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机械强度 2005年第4期27卷 403-407页

作者：黄克智吴坚黄永刚清华大学工程力学系破坏力学教育部重点实验室北京100084 清华大学

纳米力学是研究纳米尺度材料、器件与结构的力学。近年它随着纳米技术的需要而兴起并发展。文中介绍作者所参与发展的基于原子势的连续介质方法,并用于分析碳纳米管的若干力学问题。结果与分子动力学的结果进行比较。

关键词：纳米力学碳纳米管连续介质方法分子动力学纳米尺度纳米技术力学问题原子势

The LBD11-ROS feedback regulatory loop modulates vascular cambium proliferation and secondary growth in Arabidopsis

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Molecular Plant 2023年第7期16卷 1131-1145页

作者： Tuong Vi T.Dang Seungchul Lee Hyunwoo cho kyuha choi IIdoo hwang Department of Life Sciences POSTECH Biotech CenterPohang University of Science and TechnologyPohang 37673Korea Department of Industrial Plant Science&Technology College of AgricultureLife&Environmental SciencesChungbuk National UniversityCheongju 28644Korea

Vascular cambium produces the phloem and xylem,vascular tissues that transport resources and provide mechanical support,making it an ideal target for crop ***,much remains unknown about how vascular cambium *** this study,through pharmaceutical and genetic manipulation of reactive oxygen species(ROS)maxima,we demonstrate a direct link between levels of ROS and activity of LATERAL ORGAN BOUNDARIES DOMAIN 11(LBD11)in maintaining vascular cambium ***11 activates the transcriptionof several keyROS metabolic genes,including PEROXIDASE71and RESPIRATORY BURST OXIDASE HOMOLOGS D and F,to generate local ROS maxima in cambium,which in turn enhance the proliferation of cambial *** a negative feedback mechanism,higher Ros levels then repress LBD11 expression and maintain the balance of cambial cell *** findings thus reveal the role of a novel LBD11/ROS-dependent feedback regulatory system in maintaining vascular cambiumspecific redox homeostasis and radial growth inplants.

关键词： vascular cambium radial growth reactive oxygen species

Sodium-coordinated Polymeric Phthalocyanines as Stable High-capacity Organic Anodes for Sodium-Ion Batteries

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Energy & Environmental Materials 2023年第4期6卷 22-30页

作者： Jeongyeon Lee Yoonbin kim Soyong Park kang Ho Shin Gun Jang Min Jun hwang Daekyu kim kyung-Ah Min Ho Seok Park Byungchan Han Dennis k.P.Ng Lawrence Yoon Suk Lee Department of Applied Biology and chemical Technology and Research Institute for Smart Energy The Hong Kong Polytechnic UniversityHung HomKowloon Hong Kong SAR China Department of chemistry The Chinese University of Hong KongShatinNew Territories Hong Kong SAR China convergence Research center for Energy and Environmental Sciences Sungkyunkwan UniversitySuwon Korea Department of chemical and Biomolecular Engineering Yonsei UniversitySeoul Korea School of chemical Engineering Sungkyunkwan UniversitySuwon Korea

Sodium-ion batteries(SIBs)have attracted considerable interest as an alternative to lithium-ion batteries owing to their similar electrochemical performance and superior long-term cycle *** materials are regarded as promising anode materials for constructing SIBs with high capacity and good ***,utilization of organic materials is rather limited by their low energy density and poor stability at high current *** overcome these limitations,we utilized a novel polymeric disodium phthalocyanines(pNaPc)as SIB anodes to provide stable coordination sites for Na ions as well as to enhance the stability at high current *** varying the linker type during a one-pot cyclization and polymerization process,two pNaPc anodes with O-(O-pNaPc)and S-linkers(S-pNaPc)were prepared,and their structural and electrochemical properties were *** O-pNaPc binds Na ions with a lower binding energy compared with S-pNaPc,which leads to more facile Na-ion coordination/dissociation when engaged as SIB *** use of O-pNaPc significantly improves the redox kinetics and cycle stability and allows the fabrication of a full cell against Na_(3)V_(2)(PO_(4))_(2)F_(3)/c cathode,which demonstrates its practical application with high energy density(288 Wh kg^(-1))and high power density(149 W kg^(-1)).

