检索结果-南通市图书馆

Binding interaction of phosphorus heterocycles with bovine serum albumin:A biochemical study

Journal of Pharmaceutical Analysis 2017年第1期7卷 19-26页

作者： Swarup Roy Raj kumar Nandi Sintu Ganai k.c. majumdar Tapan k. Das Department of Biochemistry and Biophysics University of Kalyani Kalyani 741235 West Bengal India Department of chemistry University of Kalyani Kalyani 741235 West Bengal India

Interaction between bovine serum albumin(BSA) and phosphorus heterocycles(PHs) was studied using multispectroscopic techniques. The results indicated the high binding affinity of PHs to BSA as it quenches the intrinsic fluorescence of BSA. The experimental data suggested the fluorescence quenching mechanism between PHs and BSA as a dynamic quenching. From the UV–vis studies, the apparent association constant(k_(app)) was found to be 9.25×10~2, 1.27×10~4and 9.01×10~2L/mol for the interaction of BSA with PH-1, PH-2 and PH-3,respectively. According to the F?rster's non-radiation energy transfer(FRET) theory, the binding distances between BSA and PHs were calculated. The binding distances(r) of PH-1, PH-2 and PH-3 were found to be2.86, 3.03, and 5.12 nm, respectively, indicating energy transfer occurs between BSA and PHs. The binding constants of the PHs obtained from the fluorescence quenching data were found to be decreased with increase of temperature. The negative values of the thermodynamic parameters ΔH, ΔS and ΔG at different temperatures revealed that the binding process is spontaneous; hydrogen bonds and van der Waals interaction were the main force to stabilize the complex. The microenvironment of the protein-binding site was studied by synchronous fluorescence and circular dichroism(cD) techniques and data indicated that the conformation of BSA changed in the presence of PHs. Finally, we studied the BSA-PHs docking using Auto Dock and results suggest that PHs is located in the cleft between the domains of BSA.

关键词： BSA Spectroscopy Phosphorus heterocycles BSA-PHs docking

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Observation of~100%valley-coherent excitons in monolayer MoS_(2) through giant enhancement of valley coherence time

引用

Light(Science & Applications) 2023年第8期12卷 1644-1650页

作者： Garima Gupta kenji Watanabe Takashi Taniguchi kausik majumdar Department of Electrical communication Engineering Indian Institute of ScienceBangaloreIndia Research center for Functional Materials National Institute for Materials ScienceTsukubaJapan international center for Materials Nanoarchitectonics National Institute for Materials ScienceTsukubaJapan

In monolayer transition metal dichalcogenide semiconductors,valley coherence degrades rapidly due to a combination of fast scattering and inter-valley exchange *** leads to a sub-picosecond valley coherence time,making coherent manipulation of exciton a highly challenging task Using monolayer MoS_(2) sandwiched between top and bottom graphene,here we demonstrate fully valley-coherent excitons by observing~100%degree of linear polarization in steady state *** is achieved in this unique design through a combined effect of(a)suppression in exchange interaction due to enhanced dielectric screening,(b)reduction in exciton lifetime due to a fast inter-layer transfer to graphene,and(c)operating in the motional narrowing *** disentangle the role of the key parameters affecting valley coherence by using a combination of calculation(solutions of Bethe-Salpeter and Maiallle-Silva-Sham equations)and a careful choice of design of experiments using four different stacks with systematic variation of screening and exciton *** the best of our knowledge,this is the first report in which the excitons are found to be valley coherent in the entire lifetime in monolayer semiconductors,allowing optical readout of valley coherence possible.

