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Chinese Journal of Chemical Engineering 2024年第4期68卷 27-34页

作者： Xi Quan jun zhang Linlin Yin wei Zuo Yu Tian State Key Laboratory of Urban Water Resource and Environment(SKLUWRE) School of EnvironmentHarbin Institute of TechnologyHarbin 150090China

In this work,a novel composite material based on β-cyclodextrin-immobilized sodium alginate aerogel(β-CD/NaAlg) was developed utilizing cross-linker of epichlorohydrin and applied as an adsorbent to remove tetracycline antibiotics from reclaimed wastewater.A series of characterizations were utilized to confirm the successful synthesis of the adsorbent and this β-CD/NaAlg presented a three-dimensional network at the nanoscale or *** optimal conditions(pH=4,t=8 h,β-CD:NaAlg=9,adsorbent dosage = 1.5 g·L-1),the maximum removal rate of β-CD/NaAlg to tetracycline was 70%.The adsorption behavior of tetracycline on β-CD/NaAlg conformed to the Freundlich isotherm model(R2=0.9977) and the pseudo-second-order kinetic model(R^(2)=0.9993).Moreover,the adsorbent still removed 55.3% of tetracycline after five ***,the adsorbent was integrated with ultrafiltration to adsorb tetracycline antibiotics from simulated reclaimed wastewater,and the removal rate of tetracycline reached 78.9% within 2 *** existence of Cr(Ⅵ) had a negligible impact on tetracycline removal,while the presence of humic acid exhibited a promoting *** possible adsorption mechanisms were also elucidated through X-ray photoelectron spectroscopy and density functional theory *** summary,β-CD/NaAlg represents an environmentally friendly,efficient,and sustainable adsorbent for removing tetracycline antibiotics from reclaimed water.

关键词： b-CD/NaAlg aerogel Covalent grafting Tetracycline antibiotics Ultrafiltration Selective adsorption Reclaimed water

Translocation of telomerase reverse transcriptase coincided with ATP release in postnatal cochlear supporting cells

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Neural Regeneration Research 2024年第5期19卷 1119-1125页

作者： Yukai zhang Keyong Tian wei wei Wenjuan Mi Fei Lu Zhenzhen Liu Qingwen Zhu Xinyu zhang Panling Geng Jianhua Qiu Yongli Song Dingjun zha Department of Otolaryngology Xijing HospitalFourth Military Medical UniversityXi’anShaanxi ProvinceChina

The spontaneous bursts of electrical activity in the developing auditory system are derived from the periodic release of adenosine triphosphate(ATP)by supporting cells in the Kölliker’s ***,the mechanisms responsible for initiating spontaneous ATP release have not been *** previous study revealed that telomerase reverse transcriptase(TERT)is expressed in the basilar membrane during the first postnatal *** role in cochlear development remains *** this study,we investigated the expression and role of TERT in postnatal cochlea supporting *** results revealed that in postnatal cochlear Kölliker’s organ supporting cells,TERT shifts from the nucleus into the cytoplasm over *** found that the TERT translocation tendency in postnatal cochlear supporting cells in vitro coincided with that observed in *** analysis showed that TERT in the cytoplasm was mainly located in mitochondria in the absence of oxidative stress or apoptosis,suggesting that TERT in mitochondria plays roles other than antioxidant or anti-apoptotic *** observed increased ATP synthesis,release and activation of purine signaling systems in supporting cells during the first 10 postnatal *** phenomenon that TERT translocation coincided with changes in ATP synthesis,release and activation of the purine signaling system in postnatal cochlear supporting cells suggested that TERT may be involved in regulating ATP release and activation of the purine signaling *** study provides a new research direction for exploring the spontaneous electrical activity of the cochlea during the early postnatal period.

