检索结果-南通市图书馆

Stable immobilization of lithium polysulfides using three-dimensional ordered mesoporous Mn2O3 as the host material in lithium-sulfur batteries

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Carbon Energy 2024年第6期6卷 99-112页

作者： Sung Joon Park Yun Jeong Choi Hyun-seung kim Min Joo hong hongjun Chang Janghyuk Moon Young-jun kim junyoung Mun ki Jae kim Department of Energy Science Sungkyunkwan UniversitySuwonGyeonggi-doRepublic of Korea Department of Energy Engineering Konkuk UniversitySeoulRepublic of Korea Advanced Batteries Research Center Korea Electronic Technology InstituteSeongnamRepublic of Korea Department of Future Energy Engineering Sungkyunkwan UniversitySuwonRepublic of Korea Department of Energy Systems Engineering Chung-Ang UniversitySeoulRepublic of Korea SKKU Advanced Institute of Nanotechnology Sungkyunkwan UniversitySuwonGyeonggi-doRepublic of Korea SKKU Institute of Energy Science and Technology(SIEST) Sungkyunkwan UniversitySuwonRepublic of Korea School of Advanced Materials Science and Engineering Sungkyunkwan UniversitySuwonRepublic of Korea

Lithium-sulfur batteries(LSBs)have drawn significant attention owing to their high theoretical discharge capacity and energy ***,the dissolution of long-chain polysulfides into the electrolyte during the charge and discharge process(“shuttle effect”)results in fast capacity fading and inferior electrochemical *** this study,Mn_(2)O_(3)with an ordered mesoporous structure(OM-Mn_(2)O_(3))was designed as a cathode host for LSBs via kiT-6 hard templating,to effectively inhibit the polysulfide shuttle ***-Mn_(2)O_(3)offers numerous pores to confine sulfur and tightly anchor the dissolved polysulfides through the combined effects of strong polar-polar interactions,polysulfides,and sulfur chain *** OM-Mn_(2)O_(3)/S composite electrode delivered a discharge capacity of 561 mAh g-1 after 250 cycles at 0.5 C owing to the excellent performance of OM-Mn_(2)O_(3).Furthermore,it retained a discharge capacity of 628mA h g-1 even at a rate of 2 C,which was significantly higher than that of a pristine sulfur electrode(206mA h g-1).These findings provide a prospective strategy for designing cathode materials for high-performance LSBs.

关键词： host material lithium-sulfur battery ordered mesoporous structure shuttle effect transition-metal oxides

Pathological diagnosis and immunohistochemical analysis of giant retrosternal goiter in the elderly: A case report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2024年第3期12卷 643-649页

作者： Yong-Chang Meng Liu-Sheng Wu Ning Li hong-Wei Li Jing Zhao jun Yan Xiao-Qiang Li Peng Li Jiang-Qi Wei Department of Cardiothoracic Surgery Xinxiang First People's HospitalXinxiang 453000Henan ProvinceChina School of Clinical Medicine Tsinghua UniversityBeijing 100084China Graduate School Qinghai UniversityXining 810016Qinghai ProvinceChina Department of Pathology Xinxiang First People's HospitalXinxiang 453000Henan ProvinceChina Department of Thoracic Surgery Peking University Shenzhen HospitalShenzhen 518036Guangdong ProvinceChina

BACKGROUND Elderly giant retrosternal thyroid goiter is a rare yet significant medical condition,often presenting clinical symptoms that can be confused with other diseases,posing diagnostic and therapeutic *** study aims to delve into the characteristics and potential mechanisms of this ailment through pathological diagnosis and immunohistochemical analysis,providing clinicians with more precise diagnostic and treatment strategies.A 77-year-old male,was admitted to hospital with the chief complaint of finding a goiter in the semilunar month during physical examination,accompanied by *** protruding into the superior mediastinum,the adjacent structure was compressed,the trachea was compressed to the right,and the local lumen was slightly *** patient was diagnosed with giant retrosternal *** dyspnea caused by trachea compression,our department planned to perform giant retrosternal *** results:Tg(+),TTF-1(+),Calcitonin(CT)(I),ki-67(+,about 20%),CD34(-).Retrosternal goiter means that more than 50%of the volume of the thyroid gland is below the upper margin of the *** retrosternal goiter disease is a relatively rare disease,once the disease is diagnosed,it should be timely surgical treatment,and the treatment is more difficult,the need for professional medical team for comprehensive *** The imaging manifestations of giant retrosternal goiter are atypical,histomorphology and immunohistochemistry can assist in its *** article reviews the relevant literature of giant retrosternal goiter immunohisto-chemistry and shows that giant retrosternal goiter is positive for Tg,TTF-1,and ki-67.