关键词： coherent monolayer lifetime

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Oilfield geothermal resources of the Upper Assam Petroliferous Basin,NE India

引用

Energy Geoscience 2021年第4期2卷 246-253页

作者： Dilip majumdar Abhilekha Devi Department of Applied Geology Dibrugarh UniversityAssam786004India

Extracting geothermal energy from the oil-producing fields is an experimental venture *** exploitation and utilization of geothermal energy can partly reduce the larger dependence on conventional non-renewable energy sources like oil,gas,coal,and other fossil fuels,and has a bright *** Upper Assam Basin is a mature petroliferous basin of NE India,where there are several hundred low production,high water cut,or abandoned oil and gas wells that can be retrofitted as geothermal wells instead of drilling new *** will help bridge the gap of growing energy demand and limited supply in energy-deficient state like *** away from the active plate boundaries and in lack of active volcanism,the Upper Assam Basin remains a low-to-medium enthalpy geothermal fluid *** deeper reservoir in this regard can,therefore,be the best candidate for the introspection of the potential geothermal energy reservoir *** selection of a deeper horizon considered in the present case has been the stratified reservoirs of the Lakadong-Therria(Lk-Th)Formation,Sylhet Group of the Lower Eocene age occurring at a variable depth of 3400 me 4600 *** Lk-Th Formation possesses a fair-quality reservoir with lateral continuity and favourable petrophysical *** this study,representative gamma-ray(GR)and resistivity(R)logs were examined to work out lithology,and bed boundary demarcation,*** total Formation thickness varies from 97 to 157 m;the individual sand body thickness is up to 6 *** reservoir parameters,e.g.,porosity(φ=8-33%),water saturation(S_(w)=4.57-95.15%),geothermal gradient(2.71℃/100m to 3.92 c/100 m at 4300 m and 3608 m)respectively,and theoretical estimate of high heat flux in the range 70e100 mW/m^(2)/s,are the necessary yard-stick to measure the subsurface geothermal *** energy extraction will have the potential in facilitating energy utilization for industrial purposes,especially in tea processing units pr

关键词： Upper Assam Petroliferous Basin Geothermal energy Water cut Abandoned oil/gas well Geothermal gradient

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Soldiers' load carriage performance in high mountains: a physiological study

引用

Military Medical Research 2017年第3期4卷 132-140页

作者： Tirthankar chatterjee Debojyoti Bhattacharyya Anilendu Pramanik Madhusudan Pal Deepti majumdar Dhurjati majumdar Defence Institute of Physiology and Allied Sciences Defence Research & Development Organisation Ministry of DefenceGovernment of India Retired from-Institute of Nuclear Medicine and Allied Sciences Defence Research and Development Organization Ministry of DefenceGovernment of India

Background: The present study was designed to evaluate load carriage performance at extremely high altitudes with different loads and walking speeds in terms of physiological evaluation. The degree of maximum oxygen consumption changes at high altitudes was also ***: Twelve Indian Army soldiers were acclimatized at altitudes of 3,505 m and 4,300 m. They walked for 10 minutes on a motorized treadmill at 2.5km/h and 3.5km/h speeds during carrying no loads and three magnitudes of load(10.7kg, 21.4kg, 30kg) at both altitudes. Physiological parameters such as oxygen consumption, energy expenditure, heart rate, and ventilation were recorded for each breath using a gas analyzer. The rating of perceived exertion was also noted after each load carriage session. Maximal oxygen consumption(VO2max) was measured at sea level and the two high altitudes, and respective relative workloads(% of VO2max) were calculated from oxygen consumption. Repeated measure ANOVA was applied to reveal the significant effects of the independent ***: The participants had significant reductions in VO2 max with rising altitude. Marked increases in almost all physiological parameters were observed with increasing load, altitude, and speed. The soldiers expressed heavy perceived exertion levels with higher loads at 3.5km/h at the two high ***: considering the physiological responses, expressions of perceived exertion and changes in relative work load at both of the high altitudes. Indian soldiers are advised to walk slowly with adequate rest in between their schedules and to carry not more than 32% of their body weight.

