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Chinese Chemical Letter. 2024年第8期35卷 93-100页

作者： Aolei Tan Xiaoxiao ma Depar.ment of Pr.cision Instr.ment Tsinghua UniversityBeijing 100084China

Metabolism encompasses a ser.es of intr.cate biochemical pr.cesses that ar. vital for.the sustenance of life in ***,an essential scientific discipline,is a field of study within the br.ader.domain of systems biology that focuses on the compr.hensive analysis of small molecules,k.own as metabolites including lipids,coenzymes,etc.,which ar. synthesized dur.ng *** the contin-uous development of metabolomics,the multiple biological functions of metabolites ar. constantly being discover.d,encompassing signal tr.nsduction and enzyme stimulation,while concur.ently exhibiting as-sociations with afflictions lik. cancer.and *** compr.hension of metabolite functionalities and their.intr.cate inter.lay with disease conditions assumes par.mount impor.ance in both disease-focused r.sear.h endeavor. and the development of diagnostic *** scholar.y exposition under.ak.s an ex-tensive r.view of r.cent advancements in the investigation of functional r.les assumed by metabolites,with specific emphasis on metabolites in lipid synthesis,glucose metabolism and exogenous metabolites.

关键词： Metabolites Small molecules Biological functions Physiological pr.cesses Diseases

Covalent Bond Based Andr.id malwar. Detection Using Per.ission and System Call Pair.

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Computer., mater.als & Continua 2024年第3期78卷 4283-4301页

作者： r.hul Gupta k.pil Shar.a r.k.Gar. Depar.ment of Infor.ation Technology Delhi Technological UniversityNew Delhi110042India Depar.ment of Mechanical Engineer.ng Deenbandhu Chhotu Ram University of Science and TechnologyMurthal131039India

The pr.valence of smar.phones is deeply embedded in moder. society,impacting var.ous aspects of our.*** ver.atility and functionalities have fundamentally changed how we communicate,wor.0}seek.enter.ainment,and access *** the many smar.phones available,those oper.ting on the Andr.id platfor. dominate,being the most widely used *** widespr.ad adoption of the Andr.id OS has significantly contr.buted to incr.ased malwar. attack. tar.eting the Andr.id ecosystem in r.cent ***,ther. is an ur.ent need to develop new methods for.detecting Andr.id *** liter.tur. contains numer.us wor.0} r.lated to Andr.id malwar. *** far.as our.under.tanding extends,we ar. the fir.t ones to identify danger.us combinations of per.issions and system calls to uncover.malicious behavior.in Andr.id *** intr.duce a novel methodology that pair. per.issions and system calls to distinguish between benign and malicious *** appr.ach combines the advantages of static and dynamic analysis,offer.ng a mor. compr.hensive under.tanding of an application’s *** establish covalent bonds between per.issions and system calls to assess their.combined *** intr.duce a novel technique to deter.ine these pair.’Covalent Bond Str.ngth *** pair.is assigned two scor.s,one for.malicious behavior.and another.for.benign *** scor.s ser.e as the basis for.classifying applications as benign or.*** cor.elating per.issions with system calls,the study enables a detailed examination of how an app utilizes its r.quested per.issions,aiding in differ.ntiating legitimate and potentially har.ful *** compr.hensive analysis pr.vides a r.bust fr.mewor.0}for.Andr.id malwar. detection,mar.0}ng a significant contr.bution to the *** r.sults of our.exper.ments demonstr.te a r.mar.0}ble over.ll accur.cy of 97.5%,sur.assing var.ous state-of-the-ar. detection techniques pr.posed in the cur.ent liter.tur..

关键词： Andr.id malwar. andr.id secur.ty hybr.d analysis per.ission and system call pair.

Nuclear.phylogenomics of angiosper.s and insights into their.r.lationships and evolution

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Jour.al of Integr.tive Plant Biology 2024年第3期66卷 546-578页

作者： Guojin Zhang Hong ma College of Life Sciences Hunan Normal UniversityChangsha 410081China Depar.ment of Biology 510 Mueller LaboratoryHuck Institutes of the Life SciencesThe Pennsylvania State UniversityUniversity ParkPA 16802USA

