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Efficacy of adjuvant mitomycin-C and triamcinoloneimpregnated nasal packing for endoscopic dacryocystorhinostomy

International Journal of Ophthalmology(English edition) 2024年第3期17卷 480-484页

作者： Sang Yoon Kim Christopher B Chambers jung hyo ahn Department of Ophthalmology Pusan National University Yangsan HospitalPusan National University School of MedicineResearch Institute for Convergence of Biomedical Science and TechnologyYangsanGyeongnam 50612Republic of Korea Department of Ophthalmology Harborview Medical CenterUniversity of Washington MedicineSeattleWashington 98109USA

●AIM:To compare the success rate and complications of adjuvant use of mitomycin C and triamcinoloneimpregnated biodegradable nasal packing(TABP)in endoscopic dacryocystorhinostomy(DCR).And to evaluate the efficacy of combining intraoperative mitomycin C and TABP for endoscopic DCR.●METHODS:A total of 198 eyes of 148 patients who underwent endoscopic DCR for acquired nasolacrimal duct obstruction were retrospectively *** patients were randomly divided into three groups:Group A included patients treated without intraoperative mitomycin C but with TABP,Group B included patients treated without triamcinolone but with intraoperative mitomycin C and normal saline-impregnated nasal packing,and Group C included patients treated with intraoperative mitomycin C and TABP.●RESULTS:The results revealed no significant difference in the overall success rates between Groups A(86.8%)and B(89.2%;P=0.377).However,Group C(97.5%)showed a significantly higher overall success rate than Groups A and *** incidence of granulomas was significantly lower in group C(5%)than in Groups A(20.8%)and B(15.2%;P=0.009).Other complications,such as crust,synechiae,and revision surgery,did not differ significantly among the three groups.●CONCLUSION:The combination of intraoperative mitomycin C and TABP effectively prevents granulomas and enhances surgical success ***,there is no statistically significant difference observed between the use of mitomycin C or TABP alone.

关键词： dacryocystorhinostomy endoscopic mitomycin C triamcinolone biodegradable

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Periorbital necrotizing fasciitis accompanied by sinusitis and intracranial epidural abscess in an immunocompetent patient

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International Journal of Ophthalmology(English edition) 2022年第5期15卷 848-850页

作者： Su Youn Suh jung hyo ahn Department of Ophthalmology Research Institute for Convergence of Biomedical Science and TechnologyPusan National University Yangsan HospitalPusan National University School of MedicineYangsanGyeongnam 50612Republic of Korea

Dear Editor,We have presented the unusual case of periorbital necrotizing fasciitis(NF) coexisting with sinusitis and intracranial epidural abscess in a healthy young patient that was successfully managed with medical and surgical treatments. The authors obtained informed consent in person and adhered to the tenets of the Declaration of Helsinki.

关键词： patient sinusitis intracranial

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Scar sarcoidosis with systemic involvement after blepharoplasty

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International Journal of Ophthalmology(English edition) 2021年第8期14卷 1288-1290页

Dear Editor,Sarcoidosis is a systemic disorder of unknown etiology characterized by non-caseating epithelioid *** lungs,lymph nodes,liver,spleen,phalangeal cartilages,parotid glands,eyes,and skin are affected[1].

关键词： involvement spleen etiology

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A Cu-Pd alloy catalyst with partial phase separation for the electrochemical CO_(2) reduction reaction

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Journal of Energy Chemistry 2024年第6期93卷 8-15,I0001页

作者： Gyeong Ho Han jung Yong Seo Minji Kang Myung-gi Seo Youngheon Choi Soo Young Kim Sang Hyun ahn School of Chemical Engineering and Material Science Chung-Ang UniversitySeoul 06974Republic of Korea Lotte Chemical Institute of Technology Daejeon 34110Republic of Korea Department of Materials Science and Engineering Korea UniversitySeoul 02841Republic of Korea