关键词： Giant retrosternal goiter Pathology Immunohistochemistry Case report

Rare primary squamous cell carcinoma of the intrahepatic bile duct: A case report and review of literature

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Oncology 2024年第7期15卷 936-944页

作者： Qing-jun Ma Fu-Hai Wang Ning-Ning Yang hong-Long Wei Feng Liu Department of General Surgery The First Affiliated Hospital of Shandong First Medical UniversityJinan 250014Shandong ProvinceChina Department of Respiratory and Critical Care Medicine Shandong Provincial Chest Hospital Affiliated to Shandong UniversityJinan 250013Shandong ProvinceChina

BACKGROUND Cholangiocarcinoma is the most common malignancy of the biliary tree and has a poor *** is the most common pathological type of cho-langiocarcinomas,but rare squamous,adenosquamous,and mucinous variants have been reported without adequate clinical *** SUMMARY This report describes a rare case of primary squamous cell carcinoma(SCC)of the intrahepatic bile *** patient was admitted with a tumor in the hepatic caudate lobe with no obvious clinical *** revealed hepatitis B surface antigen positivity,a slight increase in alfa-fetoprotein to 16.34 ng/mL,and an irregular slightly heterogeneous enhancing lesion in the hepatic caudate lobe,which was initially thought to be hepatocellular *** re-section was performed,and the final pathology suggested a rare primary SCC of the intrahepatic bile *** indicated positivity for villin,partial positivity for p63,and negativity for hepatocyte,CK7,CK8,CK19,and *** ki-67 index was approximately 60%.The patient received six cycles of Tegio chemotherapy.A new lesion was detected in the liver after 15 *** surgery was performed,and the patient was followed-up at a local *** date,no new lesions have been *** Surgery is the first choice for resectable lesions,and combined chemotherapy based on pathology is essential for increasing overall survival.

关键词： Squamous cell carcinoma Bile duct Cholangiocarcinoma Clinical characteristics Treatment Case report

Metastatic stomach lymphoepithelioma-like carcinoma and immune checkpoint inhibitor therapy:A case report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Surgery 2024年第5期16卷 1436-1442页

作者： Guo-Feng Chen jun Wang Yu Yan Song Xu Jian Chen Department of Gastroenterology Surgery The Second Affiliated HospitalZhejiang University School of MedicineHangzhou 310000Zhejiang ProvinceChina Cancer Center Zhejiang UniversityHangzhou 310000Zhejiang ProvinceChina Department of Pathology The Second Affiliated HospitalZhejiang University School of MedicineHangzhou 310000Zhejiang ProvinceChina Department of Gastroenterology The Second Affiliated HospitalZhejiang University School of MedicineHangzhou 310000Zhejiang ProvinceChina

BACKGROUND Pulmonary lymphoepithelioma-like carcinoma(PLELC)is a rare type of nonsmall-cell lung *** lymphoepithelioma-like carcinoma(LELC)metastasis secondary to PLELC has not been reported *** SUMMARY A 64-year-old female was admitted to our hospital for a regular gastroscopy examination with a 6-year history of surgical resection for left *** emission tomography/computed tomography suggested high accumulation of 18F-fludeoxyglucose in the gastric cardia *** gastrointestinal endoscopy confirmed a large mass at the stomach ***(IHC)of the biopsy suggested metastatic stomach *** gastrectomy showed that this 6.5 cm×5.0 cm mass was located in the stomach fundus near the *** examination showed a poorly differentiated carcinoma with prominent lymphoplasmacytic *** demonstrated that the tumor was positive for CK(AE1/AE3),p63,p40,p53,ki-67(70%),and EGFR(3+)and negative for CK7,CK20,Her2,and *** situ hybridization analysis showed positive staining Epstein-Barr virus-encoded *** programmed cell death ligand 1(PD-L1)expression score was 98%,and the combined positive score was 100,with no evidence of microsatellite ***,the patient was unequivocally diagnosed with metastatic stomach LELC secondary to pulmonary *** discharge,this patient underwent PD-1 inhibitor treatment(toripalimab,240 mg)every 3 wk for ten cycles,and she has had no tumor *** For gastric LELC metastasis,PD-1 inhibitor therapy could become a new therapeutic approach,though there is still no evidence from large data sets to support this.

