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Dysregulated expression of T cell Immunoglobulin and Mucin Domain 3 is associated with the brain injury and the outcome of patients with spontaneous intracerebral hemorrhage

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Dysregulated expression of T cell Immunoglobulin and Mucin D...

机械合金化联合真空热压烧结工艺制备CoCrFeNi高熵合金的力学性能和耐腐蚀性能

第八届全国免疫学学术大会

作者： Xiao Liu junyu You Lifen Gao Xiaohong Liang Chunhong ma 山东大学医学院免疫学研究所

研究背景:Spontaneous intracerebral hemorrhage(ICH) is the most devastating type of *** response contributes to the ensuing brain injury.T cell Immunoglobulin and Mucin Domain 3(Tim-3), expressed on a variety of adaptive and innate immune cells, is one of well-known immunoregulatory molecules and involved in the pathogenesis of many inflammatory diseases.目的:To investigated the alteration of Tim-3 expression in ICH patients and analyzed its association with the brain injury and the outcome of these patients.方法:Blood samples were routinely taken from the antecubital vein from normal volunteers and ICH patients within 24 h since ischemic stroke *** cytometry was used to determine Tim-3 expression onperipheral blood *** prognosis of ICH patients was estimated using Glasgow Outcome scale(GOS) at 30 days.A good functional outcome was defined as GOS score 3 to 5 and a poor functional outcome was defined as GOS score 1 to *** correlation analysis was performed between the Tim-3 expression and blood glucose and lymphocyte counts.结果:Flow cytometry assay disclosed that Tim-3 expressions on CD3+ T cells and CD8+ T cells in ICH patients are significantly lower than those of healthy control, while Tim-3 expressions on CD14+ monocytes and CD16CD56+ NK cells are higher than those of healthy *** statistical analysis showed that only Tim-3 expression on CD8+ T cells was associated with the disease severity and the outcome of the ICH ***, there was no significant relationship between Tim-3 expression and blood glucose concentration.结论:Altered expression of Tim-3 might play an important role in the pathogenesis of *** studies will provide a novel candidate molecule for prognosis evaluation and clinical treatment of ICH patients.

关键词： Intracerebral hemorrhage(ICH) T cell Immunoglobulin and Mucin Domain 3(Tim-3) Glasgow coma scale(GCS) Glasgow Outcome scale(GOS) blood glucose

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稀有金属材料与工程 2022年第9期51卷 3182-3188页

作者：杨宇陈俊宇马通祥扈玫珑重庆大学材料科学与工程学院重庆400044 重庆大学钒钛冶金及新材料重庆市重点实验室重庆400044

采用机械合金化和真空热压烧结工艺制备了CoCrFeNi高熵合金。采用X射线衍射仪、扫描电子显微镜、电感耦合等离子体发射光谱和光学显微镜对产物的相结构和微观结构进行了表征,并采用万能试验机、维氏硬度计和电化学工作站对其力学性能和... 详细信息

采用机械合金化和真空热压烧结工艺制备了CoCrFeNi高熵合金。采用X射线衍射仪、扫描电子显微镜、电感耦合等离子体发射光谱和光学显微镜对产物的相结构和微观结构进行了表征,并采用万能试验机、维氏硬度计和电化学工作站对其力学性能和耐腐蚀性能进行了研究。结果表明:与电化学还原联合热压烧结工艺以及电弧熔炼法制备的CoCrFeNi高熵合金性能相比,机械合金化联合真空热压烧结工艺制备的CoCrFeNi高熵合金具有良好的抗拉伸强度和断裂伸长率,其合金硬度是电弧熔炼法制备合金的2倍,在0.5 mol/L H_(2)SO_(4)、1 mol/L KOH和3.5%(质量分数)Na Cl水溶液中,该合金具有与304不锈钢及电化学还原联合热压烧结工艺或电弧熔炼法制备合金相当的耐腐蚀性能。

关键词：熵值合金机械合金化真空热压烧结力学性能耐腐蚀性能

Pervasiveness of Predatory Spiders in Bt Cotton and Survivorship of Pardosa astrigera on Raised Live Insects

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Pervasiveness of Predatory Spiders in Bt Cotton and Survivor...

