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Treatment of in stent coronary restenosis with excimer laser angioplasty

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Chinese Medical Journal 2000年第1期113卷 14-17页

作者： Meilin Liu W.H.Chow O.H.kwok M.H.Jim A.Yip k.fan E.Chan Department of Cardiology First Teaching HospitalBeijing Medical UniversityBeijing 100034China Cardiac Medical Unit Grantham HospitalHong KongChina

OBJECTIVE: To evaluate the efficacy and safety of excimer laser coronary angioplasty (ELCA) with adjunctive balloon angioplasty in patient with in-stent restenosis. METHODS: ELCA was performed in 20 patients of instent restenosis. All patients were symptomatic and had class III-IV angina. ELCA was performed with the Spectranetics CVX-300 System. The laser catheter of Vittesse C (concentric) and E (eccentric) with diameter of 1.4-2.0 mm was used. RESULTS: Laser catheter crossed all stenotic stents without difficulty. The lesion length was 4.6-51.2 mm, mean 20.7 +/- 13.7 mm, including 14 lesions > 10 mm. Laser treatment alone increased minimal lumen diameter (MLD) from 0.3 +/- 0.3 mm to 1.4 +/- 0.3 mm (P

关键词： Angioplasty, Balloon, Laser-Assisted Stents Aged Aged, 80 and over Angioplasty, Transluminal, Percutaneous Coronary Coronary Restenosis Female Humans Male Middle Aged

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不同构形群桩的动力反应

世界地震工程 1994年第4期10卷 55-60页

作者： G.Gazetas k.fan A.kaynia 徐晶

一、前言土—桩—基础—结构系统的地震相互作用分析可以按下列三步依次进行: (1)求不计上部结构惯性的基础运动。这一所谓的基础输入运动包括平移分量和旋转分量; (2)确定桩帽平移、旋转和平移旋转耦合振动的动力阻抗函数(弹簧、阻尼... 详细信息

一、前言土—桩—基础—结构系统的地震相互作用分析可以按下列三步依次进行: (1)求不计上部结构惯性的基础运动。这一所谓的基础输入运动包括平移分量和旋转分量; (2)确定桩帽平移、旋转和平移旋转耦合振动的动力阻抗函数(弹簧、阻尼器); (3)计算支承在上述弹簧、阻尼器上的上部结构的地震反应,其基底输入为由第一步所获得的基础运动。对于上述分析的每一步骤,都已提出了多种可供选择的计算方法。

关键词：桩基础群桩动力反应

EGFR signaling augments TLR4 cell surface expression and function in macrophages via regulation of Rab5a activation

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Protein & Cell 2020年第8期11卷 144-149页

作者： Jing Tang Bowei Zhou Melanie JScott Linsong Chen Dengming Lai Erica kfan Yuehua Li Qiang Wu Timothy RBilliar Mark AWilson Ping Wang Jie fan The Department of Anesthesiology Affiliated hospital of Guangdong Medical UniversityZhanjiang 524000China Department of Surgery University of Pittsburgh School of MedicinePittsburghPA 15213USA Research and Development Veterans Affairs Pittsburgh Healthcare SystemPittsburghPA 15240USA Department of Anesthesiology Nanfang HospitalSouthern Medical UniversityGuangzhou 510515China Department of Thoracic Surgery Shanghai Pulmonary HospitalTongji University School of MedicineShanghai 200433China Department of Cardiovascular Surgery The Children's Hospital of Zhejiang University School of MedicineHangzhou 310052China University of Pittsburgh The Graduate School of Public Health PittsburghPA 15213USA Laboratory of Tropical Biomedicine and Biotechnology School of Tropical Medicine and Laboratory MedicineHainan Medical UniversityHaikou 571199China The Feinstein Institute for Medical Research ManhassetNY 11030USA McGowan Institute for Regenerative Medicine University of PittsburghPittsburghPA 15219USA key Laboratory of Organ Injury/Protection and Translational Medicine of Zhanjiang Zhanjiang 524000China

