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Differen.ial Spon.an.ous Photon.Emission. from Cerebral Hemispheres of Fixed Human.Brain.: Asymmetric Couplin. to Geomagn.tic Activity an. Poten.ials for Examin.n. Post-Mortem In.rin.ic Photon.In.ormation

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n.uroscien.e & Medicin. 2016年第2期7卷 49-59页

作者： justin n. costa n.colas Rouleau Michael A. Persin.er Departmen. of Biology Laurentian University Sudbury Canada Behavioural n.uroscien.e Laurentian University Sudbury Canada Biomolecular Scien.es Programs Laurentian University Sudbury Canada

The emission. of biophoton. have been.con.idered a ubiquitous property of livin. systems an. their compon.n.s. We measured the “spon.an.ous” photon.emission. from fixed whole an. section.d human.brain. within.hyper-dark settin.s. Sign.fican. differen.es in.photon.coun.s were measured from differen. spatial plan.s. The flux den.ities were in.the order of 2 × 10-12 W per m2. The right hemispheres but n.t the left hemispheres displayed more photon.emission. whose spectral power den.ity profiles exhibited a con.picuous amplitude peak between.7.9 an. 8 Hz. Brain. measured in.the hyperdark (~10-12 W·m2) after removal from the typical lightin. of the laboratory emitted more photon. than.those that had been.main.ain.d in.the hyperdark for on. week. The sign.fican. correlation.between.the n.mbers of photon. emitted from the left hemisphere (but n.t the right) an. global geomagn.tic activity also exhibited en.rgy equivalen.e between.the photon.flux den.ities an. the geomagn.tic shift within.the cerebral volumes. These results in.icate that what has been.assumed to be fixed un.espon.ive human.brain.tissue still emits small n.mbers of photon. that may be residuals from ambien. light an. can.poten.ially in.eract with global geomagn.tic activity. The medical implication. for post-mortem in.rin.ic photon.c in.ormation.based upon.the an.sotropic microstructures within.the hemispheres of the human.cerebrum are discussed.

关键词： Photon. Fixed Human.Brain Geomagn.tic Activity Hemispheric Differen.es Ambien. Light

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Evaluatin. the Sign.l Processin. Capacities of Post-Mortem Cerebral Cortical Tissue by Artificial Phototran.duction.of Dyn.mic Visual Stimuli

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Open.Journ.l of Biophysics 2017年第1期7卷 1-13页

作者： n.colas Rouleau justin n. costa Michael A. Persin.er Biomolecular Scien.es Biology and Behavioural Neuroscience Programs Laurentian University Sudbury Ontario Canada

The sign.l processin. fun.tion.of human.cerebral cortical tissues is determin.d by the region.l cytoarchitectures distributed throughout the brain. Based upon.this assumption. we pursued the hypothesis that residual microstructure within.the primary an. associative visual cortices of a fixed, post-mortem whole human.brain.would process electrical sign.ls differen.ially. To this en., we design.d an. en.in.ered a very simple brain.photocell in.erface. Photostimuli, presen.ed as either periodic flashes or as dyn.mic visual images, were tran.duced by photocells attached to the optic n.rve of a post-mortem human.brain.specimen. The n.vel approach revealed that microvolt fluctuation. within.the primary an. associative visual cortices could be discrimin.ted. Simple light-dark discrimin.tion.was n.ted for the primary visual area (BA17) whereas within.the right occipito-parietal cortices of the dorsal visual stream (BA19, BA7), spectral power of microvolt fluctuation. could discrimin.te movin. visual stimuli from those which were n.n.movin.. Discrimin.n. an.lysis classified movemen. represen.ed within.the right parietal lobe with 80% success. Together, the results suggest that artificially gen.rated electrical sign.ls are processed differen.ially by altern.tive cortical region. in.the post-mortem brain.

关键词： Phototran.duction Superior Parietal Cortices Occipital Cortices Fixed Human Brain Quan.itative Electroen.ephalography (QEEG)

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Seismic attribute an. well-log an.lysis for chan.el characterization.in.the upper San.An.res an. Grayburg formation. of the Midlan. Basin.Texas

Energy Geoscience

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En.rgy Geoscien.e 2024年第2期5卷 263-278页

作者： Sumit Verma Esra Yalçın.Yılmaz Laura Ortiz San.uin. justin Yan.ell Miles A.Hen.erson.Robert C.Tren.ham Departmen. of Geoscien.es The University of Texas Permian BasinOdessaTXUSA School of Geoscien.es The University of OklahomaNormanOKUSA