沙盘游戏疗法对青少年抑郁障碍患者的干预效果评价

中国农学会棉花分会2018年年会

作者： Muhammad Nasir Zhang Shuai Luo junyu ma Chao Zhao Chenchen Cui Jinjie Institute of Cotton Research (ICR) Chinese Academy of Agricultral Sciences (CAAS)

Spiders are one of the most universal group of predatory organisms belonging to animal *** regarding to identification of spiders prevailing in genetically modified crop(Bt-cotton) and rearing of Pardosa astrigera(wolf spider),on live insects,given as diet under laboratory conditions,were carried out at Institute of Cotton Research(ICR) of CAAS,Anyang,Henan.A number of spiders were collected during September-October,2017,using beat bucket method and vial tapping/jarring from 20 points,each with 1 m,5 in one acre(about 4 047 m),4 corners sides(5 meter inside the crop) and one central point of each acre) following x-manner within Bt cotton covering an area of 4 acres,East farms,ICR,*** of each collected spider was carried out,based on morphometric characteristics of various body parts according to following the information and different scientific reports from China and World Spiders catalog *** regarding survival of wolf spider under laboratory conditions were conducted for 8 *** various reared insects,Drosophila melanogaster,fruit fly(FF);Myzus persicae,green peach aphid(GPA) and Musca domestica,house fly(HF) were given in diet separately and in a specific combination(1 time FF,2 time GPA and 3 time HF) on every second day along with water soaked cotton swab during the whole study period.A total number of 172 spiders were identified from the current collection with 10 different spider’s species(Oxyopes sertatus,Peucetia latikae,Hylyphantes graminicola,Pardosa astrigera,Steatoda triangulosa,Misumenops tricuspidatus,Xysticus ephippiatus,Neoscona theisi,Plexippus setipes and Cheiracanthium uncinatum) belong to 8 different families(Oxyopidae,Linyphiidae,Lycosidae,Theridiidae,Thomisidae,Araneidae,Salticidae and Eutichuridae).Percentage prevalence of each spider’s family was lingered between 1.74% and 22.09%.maximum prevalence(22.09%) was of Oxyopidae(n=38) followed by 21.51% Linyphiidae(n=37),17.44% Lycosidae(n=30),15.17% Th

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临床心身疾病杂志 2024年第5期30卷 77-80页

作者：刘静韩玉霞陈俊宇何艳平杨玥朱利红马雁冰崔永霞连卓洛阳市第五人民医院河南洛阳471000

目的分析沙盘游戏疗法对青少年抑郁障碍患者的干预效果。方法将186例青少年抑郁障碍患者随机分为研究组(92例)和对照组(94例)。两组患者均遵循标准治疗流程接受盐酸舍曲林片治疗,研究组患者在此基础上联合沙盘游戏疗法治疗。干预前及干... 详细信息

目的分析沙盘游戏疗法对青少年抑郁障碍患者的干预效果。方法将186例青少年抑郁障碍患者随机分为研究组(92例)和对照组(94例)。两组患者均遵循标准治疗流程接受盐酸舍曲林片治疗,研究组患者在此基础上联合沙盘游戏疗法治疗。干预前及干预4周、8周和12周,采用抑郁自评量表(SDS)、焦虑自评量表(SAS)和个体和社会功能量表(PSP)对两组患者进行疗效评估。结果干预4、8、12周,两组患者SDS、SAS评分均较干预前降低,且研究组低于对照组(P<0.05或0.01);干预8、12周,两组患者PSP评分均较干预前升高,干预4、8、12周研究组患者PSP评分均高于对照组(P<0.05或0.01)。结论沙盘游戏疗法可有效缓解青少年抑郁障碍患者的相关症状,改善个体和社会功能。

关键词：青少年抑郁障碍沙盘游戏疗法

胶东西南部三合山岩体岩石成因和构造背景:年代学、地球化学及Sr-Nd-Pb-Hf同位素约束

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中国地质 2024年第4期51卷 1387-1410页

作者：邹占春刘俊玉陈建李景波丁正江孙丽莎李双飞唐名鹰张蕾王欣然山东省第八地质矿产勘查院山东日照276800 山东省地矿局有色金属矿找矿与资源评价重点实验室山东日照276800 山东理工大学资源与环境工程学院山东淄博255000 临沂市自然资源和规划局山东临沂276000 山东省第六地质矿产勘查院山东威海264209 山东省深部金矿探测大数据应用开发工程实验室山东威海264209 山东省物化探勘查院山东济南250013

【研究目的】胶东地区是中国最大的金矿矿集区,也是山东省最为重要的铜钼多金属矿成矿区。加强中生代花岗岩的岩相学、岩石地球化学和年代学等方面的研究,有利于进一步促进该区金及多金属矿的找矿工作。【研究方法】本文以胶东半岛西南... 详细信息