Dear Editor,oll-like receptor 4(TLR4)is a key receptor sensing bacterial lipopolysaccharide(LPS),and is the most investigated member of the Tol-like receptor family(kawai and Akira,2007;kayagaki et al,2013;klein et al.,2015).Cell surface TLR4 expression is determined by the balance between receptor trafficking from the Golgi apparatus to the cell membrane,and internalization of the cell surface receptor into endosomal compartments(Saltoh,2009).In bone mar-row-derived macrophages(BMDM),we observed LPS-in-duced EGFR phosphorylation on the surface of BMDM,and this was inhibited by pretreatment with PD168393 or TAPI-1(Fig.S1).Next,we measured dynamic changes in cell sur-face TLR4 expression after LPS ***6,12,and 24 h after LPS treatment,TLR4 expression on the surface of BMDM was increased^2-,~6-,and^9-fold,respectively,as compared with controls.

关键词： PD1 TLR4 inhibited

Tackling the microlensing wave effects of strong lensing gravitational waves with TAAH

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 257-258页

作者： Zuhui fan South-Western Institute for Astronomy Research Yunnan University

The rapid development of gravitational wave（GW） observations since their first detection in 2015 [1] has opened a completely new window for exploring the Universe. Consequently, astronomical research has entered the multimessenger era, allowing us to use different tracers to view the cosmos from various perspectives. Among others, the appealing application of gravitational wave events from compact binary mergers is that they can act as standard sirens to determine absolute cosmic distances entirely independent of standard candles. This approach is one of the most promising means to solve the current H0tension problem.

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Soluble epoxide hydrolase:a next-generation drug target for Alzheimer's disease and related dementias

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Neural Regeneration Research 2025年第9期20卷 2585-2586页

作者： Andrew Gregory Chengyun Tang fan fan Department of Physiology Medical College of GeorgiaAugusta UniversityAugustaGAUSA

Alzheimer's disease(AD)and Alzheimer's diseaserelated dementias(ADRD)represent a significant public health challenge,with projections indicating a substantial increase in affected individuals due to the aging global *** the World Health Organization,AD/ADRD has affected more than 55 million individuals worldwide,with an additional 10 million cases diagnosed each year.

关键词： Alzheimer population drug

Effect of a Carbon Fibre-steel Fibre-graphite Conductive Filler on the Electrothermal Properties of Cementitious Materials

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 141-151页

作者： fan Yanan WEI Hong ZHENG Hongyong DU Hongxiu Department of Architecture and Environmental Engineering Taiyuan UniversityTaiyuan 030032China College of Civil Engineering Taiyuan University of TechnologyTaiyuan 030032China

Carbon fibre,steel fibre and graphite were used as conductive fillers to prepare cementitious materials with excellent electrothermal *** electrically conductive cementitious materials with different volume dosages were analysed through compressive and flexural strength,electrochemical impedance spectroscopy and temperature rise *** equivalent circuit model was established to study the electrically conductive heat generation mechanism in the electrically conductive cementitious *** results indicate that the mechanical properties of cementitious composite materials with a ternary conductive phase are better than those of pristine cementitious materials because the fibrous filler improves their mechanical ***,the incorporation of graphite in the material reduces its *** fibrous and point-like conductive phase materials into the cementitious material enhances the overall conductive pathway and considerably reduces the electrical resistance of the cementitious material,enhancing its conductive *** volume ratios of carbon fibre,steel fibre and graphite that achieve an optimal complex doping in the cementitious material were 0.35%,0.6%and 6%,*** was determined using the mutation point of each circuit element parameter as the percolation *** addition,at a certain safety voltage,there is a uniform change between the internal and surface temperatures of the conductive cementitious material,and the heating effect in this materialis is considerably better than that in the pristine cementitious material.

