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Biomedical and Environmental Sciences 2024年第4期37卷 418-422页

作者： ZHOU jun YAN Yan DONG Ya Wei LIU Xiao Yu WANG Ping LIN Jia Ming DONG Peng Xuan QUAN Rui WANG Rong Tian MI bao Hong CHEN Wei Heng Beijing University of Chinese Medicine Third Affiliated Hospital Beijing 100029China Engineering Research Center of Chinese Orthopaedics and Sports Rehabilitation Artificial Intelligent Ministry of EducationBeijing 100029China Beijing Hepingli Community Health Service Center Beijing 100013China Minimally Invasive Joint Surgery Beijing University of Chinese Medicine Third Affiliated HospitalBeijing 100029China

Knee osteoarthritis(KOA)is a common progressive joint disease with chronic pain and movement disorders as the main clinical *** is a major public health problem worldwide and it imposes serious medical and economic *** accounts for nearly four-fifths of the global Osteoarthritis burden and increases with rising obesity and age[1].There are many reasons for the change in disease prevalence and risk factors,such as urbanization,lifestyle changes,population aging,and sex imbalances.

关键词： Osteoarthritis clinical obesity

Graphite recycling from spent lithium-ion batteries for fabrication of high-performance aluminum-ion batteries

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Rare Metals 2024年第5期43卷 2161-2171页

作者： Li Wang Chao Wang Jing-Yi Zhang Jia-Cheng Qiu Xu-Wang Fu Zi-Rui Zhang Jian-Min Feng Lei Dong Cong-Lai Long De-jun Li Xiao-Wei Wang bao Zhang Jia-Feng Zhang Rui-Rui Zhao College of Physics and Materials Science Tianjin Normal UniversityTianjin300387China National Engineering Laboratory for High Efficiency Recovery of Refractory Nonferrous Metals School of Metallurgy and EnvironmentCentral South UniversityChangsha 410083China School of Chemistry South China Normal UniversityGuangzhou510631China

Efficient extraction of electrode components from recycled lithium-ion batteries(LIBs)and their highvalue applications are critical for the sustainable and ecofriendly utilization of *** work demonstrates a novel approach to stripping graphite anodes embedded with Li^(+)from spent LIBs directly in anhydrous ethanol which can be utilized as high efficiency cathodes for aluminum-ion batteries(AIBs).Recycled graphite(RG)with foam morphology and crystal structure defects was obtained under the action of ultrasonic peeling and gas generation reaction between residual lithium-graphite interlayer compound and *** inherent open structure of RG facilitates the intercalation/deintercalation of chloralum anions(AlCl_(4)^(-))and enhances its AIB cathode *** electrochemical measurements revea that the RG cathode has a specific capacity of 123 m Ah·g^(-1)at a current of 5 A·g^(-1),which is 1.55 times higher than tha of unprocessed natural graphite and 1.25 times higher than that of commercial artificial ***,the RG cathode demonstrated remarkable stability,retaining its high particular capacity of 138.15 mAh·g^(-1)even through2000 times at 10 A·g^(-1)in a low-cost electrolyte consisting of an ionic liquid/urea/AlCl_(3)*** work offers a novel approach to reusing of graphite anode waste materials from LIBs.

关键词： Aluminum ion batteries Lithium-ion batteries Graphite anode Recycling

Clions accelerating interface charge transfer in a Si/InSFaradaic junction photocathode for solar seawater splitting

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Science China Chemistry 2024年

作者： jun Luo Ruotong bao Hongzheng Dong Ye Fu Dongjian Jiang Bo Wang Yuzhan zheng Qiong Wang Wenjun Luo Zhigang Zou Eco-materials and Renewable Energy Research Center (ERERC) Jiangsu Key Laboratory for Nano Technology National Laboratory of Solid State Microstructures College of Engineering and Applied Sciences Nanjing University National Laboratory of Solid State Microstructures and Department of Physics Nanjing University

