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香椿的树木年轮宽度与超年生殖行为的相互关系:对树轮学研究的警示

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Journal of Plant Ecology 2024年第1期17卷 165-171页

作者： Monique silva Costa Thaís Jorge de Vasconcellos Claudio sergio Lisi Arno fritz Neves Brandes Mario Tomazello-Filho Cátia Henriques Callado Instituto de Aplicação Fernando Rodrigues da silveira Universidade do Estado do Rio de JaneiroRua Barão de Itapagipe96.Rio Comprido 20261-005Rio de JaneiroBrazil Laboratório de Anatomia Vegetal Universidade do Estado do Rio de JaneiroRua São Francisco Xavier524Maracanã20550-013Rio de JaneiroBrazil Departamento de Biologia Universidade Federal de SergipeAv.Marechal Rondon s/n-Rosa Elze.São Cristóvão 49100-000SergipeBrazil Departamento de Biologia Geral Universidade Federal FluminenseRua Prof.Marcos Waldemar de Freitas ReisS/N.Gragoatá24210-201Rio de JaneiroBrazil Escola superior de Agricultura Luiz de Queiroz Universidade de São PauloAv.Pádua Dias11.Piracicaba 13418-900São PauloBrazil

资源分配到生殖过程涉及到生态和进化因素,可能会减少植物的营养生长。这种相互关系在自然界中不容易观察到,因为有许多参数可以限制生殖结构的产生或生物量的增加。我们将香椿(Cedrela odorata L.,楝科)在里约热内卢州大西洋森林中的... 详细信息

资源分配到生殖过程涉及到生态和进化因素,可能会减少植物的营养生长。这种相互关系在自然界中不容易观察到,因为有许多参数可以限制生殖结构的产生或生物量的增加。我们将香椿(Cedrela odorata L.,楝科)在里约热内卢州大西洋森林中的树木年轮宽度与超年生殖行为相关联。总体而言,生殖结构的发育发生在湿润的年份,在生长季初期没有出现水分亏缺。然而,在这些年份,树木年轮宽度较小。这些结果可能与树木年轮宽度与当地气候之间缺乏相关性有关。因此,我们强调在径向生长研究中纳入生殖数据的重要性,以扩大对热带森林生长变异性的理解。

关键词：植物生长策略树木年轮学树木生态学生殖权衡

Ca^(2+) binding to the C_(2)E domain of otoferlin is required for hair cell exocytosis and hearing

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Protein & Cell 2024年第4期15卷 305-312页

作者： Han Chen Mehar Monga Qinghua Fang Loujin slitin Jakob Neef shashank s.Chepurwar Regina Célia Mingroni Netto karina Lezirovitz Alfredo Tabith,Jr. fritz Benseler Nils Brose kathrin kusch Carolin Wichmann Nicola strenzke Barbara Vona Julia Preobraschenski Tobias Moser Institute for Auditory Neuroscience and InnerEarLab University Medical Center Göttingen37075 GöttingenGermany Collaborative Research Center 889 University of Göttingen37075 GöttingenGermany Auditory Neuroscience and synaptic Nanophysiology Group Max Planck Institute for Multidisciplinary Sciences37075 GöttingenGermany Göttingen Graduate Center for Neurosciences Biophysics and Molecular BiosciencesUniversity of Göttingen37075 GöttingenGermany Biochemistry of Membrane Dynamics Group Institute for Auditory NeuroscienceUniversity Medical Center Göttingen37075 GöttingenGermany Molecular Architecture of synapses Group Institute for Auditory Neuroscience and InnerEarLabUniversity Medical Center Göttingen37075 GöttingenGermany Center for Biostructural Imaging of Neurodegeneration University Medical Center Göttingen37075 GöttingenGermany Auditory systems Physiology Group Institute for Auditory Neuroscience and InnerEarLabUniversity Medical Center Göttingen37075 GöttingenGermany Departamento de Genética e Biologia Evolutiva Centro de Pesquisas sobre o Genoma Humano e Células-TroncoInstituto de BiociênciasUniversidade de São PauloSão Paulo 05508-220Brazil Laboratório de Otorrinolaringologia/LIM32 Faculdade de MedicinaHospital das ClínicasUniversidade de São PauloSão PauloSP 05508-220Brazil DERDIC Pontifícia Universidade Católica de São PauloSão Paulo 05508-220Brazil Department of Molecular Neurobiology Max Planck Institute for Multidisciplinary Sciences37075 GöttingenGermany Multiscale Bioimaging Cluster of Excellence(MBExC) University of Göttingen37075 GöttingenGermany Functional Auditory Genomics Group Auditory Neuroscience and Optogenetics LaboratoryGerman Primate Center37077 GöttingenGermany Hearing Genomics Group Institute for Auditory Neuroscience and InnerEarLabUniversity Medical Center Göttingen37075 GöttingenGermany Institute of Human Genetics University Medical Center Göttingen37075 GöttingenGermany