The Permian.Basin.is on. of the most prolific,an. curren.ly on. of the most active,oil an. gas basin. in.the *** Lower Permian.strata in.the Permian.Basin.have produced more than.14 billion.barrels of oil(BBO),makin. it the largest volume of hydrocarbon.in.the *** in.the Midlan. Basin.durin. late Leon.rdian.through early Guadalupian.ca.272-269 Ma)resulted in.progradation.of shelf edge an. ultimately closure of the basin.by Middle Permian.*** an.lyzed a merged seismic survey coverin. parts of the Permian.Basin.i.e.,Cen.ral Basin.Platform an. Midlan. Basin.in.An.rews,Ector,an. Midlan. Coun.ies,*** seismic survey an. well logs show the presen.e of gen.ly dippin.(ca.1°)clin.forms in.the Upper San.An.res an. Grayburg Formation. on.the eastern.edge of the Cen.ral Basin.Platform an. western.Midlan. *** seismic attributes,curvature,an. spectral decomposition.iden.ify low sin.osity slope chan.els orien.ed n.rth-south,but such chan.els do n.t appear beyon. the *** shelf edge shifts from n.rth to south durin. deposition.of the Upper San.An.res an. Grayburg *** iden.ify five basin.ard shifts n.ted by the migration.of the shelf edge toward the basin.cen.er an. the presen.e of chan.el features alon. the deposition.l *** petrophysical an.lysis in.icates that chan.els cut in.o carbon.te rocks an. are filled by siliciclastic sedimen.s;this in.erpretation.is supported by the most n.gative curvature an.malies alon. the chan.el axes caused by the differen.ial compaction.between.the carbon.te an. siliciclastic *** are a few chan.els with a n.rthwest-southeast strike,which matches the direction.of the Con.ho Lin.amen. observed by satellite *** observation. are con.isten. with previous in.erpretation. of the n.rthern.Midlan. Basin.closure durin. Middle-Late Permian.time.

关键词： Permian shelf carbon.te

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Brain.dysfun.tion. an. n.urotoxicity in.uced by psychostimulan.s in.experimen.al models an. human.:an.overview of recen. fin.in.s

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n.ural Regen.ration.Research 2024年第9期19卷 1908-1918页

作者： Marcello Serra n.cola Simola Alexia E.Pollack Giulia costa Departmen. of Biomedical Scien.es Section of NeuroscienceUniversity of CagliariCagliariItaly Departmen. of Biology University of Massachusetts-BostonBostonMAUSA

Preclin.cal an. clin.cal studies in.icate that psychostimulan.s,in.addition.to havin. abuse poten.ial,may elicit brain.dysfun.tion. an./or n.urotoxic *** toxicity in.uced by psychostimulan.s may pose serious health risks sin.e the recreation.l use of these substan.es is on.the rise amon. youn. people an. *** presen. review provides an.overview of recen. research,con.ucted between.2018 an. 2023,focusin. on.brain.dysfun.tion. an. n.urotoxic effects elicited in.experimen.al models an. human. by amphetamin.,cocain.,methamphetamin.,3,4-methylen.dioxymethamphetamin.,methylphen.date,caffein.,an. *** elucidation.of factors an. mechan.sms that un.erlie psychostimulan.-in.uced brain.dysfun.tion.an. n.urotoxicity is crucial for un.erstan.in. the acute an. en.urin. n.xious brain.effects that may occur in.in.ividuals who use psychostimulan.s for recreation.l an./or therapeutic purposes.

关键词： 3,4-methylen.dioxymethamphetamin. amphetamin. caffein. cell cultures cocain. methamphetamin. methylphen.date n.urotoxicity n.cotin.

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Characterization.of Arroyo Verde Epithermal Deposit:Paragen.sis,Min.ral Geochemistry,Geochron.logy an. Fluid In.lusion. in.Lower Chon.Aike Volcan.sm,Argen.in.

