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Pictorial research of pancreas with artificial intelligence and simulacra in the work. of Fellini

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Artificial Intelligence in Medical Imaging 2021年第6期2卷 115-117页

作者： Hirok. tahara Faculty of Integrated Human Studies Kyoto UniversityKyoto 606-8501Japan

This is the consideration recalled from my reading of Acute pancreatitis:A pictorial review of early pancreatic fluid collections by *** perspective related to the work. of Fellini might be able to contribute the futu... 详细信息

关键词： Pancreatic diseases Medical imaging Artificial intelligence Baudrillard Simulacra Fellini

Brazilian savanna re-establishment in a monoculture forest:diversity and environmental relations of native regenerating understory in Pinus caribaea Morelet. stands

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Journal of Forestry Research 2015年第3期26卷 571-579页

作者： Gasto Viegas de Pinho Júnior AndréR. Terra Nascimento Barbara tahara Valverde Lucas H. Clemente Elementary/High Schools in Uberlndia UberlndiaMinas Gerais 38412-436 Brazil Universidade Federal de Uberlndia UberlndiaMinas Gerais 38412-436 Brazil Avenida Ortizio Borges 2836 Bairro Santa MnicaUberlndia Minas Gerais 38412-436 Brazil

In this paper we analyze and compare natural regeneration in shrub-tree community in three areas below Pinus caribaea stands and a natural area （cerrado sensu stricto）. We also analyze the influence of biophysical and environmental variables on the distribution of regenerating shrub-tree species. The areas were analyzed and compared in relation to dispersal syndromes as well, being zoochory and anemochory the prevailing syndroms in the four areas. The sites below P. caribaea show a heterogeneous regen- eration with the number of species ranging from 18 to 42. We analyzed the influence of the biophysical and envi- ronmental variables performing a canonical correspon- dence analyses, being found significant values for variables distance from remnant and basal area. The species Si- paruna guianensis, Miconia albicans, Xylopia aromatica, Sclerolobium paniculatum, Casearia sylvestris and P. caribaea were the most importante ones in the four areas,

关键词： Native regeneration Cerrado Commercialforests Multivariate analysis Plant ecology

Starch Orodispersible Film Loaded with Melatonin for Human Supplementation

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Journal of Renewable Materials 2024年第7期12卷 1343-1354页

作者： Fabio Tamanini Tatiane Zucchini de Souza Creusa Sayuri tahara Amaral Antônio JoséFelix Carvalho Eliane Trovatti Department of Health and Biological Sciences University of Araraquara(UNIARA)São Paulo14801-340Brazil Department of Materials Engineering São Carlos School of EngineeringUniversity of São PauloSão Paulo13563-120Brazil

An innovative pharmaceutical form for administering melatonin,based on starch orodispersibleﬁlm(ODF),was designed and *** composition of the ODF included starch as the polymer matrix,the active drug melatonin,and a ***,a natural hormone produced by the pineal gland in the brain,can be absorbed by passive diffusion across the mucous membrane,resulting in improved bioavailability when compared to conventional oral *** study shows a simple and efﬁcient method for preparing melatonin-loaded orodispersibleﬁlms with a physically stable and commercially viable matrix,suitable for use in the pharmaceutical ***ﬁlms were prepared by treating the starch with microwave irradiation,followed by plasticization with glycerol,melatonin loading and drying by solvent *** tests showed theﬁlms’robustness,with a modulus of approximately 97 MPa,indicating good handling *** uptak. analysis showed fast water absorption,reaching about 150%within 2 min,indicating its fast oral disintegration *** tests in artiﬁcial saliva and dissolution studies indicated the release of the drug in min-utes,indicating the potential properties of theﬁlm for oral drug *** the best of our k.owledge,there is no melatonin ODF based on starch described in the literature.