Cu catalysts can convert CO_(2) through an electrochemical reduction reaction into a variety of useful carbon-based ***,this capability provides an obstacle to increasing the selectivity for a single ***,we report a simple fabrication method for a Cu-Pd alloy catalyst for use in a membrane electrode assembly(MEA)-based CO_(2) electrolyzer for the electrochemical CO_(2) reduction reaction(ECRR)with high selectivity for CO *** the composition of the Cu-Pd alloy catalyst was fabricated at 6:4,the selectivity for CO increased and the production of multi-carbon compounds and hydrogen is *** a Cu-Pd alloy catalyst with 6:4 ratio as the cathode of the MEAbased CO_(2) electrolyzer showed a CO faradaic efficiency of 92.8%at 2.4 V_(cell).We assumed that these results contributed from the crystal planes on the surface of the Cu-Pd *** phases of the Cu-Pd alloy catalyst were partially separated through annealing to fabricate a catalyst with high selectivity for CO at low voltage and C_(2)H_4 at high *** results of CO-stripping testing confirmed that when Cu partially separates from the lattice of the Cu-Pd alloy,the desorption of~*CO is suppressed,suggesting that C-C coupling reaction is favored.

关键词： Cu-Pd catalyst Electrodeposition Electrochemical carbon dioxide reduction Partial phase separation Membrane electrode assembly-based electrolyzer

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Structural and electrochemical stabilization enabling high-energy P3-type Cr-based layered oxide cathode for K-ion batteries

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Carbon Energy 2024年第5期6卷 81-93页

作者： Wonseok Ko Seokjin Lee Hyunyoung Park jungmin Kang Jinho ahn Yongseok Lee Gwangeon Oh jung-Keun Yoo Jang-Yeon Hwang Jongsoon Kim Department of Energy Science Sungkyunkwan UniversitySuwonRepublic of Korea SKKU Institute of Energy Science and Technology(SIEST) Sungkyunkwan UniversitySuwonRepublic of Korea Department of Energy Engineering Hanyang UniversitySeoulRepublic of Korea Carbon Composites Department Korea Institute of Materials Science(KIMS)ChangwonRepublic of Korea Department of Battery Engineering Hanyang UniversitySeoulRepublic of Korea

Layered-type transition metal(TM)oxides are considered as one of the most promising cathodes for K-ion batteries because of the large theoretical gravimetric capacity by low molar ***,they suffer from severe structural change by de/intercalation and diffusion of K^(+)ions with large ionic size,which results in not only much lower reversible capacity than the theoretical capacity but also poor power ***,it is important to enhance the structural stability of the layered-type TM oxides for outstanding electrochemical behaviors under the K-ion battery ***,it is investigated that the substitution of the appropriate Ti^(4+)contents enables a highly enlarged reversible capacity of P3-type KxCrO_(2) using combined studies of first-principles calculation and various *** the pristine P3-type KxCrO_(2) just exhibits the reversible capacity of∼120 mAh g^(−1) in the voltage range of 1.5-4.0 V(vs.K^(+)/K),the∼0.61 mol K^(+)corresponding to∼150 mAh g^(−1) can be reversible de/intercalated at the structure of P3-type K0.71[Cr_(0.75)Ti_(0.25)]O_(2) under the same ***,even at the high current density of 788 mA g^(−1),the specific capacity of P3-type K0.71[Cr_(0.75)Ti_(0.25)]O_(2) is∼120 mAh g^(−1),which is∼81 times larger than that of the pristine P3-type KxCrO_(2).It is believed that this research can provide an effective strategy to improve the electrochemical performances of the cathode materials suffered by severe structural change that occurred during charge/discharge under not only K-ion battery system but also other rechargeable battery systems.

关键词： cathodes first-principles calculations layered-type oxide materials potassium-ion batteries structural stabilization

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Artificial optoelectronic synapse based on spatiotemporal irradiation to source-sharing circuitry of synaptic phototransistors

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InfoMat 2024年第2期6卷 131-141页

作者： Seungho Song Changsoon Choi Jongtae ahn Je-Jun Lee Jisu Jang Byoung-Soo Yu jung Pyo Hong Yong-Sang Ryu Yong-Hoon Kim Do Kyung Hwang Center for Opto-Electronic Materials and Devices Post-Silicon Semiconductor InstituteKorea Institute of Science and Technology(KIST)SeoulRepublic of Korea School of Advanced Materials Science and Engineering Sungkyunkwan UniversitySuwonRepublic of Korea Center for Spintronics Post-Silicon Semiconductor InstituteKorea Institute of Science and Technology(KIST)SeoulRepublic of Korea Division of Nanoscience&Technology KIST SchoolUniversity of Science and Technology(UST)SeoulRepublic of Korea School of Biomedical Engineering Korea UniversitySeoulRepublic of Korea KU-KIST Graduate School of Converging Science and Technology Korea UniversitySeoulRepublic of Korea

