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Isolated vaginal metastasis from stage Ⅰ colon cancer: A case report

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World Journal of Clinical Cases 2020年第3期8卷 527-534页

作者： soon Keun Kwon Chang Sik Yu Shin-Wha lee Jihun Kim Inho Song Jong Lyul lee Chan Wook Kim Yong Sik Yoon In Ja Park Seok-Byung Lim Jin Cheon Kim Division of Colon and Rectal Surgery Department of SurgeryUniversity of Ulsan College of MedicineAsan Medical CenterSeoul 05505South Korea Department of Obstetrics and Gynecology University of Ulsan College of MedicineAsan Medical CenterSeoul 05505South Korea Department of Pathology University of Ulsan College of MedicineAsan Medical CenterSeoul 05505South Korea

BACKGROUND Distant metastasis occasionally occurs in patients who have been diagnosed with colorectal cancer(CRC), but it occurs in a few patients with stage I CRC. The vagina as a metastasis site has also been reported, albeit rarely. Most reported cases of vaginal metastasis(VM) report their origin from advanced CRC. We encountered a patient who was diagnosed with isolated VM originating from stage I colon cancer(T2N0) and herein present the case of this *** SUMMARY A 63-year-old woman visited the outpatient clinic because of a positive result from a stool occult blood test. She underwent laparoscopic anterior resection and was pathologically diagnosed with stage I(T2N0) sigmoid colon cancer. Neither lymphovascular invasion nor perineural invasion was observed. Ten months following the surgery, isolated vaginal metastases were detected on gynecologic examination. The examination was performed due to vaginal spotting. A transvaginal wide excision was performed, and no other adjuvant treatment was provided after discussion with a multidisciplinary team and the ***, a new VM was discovered after 33 mo. An additional transvaginal excision was performed. To date, there has been no evidence of further disease progression. From the time of diagnosis of VM, the patient’s overall survival has been 54 *** VM can occur as a result of early-stage colorectal cancer. Surgeons should consider the possibility of VM following complaints of gynecologic symptoms following surgery.

关键词： Colorectal cancer Stage I Vaginal metastasis Isolated metastasis Case report

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大米饮料制备工艺研究

食品与机械 2005年第6期21卷 68-70,78页

作者：金海珠叶向库付学军杨建荣赵玉平郑舜泽朴亮均烟台大学食品科学与工程研究所山东烟台264005 木浦大学校食品产业技术研究中心国家重点实验室

利用糙米和精米经烘炒、生物酶解、过滤、罐装、包装等工序制造色泽清亮、香气宜人、保留糙米和精米原有成分的甘甜可口的大米饮料。对烘烤时间及水解条件等关键工序作了较为系统的研究,大米最佳烘烤条件:白米190℃、20min效果较好,糙米... 详细信息

利用糙米和精米经烘炒、生物酶解、过滤、罐装、包装等工序制造色泽清亮、香气宜人、保留糙米和精米原有成分的甘甜可口的大米饮料。对烘烤时间及水解条件等关键工序作了较为系统的研究,大米最佳烘烤条件:白米190℃、20min效果较好,糙米180℃、20min。最佳水解条件为蛋白水解酶2%,葡萄糖化酶125U/g,温度50℃,时间7h。

关键词：精米糙米饮料 α-淀粉酶葡萄糖化酶蛋白酶

腐植酸施用方法对绿豆产量及其构成因子的影响

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腐植酸 2016年第6期 36-40页

作者： Muhammad Waqas Bashir Ahmad Muhammad Arif Fazal Munsif Abdul Latif Khan Muhammad Amin Sang-Mo Kang Yoon-Ha Kim In-jung lee 刘雪娇茹雪峰高同国韩国庆北大学应用生物科学学院巴基斯坦开伯尔-普什图农业大学白沙瓦25000 巴基斯坦开伯尔-普什图农业推广学院布内尔999010 阿曼尼兹瓦大学生物科学与化学学院尼兹瓦518103 美国密苏里大学植物科学学院和大豆生物技术国家中心(NCSB) 哥伦比亚999076 河北农业大学生命科学学院保定071001 保定市清苑区第一中学保定071100