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Journ.l of Earth Scien.e 2024年第1期35卷 62-84页

作者： Cecilia Pavón.Pivetta Leon.rdo Ben.din. Paulo Marcos Ma.Agustin. Cócola Mercedes Virgin.a Barros Dan.el Gregori Leon.rdo Strazzere An.erson.costa dos San.os Mauro C.Geraldes In.tituto Geologico del Sur(In.EOSUR) Universidad Nacional del Sur(UNS)-Consejo Nacional de Investigaciones Cientificas y Tecnicas(CONICET)Bahia Blanca 8000Argentina Dpto.de Geologia Universidad Nacional del Sur(UNS)Bahia Blanca 8000Argentina Un.versidad n.cion.l de Rio n.gro Instituto de Investigacion en Paleobiologia y GeologiaGeneral Roca 8332Argentina Un.versidade do Estado do Rio de Jan.iro Faculdade de GeologiaDepartamento de Mineralogia e Petrologia igneaRiodeJaneiro20559-900Brazil Geobiotec Departamento de GeocienciasUniversidade de AveiroAveiro 3800-002Portuga

Arroyo Verde epithermal deposit,in.the n.rth Patagon.a region.of Argen.in.,is located within.the Lower Chon.Aike volcan.sm an. is developed between.192.6±2.5 Ma(min.ralization.host rock)an. 189.5±2.6 Ma(overlyin. lava).Marifil volcan.c complex is the host rock for these vein.,vein.ets an. *** particular small deposit has developed low to in.ermediate sulphidation.characteristics,with gan.ue min.ral textures associated with several ore *** probe microan.lysis determin.s electrum,silver min.rals such as acan.hite,an. tetrahedrite,related Ag-Cu min.rals like jalpaite,mckin.tryite,stromeyerite,an. base metals like chalcopyrite,sphalerite,galen. an. *** in.lusion. in.quartz of two out of five even.s in.icate that these Low Jurassic vein. were formed due to subtle boilin. an. dilution.mechan.sms an. by low-salin.ty(3.4 wt.%to 6.7 wt.%n.Cl Eq)magmatic-hydrothermal fluid at 225 to 310℃.The fluid in.lusion.measuremen.s that in.icate boilin.(Even. 3)were plotted,an. based on.this data,we in.erpret that the Arroyo Verde deposit has been.eroded between.550 an. 700 *** particular character has n.t been.previously recorded for other sectors of the eastern.n.rth Patagon.an.region.

关键词： epithermal deposit Ag min.rals min.ral geochemistry fluid in.lusion. Chon.Aike geochron.logy

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Cogn.tive fun.tion.amon. military veteran. with STEM occupation.

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Military Medical Research 2024年第2期11卷 308-310页

作者： justin T.McDan.el Kevin.n.Hascup Erin.R.Hascup Ugochukwu G.Ezigbo Aman.a M.Weidhun.r Harvey Hen.on.David L.Albright Dale an. Deborah Smith Cen.er for Alzheimer's Research an. trEatmen.(CARE) Southern Illinois University School of MedicineSpringfieldIL 62794USA STEM Education.Research Cen.er Southern Illinois UniversityCarbondaleIL 62901USA Departmen. of Political Scien.e The University of AlabamaTuscaloosaAL 35487USA

Dear Editor,There is limited research on.the relation.hip between.scien.e,techn.logy,en.in.erin.,an. mathematics(STEM)occupation.l history an. cogn.tive fun.tion.in.later life,especially amon. military veteran.,who may be at greater risk for later-life cogn.tive *** study examin.s a n.tion.lly represen.ative sample of military veteran. to address this gap in.kn.wledge.

关键词： Alzheimer's disease Veteran. Scien.e techn.logy en.in.erin. an. mathematics(STEM) An.mal fluen.y test Demen.ia

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In.lammatory markers,oxidative stress,an. mitochon.rial dyn.mics:Repercussion. on.coron.ry artery disease in.diabetes

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World Journ.l of Diabetes 2024年第9期15卷 1853-1857页

作者： JoséCarlos Tatmatsu-Rocha Luan.San.os Men.es-costa College of Medicin. Postgraduate Program in Physiotherapy and FunctionalityFederal University of Ceará-UFCFortaleza 60430-450CearáBrazil Physical Therapy Federal University of CearáFortaleza 60000-000CearáBrazil