Photoelectrocatalytic seawater splitting is a promising low-cost method to produce green hydrogen in a large *** effects of Cl-ions in seawater on the performance of a photoanode have been reported in previous ***,few researches have been done on the roles of Cl-ions in a ***,for the first time,we find that Cl-ions in the electrolyte improve the photocurrent of a Si/In2S3photocathode by 50%at-0.6 *** in-situ X-ray photoelectron spectroscopy （XPS） characterization combined with the time-of-flight secondary-ion mass spectrometry by simulating photoelectrochemical conditions was used to investigate the interface charge transfer *** results suggest that there is an In+32S3–x（OH）2xlayer on the surface of In2S3in the phosphate buffer solution （PBS） electrolyte,which plays a role as an interface charge transfer mediator in the Si/*** In+32S3–x（OH）2xsurface layer becomes In+32S3–x（Cl）2xin the PBS electrolyte with NaCl and accelerates the charge transfer rate at the In2S3/electrolyte *** results offer a new concept of regulating interface charge transfer mediator to enhance the performance of photoelectrocatalytic seawater splitting for hydrogen production.

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Human immunodeficiency virus-associated dementia complex with positive 14-3-3 protein in cerebrospinal fluid:A case report

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World Journal of Clinical Cases 2024年第12期12卷 2065-2073页

作者： Yun-Sen He Xiao-Hong Qin Min Feng Qin-Jiang Huang Meng-jun Zhang Li-Li Guo Ming-Bin bao Ye Tao Hong-Yuan Dai Bo Wu Department of Neurosurgery Sichuan Lansheng Brain Hospital&Shanghai Lansheng Brain Hospital Investment Co.Ltd.Chengdu 610036Sichuan ProvinceChina Department of Psychiatry Sichuan Provincial Center for Mental HealthChengdu 610072Sichuan ProvinceChina Department of Geriatrics Municipal People’s Hospital in LuzhouLuzhou 646000Sichuan ProvinceChina Department of Neurosurgery Wenjiang District People’s Hospital of ChengduChengdu 611100Sichuan ProvinceChina Department of Neurosurgery Sichuan Provincial People's HospitalUniversity of Electronic Science and Technology of China ChengduChengdu 610072Sichuan ProvinceChina Department of Neurology Sichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaChengdu 610072Sichuan ProvinceChina

BACKGROUND Human immunodeficiency virus(HIV)-associated dementia(HAD)is a subcortical form of dementia characterized by memory deficits and psychomotor ***,HAD often presents with symptoms similar to those of Creutzfeldt-Jakob disease(CJD),particularly in patients with acquired immune deficiency syndrome(AIDS).CASE SUMMARY We report the case of a 54-year-old male who exhibited cognitive dysfunction and secondary behavioral changes following HIV infection and suspected prion *** patient was diagnosed with HIV during hospitalization and his cerebrospinal fluid tested positive for 14-3-3 *** electroencephalogram showed a borderline-abnormal periodic triphasic wave ***-enhanced magnetic resonance imaging revealed moderate encephalatrophy and ***,symptomatic treatment and administration of amantadine were pursued for presumed CJD,but the patient’s condition continued to *** contrast,the patient’s condition improved following anti-HIV *** individual is also the only patient with this prognosis to have survived over 4 ***,the diagnosis was revised to *** In the diagnostic process of rapidly progressive dementia,it is crucial to rule out as many potential causes as possible and to consider an autopsy to diminish diagnostic *** 14-3-3 protein should not be regarded as the definitive marker for *** laboratory screening for infectious diseases is essential to enhance diagnostic precision,especially in AIDS patients with potential ***,a trial of diagnostic treatment may be considered when additional testing is not feasible.