为了探索腐植酸(HA)的施用方法,在白沙瓦开伯尔-普什图省农业大学的农业研究农场内进行了完全随机区组设计试验,并设置3次重复。HA的施用方法分为浸种、叶片喷施和土壤施用3种。HA的施用方法对绿豆单株结荚数、每荚粒数、千粒重和籽粒... 详细信息

为了探索腐植酸(HA)的施用方法,在白沙瓦开伯尔-普什图省农业大学的农业研究农场内进行了完全随机区组设计试验,并设置3次重复。HA的施用方法分为浸种、叶片喷施和土壤施用3种。HA的施用方法对绿豆单株结荚数、每荚粒数、千粒重和籽粒产量具有显著影响,而对绿豆生物量影响不大。每公顷土地施用3 kg HA能显著提高绿豆结荚率、千粒重和产量;而土壤中加入1 kg/hm^2和2 kg/hm^2 HA,浓度为0、1%、2%的HA浸种和0.01%、0.05%、0.1%的HA叶面喷施3种方法所得到的结果在统计学上相似。由此得出结论:3种施用HA的方法均能显著提高绿豆产量及其构成因子。

关键词：绿豆腐植酸浸种叶面喷施土壤施用产量

新的心肌PET显像剂18F-FPTP的参数图形算法的比较

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中华核医学与分子影像杂志 2018年第2期38卷 151-151页

作者：唐军 Ji Who Kim Seongho Seo Hyeon Sik Kim Dong-Yeon Kim Ho-Young lee Keon Wook Kang Dong Soo lee Hee-Seung Bom jung-Joon Min Jae Sung lee 上海交通大学医学院附属苏州九龙医院核医学科 Department of Nuclear Medicine and Department of Biomedical Sciences Seoul National University Department of Cardiology Chonnam National University Hwasun Hospital

目的 (18F-氟戊基)三苯基季磷盐(18F-FPTP)是一种新的有应用前景的心肌PET显像剂,其在心肌细胞内积聚量多且肝脏清除快。该研究小组在小鼠体内做了18F-FPTP PET显像的代谢区室分析和两项线性分析,即用于生成参数图的线性最小二乘法（LL... 详细信息

目的 (18F-氟戊基)三苯基季磷盐(18F-FPTP)是一种新的有应用前景的心肌PET显像剂,其在心肌细胞内积聚量多且肝脏清除快。该研究小组在小鼠体内做了18F-FPTP PET显像的代谢区室分析和两项线性分析,即用于生成参数图的线性最小二乘法（LLS）和基函数法（BFM）分析。此外,还研究了动态分析的最小动态显像时间,并进行了计算机模拟。方法对心肌梗死（MI）小鼠模型（n=12）进行18F-FPTP动态PET显像（18 min）和CT显像。在左心室、正常心肌和梗死区勾画感兴趣区（ROI）。比较两室模型（速率常数k1和k2;2室2参数）和不可逆摄取的三室模型（速率常数k1-k3;3室3参数）的拟合优度,并进行部分容积和溢出校正（Vα和α=1-Va）。LLS和BFM用于基于ROI和基于体素的动力学参数估算,估算结果与相应代谢区室模型标准的基于ROI的非线性最小二乘法（NLS）结果进行比较。通过计算机模拟研究估算方法的统计学特点。结果 2室2参数模型最适于描述18F-FPTP的动力学表现。正常心肌的平均k1、k2和Va值分别是6.8ml·min-1·g-1、1.1/min和0.44,而梗死组织的分别是1.4 ml·min-1·g-1、1.1/min和0.32。动态显像10 min的数据即足够用于估算各项参数。LLS和BFM的估算结果与ROI水平的NLS的结果有很好的相关性（k1:1.22x-0.30,r2=0.90;y=1.26x+0.00,r2=0.92）。动态参数图形（αk1,k1,k2,Va）的局部分布具有生理相关性。在计算机模拟中,LLS和BFM比NLS的特征性更强。结论快速的动力学特征和心肌较高的特异性摄取使18F-FPTP能在显像开始的最初10 min动态显像内,利用2室2参数模型进行定量分析。LLS和BFM能在体素水平进行参数估算,这2种方法可用于定量评价18F-FPTP在心肌中的分布,进而研究其在不同条件、不同疾病模型和病种中进行心肌显像的表现。

关键词：定量参数图模拟心肌PET

Acupuncture for treating uremic pruritus in patients with end stage renal disease:a systematic review