关键词： Load carriage High altitude Walking speed Physiological responses

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

calculation of Available Transfer capability Using Hybrid chaotic Selfish Herd Optimizer and 24 Hours RES-thermal Scheduling

引用

chinese Journal of Electrical Engineering 2023年第4期9卷 54-72页

作者： kingsuk majumdar Provas kumar Roy Subrata Banerjee Department of Electrical Engineering Dr.B C Roy Engineering CollegeDurgapur 713206India Department of Electrical Engineering Kalyani Government Engineering CollegeKalyani 741235India Department of Electrical Engineering NIT DurgapurDurgapur 713209India

As fossil fuel stocks are being depleted,alternative sources of energy must be ***,traditional thermal power plants must coexist with renewable resources,such as wind,solar,and hydro units,and all-day planning and operation techniques are necessary to safeguard nature while meeting the current *** fundamental components of contemporary power systems are the simultaneous decrease in generation costs and increase in the available transfer capacity(ATc)of current *** units are linked to sources of renewable energy such as hydro,wind,and solar power,and are set up to run for 24 *** contrast,new research reports that various chaotic maps are merged with various existing optimization methodologies to obtain better results than those without the inclusion of *** seems to increase the performance and convergence properties of existing optimization *** this study,selfish animal tendencies,mathematically represented as selfish herd optimizers,were hybridized with chaotic phenomena and used to improve ATc and/or reduce generation costs,creating a multi-objective optimization *** evaluate the performance of the proposed hybridized optimization technique,an optimal power flow-based ATc was enforced under various hydro-thermal-solar-wind conditions,that is,the renewable energy source-thermal scheduling concept,on IEEE 9-bus,IEEE 39-bus,and Indian Northern Region Power Grid 246-bus test *** findings show that the proposed technique outperforms existing well-established optimization strategies.

关键词： Available transfer capability(ATc) biogeography-based optimization(BBO) chaotic map chaotic selfish herd optimizer(cSHO) grey wolf optimizer(GWO) optimum power flow(OPF) power generation cost(PGc) renewable energy sources(RES) selfish herd optimizer(SHO)

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

L-Plastin deficiency produces increased trabecular bone due to attenuation of sealing ring formation and osteoclast dysfunction

引用

Bone Research 2020年第1期8卷 53-62页

作者： Meenakshi Achellaiah Megan cMoorer Sunipa majumdar Hanan Aljohani Sharon cMorley Vanessa Yingling Joseph PStains Department of Oncology and Diagnostic Sciences School of DentistryUniversity of MarylandBaltimoreMDUSA Department of Orthopedics University of Maryland School of MedicineBaltimoreMDUSA Department of Pediatrics Division of Infectious Diseasesand Department of Pathology and ImmunologyWashington University School of MedicineSt.LouisMOUSA Department of kinesiology California State UniversityEast BayHaywardCAUSA

Bone resorption requires the formation of complex, actin-rich cytoskeletal structures. During the early phase of sealing ring formation by osteoclasts, L-plastin regulates actin-bundling to form the nascent sealing zones(NSZ). Here, we show that L-plastin knockout mice produce osteoclasts that are deficient in the formation of NSZs, are hyporesorptive, and make superficial resorption pits in vitro. Transduction of TAT-fused full-length L-plastin peptide into osteoclasts from L-plastin knockout mice rescued the formation of nascent sealing zones and sealing rings in a time-dependent manner. This response was not observed with mutated full-length L-plastin(Ser-5 and-7 to Ala-5 and-7) peptide. In contrast to the observed defect in the NSZ, L-plastin deficiency did not affect podosome formation or adhesion of osteoclasts in vitro or in vivo. Histomorphometry analyses in 8-and 12-week-old female L-plastin knockout mice demonstrated a decrease in eroded perimeters and an increase in trabecular bone density, without a change in bone formation by osteoblasts. This decrease in eroded perimeters supports that osteoclast function is attenuated in L-plastin knockouts. Micro-cT analyses confirmed a marked increase in trabecular bone mass. In conclusion, female L-plastin knockout mice had increased trabecular bone density due to impaired bone resorption by osteoclasts. L-plastin could be a potential target for therapeutic interventions to treat trabecular bone loss.