关键词： HIV-associated dementia Cognitive dysfunction Creutzfeld-Jakob disease Rapidly progressive dementia Case report

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当代中国新闻学自主知识体系的实践呈现方式

编辑之友 2024年第8期 5-13页

作者：杨保军中国人民大学新闻与社会发展研究中心中国人民大学新闻学院

当代中国新闻学自主知识体系构建的实践指向，决定了自主知识体系必然要呈现在实践领域。文章认为，实践呈现方式是新闻学自主知识体系呈现的重要方式之一，且具有终极呈现的意义。当代中国新闻学自主知识体系的实践呈现方式主要包括四... 详细信息

当代中国新闻学自主知识体系构建的实践指向，决定了自主知识体系必然要呈现在实践领域。文章认为，实践呈现方式是新闻学自主知识体系呈现的重要方式之一，且具有终极呈现的意义。当代中国新闻学自主知识体系的实践呈现方式主要包括四个方面：呈现或体现于国家层面的新闻路线、方针、政策中；呈现或实现于国家层面的新闻制度规范中；呈现或体现于所有新闻实践主体的新闻实践观念中；呈现或实现于所有新闻活动主体直接感性的新闻实践活动中。

关键词：当代中国新闻学自主知识体系实践呈现方式

De novo synthesis of atropisomeric benzofurans via Cu/SPDO complex catalyzed asymmetric formal [3 + 2] annulation

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Science China Chemistry 2024年

作者： Fan-Xiao Meng Xing-Yu Wang Ka Lu Ju-Song Yang Fu-Min Zhang Ai-jun Ma bao Du Yong-Qiang Tu State Key Laboratory of Applied Organic Chemistry College of Chemistry and Chemical Engineering Lanzhou University School of Chemistry and Chemical Engineering Shanghai Jiao Tong University School of Biotechnology and Health Sciences Wuyi UniversityJiangmen

Herein, the de novo synthesis of atropisomeric benzofurans through the Cu/spirocyclic-pyrrolidine-oxazoline(SPDO) complex catalyze asymmetric formal [3 + 2] cycloaddition between quinones and ynamides is explored, producing a range of structurally diverse axially chiral benzofurans in satisfactory yields with good to excellent enantioselectivities. Furthermore, density functional theory calculations were applied to explain the possible reaction mechanism.

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Evolution of mechanical properties,localized corrosion resistance and microstructure of a high purity Al-Zn-Mg-Cu alloy during non-isothermal aging

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Journal of Central South University 2024年第6期31卷 1790-1807页

作者： DAI Xuan-xuan LI Yu-zhang LIU Sheng-dan YE Ling-ying bao Chong-jun School of Materials Science and Engineering Central South UniversityChangsha 410083China Key Laboratory of Lightweight and High-strength Structural Materials Changsha 410083China Key Laboratory of Non-ferrous Metals Science and Engineering(Ministry of Education) Changsha 410083China Kunming Metallurgical Research Institute Co. Ltd.Kunming 650031China

The evolution of mechanical properties,localized corrosion resistance of a high purity Al-Zn-Mg-Cu alloy during non-isothermal aging(NIA)was investigated by hardness test,electrical conductivity test,tensile test,intergranular corrosion test,exfoliation corrosion test,slow strain rate tensile test and electrochemical test,and the mechanism has been discussed based on microstructure examination by optical microscopy,electron back scattered diffraction,scanning electron microscopy and scanning transmission electron *** NIA treatment includes a heating stage from 40℃to 180℃with a rate of 20℃/h and a cooling stage from 180℃to 40℃with a rate of 10℃/*** results show that the hardness and strength increase rapidly during the heating stage of NIA since the increasing temperature favors the nucleation and the growth of strengthening precipitates and promotes the transformation of Guinier-Preston(GPI)zones toη'*** the cooling stage,the sizes ofη'phase increase with a little change in the number density,leading to a further slight increase of the hardness and *** NIA proceeds,the corroded morphology in the alloy changes from a layering feature to a wavy feature,the maximum corrosion depth decreases,and the reason has been analyzed based on the microstructural and microchemical feature of precipitates at grain boundaries and subgrain boundaries.