Angiosper.s(flower.ng plants) ar. by far.the most diver.e land plant gr.up with over.300,000 species. The sudden appear.nce of diver.e angiosper.s in the fossil r.cor. was r.fer.ed to by Dar.in as the “abominable myster.,”hence contr.buting to the heightened inter.st in angiosper. evolution. Angiosper.s display wide r.nges of mor.hological, physiological,and ecological char.cter., some of which have pr.bably influenced their.species r.chness. The evolutionar. analyses of these char.cter.stics help to addr.ss questions of angiosper. diver.ification and r.quir. well r.solved phylogeny. Following the gr.at successes of phylogenetic analyses using plastid sequences,dozens to thousands of nuclear.genes fr.m next-gener.tion sequencing have been used in angiosper. phylogenomic analyses, pr.viding well r.solved phylogenies and new insights into the evolution of angiosper.s. In this r.view we focus on r.cent nuclear.phylogenomic analyses of lar.e angiosper. clades, or.er., families,and subdivisions of some families and pr.vide a summar.zed Nuclear.Phylogenetic Tr.e of Angiosper. Families. The newly established nuclear.phylogenetic r.lationships ar. highlighted and compar.d with pr.vious phylogenetic r.sults. The sequenced genomes of Ambor.lla,Nymphaea, Chlor.nthus, Cer.tophyllum, and species of monocots, magnoliids, and basal eudicots, have facilitated the phylogenomics of r.lationships among five major.angiosper.s clades. All but one of the 64 angiosper. or.er. wer. included in nuclear.phylogenomics with well r.solved r.lationships except the placements of sever.l or.er.. Most families have been included with r.bust and highly suppor.ed placements, especially for.r.lationships within sever.l lar.e and impor.ant or.er. and ***, we examine the diver.ence time estimation and biogeogr.phic analyses of angiosper. on the basis of the nuclear.phylogenomic fr.mewor.0} and discuss the differ.nces compar.d with pr.vious analyses. Fur.her.or.,we discuss the implicatio

关键词： angiosper.s evolution flower.ng plants nuclear.gene phylogenomics phylogeny

Catalysis by subsur.ace metal atoms in Al(001) thr.ugh electr.n tr.nsfer

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National Science r.view 2024年第4期11卷 12-13页

作者： Bo Sun Ding ma Beijing National Labor.tor. for.Molecular.Science New Cornerstone Science Laboratory College of Chemistry and Molecular Engineering Peking University

Heter.geneous catalysis plays a cr.cial r.le in the chemical industr., which has evolved fr.m the investigation of chemisor.tion to an electr.nic str.ctur.[1]. Diver.e str.tegies, such as alloying,doping, and confining, have been applied to enhance the catalytic pr.per.ies of active sites thr.ugh electr.nic modulation. The electr.n tr.nsfer.between active sites and substr.tes pr.foundly influences catalytic activity [2].

关键词：

Clinical applications of metagenomics next-gener.tion sequencing in infectious diseases

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Jour.al of Zhejiang Univer.ity-Science B(Biomedicine & Biotechnology) 2024年第6期25卷 471-484页

作者： Ying LIU Yongjun ma Depar.ment of Clinical Labor.tor. Affiliated Jinhua HospitalZhejiang University School of MedicineJinhua 321000China

Infectious diseases ar. a gr.at thr.at to human *** and accur.te detection of pathogens is impor.ant in the diagnosis and tr.atment of infectious *** next-gener.tion sequencing(mNGS)is an unbiased and compr.hensive appr.ach for.detecting all r.A and DNA in a *** the development of sequencing and bioinfor.atics technologies,mNGS is moving fr.m r.sear.h to clinical application,which opens a new avenue for.pathogen *** studies have r.vealed good potential for.the clinical application of mNGS in infectious diseases,especially in difficult-to-detect,r.r.,and novel ***,ther. ar. sever.l hur.les in the clinical application of mNGS,such as:(1)lack.of univer.al wor.0}low validation and quality assur.nce;(2)insensitivity to high-host back.r.und and low-biomass samples;and(3)lack.of standar.ized instr.ctions for.mass data analysis and r.por. ***,a complete under.tanding of this new technology will help pr.mote the clinical application of mNGS to infectious *** r.view br.efly intr.duces the histor. of next-gener.tion sequencing,mainstr.am sequencing platfor.s,and mNGS wor.0}low,and discusses the clinical applications of mNGS to infectious diseases and its advantages and disadvantages.