关键词： Stomach neoplasm Pulmonary lymphoepithelioma-like carcinoma Metastasis Immune checkpoint inhibitor Case report

Repair of a large patellar cartilage defect using human umbilical cord blood-derived mesenchymal stem cells:A case report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2022年第34期10卷 12665-12670页

作者： jun-Seob Song ki-Taek hong ki Jeon Song Seok jung kim Department of Orthopedic Surgery Gangnam JS HospitalSeoul 06053South Korea Department of Orthopedic Surgery Uijeongbu Street Mary’s HospitalCollege of MedicineThe Catholic University of KoreaUijeongbu 11765GyeonggidoSouth Korea

BACKGROUND Patellar dislocation may cause cartilage defects of various *** defects commonly require surgical treatment;however,conventional treatments are *** SUMMARY A 15-year-old male with a large patellar cartilage defect due to patellar dislocation was treated via human umbilical cord blood-derived mesenchymal stem cell(hUCB-MSC)*** our knowledge,this is the first report of this treatment for this *** patient recovered well as indicated by good visual analog scale,International Knee Documentation Committee and McMaster Universities Osteoarthritis Index *** resonance imaging showed cartilage regeneration 18 mo *** Umbilical cord blood-derived hUCB-MSCs may be a useful treatment option for the repair of large patellar cartilage defects.

关键词： Cartilage defect Umbilical cord Mesenchymal stem cells Patellar dislocation Magnetic resonance imaging Case report

Marker ki-67 is a potential biomarker for the diagnosis and prognosis of prostate cancer based on two cohorts

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2024年第1期12卷 32-41页

作者： Zhen Song Qi Zhou Jiang-Lei Zhang jun Ouyang Zhi-Yu Zhang Department of Urology Taixing People’s HospitalTaizhou 225400Jiangsu ProvinceChina Department of Urology The First Affiliated Hospital of Soochow UniversitySuzhou 215000Jiangsu ProvinceChina Department of Reproductive Medicine Center The First Affiliated Hospital of Soochow UniversitySuzhou 215000Jiangsu ProvinceChina

BACKGROUND Prostate cancer(PCa)is a widespread malignancy,predominantly affecting elderly males,and current methods for diagnosis and treatment of this disease continue to fall *** marker ki-67(Mki67)has been previously demonstrated to correlate with the proliferation and metastasis of various cancer cells,including those of ***,verifying the association between Mki67 and the diagnosis and prognosis of PCa,using bioinformatics databases and clinical data analysis,carries significant clinical *** To explore the diagnostic and prognostic efficacy of antigens identified by Mki67 expression in *** For cohort 1,the efficacy of Mki67 diagnosis was evaluated using data from The Cancer Genome Atlas(TCGA)and Genotype-Tissue Expression(GTEx)*** cohort 2,the diagnostic and prognostic power of Mki67 expression was further validated using data from 271 patients with clinical *** In cohort 1,Mki67 expression was correlated with prostate-specific antigen(PSA),Gleason Score,T stage,and N *** receiver operating characteristic(ROC)curve showed a strong diagnostic ability,and the Kaplan-Meier method demonstrated that Mki67 expression was negatively associated with the progression-free interval(PFI).The time-ROC curve displayed a weak prognostic capability for Mki67 expression in *** cohort 2,Mki67 expression was significantly related to the Gleason Score,T stage,and N stage;however,it was negatively associated with the *** time-ROC curve revealed the stronger prognostic capability of Mki67 in patients with *** COX regression analysis was performed to select risk factors,including PSA level,N stage,and Mki67 expression.A nomogram was established to predict the 3-year *** Mki67 expression was positively associated with the Gleason Score,T stage,and N stage and showed a strong diagnostic and prognostic ability in PCa.