关键词： cementitious composites conductive fillers electrothermal properties electrochemical impedance spectroscopy

Endoscopy-assisted lightweight diagnosis system based on transformers for colon polyp detection

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Optoelectronics Letters 2025年第1期21卷 57-64页

作者： fan Weiming YU Jiahui JU Zhaojie School of Automation and Electrical Engineering Shenyang Ligong University Department of Biomedical Engineering Zhejiang University School of Computing University of Portsmouth

The integration of endoscopy has significantly propelled the diagnosis and treatment of gastrointestinal diseases, with colonoscopy establishing itself as the primary method for early diagnosis and preventive care in colorectal cancer(CRC). Although deep learning holds promise in mitigating missed polyp rates, modern endoscopy examinations pose additional challenges, such as image blurring and atomizing. This study explores lightweight yet powerful attention mechanisms, introducing the spatial-channel transformer(SCT), an innovative approach that leverages spatial channel relationships for attention weight calculation. The method utilizes rotation operations for inter-dimensional dependencies, followed by residual transformation, encoding inter-channel and spatial information with minimal computational overhead. Extensive experiments on the CVC-Clinic DB polyp detection dataset, addressing endoscopy pitfalls, underscore the superiority of our SCT over other state-of-the-art methods. The proposed model maintains high performance, even in challenging scenarios.

关键词： Endoscopy

Macro-mechanics and Microstructure of Nanomaterial-modified Geopolymer Concrete: A Comprehensive Review

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 204-214页

作者： WANG Tao fan Xiangqian GAO Changsheng QU Chiyu The National key Laboratory of Water Disaster Prevention Nanjing Hydraulic Research InstituteNanjing 210024China Southern Marine Science and Engineering Guangdong Laboratory(Guangzhou) Guangzhou 511458China School of Water Conservancy and Transportation Zhengzhou UniversityZhengzhou 450001China

We have described in detail the effects of nano-SiO_(2),nano-CaCO_(3),carbon nanotubes,and nano-Al_(2)O_(3) on geopolymer concrete from the perspectives of macro mechanics and *** existing research results show that the mechanism of nano-materials on geopolymer concrete mainly includes the filling effect,nucleation effect,and bridging effect,the appropriate amount of nano-materials can be used as fillers to reduce the porosity of geopolymer concrete,and can also react with Ca(OH)2 to produce C-S-H gel,thereby improving the mechanical properties of geopolymer *** optimum content of nano-SiO_(2) is between 1.0%and 2.0%.The optimum content of nano-CaCO_(3) is between 2.0%and 3.0%.The optimum content of carbon nanotubes is between 0.1%and 0.2%.The optimum content of nano-Al_(2)O_(3) is between 1.0%and 2.0%.The main problems existing in the research and application of nanomaterial-modified geopolymer concrete are summarized,which lays a foundation for the further application of nanomaterial in geopolymer concrete.

关键词： nanomaterials low carbon geopolymer concrete macro-mechanics microstructure

Unmasking Social Robots’Camouflage:A GNN-Random Forest Framework for Enhanced Detection

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Computers, Materials & Continua 2025年第1期82卷 467-483页

作者： Weijian fan Chunhua Wang Xiao Han Chichen Lin School of Data Science and Intelligent Media Communication University of ChinaBeijing100024China School of Computer and Cyber Sciences Communication University of ChinaBeijing100024China Institute of Communication Studies Communication University of ChinaBeijing100024China State key Laboratory of Media Convergence and Communication Communication University of ChinaBeijing100024China

The proliferation of robot accounts on social media platforms has posed a significant negative impact,necessitating robust measures to counter network anomalies and safeguard content *** robot detection has emerged as a pivotal yet intricate task,aimed at mitigating the dissemination of misleading *** graphbased approaches have attained remarkable performance in this realm,they grapple with a fundamental limitation:the homogeneity assumption in graph convolution allows social robots to stealthily evade detection by mingling with genuine human *** unravel this challenge and thwart the camouflage tactics,this work proposed an innovative social robot detection framework based on enhanced HOmogeneity and Random Forest(HORFBot).At the core of HORFBot lies a homogeneous graph enhancement strategy,intricately woven with edge-removal techniques,tometiculously dissect the graph intomultiple revealing ***,leveraging the power of contrastive learning,the proposed methodology meticulously trains multiple graph convolutional networks,each honed to discern nuances within these tailored *** culminating stage involves the fusion of these feature-rich base classifiers,harmoniously aggregating their insights to produce a comprehensive detection *** experiments on three social robot detection datasets have shown that this method effectively improves the accuracy of social robot detection and outperforms comparative methods.

关键词： Social robot detection graph neural networks random forest homophily heterophily