To overcome the intrinsic inefficiency of the von Neumann architecture,neuromorphic devices that perform analog vector–matrix multiplication have been highlighted for achieving power-and time-efficient data *** particular,artificial synapses,of which conductance should be programmed to represent the synaptic weights of the artificial neural network,have been intensively researched to realize neuromorphic ***,inspired by excitatory and inhibitory synapses,we develop an artificial optoelectronic synapse that shows both potentiation and depression characteristics triggered only by optical *** design of the artificial optoelectronic synapse,in which excitatory and inhibitory synaptic phototransistors are serially connected,enables these characteristics by spatiotemporally irradiating the phototransistor channels with optical ***,a negative synaptic weight can be realized without the need for electronic components such as *** such attributes,the artificial optoelectronic synapse is demonstrated to classify three digits with a high recognition rate(98.3%)and perform image preprocessing via analog vector-matrix multiplication.

关键词： amorphous oxide semiconductor analog processing artificial synapse neuromorphic optoelectronics

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2.47 GPa grade ultra-strong 15Co-12Ni secondary hardening steel with superior ductility and fracture toughness

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Journal of Materials Science & Technology 2021年第7期66卷 36-45页

作者： Young-Kyun Kim Kyu-Sik Kim Young-Beum Song jung hyo Park Kee-ahn Lee Department of Materials Science and Engineering Inha UniversityIncheon22212Republic of Korea Agency for Defense Development(ADD) Yuseong-guDaegeon34186Republic of Korea

This study investigated the effect of multi-step heat treatment on the microstructure, mechanical properties and fracture behavior of thick 15 Co-12 Ni secondary hardening steel. As-quenched sample was found to have elongated prior austenite grain(PAG) and coarse lenticular martensitic structure. On the other hand, heat-treated sample was observed to have fine lenticular martensitic structure due to fine PAG size and a lot of nano-sized carbides. Also, after heat treatment, nano-scale reverted austenite film was formed at the martensite interfaces. The heat-treated sample showed 2.47 GPa superior tensile strength and superior elongation of about 12 %. The high strength was mainly due to fine block size and high number density of nano-sized carbides. The average value of plane strain fracture toughness(KIC) was 29.3 MPa m1/2, which indicated a good fracture toughness even with the high tensile strength. The tensile fracture surface was observed to have ductile fracture mode(cup-and-cone) and the formation of about ~1 μm ultra-fine dimples. In addition to this, nano-sized carbides were observed within the *** findings suggested that the nano-sized carbide had a positive effect not only on the strength but also on the ductility of the alloy. The fractured surface after toughness test, also showed ductile fracture mode with a lot of dimples. Based on the above results, correlation among microstructural evolution,deformation and fracture mechanisms along the heat-treatment was also discussed.

关键词： Ultra-high strength High Co-Ni secondary hardening steel Microstructure Tensile properties Fracture toughness Reverted austenite

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Bojungbangdocktang inhibits vascular endothelial growth factor induced angiogenesis via blocking the VEGF/VEGFR2 signaling pathway in human umbilical vein endothelial cells

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Chinese Science Bulletin 2009年第2期54卷 227-233页

作者： JANG Yu-Sung LEE Eun-Ok LEE hyo-jung LEE hyo-Jeong KIM Kwan-Hyun WON Sook-Hyun LEE Jae-Dong ahn Kwang Seok ahn Kyoo Seok KIM jung-hyo YU Young-Beob KIM Sung-Hoon College of Oriental Medicine Kyunghee University 1 Hoegidong Dongdaemungu Seou1130-701 Republic of Korea Chosun Nursing College 375 Seosuk-dong Dong-gu Gwangju 501-759 Korea Department of Herbal Pharmaceutical Korea Institute of Oriental Medicine Jeonmin dong Youseonggu Daejeon 305-811 Republic of Korea

