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Green tea extract as a cryoprotectant additive to preserve the motility and DNA integrity of human spermatozoa

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Asian Journal of Andrology 2021年第2期23卷 150-156页

作者： Odai AM Alqawasmeh Mingpeng Zhao carol PS chan Maran BW Leung ki c chow Nikunj Agarwal Jennifer SM Mak chi c Wang chi P Pang Tin c Li Wai k chu David YL chan Assisted Reproductive Technology Unit Department of Obstetrics and GynaecologyFaculty of MedicineThe Chinese University of Hong KongHong KongChina Department of Ophthalmology and Visual Sciences The Chinese University of Hong KongHong KongChina

cryopreservation impairs sperm quality and functions,including motility and DNA *** additives in sperm freezing media have previously brought improvements in postthawed sperm *** tea extract(GTE)is widely considered as an excellent antioxidant,and its beneficial role has been proven in other human *** study aims to evaluate the GTE as a potential additive in cryopreservation media of human *** part one,the semen of 20 normozoospermic men was used to optimize the concentration of GTE that maintains sperm motility and DNA integrity against oxidative stress,induced by hydrogen peroxide(H_(2)O_(2)).Spermatozoa were treated with GTE at different concentrations before incubation with H_(2)O_(2).In part two,the semen of 45 patients was cryopreserved with or without 1.0 ng ml^(-1)*** 2 weeks,the semen was thawed,and the effect on sperm motility and DNA fragmentation was *** data showed that GTE significantly protected sperm motility and DNA integrity against oxidative stress induced by H_(2)O_(2)when added at a final concentration of 1.0 ng ml^(-1).We found that the addition of 1.0 ng ml^(-1)GTE to cryopreservation media significantly increased sperm motility and DNA integrity(both Pcant change in the reactive oxygen species(ROS)*** conclusion,supplementing sperm freezing media with GTE has a significant protective effect on human sperm motility and DNA integrity,which may be of clinical interest.

关键词： antioxidants cryopreservation additives sperm cryopreservation sperm DNA fragmentation sperm motility

comprehensive characterization of indoor airborne bacterial profile

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Journal of Environmental Sciences 2009年第8期21卷 1148-1152页

作者： P. L. chan P. H. F. Yu Y. W. cheng c. Y. chan P. k. Wong Department of Biology The Chinese University of Hong Kong Department of Applied Biology and chemical Technology The Hong Kong Polytechnic University Department of Microbiology The Chinese University of Hong Kong

This is the first detailed characterization of the airborne bacterial profiles in indoor environments. Two restaurants were selected for this study. Fifteen genera of bacteria were isolated from each restaurant and identified by three different bacterial identification systems including MIDI, Biolog and Riboprinter. The dominant bacteria of both restaurants were Gram-positive bacteria in which Micrococcus and Bacillus species were the most abundant. Most bacteria identified were representative species of skin and respiratory tract of human, and soil. Although the bacterial levels in these two restaurants were below the limit of the Hong kong Indoor Air Quality Objective （HkIAQO） Level 1 standard （i.e., 〈 500 cfu/m^3）, the majority of these bacteria were opportunistic pathogens. These results suggested that the identity of airborne bacteria should also be included in the IAQ to ensure there is a safety guideline for the public.

关键词： airborne bacterial profile bacterial identification indoor air quality

Automotive revolution and carbon neutrality

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Frontiers in Energy 2023年第6期17卷 693-703页

作者： c.c.chan Wei HAN Hanlei TIAN Yanbing LIU Tianlu MA c.Q.JIANG Department of Electrical and Electronic Engineering The University of Hong KongHong KongChina Sustainable Energy and Environment Thrust Hong Kong University of Science and Technology(Guangzhou)Guangzhou 511453China Department of Electronic and computer Engineering Hong Kong University of Science and TechnologyHong KongChina Department of Electrical Engineering City University of Hong KongHong KongChina HkUST Shenzhen-Hong kong collaborative Innovation Research Institute Shenzhen 518048China

The automotive industry is in the midst of a groundbreaking revolution,driven by the imperative to achieve intelligent driving and carbon neutrality.A crucial aspect of this transformation is the transition to electric vehicles(EVs),which necessitates widespread changes throughout the entire automotive *** paper examines the challenges and opportunities of this transition,including automotive electrification,intelligence-connected transportation system,and the potential for new technologies such as hydrogen fuel ***,it discusses the key technologies and progress of the hydrogen energy industry chain in the upstream hydrogen production,midstream hydrogen storage and transportation,downstream hydrogen station construction and hydrogen fuel cells in ***,it proposes the directions for future layout,providing guidance for future development.