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World Journal of Acupuncture-Moxibustion 2010年第4期20卷 42-42页

作者： Kun Hyung Kim Tae-Hun Kim jung Won Kang Myeong Soo lee Sun Mi Choi Edzard Ernst Acupuncture Moxibustion & Meridian Research Center Korea Institute of Oriental Medicine Daejeon Republic of Korea Peninsula Medical School Universities of Exeter & Plymouth

Objective This review aimed to systematically summarize and critically evaluate the clinical evidence for or against the effectiveness of acupuncture as a symptomatic therapy for uremic pruritus (UP) in end-stage renal disease (ESRD) patients. Materials and method: We searched 16 electronic databases from their inceptions to November 2009. All prospective clinical studies of needle acupuncture for uremic pruritus in hemodialysis patients with end-stage renal disease were included regardless of their design. Risk of bias of the included studies were assessed using the Cochrane criteria. Results Of 464 initially located articles, 458 studies were excluded. Three randomized controlled trials (RCTs), one non-randomized controlled trial (CCT) and two uncontrolled observational studies were included. In three RCTs, acupuncture was compared to sham-acupuncture (n=1), oral antihistamine plus topical ointment (n=1) and oral calcitriol (n=1). In one CCT, electroacupuncture (EA) was compared to superfi cial electrical stimulation. In two observational studies, EA (n=1) or manual acupuncture (n=1) were employed. Four of 6 included studies mentioned mild or no occurrence of adverse events. All of included trials reported benef icial effects of acupuncture. However, most of the studies showed high risk of bias, which leave their reports unconvincing. Conclusion The current evidence is insuffi cient to show that acupuncture is an effective treatment for uremic pruritus in patients with end-stage renal disease due to suboptimal quality and lack of methodological rigor of included studies. Future trials should overcome the limitations of the currently available evidence.

关键词：中医学针灸学针法灸法

Comparison of computed tomography findings between bacteremic and non-bacteremic acute pyelonephritis due to Escherichia coli

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World Journal of Radiology 2016年第4期8卷 403-409页

作者： Seon jung Oh Bo-Kyung Je Seung Hwa lee Won Seok Choi Doran Hong Sung-Bum Kim Department of Radiology Korea University Hospital Department of Internal Medicine Korea University Hospital Department of Internal Medicine B-um Hospital

AIM:To identify computed tomography(CT)findings that are associated with the presence of bacteremia in patients with acute pyelonephritis(APN)due to Escherichia coli(***).METHODS:The clinical data and contrast-enhanced CT findings of 128 patients who were diagnosed with APN due to *** and showed renal abnormality on contrast-enhanced CT between January 2003 and November 2013 were retrospectively *** patients were divided into two groups according to the presence of bacteremia:The bacteremia group and the non-bacteremia *** abnormality on contrast-enhanced CT were categorized into 5 renal and 4 extrarenal CT findings and compared between the two groups using the χ~2 test and multivariate logistic ***:Among the 128 patients,34 patients(26.6%)were classified into the bacteremia group and 94 patients(73.4%)into the non-bacteremia *** was no statistically significant difference in gender between the two groups(P = 0.09),but the age of thepatients in the bacteremia group was higher than that of the patients in the non-bacteremia group(P < 0.01).Compared to the non-bacteremia group,1 renal CT finding such as urothelial thickening and 3 extrarenal CT findings such as diffuse peritoneal thickening,cystitis and pulmonary congestion were more frequently observed in the bacteremia group with statistical *** logistic regression analysis revealed that CT findings,including urothelial thickening,diffuse peritoneal thickening,cystitis and pulmonary congestion were suggested as the predictive CT findings of bacteremic ***:On CT,urothelial thickening,diffuse peritoneal thickening,cystitis,and pulmonary congestion are more frequently observed in patients with bacteremic APN due to ***.