关键词： Marker ki-67 Prostate cancer Biomarker Diagnosis Prognosis

Transparent neural implantable devices:a comprehensive review of challenges and progress

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

npj Flexible Electronics 2022年第1期6卷 439-456页

作者： Young Uk Cho Se Lin Lim jung-Hoon hong ki jun Yu Department of Electrical and Electronic Engineering Yonsei UniversitySeoulKorea Department of Electrical and Electronic Engineering YU-Korea Institute of Science and Technology InstituteYonsei UniversitySeoulKorea

The key to designing an implantable device lies in condensing the synergistic effects of diagnostic and therapeutic methods in a single *** conjunction with the integration of electrophysiology and optical modalities,a transparent neural interface alleviates challenges of conventional metal-based *** this review,the multimodal sensing and stimulation functionalities of recent research are ***,issues that arise when combining functionalities of conventional metal-based,opaque electrode arrays together with optical modalities—(1)photoelectric artifacts,(2)optical image blocking,and(3)light transmission efficiency—are ***,an introduction of advancing material candidates for transparent neural interfaces follows with the latest research.

关键词： neural transparent modal

Curcumin inhibits colorectal cancer development by blocking the YAP/TAZ signaling axis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

BIOCELL 2024年第3期48卷 443-451页

作者： FEI SHA DAISHAN XIN jun XU ZHIWEI ZHENG WENXIN LIN XIAORUI CAI FEI LIN MINGHAO ZHENG JIAOLING CHEN Department of Pharmacy Affiliated Cancer Hospital of Shantou University School of MedicineShantouChina Department of Pharmacy Shantou University Mental Health CenterShantouChina Static Distribution Center Affiliated Cancer Hospital of Shantou University School of MedicineShantouChina

Background:Curcumin is a plant polyphenol with antitumor properties and inhibits the development of colorectal cancer(CRC).However,as the molecular mechanism associated is still unclear,our study aimed to explore the underlying molecular mechanisms by which curcumin inhibits ***:HT29 and SW480 cells were treated with curcumin or/and Doxycycline(DOX),and cell viability,colony forming ability,migration and invasion were conﬁrmed by cell counting kit-8(CCK-8),colony forming,Transwell *** Yes-associated protein 1(YAP)and PDZ-binding motif(TAZ)signaling-related genes or proteins were analyzed using reverse transcription quantitative real-time PCR(RT-qPCR),western blot,and immunoﬂuorescence *** nude mice xenograft tumor model was constructed,YAP and ki67 expressions were tested by immunohistochemistry(IHC)***:In our study,we proved that curcumin signiﬁcantly inhibited the CRC cell viability,cell migration,and cell invasion *** addition,curcumin inhibited YAP and Transcriptional coactivator with TAZ or the YAP/TAZ signaling axis in CRC ***,in the nude mice model,curcumin treatment signiﬁcantly decreased the size and weight of xenotransplant ***:Therefore,curcumin signiﬁcantly inhibited CRC development and invasion by regulating the YAP/TAZ signaling axis.

关键词： Curcumin Colorectal cancer YAP/TAZ signaling axis

Ransomware Classification Framework Using the Behavioral Performance Visualization of Execution Objects

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2022年第8期72卷 3401-3424页

作者： jun-Seob kim ki-Woong Park Department of Computer and Information Security and Convergence Engineering for Intelligent DroneSejong UniversitySeoul05006Korea

A ransomware attack that interrupted the operation of Colonial Pipeline(a large *** pipeline company),showed that security threats by malware have become serious enough to affect industries and social infrastructure rather than individuals *** agents and characteristics of attacks should be identified,and appropriate strategies should be established accordingly in order to respond to such *** this purpose,the first task that must be performed is malware *** creators are well aware of this and apply various concealment and avoidance techniques,making it difficult to classify *** study focuses on new features and classification techniques to overcome these *** propose a behavioral performance visualization method using utilization patterns of system resources,such as the central processing unit,memory,and input/output,that are commonly used in performance analysis or tuning of *** extracted the usage patterns of the system resources for ransomware to performbehavioral performance *** results of the classification performance evaluation using the visualization results indicate an accuracy of at least 98.94%with a 3.69%loss ***,we designed and implemented a framework to perform the entire process—from data extraction to behavioral performance visualization and classification performance measurement—that is expected to contribute to related studies in the future.

关键词： Behavioral performance visualization ransomware malware classification