【研究目的】胶东地区是中国最大的金矿矿集区,也是山东省最为重要的铜钼多金属矿成矿区。加强中生代花岗岩的岩相学、岩石地球化学和年代学等方面的研究,有利于进一步促进该区金及多金属矿的找矿工作。【研究方法】本文以胶东半岛西南部三合山岩体中细粒二长花岗岩和花岗斑岩为研究对象,开展系统的岩相学、LA-ICP-MS锆石U-Pb年代学、主微量元素地球化学、全岩Sr-Nd-Pb同位素及锆石Lu-Hf同位素研究,旨在探讨其岩石成因、岩浆源区性质和构造背景。【研究结果】LA-ICP-MS锆石U-Pb定年结果表明,中细粒二长花岗岩的成岩年龄为(115.42±0.27)ma,花岗斑岩的形成年龄为(115.21±0.25)ma,形成时代均属中生代早白垩晚期;岩石地球化学特征表明,中细粒二长花岗岩和花岗斑岩均属高钾钙碱性I型花岗质岩石,LREE较HREE分馏明显,具弱Ce负异常和明显Eu中等负异常,富集Rb、K、Zr和Hf,亏损Sr、Ba、Nb、P、Ti;全岩Sr-Nd-Pb及锆石Hf同位素分析结果表明,三合山岩体起源于重熔的下地壳,并受到了幔源物质的混染。【结论】三合山岩体形成于早白垩世太平洋板块相对欧亚板块俯冲导致的陆内伸展背景下,为中国东部岩石圈减薄过程中壳幔相互作用的产物。

关键词：地球化学地质年代学 Sr-Nd-Pb-Hf同位素地质调查工程胶东山东省

Photovoltaic-powered supercapacitors for driving overall water splitting:A dual-modulated 3D architecture

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Carbon Energy 2022年第6期4卷 1262-1273页

作者： Zixu Sun Lijuan Sun See Wee Koh junyu Ge Jipeng Fei Mengqi Yao Wei Hong Shude Liu Yusuke Yamauchi Hong Li Key Lab for Special Functional materials of Ministry of Education National and Local Joint Engineering Research Center for High-Efficiency Display and Lighting TechnologyCollaborative Innovation Center of Nano Functional Materials and ApplicationsSchool of Materials Science and EngineeringHenan UniversityKaifengPeople's Republic of China School of Mechanical and Aerospace Engineering Nanyang Technological UniversitySingaporeSingapore School of Electronic and Information Zhongyuan University of TechnologyZhengzhouPeople's Republic of China JST-ERATO Yamauchi material Space-Tectonics Project National Institute for Materials Science(NIMS)TsukubaIbarakiJapan Australian Institute for Bioengineering and Nanotechnology(AIBN) The University of QueenslandBrisbaneQueenslandAustralia

Due to the growing demand for clean and renewable hydrogen fuel,there has been a surge of interest in electrocatalytic water-splitting devices driven by renewable energy ***,the feasibility of self-driven water splitting is limited by inefficient connections between functional modules,lack of highly active and stable electrocatalysts,and intermittent and unpredictable renewable energy ***,we construct a dualmodulated three-dimensional(3D)NiCo_(2)O_(4)@NiCo_(2)S_(4)(denoted as NCONCS)heterostructure deposited on nickel foam as a multifunctional electrode for electrocatalytic water splitting driven by photovoltaic-powered *** to a stable 3D architecture configuration,abundant active sites,efficient charge transfer,and tuned interface properties,the NCONCS delivers a high specific capacity and rate performance for supercapacitors.A twoelectrode electrolyzer assembled with the NCONCS as both the anode and the cathode only requires a low cell voltage of 1.47 V to achieve a current density of 10 ma cm^(−2) in alkaline electrolyte,which outperforms the state-of-the-art bifunctional *** calculations suggest that the generated heterointerfaces in NCONCS improve the surface binding capability of reaction intermediates while regulating the local electronic structures,which thus accelerates the reaction kinetics of water *** a proof of concept,an integrated configuration comprising a two-electrode electrolyzer driven by two series-connected supercapacitors charged by a solar cell delivers a high product yield with superior durability.