关键词： apoptosis ATP release Ca2+transients cochlea mitochondrial function reactive oxygen species spontaneous electrical activity supporting cells

Integral precession calibration method of PIGA on linear vibration table

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Chinese Journal of Aeronautics 2024年第3期37卷 219-236页

作者： Chuang SUN Shun-qing REN jun-wei CAO Ru HUO Department of Automation Tsinghua UniversityBeijing 100084China School of Astronautics Harbin Institute of TechnologyHarbin 150001China Beijing National Research Center for Information Science and Technology Tsinghua UniversityBeijing 100084China Faculty of Information technology Beijing University of TechnologyBeijing 100124China

Linear vibration table can provide harmonic accelerations to excite the nonlinear error terms of Pendulous Integrating Gyro Accelerometer(PIGA).Integral precession calibration method is proposed to calibrate PIGA on a linear vibration table in this *** on the precise expressions of PIGA’s inputs,the error calibration model of PIGA is *** angular velocity errors of PIGA are suppressed by integer periodic precession and the errors caused by non-integer periods vibrating are *** complete calibration process,including planning,preparation,PIGA testing,and coefficient identification,is designed to optimize the test operations and evaluate the calibration *** effect of the main errors on calibration uncertainty is analyzed and the relative sensitivity function is proposed to further optimize the test *** and simulation results verify that the proposed 10-position calibration method can improve calibration uncertainties after compensating for the related *** order of calibration uncertainties of the second-and third-order coefficients are decreased to 10^(-8)(rad.s^(-1))/g^(2)and 10^(-8)(rad.s^(-1))/g3,*** with the other two classical calibration methods,the calibration uncertainties of PIGA’s nonlinear error coefficients can be effectively reduced and the proportional residual errors are decreased less than 3×10-6(rad.s^(-1))/g by using the proposed calibration method.

关键词： PIGA Linear vibration table Vibration measurement Calibration Error analysis Uncertainty analysis

Improving hydrogen storage thermodynamics and kinetics of Ce-Mg-Ni-based alloy by mechanical milling with TiF_(3)

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Journal of Magnesium and Alloys 2024年第4期12卷 1593-1607页

作者： Hongwei Shang wei zhang Xin wei Yaqin Li Zeming Yuan jun Li Yanghuan zhang School of Mechanical and Electrical Engineering Chuzhou UniversityChuzhou 239000China Department of Functional Material Research Central Iron and Steel Research InstituteNo.76 Xueyuannan RoadHaidian DistrictBeijing 100081China Key Laboratory of Integrated Exploitation of Bayan-Obo Multi-Metal Resources Inner Mongolia University of Science and TechnologyBaotou 014010China China Rare Earth New Material(weishan)Co. Ltd.Jining 277600China

Mg-based hydrides are too stable and the kinetics of hydrogen absorption and desorption is not *** efficient way to improve these shortcomings is to employ reactive ball milling to synthesize the nanocomposite materials of Mg and *** this experiment,TiF_(3)was selected as an additive,and the mechanical milling method was employed to prepare the experimental *** alloys used in this experiment were the as-cast Ce_(5)Mg_(85)Ni_(10),as-milled Ce_(5)Mg_(85)Ni_(10)and Ce_(5)Mg_(85)Ni_(10)+3 wt.%*** phase transformation,structural evolution,isothermal and non-isothermal hydrogenation and dehydrogenation performances of the alloys were inspected by XRD,SEM,TEM,Sievert apparatus,DSC and *** revealed that nanocrystalline appeared in the as-milled *** with the as-cast alloy,ball milling made the particle dimension and grain size decrease dramatically and the defect density increase *** addition of TiF_(3)made the surface of ball milling alloy particles markedly coarser and more *** milling and adding TiF_(3)distinctly improved the activation and kinetics of the ***,ball milling along with TiF_(3)can decrease the onset dehydrogenation temperature of Mg-based hydrides and slightly ameliorate their thermodynamics.

关键词： Mg-based hydrides TiF_(3) Ball milling Thermodynamics Kinetics

Review and prospects on the low-voltage Na_(2)Ti_(3)O_(7) anode materials for sodium-ion batteries

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Journal of Energy Chemistry 2024年第1期88卷 446-460,I0011页

作者： jun Dong Yalong Jiang Ruxing Wang Qiulong wei Qinyou An Xiaoxing zhang Hubei Key Laboratory for High-efficiency Utilization of Solar Energy and Operation Control of Energy Storage System Hubei University of TechnologyWuhan 430068HubeiChina State Key Laboratory of New Textile Materials and Advanced Processing Technologies Wuhan Textile UniversityWuhan 430200HubeiChina Xiamen Key Laboratory of High-Performance Metals and Materials College of MaterialsXiamen UniversityXiamen 361005FujianChina State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070HubeiChina