关键词： Al-Zn-Mg-Cu alloy non-isothermal aging mechanical properties localized corrosion resistance microstructure

Design and analysis of an advanced thermal management system for the solar close observations and proximity experiments spacecraft

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Astronomical Techniques and Instruments 2024年第1期1卷 52-61页

作者： Liu Liu Kangli bao Jianchao Feng Xiaofei Zhu Haoyu Wang Xiaofeng Zhang jun Lin Innovation Academy for Microsatellites of Chinese Academy of Sciences Shanghai 201304China Yunnan Observatories Chinese Academy of SciencesKunming 650216China

In this paper,the mission and the thermal environment of the Solar Close Observations and Proximity Experiments(SCOPE)spacecraft are analyzed,and an advanced thermal management system(ATMS)is designed for *** relationship and functions of the integrated database,the intelligent thermal control system and the efficient liquid cooling system in the ATMS are elaborated *** the complex thermal field regulation system and extreme space thermal environment,a modular simulation and thermal field planning method are proposed,and the feasibility of the planning algorithm is verified by numerical simulation.A solar array liquid cooling system is developed,and the system simulation results indicate that the temperatures of the solar arrays meet the requirements as the spacecraft flies by perihelion and *** advanced thermal management study supports the development of the SCOPE program and provides a reference for the thermal management in other deep-space exploration programs.

关键词： Solar Close Observations and Proximity Experiments Adaptive thermal control method Thermal field planning method Pumped liquid cooling system Advanced thermal management system

基于改进SSD的合成孔径声纳图像感兴趣小目标检测方法

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电子学报 2024年第3期52卷 762-771页

作者：李宝奇黄海宁刘纪元刘正君韦琳哲中国科学院声学研究所北京100190 中国科学院先进水下信息技术重点实验室北京100190 中国科学院大学北京100049

轻量化目标检测模型SSD-MV3(Single Shot Detection-MobileNet V3)因输入图像尺寸限制无法直接检测高分辨率大尺寸合成孔径声纳(Synthetic Aperture Sonar,SAS)图像中感兴趣小目标.为此,本文提出了一种新的目标检测方法HRSSD(High Resol... 详细信息

轻量化目标检测模型SSD-MV3(Single Shot Detection-MobileNet V3)因输入图像尺寸限制无法直接检测高分辨率大尺寸合成孔径声纳(Synthetic Aperture Sonar,SAS)图像中感兴趣小目标.为此,本文提出了一种新的目标检测方法HRSSD(High Resolution Single Shot Detection),该方法通过冗余切割确保SSD-MV3输入图像尺寸的规范以及感兴趣小目标的完整,并利用二次非极大值抑制保证检测结果的唯一.此外,提出了一种尺度、空间和通道注意力机制联合的特征提取模块,并利用该模块重新设计了SSD-MV3的基础网络和附加特征提取网络,记作SSD-MV3P(Single Shot Detection-MobileNet V3 Pro),使得SSD-MV3P能更有效的感知感兴趣小目标特征信息.实验结果表明,在感兴趣小目标检测数据集SST(Sonar Small Targets)上,SSD-MV3P的平均检测精度(mean Average Precision,mAP)比SSD-MV3提升4.39%.HRSSD实现了高分辨率大尺寸SAS图像感兴趣小目标的检测,并且保证了同一位置上检测结果的完整性和唯一性.