关键词： automotive revolution electric vehicles(EVs) hydrogen energy fuel cell

Nonlinear Pulse compression and Reshaping Using cross-Phase Modulation in a Dispersion-Shifted Fiber

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光学学报 2003年第S1期23卷 395-396页

作者： S. W. chan k. k. chow c. Shu The chinese University of Hong kong Department of Electronic Engineering Shatin N.T. Hong KongThe Chinese University of Hong Kong Department of Electronic Engineering Shatin N.T. Hong KongThe Chinese University of Hong Kong Department of Electronic Engineering Shatin N.T. Hong Kong

Nonlinear pulse compression has been demonstrated by cross-phase modulation in a dispersion-shifted fiber. The output is obtained from filtering of the broadened optical spectrum and a pulse width reduction from 61 to... 详细信息

关键词： DSF of line on IEEE as in Nonlinear Pulse compression and Reshaping Using cross-Phase Modulation in a Dispersion-Shifted Fiber EDFA XPM dBm

Ultra‑Transparent and Multifunctional IZVO Mesh Electrodes for Next‑Generation Flexible Optoelectronics

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Nano-Micro Letters 2025年第1期17卷 293-309页

作者： kiran A.Nirmal Tukaram D.Dongale Atul c.khot chenjie Yao Nahyun kim Tae Geun kim School of Electrical Engineering Korea UniversityAnam‑ro 145Seongbuk‑guSeoulRepublic of Korea computational Electronics and Nanoscience Research Laboratory School of Nanoscience and BiotechnologyShivaji UniversityKolhapur 416004India

Mechanically durable transparent electrodes are essential for achieving long-term stability in flexible optoelectronic ***,they are crucial for applications in the fields of energy,display,healthcare,and soft *** meshes represent a promising alternative to traditional,brittle,metal oxide conductors due to their high electrical conductivity,optical transparency,and enhanced mechanical *** this paper,we present a simple method for fabricating an ultra-transparent conducting metal oxide mesh electrode using selfcracking-assisted *** this method,we produced an electrode with ultra-transparency(97.39%),high conductance(Rs=21.24Ωsq^(−1)),elevated work function(5.16 eV),and good mechanical *** also evaluated the effectiveness of the fabricated electrodes by integrating them into organic photovoltaics,organic light-emitting diodes,and flexible transparent memristor devices for neuromorphic computing,resulting in exceptional device *** addition,the unique porous structure of the vanadium-doped indium zinc oxide mesh electrodes provided excellent flexibility,rendering them a promising option for application in flexible optoelectronics.

关键词： Self-cracking template Vanadium-doped indium zinc oxide mesh Organic solar cells Organic light-emitting diodes Flexible transparent memory

Network coding-aware cache replacement policy in on-demand broadcast environments

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Journal of Harbin Institute of Technology(New Series) 2012年第5期19卷 92-100页

作者：陈君 LEE Victor c S chan Edward School of Information Management Wuhan UniversityWuhan 430072China Dept.of computer Science City University of Hong KongHong KongChina

Network coding has been proved to be an effective technique in improving the performance of data broadcast systems because clients requesting different data items can be served simultaneously in one broadcast. Previous studies showed that its efficiency is highly related to the content of clients' cache. However, existing data broadcast systems do not take network coding information into account when making cache replacement decisions. In this paper, we propose two networks coding-aware cache replacement policies called DLRU and DLRU-cP to supplement network coding assisted data broadcast in on-demand broadcast environments. In DLRU, both data access and decoding contribution are taken into account to make replacement decisions. DLRU-cP is based on DLRU but allows clients to retrieve decodable data items that have not been requested yet. The performance gain of our proposed cache replacement policies over traditional cache replacement policy is shown in the simulation results, which demonstrate conclusively that the proposed policies can effectively reduce the overall response time.

关键词： Network coding cache replacement on-demand broadcast mobile computing

Role of c11-FDG dual-tracer PET-cT scan in metastatic screening of hepatocellular carcinoma-a cost-effectiveness analysis

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Hepatobiliary Surgery and Nutrition 2021年第3期10卷 301-307页

作者： kevin k.W.chu Albert c.Y.chan ka Wing Ma Wong Hoi She Wing chiu Dai kenneth S.H.chok Tan To cheung chung Mau Lo Department of Surgery The University of Hong KongHong KongChina