关键词： Escherichia coli Pyelonephritis Urinary tract infections Bacteremia Multidetector computed tomography

在有 ileoal 脂肪瘤的 64 岁的女性的小肠的摄取的 Laparoscopic 管理

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World Journal of Gastrointestinal Surgery 2012年第9期4卷 220-222页

作者： Yi-Chung Hou Po-Chu lee jung-jung Chang Department of General Surgery National Taiwan University Hospital Yun-Lin Branch Yun-Lin County 64041 Taiwan China

A 64-year-old female patient presented with upper ab-dominal pain and vomiting. Ultrasonography showed a hyperechoic mass in the right lower abdomen and computed tomography showed a low-density mass with intestinal invagination. An emergency laparo-scopic right-hemicolectomy was performed, and the resected specimen was found to contain three tumors, which were identified histopathologically as intestinal lipomas. Adult intussusception is relatively rare and difficult to be diagnosed, since most symptoms of adult intussusception are nonspecific. We report our clinical experience of the diagnosis and emergent laparoscopic surgery for an adult patient with intussusception.

关键词： Adult Ileus Intussusception Intestinal lipomas Laparoscopy

肝转移癌射频消融治疗方案制定--超声造影的应用价值

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介入放射学杂志 2014年第6期23卷 487-490页

作者：吴薇吴洁武金玉严昆杨薇李荣杰张仲一陈敏华北京大学肿瘤医院暨北京市肿瘤防治研究所超声科恶性肿瘤发病机制及转化研究教育部重点实验室 100142 哈尔滨市第一医院超声科

目的探讨超声造影(CEUS)在肝转移癌经皮射频消融(RFA)治疗前的应用价值。方法2001年7月—2012年12月期间经皮RFA治疗的肝转移癌共267例485灶为本研究对象。其中180例251灶RFA治疗前行CEUS检查并确定RFA治疗方案(CEUS组),另87例234灶为RF... 详细信息

目的探讨超声造影(CEUS)在肝转移癌经皮射频消融(RFA)治疗前的应用价值。方法2001年7月—2012年12月期间经皮RFA治疗的肝转移癌共267例485灶为本研究对象。其中180例251灶RFA治疗前行CEUS检查并确定RFA治疗方案(CEUS组),另87例234灶为RFA治疗前未行CEUS检查(对照组)。两组病例的各项临床资料差异均无统计学意义(P0.05)。局部复发率CEUS组低于对照组,分别为12.4%(31/251)、19.7%(46/234)(P0.05)。结论肝转移癌经皮RFA治疗前行CEUS检查有助于准确判断病灶大小及数目,制订有效治疗方案,从而提高肿瘤早期灭活率、降低复发新生率。

关键词：超声检查对比剂肝转移癌消融术

高抗性淀粉粳稻新品系稻米淀粉链长分布与主要品质特征差异

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中国农业科学 2009年第6期42卷 2237-2243页

作者：张淑梅张建明李丁鲁李茂柏王慧朴钟泽邹德堂上海市农业科学院作物育种栽培研究所东北农业大学农学院韩国农村振兴厅农业生命工学研究院安徽农业大学农学院

【目的】通过对水稻抗性淀粉性状的遗传研究,为高抗性淀粉水稻资源创新与育种提供理论和实践依据。【方法】以抗性淀粉含量有显著差异的粳稻品系为材料,比较分析高低抗性淀粉粳稻品系类型间的支链淀粉链长分布、稻米RVA谱特性值、膳食... 详细信息

【目的】通过对水稻抗性淀粉性状的遗传研究,为高抗性淀粉水稻资源创新与育种提供理论和实践依据。【方法】以抗性淀粉含量有显著差异的粳稻品系为材料,比较分析高低抗性淀粉粳稻品系类型间的支链淀粉链长分布、稻米RVA谱特性值、膳食纤维和直链淀粉含量等主要品质特性的差异及其相关性。【结果】高低抗性淀粉水稻品系间支链淀粉链长分布差异显著,高抗性淀粉水稻品系的支链淀粉中短链部分即聚合度为5～12所占的相对百分比率显著低于低抗性淀粉类型品系,而长链尤其是聚合度为13以上的长链比率明显高于低抗性淀粉类型品系。膳食纤维和直链淀粉含量,高抗性淀粉品系显著高于低抗性淀粉品系,最高黏度值、最终黏度值、热浆黏度值和崩解值等,高抗性淀粉品系均显著或极显著低于低抗性淀粉类型品系。抗性淀粉含量与支链淀粉短链聚合度(DP≤12)呈极显著负相关,但与支链淀粉的中长链聚合度(12

关键词：水稻抗性淀粉含量支链淀粉链长分布糊化特征