关键词： hybrid energy systems interface engineering morphology control solar-to-hydrogen trifunctional electrode

亚临界区圆柱绕流相干结构壁面模化混合RANS/LES模型

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物理学报 2024年第5期73卷 190-216页

作者：季梦尤云祥韩盼盼邱小平马乔吴凯健上海交通大学海洋工程国家重点实验室上海200240 上海君昱信息科技有限公司上海201800 上海交通大学三亚崖州湾深海科技研究院三亚572000

本文发展了一种具有壁面模化大涡模拟能力的雷诺平均纳维-斯托克斯(RANS)和大涡模拟(LES)方法的混合模型(简称WM-HRL模型),致力于对亚临界区雷诺数钝体绕流相干结构这类复杂流动现象进行高置信度的CFD解析模拟研究.该方法通过一个仅与... 详细信息

本文发展了一种具有壁面模化大涡模拟能力的雷诺平均纳维-斯托克斯(RANS)和大涡模拟(LES)方法的混合模型(简称WM-HRL模型),致力于对亚临界区雷诺数钝体绕流相干结构这类复杂流动现象进行高置信度的CFD解析模拟研究.该方法通过一个仅与当地网格空间分布尺寸有关的湍动能解析度指标参数rk即可实现从RANS到LES的无缝快速转换,并且RANS/LES混合转换区的边界位置及其各个分区(包括RANS区、LES区及RANS/LES混合转换区)对湍动能的解析能力均可通过两个指标参数nrk1-Q和nrk2-Q准则进行预先设定.通过对雷诺数Re=3900下圆柱绕流场的系列数值模拟研究,获得了能够高置信度解析并捕捉其绕流场中三维时空瞬态发展相干结构特性的湍动能解析度指标参数nrk1-Q和nrk2-Q准则的组合条件.研究表明,该WM-HRL模型不仅能够准确获取圆柱绕流场中剪切层小尺度K-H不稳定性结构的精细谱结构,而且在同一套网格系统下通过变化湍动能解析度指标参数nrk2-Q和nrk1-Q准则的组合条件,还可以精细解析圆柱绕流场中两类不同回流区的长度结构特征,及其对应的圆柱尾部近壁面处V和U形两个平均流向速度剖面的分支结构特性.

关键词：圆柱绕流相干结构 Kelvin-Helmholtz不稳定性混合RANS/LES模型

Anion-regulation engineering toward Cu/In/MOF bimetallic electrocatalysts for selective electrochemical reduction of CO_(2) to CO/formate

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materials Reports(Energy) 2022年第3期2卷 65-70页

作者： Bingqing Xu Israr masood Ul Hasan Luwei Peng junyu Liu Nengneng Xu Mengyang Fan Nabeel Khan Niazi Jinli Qiao State Key Laboratory for Modification of Chemical Fibers and Polymer materials College of Environmental Science and EngineeringDonghua UniversityShanghai201620China Shanghai Institute of Pollution Control and Ecological Security Shanghai200092China Institute of Soil and Environmental Sciences University of Agriculture FaisalabadFaisalabad38040Pakistan Department of Mechanical and Industrial Engineering University of TorontoTorontoOntarioM5S 3G8Canada

The conversion of carbon dioxide(CO_(2))into high-value added energy fuels and chemicals(CO,formate,C_(2)H_(4),etc.)through electrochemical reduction(eCO_(2)R)is a promising avenue to sustainable ***,low selectivity,barren activity and poor stability of the electrodes hinder the large-scale application of eCO_(2)***,we reported a copper-indium-organic-framework(CuIn-MOF)based high-performance catalyst for eCO_(2)***-trochemical measurement results reveal that CuIn-MOF exhibits high Faradaic efficiency(FE)of CO and formate(300 mV,FE_(CO)=78.6%at-0.86 V ***,FE_(HCOO^(-))=48.4%at-1.16 V ***,respectively)in a broad range of current density(20.1–88.4 ma cm^(-2))with long-term stability(6 h)for eCO_(2)R in 0.5 M KHCO_(3)electrolyte ***,through anion-regulation engineering,SO_(4)^(2-)anion precursor is more beneficial for the formic acid generation than NO_(3)^(-)anion precursor;while for SO_(4)^(2-)anion precursor,Cu plays a positive regulating role in eCO_(2)R to CO compared to ***,the high performance in a home-made eCO_(2)R reactor derives benefit from enhanced intrinsic activity and charge re-distribution can be attributed to the formation of In-doped Cu layer.

关键词： CuIn-MOF based Catalyst Anion-regulation engineering CO_(2)electroreduction CO/Formate production CO_(2)electrolyzer

A 9.5-kb deletion in the 1st intron of OsmaDS51 enhances temperature sensitivity in rice

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