isothiocyanate(FITC)permeability assays were conducted to assess barrier *** quantify tight junctions(TJs)such as occludin and zonula occludens-1(ZO-1)at the mRNA level,reverse transcriptionpolymerase chain reaction(RT-PCR)analysis was *** was used to examine the activity of the nuclear factor-kappa B(NF-κB)signaling pathway and the production of TJs *** analyses were employed to localize the ***-linked immunosorbent assay(ELISA)and RT-PCR were utilized to observe changes in interleukin(IL)-1β*** investigate the role of NF-κB signaling activation and IL^(-1)βin Sema7A’s anti-barrier mechanism,we employed 0.1μmol/L IκB kinase 2(IKK2)inhibitor IV or 500 ng/mL IL^(-1)receptor(IL-1R)antagonist.●RESULTS:Treatment with Sema7A resulted in decreased TEER and increased permeability of Dextran-FITC in HCEs through down-regulating mRNA and protein levels of TJs in a time-and dose-dependent manner,as well as altering the localization of ***,Sema7A stimulated the activation of inhibitor of kappa B alpha(IκBα)and expression of IL-1β.The anti-barrier function of Sema7A was significantly suppressed by treatment with IKK2 inhibitor IV or IL-1R antagonists.●CONCLUSION:Sema7A disrupts barrier function through its influence on NF-κB-mediated expression of TJ proteins,as well as the expression of IL-1β.These findings suggest that Sema7A could be a potential therapeutic target for the diseases in corneal epithelium.

关键词： human corneal epithelial barrier function transepithelial electrical resistance zonula occludens-1 occludin nuclear factor-kappa B

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合成孔径激光雷达成像技术研究进展

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光电工程 2024年第3期51卷 29-49页

作者：徐晨晋凯魏凯自适应光学全国重点实验室四川成都610209 中国科学院光电技术研究所四川成都610209 浙江大学光电科学与工程学院浙江杭州310058 极端光学技术与仪器全国重点实验室浙江杭州310058

合成孔径激光雷达成像技术是一种能够突破光学系统衍射极限的主动光学成像技术,其概念来自工作在微波波段的合成孔径雷达,相比于合成孔径雷达,合成孔径激光雷达具有成像速度快、成像分辨率高以及能获取符合人眼感知的图像的优势,在远距... 详细信息

合成孔径激光雷达成像技术是一种能够突破光学系统衍射极限的主动光学成像技术,其概念来自工作在微波波段的合成孔径雷达,相比于合成孔径雷达,合成孔径激光雷达具有成像速度快、成像分辨率高以及能获取符合人眼感知的图像的优势,在远距离目标感知与识别中具有很高的潜在价值。本文从合成孔径激光雷达的工作原理出发,回顾和梳理了合成孔径激光雷达的主要关键技术的主要进展,包括合成孔径激光雷达的系统模型和基础理论、系统设计与架构、激光相位噪声抑制、运动补偿技术以及成像算法;同时对国内外重要的外场实验进展进行了总结。最后探讨了后续实现工程化所需面对的困难和挑战。

关键词：主动光学成像技术合成孔径激光雷达相干激光雷达计算成像

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Internal phase control of fiber laser array based on photodetector array

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Chinese Physics B 2024年第7期33卷 320-326页

作者：靳凯凯龙金虎常洪祥粟荣涛张嘉怡陈思雨马阎星周朴 College of Advanced Interdisciplinary Studies National University of Defense TechnologyChangsha 410073China Nanhu Laser Laboratory National University of Defense TechnologyChangsha 410073China Hunan Provincial Key Laboratory of High Energy Laser Technology National University of Defense TechnologyChangsha 410073China

Coherent beam combining(CBC) of fiber laser array is a promising technique to realize high output power while maintaining near diffraction-limited beam quality. To implement CBC, an appropriate phase control feedback structure should be established to realize phase-locking. In this paper, an innovative internal active phase control CBC fiber laser array based on photodetector array is proposed. The dynamic phase noises of the laser amplifiers are compensated before being emitted into free space. And the static phase difference compensation of emitting laser array is realized by interference measurement based on photodetector array. The principle of the technique is illustrated and corresponding simulations are carried out, and a CBC system with four laser channels is built to verify the technique. When the phase controllers are turned on, the phase deviation of the laser array is less than λ/20, and ~ 95% fringe contrast of the irradiation distribution is obtained. The technique proposed in this paper could provide a reference for the system design of a massive high-power CBC system.

关键词： fiber laser laser array coherent beam combining internal phase control

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新质生产力视角下的未来产业发展:内涵特征与发展思路

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技术经济与管理研究 2024年第3期 1-6页

作者：王鹏靳开颜北京市社会科学院管理研究所北京100101

新质生产力以新产业发展为主导,以产业升级为方向,以科技创新引领产业全面振兴。它既是指引产业格局发展的核心生产力,也是提升经济发展的核心竞争力。为加快新质生产力应用的广泛普及,需要广纳科技人才,以科技创新推动产业创新,以产业... 详细信息

新质生产力以新产业发展为主导,以产业升级为方向,以科技创新引领产业全面振兴。它既是指引产业格局发展的核心生产力,也是提升经济发展的核心竞争力。为加快新质生产力应用的广泛普及,需要广纳科技人才,以科技创新推动产业创新,以产业升级构筑新的竞争优势。同时,需要构建高效的制度框架,统筹好新质生产力与未来产业的关系,在产业转型升级过程中做好牵引与衔接工作。当前,我国正处于实现中华民族伟大复兴的关键时期,面对科技革命与产业变革加速演化的现状,中国需要培育和发展新质生产力,增强经济发展新动能,进而推动未来经济的高质量发展,提高中国的国际竞争力。未来,通过不断的创新实践,中国经济将更好地适应与影响全球经济发展,真正实现数字化经济转型。

关键词：新质生产力科技创新未来产业发展高质量发展

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黄河三角洲典型潮沟发育演变过程分析

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水利水电科技进展 2024年第4期44卷 38-44页

作者：韩震宗全利金凯祝秀芝青岛农业大学资源与环境学院山东青岛266109

以黄河三角洲东部、侧弯丁坝北部为研究区域,基于1997—2021年内共8期Landsat系列遥感影像,采用目视解译的方法提取潮沟网络,通过分析不同时期潮沟数量、长度、密度等特征,揭示了潮沟阶段性演变规律。结果表明:潮沟的全生命周期可划分... 详细信息

以黄河三角洲东部、侧弯丁坝北部为研究区域,基于1997—2021年内共8期Landsat系列遥感影像,采用目视解译的方法提取潮沟网络,通过分析不同时期潮沟数量、长度、密度等特征,揭示了潮沟阶段性演变规律。结果表明:潮沟的全生命周期可划分为幼年期、青年期、成熟期和退化期4个阶段,其中幼年期潮沟数量和长度增长率最大,是青年期的3倍以上;青年期潮沟数量和长度继续增加,但增长率明显降低,潮沟网络系统逐渐趋于稳定;成熟期潮沟系统发育基本完成,潮沟长度、数量、曲率等形态特征无明显变化;退化期部分潮沟萎缩、消亡、废弃,2005—2007年Ⅰ组潮沟每年消亡10.8%。

关键词：黄河三角洲潮沟发育演变时空特征

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