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Neural Regeneration Research 2015年第10期10卷 1589-1590页

作者： Dong hoon Hwang Hae Young Shin Byung Gon kim Department of Brain Science Ajou University School of Medicine Neuroscience Graduate Program Department of Biomedical Sciences Ajou University Graduate School of Medicine Neurology Ajou University School of Medicine

Traumatic injuries to spinal cord elicit diverse signaling pathways leading to unselective and complex pathological outcomes：death of multiple classes of neural cells,formation of cystic cavities and glial scars,disruption of axonal connections,and demyelination of spared axons,all of which can contribute more or less to debilitating functional impairments found in patients with spinal cord injury.

关键词： NSCs Fortuitous benefits of activity-based rehabilitation in stem cell-based therapy for spinal cord repair enhancing graft survival stem cell

An Efficient Stacked Ensemble Model for Heart Disease Detection and Classification

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Computers, Materials & Continua 2023年第10期77卷 665-680页

作者： Sidra Abbas Gabriel Avelino Sampedro Shtwai Alsubai Ahmad Almadhor Tai-hoon kim Department of Computer Science COMSATS UniversityIslamabadPakistan College of Computer Studies De La Salle UniversityManila1004Philippines Faculty of Information and Communication Studies University of the Philippines Open UniversityLos Banos4031Philippines College of Computer Engineering and Sciences Prince Sattam bin Abdulaziz UniversityAlkharjSaudi Arabia Department of Computer Engineering and Networks College of Computer and Information SciencesJouf UniversitySakaka72388Saudi Arabia School of Electrical and Computer Engineering Yeosu CampusChonnam National UniversityYeosu-si59626Korea

Cardiac disease is a chronic condition that impairs the heart’s *** includes conditions such as coronary artery disease,heart failure,arrhythmias,and valvular heart *** conditions can lead to serious complications and even be life-threatening if not detected and managed in *** have utilized Machine Learning(ML)and Deep Learning(DL)to identify heart abnormalities swiftly and *** approaches have been applied to predict and treat heart disease utilizing ML and *** paper proposes a Machine and Deep Learning-based Stacked Model(MDLSM)to predict heart disease *** approaches such as eXtreme Gradient Boosting(XGB),Random Forest(RF),Naive Bayes(NB),Decision Tree(DT),and KNearest Neighbor(KNN),along with two DL models:Deep Neural Network(DNN)and Fine Tuned Deep Neural Network(FT-DNN)are used to detect heart *** models rely on electronic medical data that increases the likelihood of correctly identifying and diagnosing heart ***-known evaluation measures(i.e.,accuracy,precision,recall,F1-score,confusion matrix,and area under the Receiver Operating Characteristic(ROC)curve)are employed to check the efficacy of the proposed *** reveal that the MDLSM achieves 94.14%prediction accuracy,which is 8.30%better than the results from the baseline experiments recommending our proposed approach for identifying and diagnosing heart disease.

关键词： Deep neural network heart disease healthcare machine learning stacking

Dynamic deformation behavior and microstructural evolution during high-speed rolling of Mg alloy having non-basal texture

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Journal of Materials Science & Technology 2019年第4期35卷 473-482页

作者： Sang-hoon kim Jeong Hun Lee Chong Soo Lee Jonghun Yoon Sung Hyuk Park School of Materials Science and Engineering Kyungpook National University Ulsan Regional Division Korea Institute of Industrial Technology Graduate Institute of Ferrous Technology Pohang University of Science and Technology Department of Mechanical Engineering Hanyang University

The dynamic deformation behaviors and resultant microstructural variations during high-speed rolling(HSR) of a Mg alloy with a non-basal texture are investigated. To this end, AZ31 alloy samples in which the basal poles of most grains are predominantly aligned parallel to the transverse direction(TD) are subjected to hot rolling with different reductions at a rolling speed of 470 m/min. The initial grains with a TD texture are favorable for {10–12} twinning under compression along the normal direction(ND); as a result, {10–12} twins are extensively formed in the material during HSR, and this consequently results in a drastic evolution of texture from the TD texture to the ND texture and a reduction in the grain size. After the initial grains are completely twinned by the {10–12} twinning mechanism, {10–11} contraction twins and {10–11}-{10–12} double twins are formed in the {10–12} twinned grains by further *** the contraction twins and double twins have crystallographic orientations that are favorable for basal slip during HSR, dislocations easily accumulate in these twins and fine recrystallized grains nucleate in the twins to reduce the increased internal strain energy. Until a rolling reduction of 20%, {10–12}twinning is the main mechanism governing the microstructural change during HSR, and subsequently,the microstructural evolution is dominated by the formation of contraction twins and double twins and the dynamic recrystallization in these twins. With an increase in the rolling reduction, the average grain size and internal strain energy of the high-speed-rolled(HSRed) samples decrease and the basal texture evolves from the TD texture to the ND texture more effectively. As a result, the 80% HSRed sample, which is subjected to a large strain at a high strain rate in a single rolling pass, exhibits a fully recrystallized microstructure consisting of equiaxed fine grains and has an ND basal texture without a TD texture component.