Dear Editor,Afferent synapses of cochlear inner hair cells(IHCs)employ a unique molecular machinery(see extended background in supplementary Materials).Otoferlin is a key player in this machinery and its defects cause human auditory synaptopathy(Moser and starr,2016).Otoferlin,a tail-anchored(Vogl et al.,2016)multi-C_(2)-domain protein(Fig.1Ai)specific to hair cells(Roux et al.,2006),is a member of the ferlin protein family involved in membrane trafficking and repair that are of major disease relevance(Pangršičet al.,2012),also see supplementary *** is distributed broadly within IHCs(Fig.2Ai-Aiii;Pangrsic et al.,2010;Roux et al.,2006).

关键词： auditory hair

Advancing proteomics and machine learning in the clinic:an editorial on“Noninvasive proteomic biomarkers for alcohol-related liver disease”

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Hepatobiliary surgery and Nutrition 2022年第5期11卷 762-765页

作者： Courtney D.McGinnis Brenton I.M.Graham Peter s.Harris k.istofer s.fritz skaggs school of Pharmacy and Pharmaceutical sciences University of Colorado Anschutz Medical CampusAuroraCOUSA

Alcohol-associated liver disease(ALD)is increasingly prevalent throughout the world(1).It remains the leading cause of liver-related morbidity and mortality worldwide and contributes to approximately 6%of global deaths(2).ALD encompasses a wide range of hepatic pathologies,including steatosis,steatohepatitis,fibrosis,and cirrhosis(3).Given the severe lack of therapeutic interventions available to reverse the progression of ALD,it is currently the leading indication for liver transplantation(4).Advancements within the field are needed to identify diagnostic biomarkers for early detection and to develop therapeutics to ameliorate hepatic dysfunction and pathologies associated with ALD.

关键词： hepatic liver mortality

In situ nanoscale mapping of electrical and catalytic properties

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National science Review 2024年第7期11卷 65-66页

作者： Christopher s.kley Helmholtz Young Investigator Group Nanoscale Operando CO2 Photo-Electrocatalysis Helmholtz-Zentrum Berlin für Materialien und Energie GmbH Department of Interface science Fritz Haber Institute of the Max Planck Society

By enabling the conversion of sustainably-derived electrical energy into chemical energy, electrocatalytic reactions are vital for closing the anthropogenic carbon cycle. A wide array of electrocatalytic reactions have gained extensive attention, including hydrogen evolution（HER）, oxygen evolution（OER）, and CO2electroreduction（CO2RR）.