关键词： Starch orodispersibleﬁlm melatonin drug delivery

Hiroomi的乐尚生活——设计师Hiroomi tahara与作品

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现代装饰（家居） 2013年第2期 134-138页

作者： Hiroomi tahara Danya

在Hiroomi看来,强调与使用者的互动关系有助于建立人与设计之间的情感。这需要从产品的外型体现,也需要从产品的功能性进行展现。如产品Towel所展现的简约风格,仅用若干金属栓与一条尼龙绳制作完成,而产品所透露出的DIY精神,更增加了使... 详细信息

在Hiroomi看来,强调与使用者的互动关系有助于建立人与设计之间的情感。这需要从产品的外型体现,也需要从产品的功能性进行展现。如产品Towel所展现的简约风格,仅用若干金属栓与一条尼龙绳制作完成,而产品所透露出的DIY精神,更增加了使用时的乐趣,用户可以从安装开始感受到产品所带来的创意。

关键词： Hiroomi tahara 简约风格互动关系灯架日本大学藤蔓节能灯泡纺织材料柔软性外型设计

Preparation of silymarin nanocrystals using a novel high pressure crystallization technique and evaluation of its dissolution and absorption properties

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Asian Journal of Pharmaceutical Sciences 2016年第1期11卷 211-212页

作者： Risak. Onodera Tomohiro Hayashi Tatsuo Nak.mura k.ori Aibeb k.hei tahara Hirofumi Tak.uchi Gifu Pharmaceutical University 1-25-4 Daigaku-nishiGifu 501-1196Japan FANCL Corporation 12-13 Kamisinano Totsuka-kuYokohamaKanagawa 244-0806Japan

Oral bioavailability of drug is limited by the factors such as the membrane permeability, the solubility, the dissolution rate and so on (1)In case of a poorly water-soluble drug, its solubility and dissolution rate is a critical factor for its oral *** various techniques for enhancing solubility or dissolution properties, physical modification of drug products such as reducing the particle size is one of common approaches [2].

关键词： PureNano^(■) Silymarin Hydroxypropyl cyclodextrin Crystallization

Preparation of bromfenac-loaded liposomes modified with chitosan for ophthalmic drug delivery and evaluation of physicochemical properties and drug release profile

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Asian Journal of Pharmaceutical Sciences 2013年第2期8卷 104-109页

作者： Toshimasa Tsuk.moto k.hei Hironak. Tak.ya Fujisawa Daik. Yamaguchi k.hei tahara Yuichi Tozuk. Hirofumi Tak.uchi Laboratory of Pharmaceutical Engineering Gifu Pharmaceutical University1-25-4 Daigaku-nishiGifu 501-1196Japan Laboratory of Formulation Design and Pharmaceutical Technology Osaka University of Pharmaceutical SciencesOsakaJapan

The purpose of this study was to design a submicron-sized liposomal non-steroidal antiinflammatory drug(NSAID)preparation that targets the retina via topical instillation of eye ***(BRF)-loaded liposomes were prepared using the calcium acetate gradient *** sizes and encapsulation efficiencies were optimized by screening several liposome formulations of lipid,drug concentration,and buffer *** entrapment efficiency was greater than 90%using this method,and was low using conventional hydration *** initial BRF loading using the pH gradient method caused aggregation of *** circumvent aggregation,the negatively charged lipid dicetylphosphate was incorporated into liposomes,which formed anion layer preventing *** of BRF from liposomes was sustained for several hours depending on lipid concentration,inner water phase,initial drug amounts,and surface *** modification with chitosan(CS),a mucoadhesive cationic polymer,was achieved using electrostatic interactions of negatively charged *** optimal concentration of CS for evasion of liposome aggregation was 0.15%.

