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Porcine Placenta Extract Enhances Ceramide Synthase 3 Expression through the PPARδ /ILK/Akt/mTOR/STAT3 Pathway

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Application of Dual-Energy Computed Tomography for Breast Cancer Diagnosis

Journal of Cosmetics, Dermatological Sciences and Applications（化妆品、皮肤病及应用期刊） 2022年第3期

作者： akihiro aioi ryuta muromoto jun-ichi kashiwakura sho mogami megumi nishikawa shigeyuki ogawa tadashi matsuda

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International Journal of Medical Physics, Clinical Engineering and Radiation Oncology 2016年第4期5卷 288-297页

作者： Yukiko Okamura Nobuko Yoshizawa Masaru Yamaguchi Ikuo kashiwakura Department of Radiological Life Sciences Hirosaki University Graduate School of Health Sciences Hirosaki Japan Department of Diagnostic Radiology and Nuclear Medicine Hamamatsu University School of Medicine Hamamatsu Japan

The present study aimed to investigate the possibility of using dual-energy computed tomography (CT) before therapy to discriminate between normal breast tissue and tumor tissue in patients with breast cancer, without the need to use a contrast medium. The following patient data were extracted by interview and from the hospital’s radiology information system: height, weight, age, menstrual cycle, CT images of normal tissue and tumors with or without contrast medium, and the histopathological diagnosis of the aspiration biopsy. The median age of the 43 participants was 56 years (range, 30 - 80 years). The CT values were evaluated using a clinical analytical program based on the three-material decomposition technique. Breast cancer was classified into ductal carcinoma in situ, invasive ductal carcinoma, invasive lobular carcinoma, fibromatosis-like metaplastic carcinoma, and apocrine carcinoma. In all conditions, regardless of contrast medium, the CT values of tumor tissues were higher than those of normal breast tissue, indicating the effectiveness of dual-energy CT (DE-CT) in the diagnosis of breast cancer. By contrast, DE-CT showed limited potential for distinguishing ductal carcinoma in situ from invasive ductal carcinoma. There have only been a few reports regarding CT examination of breast cancer, and it is expected this study encourage the development of DE-CT imaging to improve tumor detection in patients with breast cancer.

关键词： Breast Cancer Dual-Energy CT CT Value Contrast Medium Oncological Imaging Ductal Carcinoma in Situ Invasive Ductal Carcinoma

Dissolution of Rare Earth Elements from Coal Fly Ash Particles in a Dilute H<sub>2</sub>SO<sub>4</sub>Solvent

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Open Journal of Physical Chemistry 2013年第2期3卷 69-75页

作者： Shunsuke kashiwakura Yuichi Kumagai Hiroshi Kubo Kazuaki Wagatsuma Institute for Materials Research Tohoku University Sendai Japan

Recently, the worldwide supply of rare earth element (REE) resources will be severely restricted. On the other hand, coal fly ash particles emitted from coal-fired electric power plants contain relatively high concentrations of REEs. The contents of REEs in coal fly ash are regularly several hundreds of ppmw. In order to extract and recover REEs from coal fly ash particles, as a first step, we have investigated their dissolution behavior in a dilute H2SO4 solvent. The REE content of coal fly ash specimens has been precisely determined, and their presence in the ash component of the original coal and their enrichment in coal fly ash particles during coal combustion have been suggested. REEs in coal fly ash dissolve gradually in H2SO4 over time, and this implies two types of occurrences of the REEs in coal fly ash particles. By applying the unreacted core model to the dissolution behavior of REEs in a H2SO4 solvent, we can explain both types of occurrences.

关键词： Coal Fly Ash Rare Earth Elements Dissolution Behavior Unreacted Core Model

Survey on the Consciousness of Japanese Women Regarding Dense Breasts on Mammography

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Advances in Breast Cancer Research 2019年第4期8卷 135-146页

作者： Ikumi Kataoka Ryuko Kawashima Yumiko Tsubota Yumiko Fukkoshi Hiroaki Kawashima Haruhiko Fukuta Ikuo kashiwakura Department of Radiation Science Graduate School of Health Sciences Hirosaki University Hirosaki Aomori Japan Tsugaru Citizen Clinic Aomori Japan Aomori General Health Examination Center Aomori Japan Public Noheji Hospital Kamikitagun-Nohejimachi Aomori Japan Aomori City Hospital Aomori Japan Medical Court Hachinohe-Nishi Hospital Hachinohe Aomori Japan

Patients with dense breasts on mammography have a higher risk of developing breast cancer and missing a tumor mass than those with non-dense breasts. Whether examinees who have dense breasts should be notified is currently under consideration in Japan;however, there is concern about the low level of understanding regarding dense breasts. A questionnaire survey on the degree of comprehension regarding dense breasts was conducted among 409 general women of >20 years of age in Hachinohe city in October 2017 and 2018. The results showed that the degree of comprehension was extremely low, as only 35 people (8.5%) responded with, “I know the meaning”;however, 32 of them (91.5%) stated that they would like to be notified in they had dense breasts. In addition, the degree of comprehension regarding dense breasts was significantly greater among those who had a breast cancer screening history (OR = 6.4;95% CI = 2.0 - 19.8;P = 0.001) and a self-examination history than among those with no such history (OR = 2.5;95% CI = 1.1 - 5.8;P = 0.03). However, the degree of comprehension did not differ between participants of years of age or between participants with and without a breast cancer sufferer among their close blood relatives. The present findings to reflect a low understanding of dense breasts on mammography screening and suggest that the degree of comprehension is influenced by the presence or absence of a consultation history and a self-examination history.

关键词： Dense Breasts Comprehension Notification Breast Cancer Screening Japan

人胎盘和脐带血巨核系集落形成细胞的辐射敏感性

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国际放射医学核医学杂志 2001年第1期25卷 42-42页

作者： kashiwakura I,何庆嘉,杨凤桐