关键词： coordination chemistry organic anode phthalocyanine polymerization sodium ion battery

Overcoming the penetration depth limit in optical microscopy:Adaptive optics and wavefront shaping

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Journal of Innovative Optical Health Sciences 2019年第4期12卷 3-20页

作者： cheolwoo Ahn Byungjae hwang kibum Nam Hyungwon Jin Taeseong Woo Jung-Hoon Park Department of Biomedical Engineering Ulsan National Institute of Science and Technology(UNIST)Ulsan South Korea

Despite the unique advantages of optical microscopy for molecular specific high resolution imaging of living structure in both space and time,curent applications are mostly limited to research *** is due to the aberrations and multiple scattering that is induced by the inhomogeneous refractive boundaries that are inherent to biological ***,recent developments in adaptive optics and wavefront shaping have shown that high resolution optical imaging is not fundamentally limited only to the observation of single cells,but can be significantly enhanced to realize deep tissue *** provide insight into how these two closely related fields can expand the limits of bio imaging,we review the recent progresses in their performance and applicable range of studies as well as potential future research directions to push the limits of deep tissuse imnaging.

关键词： Adaptive optics wavefront shaping optical aberration multiple scattering in-viuo imaging

Study of cerium-promoted rhodium alumina catalyst as a steam reforming catalyst for treatment of spent solvents

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Journal of Rare Earths 2014年第9期32卷 831-836页

作者： Hee-chul Yang Min-Woo Lee Ho-Sang hwang Jei-kwon Moon Dong-Yong chung korea Atomic Energy Research Institute

This study attempted to develop an appropriate catalyst used for the steam reforming of gasified spent solvents. Rh2O3/ ceOE-Al2O3 catalysts with various ceO2 loadings were prepared and heated at different temperatures of 500 and 800 ℃, and their surface properties were studied using X-ray diffraction （XRD）, X-ray photoelectron spectroscopy （XPS）, transmission electron microscopy （TEM）, temperature programmed reduction （TPR） and Bmmauer-Emmett-Teller （BET） analyses. Rhodium existed in the form of Rh2O3, regardless of the sample composition as well as the heating temperature. In the tested range of cerium addition （up to 12 times the rhodium mass）, no significant changes in BET surface areas and binding energy corresponding to Rh 3d5/2 were observed. Instead, the addition of cerium led to a greatly enhanced dispersion of rhodium nanoparticles, and no agglomeration of rhodium was observed for samples heated even at 800 ℃. Honeycomb monolith rhodium catalysts promoted with cerium were fabricated and tested for the steam reforming of a gasified spent solvent, mainly consisting of butylene （c4H8）. The test results suggested that a cerium-promoted rhodium catalyst could be used as an appropriate reforming catalyst for treating low-quality non-methane hydrocarbons without the formation of coke at high temperatures of up to 900 ℃.

关键词： cerium rhodium catalyst steam reforming spent resin rare earths

In silico assessment of human health risks caused by cyanotoxins from cyanobacteria

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BIOcELL 2021年第1期45卷 65-77页

作者： JIA-FONG HONG BAGHDAD OUDDANE JIANG-SHIOU hwang HANS-UWE DAHMS Department of Biomedical Science and Environmental Biology College of Life ScienceKaohsiung Medical UniversityKaohsiung807Taiwan Univ.Lille Laboratoire LASIREUMR CNRS 8516Equipe Physico-Chimie de l’EnvironnementLilleF-59000France Institute of Marine Biology Taiwan Ocean UniversityKeelung202Taiwan center of Excellence for the Oceans Taiwan Ocean UniversityKeelung202Taiwan center of Excellence for Ocean Engineering Taiwan Ocean UniversityKeelung202Taiwan Research center for Environmental Medicine KMU-Kaohsiung Medical UniversityKaohsiung807Taiwan Department of Marine Biotechnology and Resources National Sun Yat-sen UniversityKaohsiung804Taiwan

