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Acupuncture as a bioinformatics science and a proposal for the recognition of a new law of nature “Law of therapeutic neuromodulation”

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Journal of Biomedical Science and Engineering 2012年第10期5卷 597-601页

作者： Andrés A. zuno-Arce Carlos U. Haubi-Segura Departamento de Disciplinas Pecuarias Universidad Autónoma de Aguascalientes Aguascalientes México Universidad Candegabe de Homeopatía Argentina

Brain, an organ similar to a computer, is the ultimate director of the body1. This means that organs, tissues and cells are under its control and that these parts of the body do not control what happen to them. if the brain is functioning properly, we have health;and if it works wrongly a disease will show. Acting on the brain by neuromodulation, by means of acupuncture, homeopathy or even allopathic drugs can produce a therapeutic response. The purpose of this paper is to recognize this effect and propose a new Law of Cure which explains how several complementary and alternative medicine (CAM) systems work. in this theory, acupuncture works by stimulating peripheral sensory receptors and transmitting information to the brain which in turn will trigger a curative response to the affected organ. in this sense, acupuncture is an informatics system for a biological system, and therefore it could be considered part of the bioinformatics sciences, in the same idea that the brain is a living computer which has inputs and outputs and controls all process inside the body. in this paper we present the basis for this theory.

关键词： Acupuncture Bioinformatics Central Nervous System Computer Brain Therapeutic Neuromodulation Law of Nature

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improved Analytical Methods for Determination of Residues of Nitrapyrin and 6-Chloropicolinic Acid in Different Crop Matrices by Liquid Chromatography-Tandem Mass Spectrometry

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Journal of Agricultural Chemistry and Environment 2024年第3期13卷 263-281页

作者： Fabiola G. zuno-Floriano Riza L. Reyes-Punongbayan Matt J. Hengel Department of Environmental Toxicology University of California Davis California USA

Novel analytical methods were developed for the determination of nitrapyrin and 6-chloropicolinic acid (6-CPA) residues in agricultural products. Nitrapyrin was extracted with hexane: toluene (1:1, v/v) and 6-CPA with 0.1 N sodium hydroxide (NaOH). For nitrapyrin, samples were cleaned with silica solid phase extraction (SPE) and for 6-CPA with C18 or carbon SPE. Analysis was performed by liquid chromatography-tandem mass spectroscopy (LC-MS/MS) with external calibration (0.010 to 0.0010 µg∙mL−1 for nitrapyrin and 0.0050 to 0.00025 µg∙mL−1 for 6-CPA). Recoveries for nitrapyrin and 6-CPA were 68% - 102% and 66% - 90%, respectively. Nitrapyrin was detected in celery and onion (−1) and 6-CPA in onion, mustard greens and lettuce (−1). Lower level method validation (LLMV) for nitrapyrin and 6-CPA was 0.020 µg∙g−1 and 0.050 µg∙g−1, respectively. The methods presented in this study are robust and were utilized for the registration of nitrapyrin on agricultural commodities in the United States.

关键词： Herbicide Agricultural Products External Calibration LC-MS/MS Registration

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