关键词： Magnesium alloy High-speed rolling Texture Dynamic recrystallization Twinning

Long-term clinical outcome between beta-blocker with ACEI or ARB in patients with NSTEMI who underwent PCI with drug-eluting stents

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Journal of Geriatric Cardiology 2019年第3期16卷 280-290页

作者： Yong hoon kim Ae-Young Her Eun-Seok Shin Myung Ho Jeong Division of Cardiology Department of Internal MedicineKangwon National University School of MedicineChuncheonSouth Korea Division of Cardiology Department of Internal MedicineUlsan Medical CenterUlsan HospitalUlsanSouth Korea Chonnam National University Hospital GwangjuSouth Korea

Background Because limited comparative data are available,we decided to compare 2-year major clinical outcomes between beta-blockers (BB) with angiotensin converting enzyme inhibitors (ACEI) and BB with angiotensin receptor blockers (ARB) therapy in patients with non-ST-segment elevation myocardial infarction (NSTEMI) after percutaneous coronary intervention (PCI) with drug-eluting stents (DES).Methods A total 11,288 NSTEMI patients who underwent PCI with DES were enrolled and they were divided into two groups,the BB with ACEI group (n = 7600) and the BB with ARB group (n = 3688).The major clinical endpoint was the occurrence of major adverse cardiac events (MACE) defined as all-cause death,recurrent myocardial infarction (re-MI),total revascularization [target lesion revascularization (TLR),target vessel revascularization (TVR),non-TVR] rate during the 2-year follow-up *** After propensity score-matched (PSM) analysis,two PSM groups (3317 pairs,n = 6634,C-statistic = 0.695) were *** the cumulative incidences of all-cause death,cardiac death,TLR,and non-TVR were similar between the two groups,MACE (HR = 0.832,95% CI: 0.704?0.982,P = 0.030),total revascularization rate (HR = 0.767,95% CI: 0.598?0.984,P = 0.037),and TVR rate (HR = 0.646,95% CI: 0.470?0.888,P = 0.007) were significantly lower in the BB with ACEI group after *** In this study,we suggest that the combination of BB with ACEI may be beneficial for reducing the cumulative incidences of MACE,total revascularization rate,and TVR rather than the BB with ARB after PCI with DES in NSTEMI patients.

关键词： Angiotensin converting enzyme inhibitor Angiotensin receptor blocker Beta-blocker Myocardial infarction

A comparison of desensitization methods: Rituximab with/without plasmapheresis in ABO-incompatible living donor liver transplantation

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Hepatobiliary & Pancreatic Diseases International 2018年第2期17卷 119-125页

作者： Eung Chang Lee Seong hoon kim Jae Ryong Shim Sang-Jae Park Center for Liver Cancer National Cancer Center

Background: Plasmapheresis is a desensitization method used prior to ABO-incompatible(ABO-I) living donor liver transplantation. However, studies on its usefulness in the rituximab era are ***: Fifty-six adult patients underwent ABO-I living donor liver transplantation between January2012 and October 2015. A single dose of rituximab(300 mg/m~2) was administered 2 weeks before surgery with plasmapheresis in all patients until February 2014(RP group, n = 26). Patients were administered rituximab only, without plasmapheresis between March 2014 and October 2015(RO group, n = 30).Results: The 6-, 12-and 18-month overall survival rates were 92.3%, 80.8% and 76.9% in the RP group and 96.6%, 85.4% and 85.4% in the RO group, respectively(P = 0.574). When the initial isoagglutinin titers < 16, neither group showed a rebound rise of isoagglutinin titers. For patients with initial isoagglutinin titers ≥ 16, the rebound rise of isoagglutinin titers was more prominent in the RP group. There was no difference in time-dependent changes in B cell subpopulations and ABO-I-related ***: Sufficient desensitization for ABO-I living donor liver transplantation can be achieved using rituximab alone. This desensitization strategy does not affect the isoagglutinin titers, ABO-I-related complications and patient survival.

关键词： Desensitization Rituximab Plasmapheresis ABO-incompatibility Living donor Liver transplantation

Immediate secondary rhinoplasty using a folded dermofat graft for resolving complications related to silicone implants: A case report

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World Journal of Clinical Cases 2024年第14期12卷 2426-2430页

作者： hoon kim Jong Hyup kim In Chang Koh Soo Yeon Lim Department of Plastic and Reconstructive Surgery Konyang University HospitalUniversity of Konyang College of MedicineMyunggok Medical Research InstituteDaejeon 35365South Korea

BACKGROUND Various surgical techniques have been developed to enhance the nose shapes of Asian *** implant augmentation rhinoplasty is widely used because it is relatively easy to perform and often yields satisfactory ***,this technique may lead to complications,including ischemia,necrosis,and *** most appropriate management of these complications,including infection,is immediate implant removal and revision surgery once the accompanying inflammation has ***,the patient may experience distress from nasal deformities during the intervention *** SUMMARY Herein,we describe the case of a patient who underwent a secondary dorsal augmentation,with a folded dermofat graft harvested from the inguinal area and simultaneous implant removal,successfully preventing dimpling of the nasal *** This surgical method can effectively manage implant-related complications following augmentation rhinoplasty using a silicone implant and provide satis-factory patient outcomes.