Harmful algal blooms(HABs)that are formed by cyanobacteria have become a serious issue worldwide in recent *** can release a type of secondary metabolites called cyanotoxins into aquatic systems which may indirectly or directly provide health risks to the environment and *** provide some of the most powerful natural poisons including potent neurotoxins,hepatotoxins,cytotoxins,and endotoxins that may result in environmental health risks,and long-term morbidity and mortality to animals and *** this research,we used the chemcomputational tool Molinspiration for molecular property predictions,Pred-hERG 4.2 web software for cardiac toxicity prediction,and Pred-Skin 2.0 web software for predicting skin *** are predicting some toxicological aspects of cyanobacteria here using chemcomputational tools with the hypothesis that cyanotoxins are providing a risk to human *** are using the tool Pred-hERG 4.2 to predict hERG channel blocking potential and the Pred-skin tool to predict skin sensitization due to *** potential of anatoxin,ambigol,the microcystin group,and lyngbyatoxin A,lyngbyatoxin B,nodularin-R,and saxitoxin were predicted to cause skin sensitization in the final results(consensus model).Anatoxin-a and lyngbyatoxin were predicted to allow GI absorption and blood–brain barrier *** the 20 predicted cyanotoxins only aeruginosin 103-A,ambigol A,and ambigol were predicted by Pred-hERG 4.2 according to the applicability domain results as potential cardiotoxins with weak or moderate *** shows activity through the GPcR ligand and protease,kinase,and enzyme inhibitor.

关键词： cyanotoxins Predictive model Molinspiration Bioactivity score hERG blocker carcinogenicity

Inhibition of Proliferation of Prostate cancer cell Line DU-145 in vitro and in vivo Using Salvia miltiorrhiza Bunge

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chinese Journal of Integrative Medicine 2020年第7期26卷 533-538页

作者： Woong Jin Bae Jin Bong choi kang Sup kim U Syn Ha Sung Hoo Hong Ji Youl Lee Tae-kon hwang Sung Yeoun hwang WANG Zhi-ping Sae Woong kim Department of Urology The Catholic University of KoreaCollege of MedicineSeoul(06591)Republic of Korea catholic Integrative Medicine Research Institute College of MedicineThe Catholic University of KoreaSeoul(06591)Republic of Korea korea Bio-Medical Science Institute Seoul(06106)Republic of Korea Department of Urology Second Hospital of Lanzhou UniversityLanzhou(730030)China

Objective:To investigate the antiproliferative activity of Salvia miltiorrhiza Bunge.(SM)on the castration-resistant prostate cancer(cRPc)cell line DU-145 in vitro and in ***:Prostate cancer cell line(DU-145)and normal prostate cell line(RWPE-1)were treated with SM at different concentrations(3.125,12.5,25 and 50μg/mL)to investigate the antiproliferative *** laddering analysis was performed to investigate the apoptosis of DU-145 *** mechanism was investigated by Western blot analysis of p53,Bcl-2,prostate specific antigen(PSA),and androgen receptor(AR).Six-week-old male BALB/c nude mice were randomly divided into normal control group(n=101)and treated group(n=101)which administered 500 mg/kg SM for 2 *** volumes were ***:Treatment with SM resulted in a dose-dependent decrease in cell number of DU-145 cells in comparison with *** laddering analysis indicated the apoptosis of DU-145 *** with SM increased the expression of p53 and reduced the expression of Bcl-2 *** levels of PSA were considerably reduced in SM-treated group compared to the controls,and a decrease in AR expression was observed when cells were treated with SM in the same pattern as a reduction in *** the tumour xenograft study,SM given once a day for 2 weeks significantly inhibited tumour ***:SM might contribute to the anticancer actions such as induction of apoptosis and inhibition of proliferation of prostate cancer cells.