In.lammatory markers an. mediators that affect the developmen. of cardiovascular diseases have been.the focus of recen. scien.ific ***,the purpose of this editorial is to promote a critical debate about the article titled“n.-carboxymethyl-lysin. an. in.lammatory cytokin.s,markers,an. mediators of coron.ry artery disease progression.in.diabetes”,published in.the World Journ.l of Diabetes in.*** work directs us to reflect on.the role of advan.ed glycation.en. products,which are pro-in.lammatory products arisin. from the metabolism of fatty acids an. sugars whose main.marker in.tissues is n.-carboxymethyllysin.(n.L).Recen. studies have lin.ed high levels of pro-in.lammatory agen.s with the developmen. of coron.ry artery disease(CAD),especially tumor n.crosis factor alpha,in.erleukin.,an. C-reactive *** in.lammatory agen.s in.rease the production.of reactive oxygen.species(ROS),of which people with diabetes are kn.wn.to have an.in.reased *** in.rease in.ROS promotes lipid peroxidation.which causes damage to myocytes,promotin. myocardial ***,oxidative stress in.uces the bin.in. of n.L to its receptor RAGE,which in.turn.activates the n.clear factor-kB,an. con.equen.ly,in.lammatory *** in.lammatory cytokin.s in.uce en.othelial dysfun.tion.with in.reased expression.of adhesion.molecules,chan.es in.en.othelial permeability an. chan.es in.the expression.of n.tric *** this sen.e,the therapeutic use of mon.clon.l an.ibodies(in.lammatory reducers such as statin. an. sodium-glucose tran.port in.ibitors)has demon.trated positive results in.the regression.of atherogen.c plaques an. con.equen.ly *** the other han.,man. studies have demon.trated a relation.hip between.mitochon.rial dyn.mics,diabetes,an. cardiovascular *** lin. occurs sin.e ROS have their origin.in.the imbalan.e in.glucose metabolism that occurs in.the mitochon.rial matrix,an. this imbalan.e can.have its origin.in.in.dequate diet as well as

关键词： Mitochon.rial dyn.mics Diabetes Oxidative stress Coron.ry artery disease n.-carboxymethyl-lysin.

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The effect of abiotic stresses on.plan. C:n.P homeostasis an. their mitigation.by silicon

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The Crop Journ.l 2024年第2期12卷 340-353页

作者： Milton.Garcia costa Ren.to de Mello Prado Luiz Fabian. Palaretti Jon.s Pereira de Souza Jún.or Departmen. of Agricultural Production.Scien.e School of Agricultural and Veterinarian SciencesSão Paulo State UniversityJaboticabalBrazil

In.crop plan.s, various en.iron.en.al stresses affect the balan.e of carbon. n.trogen. an. phosphorus(C:n.P), leadin. to biochemical an. physiological alteration. an. reduction. in.yield. Silicon.Si) is a ben.ficial elemen. that alleviates plan. stress. Most studies in.olvin. silicon.have focused on.physiological respon.es, such as improvemen.s in.photosyn.hetic processes, water use efficien.y, an. an.ioxidan. defen.e systems. But recen. research suggests that stressed plan.s facin. either limited or excessive resources(water, light, n.trien.s, an. toxic elemen.s), strategically employ Si to main.ain.C:n.P homeostasis, thereby min.mizin. biomass losses. Un.erstan.in. the role of Si in.mitigatin. the impact of abiotic stresses on.plan.s by regulatin. C:n.P homeostasis holds great poten.ial for advan.in. sustain.ble agricultural practices in.crop production. This review presen.s recen. advan.es in.characterizin. the in.luen.e of en.iron.en.al stresses on.C:n.P homeostasis, as well as the role of Si in.preservin. C:n.P equilibrium an. atten.atin. biological damage associated with abiotic stress. It un.erscores the ben.ficial effects of Si in.sustain.n. C:n.P homeostasis an. in.reasin. yield via improved n.trition.l efficien.y an. stress mitigation.

关键词： n.trition.l stoichiometry Elemen.al stoichiometry Ben.ficial elemen. En.iron.en.al stresses n.trition.l efficien.y Carbon.use efficien.y Agricultural sustain.bility

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Does a large prostate size,small lesion.volume,or lon. n.edle distan.e from the probe to the lesion.reduce magn.tic reson.n.e imagin.–targeted can.er detection.

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Curren. Urology 2024年第2期18卷 144-147页

作者： Mark D.Bevill justin n.Drobish Kevin.J.Flyn. Maheen.Rajput Catherin. Metz Chad R.Tracy Paul T.Gellhaus Departmen. of Urology University of Iowa Carver College of MedicineIowa CityIAUSA Departmen. of Radiology University of Iowa Carver College of MedicineIowa CityIAUSA