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Magnetic Moment Tensor Potentials for collinear spin-polarized materials reproduce different magnetic states of bcc Fe

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npj Computational Materials 2022年第1期8卷 107-112页

作者： Ivan Novikov Blazej Grabowski fritz körmann Alexander shapeev skolkovo Institute of science and Technology Skolkovo Innovation CenterNobel St.3Moscow143026Russia Institute for Materials science University of StuttgartPfaffenwaldring 5570569StuttgartGermany Computational Materials Design Max-Planck-Institut für Eisenforschung GmbHD-40237DüsseldorfGermany Materials science and Engineering Delft University of Technology2628 CDDelftThe Netherlands

We present the magnetic Moment Tensor Potentials(mMTPs),a class of machine-learning interatomic potentials,accurately reproducing both vibrational and magnetic degrees of freedom as provided,e.g.,from first-principles *** accuracy is achieved by a two-step minimization scheme that coarse-grains the atomic and the spin *** performance of the mMTPs is demonstrated for the prototype magnetic system bcc iron,with applications to phonon calculations for different magnetic states,and molecular-dynamics simulations with fluctuating magnetic moments.

关键词： magnetic fluctuating states

Impact of lattice relaxations on phase transitions in a high-entropy alloy studied by machine-learning potentials

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npj Computational Materials 2019年第1期5卷 670-676页

作者： Tatiana kostiuchenko fritz körmann Jörg Neugebauer Alexander shapeev skolkovo Institute of science and Technology Skolkovo Innovation CenterNobel St.3Moscow 143026Russia Computational Materials Design Max-Planck-Institut für Eisenforschung GmbH40237 DüsseldorfGermany Materials science and Engineering Delft University of Technology2628 CD DelftThe Netherlands

Recently,high-entropy alloys(HEAs)have attracted wide attention due to their extraordinary materials properties.A main challenge in identifying new HEAs is the lack of efficient approaches for exploring their huge compositional *** initio calculations have emerged as a powerful approach that complements ***,for multicomponent alloys existing approaches suffer from the chemical complexity *** this work we propose a method for studying HEAs *** approach is based on the application of machine-learning potentials based on ab initio data in combination with Monte Carlo *** high efficiency and performance of the approach are demonstrated on the prototype bcc NbMoTaW *** approach is employed to study phase stability,phase transitions,and chemical short-range *** importance of including local relaxation effects is revealed:they significantly stabilize single-phase formation of bcc NbMoTaW down to room ***,a so-far unknown mechanism that drives chemical order due to atomic relaxation at ambient temperatures is discovered.

关键词： alloy relaxation entropy

Chemically induced local lattice distortions versus structural phase transformations in compositionally complex alloys

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npj Computational Materials 2021年第1期7卷 312-319页

作者： Yuji Ikeda konstantin Gubaev Jörg Neugebauer Blazej Grabowski fritz körmann Institute for Materials science University of StuttgartStuttgartGermany Max-Planck-Institut für Eisenforschung GmbH DüsseldorfGermany Department of Materials science and Engineering Delft University of TechnologyDelftThe Netherlands

Recent experiments show that the chemical composition of body-centered cubic(bcc)refractory high entropy alloys(HEAs)can be tuned to enable transformation-induced plasticity(TRIP),which significantly improves the ductility of these *** calls for an accurate and efficient method to map the structural stability as a function of composition.A key challenge for atomistic simulations is to separate the structural transformation between the bcc and theωphases from the intrinsic local lattice distortions in such chemically disordered *** solve this issue,we develop a method that utilizes a symmetry analysis to detect differences in the crystal *** this method in combination with ab initio calculations,we demonstrate that local lattice distortions largely affect the phase stability of Ti–Zr–Hf–Ta and Ti–Zr–Nb–Hf–Ta *** relaxation effects are properly taken into account,the predicted compositions near the bcc–hcp energetic equilibrium are close to the experimental compositions,for which good strength and ductility due to the TRIP effect are observed.