关键词： apoptosis prostate cancer Salvia miltiorrhiza Bunge chinese medicine

Design of multi-chips LED module for lighting application

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Design of multi-chips LED module for lighting application

A case of hypermature cataract formation following implantation of an implantable collamer lens with an Aquaport

海峡两岸第九届照明科技与营销研讨会

作者： J.T.Hsu W.k.Han c.chen F.c.hwang S.P.Huang Opto-Electronics & System Laboratories Industrial Technology Research Institute chutung Hsinchu 310 Taiwan R.O.C.

White LED is well known as a promising device for solid state lighting. It has the advantages of long life, good endurance of heavy impact, no mercury containing and potentially high efficiency. However, light output from a commercial LED lamp is usually less than 0.1 W, which is very small if compared with traditional light sources. In order to get enough light output from LED devices, a big-lamp or cluster, which is packed from dozens or hundreds of LED lamps, is necessary not only for outdoor display but also for lighting applications. Some problems were encountered during high-density assembly in a big-lamp. Because of the bad heat conductivity of the epoxy, the more LED lamps are used in the big-lamp, the poorer heat dissipation will be. On the other hand, it is difficulty to manufacture a big-lamp in good alignment from each LED lamp during the package. One of the ways to solve this problem is to use a big LED chip instead of many small lamps. Nevertheless, to use those big chips always companions 10-25% loss in the external quantum efficiency. And, the bigger the chip is, the larger the loss will be. Highly concentrated heat will be another issue for the big chip package.

关键词： GaN LED lighting package

来源： cnki会议评论

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International Journal of Ophthalmology(English edition) 2017年第6期10卷 1014-1015页

作者： kyu-Yeon hwang Sung A.Lim So-Hyang chung Department of Ophthalmology Konyang University Kim＇s Eye Hospital Seoul 07301 Korea Nune Eye Hospital Daegu 42019 Korea Department of Ophthalmology and visual science Seoul St. Mary＇s Hospital College of Medicine the Catholic University of Korea Seoul 06591 Korea

To improve humor circulation the latest V4c Visian implantable collamer lens （IcL） was designed with a0.36-ram Aquapon. This design also eliminates the need to perform peripheral iridectomy before IcL implantation. Several authors reported rates of secondary surgical intervention related to insufficient vault in the presence or absence of cataract formation and excessive vault in the presence or absence of elevated intraocular pressure （IOP） after IcL insertion. Here, we report a case of rapid progression of a cataract to a hypermature state after implantation of an IcL with an Aquaport.

关键词： IcL A case of hypermature cataract formation following implantation of an implantable collamer lens with an Aquaport case

Optimistic performance of carbon-free hydrazine fuel cells based on controlled electrode structure and water management

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Journal of Energy chemistry 2020年第12期29卷 175-181页

作者： Hongsun hwang Sujik Hong Do-Hyeong kim Moon-Sung kang Jin-Soo Park Sunghyun Uhm Jaeyoung Lee Electrochemical Reaction and Technology Laboratory(ERTL) School of Earth Sciences and Environmental EngineeringGwangju Institute of Science and Technology(GIST)Cwangju 61005Republic of Korea Ertl center for Electrochemistry and catalysis Gwangju Institute of Science and Technology(GIST)Gwangju 61005Republic of Korea Department of Green chemical Engineering Sangmyung UniversityCheonanChungnam 31066Republic of Korea Plant Engineering center Institute for Advanced EngineeringYongin 17180Republic of Korea

In this study, we first attempted to discover the optimal configuration of membrane-electrode assemblies(MEAs) used to achieve a high performance of direct hydrazine fuel cells(DHFcs). We have investigated the effect of water management and the electrode thickness on the performance of DHFcs, depending on the hydrophobicity of the gas diffusion layers in the cathode and the catalyst loading in the anode with the carbon-supported Ni, synthesized by a polyol process. With the optimal water management and electrode thickness, the MEA constructed using the as-prepared Ni/c anode catalyst containing the metallic and low oxidative state and ultra-low Pt loading cathode reduced the ohmic resistance and mass transfer limitation in the current-voltage curves observed for the alkaline DHFc, achieving an impressive power performance over 500 mW cm^(–2).

关键词： Fuel cell Hydrazine Alkaline media Membrane-electrode assembly