关键词：合成孔径声纳感兴趣小目标检测轻量化目标检测模型注意力机制二次非极大值抑制

Prediction of treatment response to antipsychotic drugs for precision medicine approach to schizophrenia:randomized trials and multiomics analysis

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Military Medical Research 2024年第1期11卷 19-33页

作者： Liang-Kun Guo Yi Su Yu-Ya-Nan Zhang Hao Yu zhe Lu Wen-Qiang Li Yong-Feng Yang Xiao Xiao Hao Yan Tian-Lan Lu jun Li Yun-Dan Liao zhe-Wei Kang Li-Fang Wang Yue Li Ming Li Bing Liu Hai-Liang Huang Lu-Xian Lv Yin Yao Yun-Long Tan Gerome Breen Ian Everall Hong-Xing Wang Zhuo Huang Dai Zhang Wei-Hua Yue Institute of Mental Health Peking University Sixth HospitalBeijing 100191China National Clinical Research Center for Mental Disorders Peking University Sixth HospitalBeijing 100191China NHC Key Laboratory of Mental Health and Research Unit of Diagnosis and Treatment of Mood Cognitive Disorder(2018RU006) Chinese Academy of Medical SciencesBeijing 100191China Peking University Huilongguan Clinical Medical School Beijing Huilongguan HospitalBeijing 100096China Department of Psychiatry Jining Medical UniversityJining 272067ShandongChina Henan Key Lab of Biological Psychiatry the Second Affiliated Hospital of Xinxiang Medical UniversityXinxiang 435001HenanChina Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province Kunming Institute of ZoologyChinese Academy of SciencesKunming 650223China Institute of Psychiatry Psychology and NeuroscienceKing’s College LondonLondon WC2R 2LSUK State Key Laboratory of Cognitive Neuroscience and Learning Beijing Normal UniversityBeijing 100875China Analytic and Translational Genetics Unit Massachusetts General HospitalBostonMA 02114USA Stanley Center for Psychiatric Research the Broad Institute of MIT and HarvardCambridgeMA 02141USA Department of Medicine Harvard Medical SchoolBostonMA 02115USA Department of Biostatistics and Computational Biology School of Life SciencesFudan UniversityShanghai 200438China Department of Neurology Xuanwu HospitalCapital Medical UniversityBeijing 100053China State Key Laboratory of Natural and Biomimetic Drugs Key Laboratory for Neuroscience for Ministry of EducationSchool of Pharmaceutical SciencesPeking University Health Science CenterBeijing 100191China PKU-IDG/McGovern Institute for Brain Research Peking UniversityBeijing 100871China Chinese Institute for Brain Research Beijing 102206China

Background:Choosing the appropriate antipsychotic drug(APD)treatment for patients with schizophrenia(SCZ)can be challenging,as the treatment response to APD is highly variable and difficult to predict due to the lack of effective *** studies have indicated the association between treatment response and genetic and epigenetic factors,but no effective biomarkers have been ***,further research is imperative to enhance precision medicine in SCZ ***:Participants with SCZ were recruited from two randomized *** discovery cohort was recruited from the CAPOC trial(n=2307)involved 6 weeks of treatment and equally randomized the participants to the Olanzapine,Risperidone,Quetiapine,Aripiprazole,Ziprasidone,and Haloperidol/Perphenazine(subsequently equally assigned to one or the other)*** external validation cohort was recruited from the CAPEC trial(n=1379),which involved 8 weeks of treatment and equally randomized the participants to the Olanzapine,Risperidone,and Aripiprazole ***,healthy controls(n=275)from the local community were utilized as a genetic/epigenetic *** genetic and epigenetic(DNA methylation)risks of SCZ were assessed using the polygenic risk score(PRS)and polymethylation score,*** study also examined the genetic-epigenetic interactions with treatment response through differential methylation analysis,methylation quantitative trait loci,colocalization,and promoteranchored chromatin *** learning was used to develop a prediction model for treatment response,which was evaluated for accuracy and clinical benefit using the area under curve(AUC)for classification,R^(2) for regression,and decision curve ***:Six risk genes for SCZ(LINC01795,DDHD2,SBNO1,KCNG2,SEMA7A,and RUFY1)involved in cortical morphology were identified as having a genetic-epigenetic interaction associated with treatment *** developed and externally validated predictio

关键词： Schizophrenia Antipsychotic drug Treatment response Prediction model Genetics Epigenetics