关键词： sealing impaired fused

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

changes of woody species diversity, horizontal and vertical distribution of stems across interior to outside within a primate rich habitat of Northeast India

引用

Journal of Forestry Research 2016年第4期27卷 787-798页

作者： koushik majumdar Bal krishan choudhary Badal kumar Datta Plant Taxonomy and Biodiversity Lab. Department of Botany Tripura University

The interior forest of protected area（PA）recover quickly in terms of greater diversity and structural complexity than peripheral and outsides, which may be due to high plant-frugivore interactions in the interior forest than the disturbed outsides. To describe the structural and functional differences in tree communities from interior to outside forests with in small PA, we quantitatively analyzed the vegetation of Trishna Wildlife Sanctuary, a rich primate habitat of Northeast India. Vegetation was sampled at c10 cm girth at breast height by 10 m 9 500 m sized20 line transects（10 ha） laid in the interior（N = 7）,peripheral（N = 7） and outside（N = 6） zones of this sanctuary. All transects were ordinated by Principal component Analysis based on correlation between diversity and existing disturbance indices. We found significant differences（P ／ 0.05） in taxonomic richness and diversity indices between the habitat. Van diagram confirmed greater unique species richness in the interior zone（64） than peripheral（28） and outside（6） zones. Overall density（ha-1） did not differed across the zones, but basal area（m2ha-1） was significantly（P ／ 0.01） high in peripheral zone. Vertical distribution of stem density was linearly declined across zones（r2adj[ 0.70; P ／ 0.01） with increase in the canopy height. Horizontal distribution of adult stems showed significant inverse quadratic relationship（r2adj[ 0.80; P ／ 0.001）, which suggests very low density of canopy forming voluminous trees in the interior *** protection, restoration and management of interior regions are required to preserve local plant genetic diversity and also to maintain suitable habitat for threatened wildlife.

关键词： interior outside habitat restoration Northeast disturbance quickly inverse preserve quadratic

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Antimicrobial activity of cannabis sativa,Thuja orientalis and Psidium guajava leaf extracts against methicillin-resistant Staphylococcus aureus

引用

Journal of Integrative Medicine 2018年第5期16卷 350-357页

作者： Shohini chakraborty Nashra Afaq Neelam Singh Sukanta majumdar Department of Microbiology Saaii College of Medical Science and Technology Microbiology and Microbial Biotechnology Laboratory Department of BotanyUniversity of Gour Banga

Objective： This study examined the antimicrobial activity of cannabis sativa, Thuja orientalis and Psidium guajava against methicillin-resistant Staphylococcus aureus （MRSA） and used a standardized purification protocol to determine the presence and abundance of bioactive compounds in the leaf extracts. Methods： In vitro antimicrobial activities of the ethanolic extracts of c sativa, T. orientalis and P. guajava were tested against MRSA. The presence of bioactive molecules in these three leaves was evaluated using biochemical assays and high-performance thin-layer chromatography （HPTLc）. Results： Resistance to methicillin, penicillin, oxacillin and cefoxitin was observed in each of the clinical and nonclinical MRSA isolates. However, they were still vulnerable to vancomydn. Used individually, the 50% extract of each plant leaf inhibited MRSA growth. A profound synergism was observed when c sativa was used in combination with T. orientalis （1：1 ） and when P. guajava was used in combination with T. orientalis （1：1 ）. This was shown by larger zones of inhibition. This synergism was probably due to the combined inhibitory effect of phenolics present in the leaf extracts （i.e., quercetin and gallic acid） and catechin, as detected by HPTLc. conclusion： The leaf extracts of c sativa, T. orientalis and P. guajava had potential for the control of both hospital- and community-acquired MRSA. Moreover, the inhibitory effect was enhanced when extracts were used in combination.

关键词： Methicillin-resistant Staphy lococcus aureus Antimicrobial activity Plant extracts Synergistic effect High-performance thin-layer chromatography

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

TANGENT UNIT-VEcTOR FIELDS:NONABELIAN HOMOTOPY INVARIANTS AND THE DIRIcHLET ENERGY

引用

Acta Mathematica Scientia 2010年第5期30卷 1357-1399页

作者： A.majumdar J.M.Robbins M.Zyskin Mathematical Institute University of Oxford24-29 St.GilesOxford OX1 3LBUK School of Mathematics University of BristolUniversity WalkBristol BS8 1TWUK Department of Mathematics SETB 2.454-80 Fort BrownBrownsvilleTX 78520USA