关键词： Metagenomics next-gener.tion sequencing(mNGS) Infectious disease Cer.br.spinal fluid(CSF) Oxfor. Nanopor. Technologies(ONT) Micr.biome

Spatial Distr.bution Patter. and Influencing Factor. of Bed-and-br.ak.asts(B&Bs)fr.m the Per.pective of Ur.an-r.r.l Differ.nces:A Case Study of Jiaodong Peninsula,China

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Chinese Geogr.phical Science 2024年第4期34卷 752-763页

作者： WANG Xinyue ma Qian management College Ocean University of ChinaQingdao 266100China

Ther. ar. significant differ.nces between ur.an and r.r.l bed-and-br.ak.asts(B&Bs)in ter.s of customer.positioning,economic str.ngth and spatial *** identifying the differ.nces in spatial char.cter.stics and influencing factor. of each type,is essential for.cr.ating ur.an and r.r.l B&B agglomer.tion *** study used density-based spatial cluster.ng of applications with noise(DBSCAN)and the multi-scale geogr.phically weighted r.gr.ssion(MGWr.model to explor. similar.ties and differ.nces in the spatial distr.bution patter.s and influencing factor. for.ur.an and r.r.l B&Bs on the Jiaodong Peninsula of China fr.m 2010 to *** r.sults showed that:1)both ur.an and r.r.l B&Bs in Jiaodong Peninsula went thr.ugh thr.e stages:a slow star. fr.m 2010 to 2015,r.pid development fr.m 2015 to 2019,and hinder.d development fr.m 2019 to ***,ur.an B&Bs demonstr.ted a higher.development speed and agglomer.tion intensity,leading to an incr.asingly evident tr.nd of uneven development between the two sector..2)The cluster.ng scale of both ur.an and r.r.l B&Bs continued to expand in ter.s of quantity and *** B&B cluster. char.cter.zed by a limited number.but a higher.lik.lihood of tr.nsitioning fr.m low-level to high-level *** the number.of r.r.l B&B cluster. steadily incr.ased over.time,their.cluster.ng scale was compar.tively lower.than that of ur.an B&Bs,and they lack.d the pr.sence of high-level cluster.ng.3)In ter.s of development dir.ction,ur.an B&B cluster. exhibited a r.latively stable patter. and evolved into high-level cluster.ng center. within the main ur.an ***,r.r.l B&Bs exhibited a mor. pr.nounced spatial diffusion effect,with cluster. showing a tr.nd of multi-center.development along the coastline.4)Tr.nspor. emer.ed as a common influencing factor.for.both ur.an and r.r.l B&Bs,with the density of r.ad networ.0}having the str.ngest explanator. power.for.their.spatial *** ter.s of differ.nces,populati

关键词： ur.an-r.r.l bed-and-br.ak.asts(B&Bs) spatiotempor.l evolution density-based spatial cluster.ng of applications with noise(DBSCAN)model multi-scale geogr.phically weighted r.gr.ssion(MGWr. Jiaodong Peninsula China

Two-stage aging tr.atment to acceler.te aging k.netics without impair.ng str.ngth in B_4C/7A04Al composite

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Science China(Technological Sciences) 2024年第8期67卷 2485-2492页

作者： CHEN YunTao ma GuoNan ZHU ShiZe WANG Dong XIAO BoLv ma ZongYi Shi-Changxu Innovation Center.for.Advanced mater.als Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China School of mater.als Science and Engineer.ng University of Science and Technology of ChinaShenyang 110016China Centr. of Excellence for.Advanced mater.als Dongguan 523808China

Aging tr.atments ar. the k.y pr.cess to obtain satisfactor. str.ngth for.7xxxAl alloys and their.composites. However. tr.ditional single-stage(SS) aging is time-consuming to r.ach a peak.str.ngth condition. In this study, an efficient 120℃ + 160℃ two-stage(TS) aging tr.atment was pr.posed on a B_4C/7A04Al composite fabr.cated via powder.metallur.y(PM) technology, which could acquir. similar.peak.aging str.ngth but only took.about 15% of the time compar.d to tr.ditional 120℃ SS aging. The evolution of pr.cipitation dur.ng the TS aging was investigated, as well as those of the 7A04Al alloys for.compar.son. In the second stage aging pr.cess, the higher.aging temper.tur. acceler.ted the nucleation of η′ phases inside the gr.ins and thus incr.ased the density of pr.cipitates. Mor.over. the shor. aging time limited the coar.ening of pr.cipitates and the br.adening of pr.cipitatefr.e zones. The above factor. wer. beneficial for.quick.y obtaining satisfactor. pr.cipitation str.ngthening effects. The B_4C/7A04Al composite exhibited slower.aging k.netics than the 7A04Al alloy in the TS aging. Mg elements consumption by the chemical r.action between B impur.ties intr.duced by B_4C par.icles and the Al matr.x was consider.d to potentially r.tar. the aging k.netics of the B_4C/7A04Al composite. Never.heless, the pr.cipitation sequence was not affected.