Due to its low cost and natural abundance of sodium,Na-ion batteries(NIBs)are promising candidates for large-scale energy storage *** development of ultralow voltage anode materials is of great significance in improving the energy density of ***-voltage anode materials,however,are severely lacking in *** all the reported insertion oxides anodes,the Na_(2)Ti_(3)O_(7) has the lowest operating voltage(an average potential of 0.3 V ***^(+)/Na)and is less likely to deposit sodium,which has excellent potential for achieving NIBs with high energy densities and high *** significant progress has been made,achieving Na_(2)Ti_(3)O_(7) electrodes with excellent performance remains a severe *** paper systematically summarizes and discusses the physicochemical properties and synthesis methods of Na_(2)Ti_(3)O_(7).Then,the sodium storage mechanisms,key issues and challenges,and the optimization strategies for the electrochemical performance of Na_(2)Ti_(3)O_(7) are classified and further ***,remaining challenges and future research directions on the Na_(2)Ti_(3)O_(7) anode are *** review offers insights into the design of high-energy and high-safety NIBs.

关键词： Sodium-ion batteries Low-voltage anode materials Na_(2)Ti_(3)O_(7) Electrochemical performances Electrochemical mechanism

Asymptotic Inference in the Random Coefficient Autoregressive Model with Time-functional Variance Noises

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Acta Mathematicae Applicatae Sinica 2024年第2期40卷 320-346页

作者： En-wen ZHU Zi-wei DENG Han-jun zhaNG jun CAO Xiao-hui LIU Department of Mathematics and Statistics Changsha University of Science and TechnologyChangsha 410114China School of Mathematics and Computational Science Xiangtan UniversityXiangtan 411105China School of Statistics and Data Science and Key Laboratory of Data Science in Finance and EconomicsJiangxi University of Finance and EconomicsNanchang 330013China

This paper considers the random coefficient autoregressive model with time-functional variance noises,hereafter the RCA-TFV *** first establish the consistency and asymptotic normality of the conditional least squares estimator for the constant *** semiparametric least squares estimator for the variance of the random coefficient and the nonparametric estimator for the variance function are constructed,and their asymptotic results are reported.A simulation study is presented along with an analysis of real data to assess the performance of our method in finite samples.

关键词： random coefficient autoregressive model time-functional variance conditional least squares semiparametric least squares

Exploring the effect and mechanisms of Epimedium on diabetic testicular injury using network pharmacology,molecular docking,and cell experiments

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TMR Modern Herbal Medicine 2024年第2期7卷 19-27页

作者： jun-jun wei Qiong-Yao Xu zhao-Wen Pan Yi-wei Tu wei Yu Lan Huang Wen-Liang zha College of Pharmacy Hubei University of Science and TechnologyXianning 437100China Xianning Medical College Hubei University of Science and TechnologyXianning 437100China School of Stomatology and Ophthalmology Xianning Medical CollegeHubei University of Science and TechnologyXianning 437100China

Background:Studying the potential targets and mechanisms of Epimedium for anti-diabetic testicular injury using network pharmacology,molecular docking,and cell ***:Acquisition of major components and targets of Epimedium was based on TCMSP,TCMID,and Symmap databases and retrieval of diabetic testicular injury targets by OMIM,GeneCards,Pharmgkb,and Drugbank *** targets were obtained from the Venny 2.1.0 database and input SRTING data to construct a protein-protein interaction(PPI)network,and key targets were screened in Cytoscape 3.8.0 *** the Gene Ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)enrichment analyses of intersecting targets were conducted through the DAVID ***,AutoDock software was used to verify docking between the main components and the core target *** addition,a Cell Counting Kit-8(CCK-8)assay was used to determine the survival effect of quercetin,the main component of Epimedium,on TM4 sertoli-like cells exposed to palmitic acid(PA).Results:Quercetin,kaempferol and luteolin in epimedium were identified as the main components in the treatment of diabetic testicular *** has core target proteins including MMP9,AKT1,and *** biological process mainly involves the regulation of the apoptotic signaling *** key pathways of KEGG are the AGE-RAGE signaling pathway in diabetic complications,PI3K-Akt and MAPK signaling *** docking results showed that quercetin had the strongest binding ability to ***,PA-challenged cells had a lower survival rate,which was alleviated by the administration of ***:Our findings suggest that Epimedium attenuates diabetes mellitus(DM)-induced testicular injury through AGE-RAGE,PI3K-Akt and MAPK signaling *** insights offer a potential therapeutic strategy for managing DM-induced testicular injury,will be the basis for future clinical research.