Let O be a closed geodesic polygon in S2. Maps from O into S2 are said to satisfy tangent boundary conditions if the edges of O are mapped into the geodesics which contain them. Taking O to be an octant of S2, we compute the infimum Dirichlet energy 6（H） for continuous maps satisfying tangent boundary conditions of arbitrary homotopy type H. The expression for c（H） involves a topological invariant - the spelling length - associated with the （non-abelian） fundamental group of the n-times punctured two-sphere, π1（S2 - {s1,..., sn}, ＊）. The lower bound for c（H） is obtained from combinatorial group theory arguments, while the upper bound is obtained by constructing explicit representatives which, on all but an arbitrarily small subset of O, are alternatively locally conformal or anticonformal. For conformal and anticonformal classes （classes containing wholly conformal and anticonformal representatives respectively）, the expression for c（H） reduces to a previous result involving the degrees of a set of regular values sl,…… sn in the target 82 space. These degrees may be viewed as invariants associated with the abelianization of vr1（S2 - {s1,..., sn}, ＊）. For nonconformal classes, however, ε（H） may be strictly greater than the abelian bound. This stems from the fact that, for nonconformal maps, the number of preimages of certain regular values may necessarily be strictly greater than the absolute value of their degrees. This work is motivated by the theoretical modelling of nematic liquid crystals in confined polyhedral geometries. The results imply new lower and upper bounds for the Dirichlet energy （one-constant Oseen-Frank energy） of reflection-symmetric tangent unitvector fields in a rectangular prism.

关键词： harmonic maps conformal maps algebraic topology non-abelian homotopy invariants eombinatorics liquid crystals

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Monitoring Training Load,Muscle Damage,and Body composition changes of Elite Indian Rowers During a Periodized Training Program

引用

Journal of Science in Sport and Exercise 2023年第4期5卷 348-359页

作者： Arnab Das Usha S.kaniganti Shruti J.Shenoy Pralay majumdar Alak k.Syamal Department of Sports Science and Yoga Ramakrishna Mission Vivekananda Educational and Research InstituteBelurWest BengalIndia Department of Sports Science Sports Authority of IndiaBengaluruKarnatakaIndia Department of Exercise and Sports Science Manipal College of Health ProfessionsManipal Academy of Higher EducationManipalKarnatakaIndia Department of Physiology Hooghly Mohsin CollegeThe University of BurdwanBurdwanWest BengalIndia

Purpose The purpose of this study was to monitor the Indian national rowing team’s training regime and the changes that occur in the rowers’body composition,muscle cell damage,and training load markers during the phases of preparation for an international *** Ten male and 9 female elite rowers from the national team underwent anthropometric assessment and blood tests during 17 weeks of training,at the end of general preparation(W4),preparation(W10),and pre-competition(W17)*** fat%and somatotype were determined by Siri’s equation and Heath-carter manual,*** of blood biomarkers included measures of creatine phosphokinase(cPk),lactate dehydrogenase(LDH),urea,uric acid,testosterone,and cortisol *** changes in variables were estimated by repeated-measures *** fat%(Pcreased significantly at pre-competition,whereas weight,mesomorph,and ectomorph remained unchanged throughout ***(male:d=−1.47;female:d=−1.46)and uric acid(male:d=−0.74;female:d=−1.71)showed a significant decrease at pre-competition phase in both *** concentration significantly(Pcreased at preparation(d=−1.05)and increased during pre-competition(d=−1.28)in male *** showed significant increase(Pcompetition(male:d=1.28;female:d=2.09)than base ***,no significant changes were observed in cortisol,testosterone,or T/c ratio in subsequent *** correlation(Pc ratio with rowing timing in male *** 2000 m rowing timing also showed a significant improvement at W17 compared to W4(male:d=−1.25;female:d=−0.94).conclusion In conclusion,our results showed that rowers encounter more muscle damage and less protein catabolism during training ***,it is evidenced that rowing performance improved and bio

关键词： Periodization creatine phosphokinase Lactate dehydrogenase Testosterone Body fat percentage Rowing

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：