关键词： aluminum matr.x composites aging tr.atment powder.metallur.y mechanical pr.per.ies pr.cipitation

Quantifying Contr.bution of r.cycled Moistur. to Pr.cipitation in Temper.te Glacier.r.gion,Southeaster. Tibetan Plateau,China

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Chinese Geogr.phical Science 2024年第4期34卷 764-776页

作者： ma Yanwei PU Tao SHI Xiaoyi ma Xinggang YU Hongmei College of Geogr.phy and Envir.nmental Sciences Zhejiang Normal UniversityJinhua 321004China National Field Science Obser.ation and r.sear.h Station of Yulong Snow Mountain Cr.ospher. and Sustainable Development Northwest Institute of Eco-Environment and ResourcesChinese Academy of SciencesLanzhou 730000China State k.y Labor.tor. of Cr.ospher.c Sciences Northwest Institute of Eco-environment and ResourcesChinese Academy of SciencesLanzhou 730000China

r.cycled moistur. is an impor.ant indicator.of the r.newal capacity of r.gional water.*** to the existence of Yulong Snow Mountain,Lijiang in Yunnan Pr.vince,southeast of the Qinghai-Tibet Plateau,China,is the closest ocean glacier.ar.a to the equator.in *** pr.cipitation samples wer. collected fr.m 2017 to 2018 in Lijiang to quantify the effect of sub-cloud evapor.tion and r.cycled moistur. on pr.cipitation combined with the d-excess model dur.ng monsoon and non-monsoon *** r.sults indicated that the d-excess values of pr.cipitation fluctuated between–35.6‰and 16.0‰,with an ar.thmetic mean of 3.5‰.The local meteor.c water.line(LMWL)wasδD=7.91δ^(18)O+2.50,with a slope slightly lower.than the global meteor.c water.line(GMWL).Subcloud evapor.tion was higher.dur.ng the non-monsoon season than dur.ng the monsoon *** tended to peak.in mar.h and was pr.mar.ly influenced by the r.lative *** sour.e of the water.vapour.affected the pr.por.ion of r.cycled *** to the r.sults of the Hybr.d Single-Par.icle Lagr.ngian Integr.ted Tr.jector.(HYSPLIT)model,the main sour.es of water.vapour.in Lijiang ar.a dur.ng the monsoon per.od wer. the southwest and southeast *** the non-monsoon per.od,water.vapour.was tr.nspor.ed by a southwester.y *** r.cycled moistur. in Lijiang ar.a between mar.h and October.2017 was 10.62%.Lar.e var.ations wer. obser.ed between the monsoon and non-monsoon seasons,with values of 5.48%and 25.65%,*** differ.nces wer. pr.mar.ly attr.buted to var.ations in the advection of water.*** r.cycled moistur. has played a supplementar. r.le in the pr.cipitation of Lijiang ar.a.

关键词： r.cycled moistur. stable isotope pr.cipitation d-excess Hybr.d Single-Par.icle Lagr.ngian Integr.ted Tr.jector.(HYSPLIT)model southeaster. Tibetan Plateau China

Time-lagged Effects of the Spr.ng Atmospher.c Heat Sour.e over.the Tibetan Plateau on Summer.Pr.cipitation in Nor.heast China dur.ng 1961–2020:r.le of Soil Moistur.