关键词： NSAIDs pH Gradient method Surface modification Chitosan Eye drop

Prophylactic managements of hepatitis B viral infection inliver transplantation

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World Journal of Gastroenterology 2016年第1期22卷 165-175页

作者： Tak.shi Onoe Hiroyuk. tahara Yuk. Tanak. Hidek. Ohdan Division of Applied Immunobiology Institute for Clinical ResearchNational Hospital OrganizationKure Medical Center/Chugoku Cancer CenterHiroshima 737-0023Japan Gastroenterological and Transplant Surgery Applied Life SciencesInstitute of Biomedical and Health SciencesHiroshima UniversityHiroshima 734-8551Japan

Liver transplantation(LT)is a considerably effective treatment for patients with end-stage hepatitis B virus(HBV)-related liver ***,HBV infection often recurs after LT without *** the1990s,the treatment for preventing HBV reinfection after LT has greatly progressed with the introduction of hepatitis B immunoglobulin(HBIG)and nucleos(t)ide analogues(NAs),resulting in improved patient *** combination therapy consisting of high-dose HBIG and lamivudine is highly efficacious for preventing the recurrence of HBV infection after LT and became the standard prophylaxis for HBV ***,mainly due to the high cost of HBIG treatment,an alternative protocol for reducing the dose and duration of HBIG has been ***,combination therapy using low-dose HBIG and NAs is considered as the most efficacious and cost-effective prophylaxis for post-LT HBV ***,NA monotherapy and withdrawal of HBIG from combination therapy,along with the development of new,potent high genetic barrier NAs,have provided promising efficacy,especially for low-risk.*** review summarizes the prophylactic protocol and their efficacy including prophylaxis of de novo HBV infection from anti-HBc antibody-positive *** addition,challenging approaches such as discontinuation of all prophylaxis and active immunity through hepatitis B vaccination are discussed.

关键词： Liver transplantation Hepatitis B infection prophylaxis nucleos(t)ide analogue anti-hepatitis Bimmunoglobulin

Cellular and molecular aspects of gastric cancer

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World Journal of Gastroenterology 2006年第19期12卷 2979-2990页

作者： Malcolm G Smith Georgina L Hold Eiichi tahara Emad M El-Omar Department of Medicine and Therapeutics Aberdeen University ForesterhillAberdeen AB25 2ZDScotlandUnited Kingdom

Gastric cancer remains a global k.ller with a shifting burden from the developed to the developing world. The cancer develops along a multistage process that is defined by distinct histological and pathophysiological phases. Several genetic and epigenetic alterations mediate the transition from one stage to another and these include mutations in oncogenes, tumour suppressor genes and cell cycle and mismatch repair genes. The most significant advance in the fight against gastric caner came with the recognition of the role of Helicobacter pylori （H pylori） as the most important acquired aetiological agent for this cancer. Recent work.has focussed on elucidating the complex host/microbial interactions that underlie the neoplastic process. There is now considerable insight into the pathogenesis of this cancer and the prospect of preventing and eradicating the disease has become a reality. Perhaps more importantly, the study of H pylori-induced gastric carcinogenesis offers a paradigm for understanding more complex human cancers. In this review, we examine the molecular and cellular events that underlie Hpyloriinduced gastric cancer.

关键词： Gastric cancer Helicobacter pylori Hostmicrobial interactions Inflammation Molecular mechanisms Host genetics

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小麦旗叶脱落酸含量的直接酶免疫测定法

国外农学（麦类作物） 1992年第5期 27-29页

作者： Mak.to tahara 刘保立

本研究旨在探索一种便于大规模筛选小麦种质的方法。这种方法是以叶组织中ABA含量及其积累速率为选择标准的。利用直接酶免疫法研究了提取时间、C_(18)反向色层、溶剂挥发以及样本提取液的稀释对ABA定量的影响。结果表明,提取溶剂的完... 详细信息

本研究旨在探索一种便于大规模筛选小麦种质的方法。这种方法是以叶组织中ABA含量及其积累速率为选择标准的。利用直接酶免疫法研究了提取时间、C_(18)反向色层、溶剂挥发以及样本提取液的稀释对ABA定量的影响。结果表明,提取溶剂的完全挥发不影响ABA测定。利用800ml/L甲醇从小麦叶片提取ABA需用24h。甲醇稀释浓度≤80ml/L时,消除了由甲醇造成的对酶免疫法的干扰。稀释曲线的对应性测试或利用C_(18)反向色层分离法对叶提取液的部分纯化都未检测到对酶免疫法的明显抑制因子。

关键词：小麦旗叶脱落酸酶免疫测定