Background:We aimed to identify predictive factors for positron emission tomography(PET)-detected hepatocellular carcinoma(Hcc)metastasis and a cost-effective approach to preoperative PET-computed tomography(cT)for detecting ***:clinicopathological and survival data of Hcc patients having PET-cT with 18F-fludeoxyglucose(FDG)and 11c-acetate(AcT)following contrast-enhanced cT/magnetic resonance imaging(MRI)for preoperative tumor staging were *** logistic regression was performed to identify predictive factors for PET-detected metastasis.A cost-benefit analysis model was built for the incurred costs and the impact of PET-cT findings on treatment strategy was ***:Totally 152 patients were ***-tracer PET-cT detected metastasis in 17 patients(11%).By multivariate analysis,alpha-fetoprotein(AFP)≥400 ng/mL[relative risk(RR):4.30,95%confidence interval(cI):1.41-13.15,P=0.011]and bilobar disease(RR:3.94,95%cI:1.24-12.52,P=0.014)were independent predictive factors for PET-detected ***-cT findings altered the treatment strategy for 12 patients(7.9%);three partial hepatectomies,eight episodes of transarterial chemoembolization(TAcE)and one episode of ablation were avoided,with an estimated cost-saving of US$91,000,$150,000 and$10,600 *** the PET-cT been performed only for patients with AFP≥400 ng/mL or bilobar disease(n=74),metastasis would have been confirmed in 14 patients(18.9%),and the cost-saving per patient was estimated at US$1,***:Dual-tracer PET-cT is cost-effective and useful for preoperative Hcc staging in patients with AFP≥400 ng/mL or bilobar *** routine use in preoperative workup for all Hcc patients is not *** disease with AFPcan achieve good negative predictive value for PET-detected *** patients with either factor can avoid unnecessary procedures and is thus cost-effective for preoperative Hcc workup.

关键词： cost-effectiveness study dual-tracer positron emission tomography-computed tomography(dual-tracer PET-cT) hepatocellular carcinoma(Hcc) metastatic screening preoperative investigation

A patient with relapsed high-grade serous ovarian carcinoma with somatic RAD51c mutations treated with PARPi monotherapy:a case report

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cancer Drug Resistance 2022年第3期5卷 662-666页

作者： Siew-Fei Ngu Hextan Y.S.Ngan karen k.L.chan Department of Obstetrics and Gynaecology The University of Hong KongHong KongChina

We report our experience in the management of a relapsed ovarian cancer patient with somatic RAD51c mutation,treated with olaparib *** patient was diagnosed with stage 4 high-grade serous ovarian carcinoma and was treated with neoadjuvant chemotherapy,cytoreductive surgery,and postoperative *** a second cancer recurrence,she underwent FoundationOne cDx testing following disease progression on multiple lines of *** on the FoundationOne cDx results,olaparib monotherapy was *** 13 months of therapy,all lesions responded to the treatment,and she achieved complete response as demonstrated by normalization of the levels of cA125 and positron emission tomography-computed tomography(PET-cT).We plan to continue olaparib monotherapy until disease progression.

关键词： Ovarian cancer PARP inhibitor BRcA RAD51c

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基于二阶矩燃烧模型的液雾燃烧大涡模拟

工程热物理学报 2012年第3期33卷 521-524页

作者：李科周力行 chan c k 清华大学航天航空学院北京100084 内蒙古科技大学内蒙古包头014010 Department of Applied Mathematics The Hong Kong Polytechnic University

采用亚网格动能(k方程)应力模型、二阶矩(SOM)燃烧模型和欧拉拉氏两相流模型,对乙醇-空气液雾燃烧进行了大涡模拟(LES)。瞬态结果显示:在火焰的高温区域,旋涡强度较大;在高温区边缘附近存在的拟序结构有脱落的趋势。在燃烧装置的燃料进... 详细信息

采用亚网格动能(k方程)应力模型、二阶矩(SOM)燃烧模型和欧拉拉氏两相流模型,对乙醇-空气液雾燃烧进行了大涡模拟(LES)。瞬态结果显示:在火焰的高温区域,旋涡强度较大;在高温区边缘附近存在的拟序结构有脱落的趋势。在燃烧装置的燃料进口附近,近喷嘴中心区域,大量液滴聚集在条状湍流拟序结构的周围。LES模拟的统计结果给出的温度分布与实验结果吻合较好。说明SOM燃烧模型适用于液雾两相湍流燃烧研究,计算结果经过和实验数据对比发现,LES-SOM燃烧模型优于RANS-PDF及LES-FA计算结果。数值计算结果与实验结果的误差主要是由于采用统观一步反应机理引起的,表明燃烧模型还有待进一步改进。

关键词：二阶矩燃烧模型液雾燃烧大涡模拟