Oriental herbal medicines have been widely used for the prevention or treatment of various diseases including cancer in Asia. However, to prove their chemo preventive efficacies in modern times, scientific evidence for those herbal medicines is required. Thus, in the present study, an effective herbal cocktail Bojungbangdocktang (BJBDT) was investigated to elucidate antiangiogenic mechanism in vitro and in vivo. BJBDT significantly inhibited vascular endothelial growth factor (VEGF) induced proliferation in HUVECs at nontoxic concentrations, despite weak cytotoxicity against human umbilical vein endothelial cells (HUVECs). BJBDT also significantly suppressed VEGF-induced migration and tube formation of HUVECs. Furthermore, BJBDT treatment resulted in pale color and low hemoglobin level in Matrigel plugs, as well as dark red color and high hemoglobin level in untreated control. Interestingly, BJBDT specifically inhibited the binding of VEGF to vascular endothelial growth factor receptor 2 (VEGFR2), but not VEGFR1. In addition, friedelin, formononetin, ginsenoside Rb1, naringin, atractyloside, diosgenin, and allantonin were identified from BJBDT by high-performance liquid chromatography (HPLC) analysis as a quality of control. Taken together, these results suggest that BJBDT is a potent angiogenesis inhibitor blocking the VEGF/VEGFR2 signaling pathway in HUVECs.

关键词：血管新技术人大动脉内皮细胞 HUVECs VEGFR2

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The Arabidopsis Floral Repressor BFT DelaysFlowering by Competing with FT for FD Bindingunder High Salinity

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Molecular Plant 2014年第2期7卷 377-387页

作者： Ryu, Jae Yong Lee, hyo-Jun Seo, Pil Joon jung, Jae-Hoon ahn, Ji Hoon Park, Chung-Mo Department of Chemistry Seoul National University Seoul 151-742 Korea Present address: Department of Chemistry Chonbuk National University Jeonju 561-756 Korea The Sainsbury Laboratory University of Cambridge Cambridge UK Creative Research Initiatives Division of Life Sciences Korea University Seoul 136-701 Korea PGBI Seoul National University Seoul 151-742 Korea

Soil salinity is one of the most serious agricultural problems that significantly reduce crop yields in the aridand semi-arid regions. It influences various phases of plant growth and developmental processes, such as seed germina-tion, leaf and stem growth, and reproductive propagation. Salt stress delays the onset of flowering in many plant spe-cies. We have previously reported that the Arabidopsis BROTHER OF FT AND TFL1 （BFT） acts as a floral repressor undersalt stress. However, the molecular mechanisms underlying the BFT function in the salt regulation of flowering inductionis unknown. In this work, we found that BFT delays flowering under high salinity by competing with FLOWERING LOCUST （FT） for binding to the FD transcription factor. The flowering time of FD-deficient fd-2 mutant was insensitive to highsalinity. BFT interacts with FD in the nucleus via the C-terminal domain of FD, which is also required for the interactionof FD with FT, and interferes with the FT-FD interaction. These observations indicate that BFT constitutes a distinct saltstress signaling pathway that modulates the function of the FT-FD module and possibly provides an adaptation strategythat fine-tunes photoperiodic flowering under high salinity.

关键词： Arabidopsis BFT FD flowering time FT salt stress

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Influence of process parameters on drilling characteristics of Al 1050 sheet with thickness of 0.2 mm using pulsed Nd:YAG laser

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中国有色金属学会会刊：英文版 2009年第B09期19卷 157-163页

作者： Dong-Gyu ahn Gwang-Won jung Department of Mechanical Engineering Chosun University

The object of this work is to investigate the influence of process parameters on drilling characteristics of an Al 1050 sheet with a thickness of 0.2 mm using a pulsed Nd:YAG laser through numerical analyses and experiments. By comparing the numerical analyses with the experiments, a proper numerical model was obtained. From the results of the numerical analyses and the experiments, the effects of process parameters on entrance diameters of drilled holes, shapes of the holes, taper angles of the holes and temperature distributions in the vicinity of the holes were examined quantitatively. In addition, the optimal drilling condition was estimated to improve the quality of the drilled holes.

关键词： YAG激光器工艺参数 Nd 脉冲井用厚度色基数值分析

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