关键词： Epimedium diabetic testicular injury network pharmacology molecular docking

Special Issue: Functional Polymer Materials

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Chinese Journal of Polymer Science 2024年第7期42卷 895-896,I0004页

作者： Gu, jun-wei Wang, Du-Jin Shaanxi Key Laboratory of Macromolecular Science and Technology School of Chemistry and Chemical Engineering Northwestern Polytechnical University Xi’an China Beijing National Laboratory for Molecular Sciences CAS Key Laboratory of Engineering Plastics Institute of Chemistry Chinese Academy of Sciences Beijing China

The rapid development of science has led to a significant role for polymer materials in multitude fields,including industry,medicine,energy,and the environment,*** a leading academic journal in the field of polymer,Chinese Journal of Polymer Science has been dedicated to fostering the advancement and utilization of polymer science.

关键词： polymer Polymer Functional

Implications of T cell-mediated tumor killing genes for molecular heterogeneity and clinical stratification in lung adenocarcinoma

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Genes & Diseases 2024年第4期11卷 39-41页

作者： Tong Qiao Beining Yin jun Liang Li wei Department of Thoracic Surgery Henan Provincial People's HospitalZhengzhouHenan 450000China Reproductive Medicine Center The First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan 450052China Department of Breast Surgery Henan Provincial People's HospitalZhengzhouHenan 450000China

Due to the profound heterogeneity exhibited amongst patients with lung adenocarcinoma(LUAD),considerable variances in clinical efficacy emerge.1 For the aims of precision medicine,a clinical instrument to delineate distinct disease phenotypes and anticipate susceptibility to intervention is *** cytotoxicity mediated through T lymphocytes constitutes a pivotal mechanism of anti-tumoral immunity and the foundation for cancer immunotherapy.?Numerous genes regulating the sensitivity of tumor cells to killing mediated by T lymphocytes(GSTKKs)are conducive to satisfying the aforesaid medical necessity.

关键词： clinical mediated adenocarcinoma

Identification of an immune-related gene signature for predicting prognosis and immunotherapy efficacy in liver cancer via cell-cell communication

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World Journal of Gastroenterology 2024年第11期30卷 1609-1620页

作者： jun-Tao Li Hong-Mei zhang wei Wang Dong-Qing wei College of Mathematics and Information Science Henan Normal UniversityXinxiang 453007Henan ProvinceChina College of Computer and Information Engineering Henan Normal UniversityXinxiang 453007Henan ProvinceChina State Key Laboratory of Microbial Metabolism and School of Life Sciences and BiotechnologyShanghai Jiao Tong UniversityShanghai 200240China

BACKGROUND Liver cancer is one of the deadliest malignant tumors *** has provided hope to patients with advanced liver cancer,but only a small fraction of patients benefit from this treatment due to individual *** immune-related gene signatures in liver cancer patients not only aids physicians in cancer diagnosis but also offers personalized treatment strategies,thereby improving patient survival *** several methods have been developed to predict the prognosis and immunotherapeutic efficacy in patients with liver cancer,the impact of cell-cell interactions in the tumor microenvir-onment has not been adequately *** To identify immune-related gene signals for predicting liver cancer prognosis and immunotherapy *** Cell grouping and cell-cell communication analysis were performed on single-cell RNA-sequencing data to identify highly active cell groups in immune-related *** active immune cells were identified by intersecting the highly active cell groups with B cells and T *** significantly differentially expressed genes between highly active immune cells and other cells were subsequently selected as features,and a least absolute shrinkage and selection operator(LASSO)regression model was constructed to screen for diagnostic-related *** genes that were selected more than 5 times in 10 LASSO regression experiments were included in a multivariable Cox regression ***,3 genes(stathmin 1,cofilin 1,and C-C chemokine ligand 5)significantly associated with survival were identified and used to construct an immune-related gene *** The immune-related gene signature composed of stathmin 1,cofilin 1,and C-C chemokine ligand 5 was identified through cell-cell *** effectiveness of the identified gene signature was validated based on experi-mental results of predictive immunotherapy response,tumor mutation burden analysis,immune cell infiltrat

关键词： Liver cancer Cell-cell communication Gene signature Prognosis Immunotherapy Single-cell RNA sequencing