Backgroun.:We aimed to evaluate whether large prostate size,small lesion.volume,or lon. lesion.distan.e from the ultrasoun. probe tip would decrease can.er detection.in.tran.rectal magn.tic reson.n.e imagin.(MRI)–targeted *** an. methods:Patien.s who un.erwen. MRI-targeted biopsy at our in.titution.between.May 2017 an. August 2019 were en.olled in.a prospective *** to 5 cores were obtain.d from≥2 prostate imagin. reportin. an. data system v2 lesion..A multivariable model was created that in.luded n.edle distan.e to the lesion.prostate specific an.igen.prostate imagin. reportin. an. data system,lesion.volume,an. prostate ***:A total of 377 patien.s with 533 lesion. un.erwen. a biopsy durin. the study period.A total of 233(44%)lesion. were positive for prostate can.er,an. 173(32%)lesion. had clin.cally sign.fican. prostate *** mean.n.edle distan.e to the lesion.was 11.7mm(in.erquartile ran.e,7.6–15.5mm).The likelihood of obtain.n. a positive core on.biopsy decreased as the distan.e fromthe ultrasoun. probe in.reased for all prostate can.ers an. clin.cally sign.fican. prostate can.er(p=0.018 an. p=0.004,respectively).Every 10mmfrom the rectum,there was an.8%–10%decrease in.the rate of can.er ***,as the prostate volume in.reased,the odds of obtain.n. a positive core also decreased(p=0.039).There was n. sign.fican. association.between.the lesion.size an. amoun. of can.er obtain.d on.***:Our data showed that tran.rectal MRI-targeted biopsy can.er detection.modestly decreased the lesion.from the ultrasoun. probe an. with a large prostate volume but could n.t prove that lesion.volume was a sign.fican. predictor of the amoun. of can.er detected.

关键词： Prostate can.er Biopsy Magn.tic reson.n.e imagin.

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Evaluation.of a hepatic biomarker of n.trition.l imbalan.e in.juven.le red drum(Sciaen.ps ocellatus) fed 60% soybean.meal-based diets usin. n.R-based metabolomics

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An.mal n.trition 2024年第1期16卷 45-61页

作者： Fabio Casu Aaron.M.Watson.justin Yost T.Gibson.Gaylord Dan.el W.Bearden.Michael R.Den.on Marin. Resources Research In.titute South Carolina Department of Natural Resources Bozeman.Fish Techn.logy Cen.er United States Fish and Wildlife Service Marin. Biochemical Scien.es Group Chemical Sciences Division National Institute of Standards and Technology Hollings Marine Laboratory

A 12-week feedin. trial with juven.le red drum(Sciaen.ps ocellatus) fed high-soybean.meal(SBM) diets was con.ucted to in.estigate a putative biomarker of n.trition.l imbalan.e, n.formimin.-L-glutamate(FIGLU). Three fishmeal-free, 60% SBM pelleted diets(n.med B12, Fol, an. Met, respectively) were tested to evaluate the effects on.growth performan.e an. tissue metabolite profiles of supplemen.ation.of vitamin.B12(0.012 mg/kg), folate(10 mg/kg), methion.n.(1 g/kg) respectively, above basal supplemen.ation.levels. A fourth SBM-based diet(n.med B12/Fol/Met) was formulated with a combin.tion.of B12, folate, an. methion.n. to attain.the above-men.ion.d target con.en.ration.. A fifth 60% SBM diet(n.med FWS) with methion.n. supplemen.ation.1 g/kg above basal supplemen.ation.levels), en.iched with taurin., lysin. an. threon.n. as well as min.rals, was also tested. This diet con.ain.d formulation.targets an. additives which have allowed for replacin. fishmeal with plan. protein. in.rain.ow trout feeds. Con.rol diets in.luded a fishmeal-based diet(n.med FM), an.un.upplemen.ed basal 60% SBM diet(n.med SBM60), an. a “n.tural” diet(n.med n. made up of equal parts of fish(cigar min.ows), squid an. shrimp as a positive referen.e for growth performan.e. Formulated feeds con.ain.d approximately 37% total crude protein. approximately 14% total crude lipid an. were en.rgetically balan.ed. Stan.ard growth performan.e metrics were measured, an. tissues(liver, muscle) were collected at week 12 to evaluate diet-in.uced metabolic chan.es usin. n.clear magn.tic reson.n.e(n.R)-based *** results show that the FWS diet outperformed all other SBM diets an. the FM diet un.er all performan.e metrics(Pn.t detected in.fish fed the n.diet but was detected in.those fed the SBM diets an. the FM diet. Fish fed the FWS diet an. the Met diet showed lower hepatic levels of FIGLU compared with the other SBM-based diets(Pn. that amon. the differen. supplemen.atio

关键词： Aquaculture Metabolomics n.clear magn.tic reson.n.e Red drum Soybean.meal n.Formimin.-L-glutamate

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