关键词： Complications Nose deformities Acquired Rhinoplasty Dermofat Surgery Plastic Case report

A renormalization group approach to crowd psychology and inter-group coupling in social many-body systems

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Chinese Science Bulletin 2012年第2期57卷 247-252页

作者： kim Chul Koo LEE Kong-Ju-Bock CHUNG Myung-hoon Institute of Physics and Applied Physics Yonsei University Department of Physics Ewha Woman's University Department of Physics Hongik University

By adopting majority rule within a renormalization group approach,we can show that the strength of inter-group interaction in a social system either grows or shrinks monotonically with increasing group size,depending on the initial coupling strength of individuals in the *** contrasts with the findings of previous studies in which the strength of the interaction grows with group size regardless of the initial *** approach clearly demonstrates that the phenomena of crowd psychology,such as an extreme anti-reaction between different ethnic or ideological groups,could be a consequence of the many-particle nature of social systems when the initial strength of the interaction is larger than a critical *** effect of neutral opinion holders is critically examined using the spin-one Ising *** critical size of the population of neutral opinion holders,that can prevent crowd polarization,depends on the block spin rule.

关键词：重整化群方法社会制度耦合强度从众心理多体系统群体相互作用初始强度

Current status of endoscopic submucosal dissection for the management of early gastric cancer:A Korean perspective

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World Journal of Gastroenterology 2011年第21期17卷 2592-2596页

作者： hoon Jai Chun Bora Keum Ji Hyun kim Sang Young Seol Division of Gastroenterology and Hepatology Department of Internal MedicineKorea University Anam HospitalKorea University College of MedicineSeoul 136-705South Korea Division of Gastroenterology and Hepatology Department of Internal MedicineInje University College of MedicineBusan 614-735South Korea

The early diagnosis of gastric cancer allows patients and physicians to pursue the option of endoscopic resection,which is significantly less invasive than conventional surgical *** Korea,the use of endoscopic submucosal dissection(ESD) has been increasing,and many reports on ESD have been *** addition,Korean gastroenterologists from several hospitals performing ESD have conducted formal meetings to discuss useful information regarding ***,we discuss the Korean experience with ESD,including outcomes and prospects of endoscopic treatments.

关键词： Early gastric cancer Endoscopic submucosal dissection Endoscopic mucosal resection

Transient involuntary movement disorder after spinal anesthesia: A case report

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World Journal of Clinical Cases 2021年第26期9卷 7917-7922页

作者： Giyoung Yun Eunsoo kim Wangseok Do Young-hoon Jung Hyun-Ju Lee Yesul kim Department of Anesthesia and Pain Medicine Biomedical Research InstitutePusan National University HospitalBusan 49241South Korea Department of Anesthesia and Pain Medicine Pusan National UniversitySchool of MedicineYangsan 50612South Korea

BACKGROUND Spinal anesthesia is commonly used for various *** many complications occur after induction of spinal anesthesia,involuntary movement is an extremely rare *** SUMMARY Herein,we report the case of a 54-year-old healthy male patient who experienced involuntary movements after intrathecal injection of local *** patient had undergone metal implant removal surgery in both the lower extremities;7 h after intrathecal hyperbaric bupivacaine administration,involuntary raising of the left leg began to occur every 2 *** the movement disorder appeared,the patient was conscious and *** other specific symptoms were noted in the physical examination conducted immediately after the involuntary leg raising started;moreover,the patient's motor and sensory assessments were *** symptom gradually *** hours after the symptom first occurred,its frequency decreased to approximately once every three *** days postoperatively,the symptoms had completely disappeared without *** Anesthesiologists should be aware that movement disorders can occur after spinal anesthesia and be able to identify the cause,such as electrolyte imbalance or epilepsy,since immediate action may be required for ***,it is crucial to know that involuntary movement that develop following spinal anesthesia is mostly self-limiting and may not require additional costly examinations.

关键词： Movement disorder Spinal anesthesia Bupivacaine Dexmedetomidine Case report

Laser-Induced Indium-Diffusion into Cadmium Sulfide Thin Film for Solar Cell Applications

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Chinese Physics Letters 2012年第12期29卷 185-187页

作者： kim Nam-hoon MYUNG Kuk Do LEE Woo-Sun Department of Electrical Engineering Chosun UniversityGwangju 501-759Republic of Korea

Laser-induced diffusion is employed to dope indium(In)into sputtering-deposited cadmium sulfide(CdS)thin *** increased optical band gap energy from 2.52 to 2.60 eV with maintenance of high optical transmittance about 60 nm in the 200-nm-thick films,the enhanced mobility over 42.5 cm^(2)/V·s,and the decreased resistivity to 1.42×10^(-3)Ω·cm are successfully obtained to be advantageous for a window layer in solar cells.

关键词： Diffusion resistivity sulfide