关键词： alloys ductility distortion

Assessing the Efficacy of Lemongrass (Cymbopogon citratus) and sambong (Blumea balsamifera) Extracts in Combating Black Pod Disease: sustainable solutions for Controlling Phytophthora megakarya in Cameroon’s Cocoa Plantations

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American Journal of Plant sciences 2024年第7期15卷 519-537页

作者： Gertrude Membang James Michel Tchotet Tchoumi Godswill Ntsomboh Ntsefong Emmanuel Yvan Mba Ela sylvere Landry Lontsi Dida Ludovic Tchuenkam Tsango Pascal Loïc Ekango Mbondjo fritz Oben Tabi Innovative Plant Health Laboratory Faculty of Agronomy and Agricultural Sciences (FASA)-Bafia Annex University of Dschang Dschang Cameroon IDepartment of Plant Biology Faculty of Science University of Yaounde 1 Yaounde Cameroon Laboratory of Phytopathology and Crop Protection Faculty of Sciences University of Yaounde 1 Yaounde Cameroon Department of soil science Faculty of Agronomy and Agricultural Sciences (FASA) University of Dschang Dschang Cameroon

The use of plant extracts as antifungal agents is gaining increasing attention, particularly for the control of black pod disease in cocoa. Despite extensive research, current strategies haven’t been entirely effective. This study evaluated the effectiveness of Cymbopogon citratus and Blumea balsamifora leaf extracts, both individually and in combination, against Phytophthora megakarya. We assessed the efficacy of the most promising combination (75% B. balsamifera, 25% C. citratus) after storage at room temperature for up to 9 days. Agar microdilution and in vivo bioassays were conducted to determine antifungal susceptibility and effectiveness. Blumea extract exhibited the highest overall inhibitory activity, with the lowest minimum inhibitory concentration (117 µl mL−1) while C. citratus had a narrower range of MIC (146 to 233 µl mL−1). The combination of C. citratus and B. balsamifera demonstrated a synergistic effect against P. megakarya, achieving growth inhibition on V8 media (92.72 ± 4.20% to 100%) and on artificially infected detached pod cortex (92.24 ± 4.53% to 98.75 ± 1.25%), which was not significantly different from the positive control (Ridomil). Furthermore, this combination maintained its effectiveness for up to 9 days at room temperature. These findings suggest that combining plant extracts can enhance their antifungal properties.

关键词： Plant Extracts Antifungal Agents synergistic Effect Black Pod Disease Cocoa

Temperature-dependent phonon spectra of magnetic random solid solutions

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npj Computational Materials 2018年第1期4卷 606-612页

作者： Yuji Ikeda fritz körmann Biswanath Dutta Abel Carreras Atsuto seko Jörg Neugebauer Isao Tanaka Department of Materials science and Engineering Kyoto UniversityKyoto 606-8501Japan Center for Elements strategy Initiative for structural Materials(EsIsM) Kyoto UniversityKyoto 606-8501Japan Max-Planck-Institut für Eisenforschung GmbH D-40237 DüsseldorfGermany Department of Materials science and Engineering Delft University of TechnologyMekelweg 22628 CD DelftNetherlands Precursory Research for Embryonic science and Technology(PREsTO) Japan Science and Technology Agency(JST)Kawaguchi 332-0012Japan Center for Materials Research by Information Integration National Institute for Materials Science(NIMS)Tsukuba 305-0047Japan Nanostructures Research Laboratory Japan Fine Ceramics CenterNagoya 456-8587Japan

A first-principles-based computational tool for simulating phonons of magnetic random solid solutions including thermal magnetic fluctuations is *** method takes fluctuations of force constants due to magnetic excitations as well as due to chemical disorder into *** developed approach correctly predicts the experimentally observed unusual phonon hardening of a transverse acoustic mode in Fe–Pd an Fe–Pt Invar alloys with increasing *** peculiar behavior,which cannot be explained within a conventional harmonic picture,turns out to be a consequence of thermal magnetic *** proposed methodology can be straightforwardly applied to a wide range of materials to reveal new insights into physical behaviors and to design materials through computation,which were not accessible so far.

关键词： magnetic random phonon