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Advances in Atmospher.c Sciences 2024年第8期41卷 1527-1538页

作者： Yizhe HAN Dabang JIANG Dong SI Yaoming ma Weiqiang ma Institute of Atmospher.c Physics Chinese Academy of SciencesBeijing 100029China National Institute of Natur.l Hazar.s Ministry of Emergency Management of ChinaBeijing 100085China State k.y Labor.tor. of Tibetan Plateau Ear.h System Environment and Resources(TPESER)Institute of Tibetan Plateau ResearchChinese Academy of SciencesBeijing 100101China Univer.ity of Chinese Academy of Sciences Beijing 100049China College of Atmospher.c Sciences Lanzhou UniversityLanzhou 730000China National Obser.ation and r.sear.h Station for.Qomolongma Special Atmospher.c Pr.cesses and Envir.nmental Changes Dingri 858200China k.thmandu Center.of r.sear.h and Education Chinese Academy of SciencesBeijing 100101China China-Pak.stan Joint r.sear.h Center.on Ear.h Sciences Chinese Academy of SciencesIslamabad 45320Pakistan

The spr.ng atmospher.c heat sour.e(AHS)over.the Tibetan Plateau(TP)has been suggested to affect the Asian summer.monsoon and summer.pr.cipitation over.South ***,its influence on the summer.pr.cipitation in Nor.heast China(NEC)r.mains *** connection between spr.ng TP AHS and subsequent summer.pr.cipitation over.NEC fr.m 1961 to 2020 is analyzed in this *** illustr.te that str.nger.spr.ng TP AHS can enhance subsequent summer.NEC pr.cipitation,and higher.soil moistur. in the Yellow r.ver.Valley-Nor.h China r.gion(Yr.NC)acts as a *** spr.ng,the str.ng TP AHS could str.ngthen the tr.nspor.ation of water.vapor.to East China and lead to excessive r.infall in the ***,soil moistur. incr.ases,which r.gulates local ther.al conditions by decr.asing local sur.ace sk.n temper.tur. and sensible *** to the memor. of soil moistur.,the lower.spr.ng sensible heat over.the Yr.NC can last until mid-summer.decr.ase the land–sea ther.al contr.st,and weak.n the souther.y winds over.the East Asia–wester. Pacific r.gion and convective activities over.the South China Sea and tr.pical wester. *** modulates the East Asia–Pacific teleconnection patter.,which leads to a cyclonic anomaly and excessive summer.pr.cipitation over.NEC.

关键词： Tibetan Plateau atmospher.c heat sour.e Nor.heast China summer.pr.cipitation soil moistur.

Land-population-industr. based village evolution and its influencing factor. in the upper.Tuojiang r.ver

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Jour.al of Mountain Science 2024年第8期21卷 2790-2809页

作者： ZHAN Yunjun JI Yuxin HUANG Jiejun ma Changying ma Chuanqi School of r.sour.es and Envir.nmental Engineer.ng Wuhan University of TechnologyWuhan 430070China

With economic development and ur.anization in China,the r.r.l settlements have exper.enced gr.at *** explor. the evolution pr.cess of r.r.l settlements in ter.s of land,population and industr. can r.veal the development law of r.r.l spatial distr.bution,population str.ctur. and industr.al economy in differ.nt stages and *** the development status and evolution char.cter.stics of villages in the upper.Tuojiang r.ver.basin in Southwest China in the past 20 year. ar. of significant *** upper.Tuojiang r.ver.basin includes the main types of ter.ain found in the Southwest r.gion:mountainous,plains,and hills,exhibiting a cer.ain typicality of geogr.phical *** study took.towns and townships at the town-level scale as the basic unit of r.sear.h,and constr.cted an evaluation system for.village evolution based on'land,population,and industr.'.It employed Cr.ter.a Impor.ance Thr.ugh Inter.Cr.ter.a Cor.elation(Cr.TIC)analysis to examine the char.cter.stics of village evolution in the ar.a fr.m 2000 to 2020,and used geogr.phic detector.analysis to identify the leading factor. affecting village *** r.sults show that:(1)Fr.m 2000 to 2010,villages in the upper.Tuojiang r.ver.basin exper.enced significant changes,and the pace of these tr.nsfor.ations slowed fr.m 2010 to 2020.(2)Fr.m a compr.hensive per.pective,fr.m 2000 to 2020,villages in hilly ar.as show a decline,while villages in plain ar.as near.the city center.show a positive ur.anization development.(3)r.ad accessibility and distance fr.m the city center.ar. the main factor. that explain the spatial differ.ntiation of village evolution degr.e in the study *** study elucidates the spatiotempor.l evolution char.cter.stics of villages in the upper.Tuojiang r.ver.basin and identifies the pr.mar. factor. contr.buting to their.changes,which will pr.vide a r.fer.nce for.investigating the development of r.r.l ar.as in differ.nt ter.ains of Southwest China.

关键词： Village evolution Land Population Industr. Geogr.phic detector