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Network Intrusion Detection Model Based on Ensemble of Denoising Adversarial Autoencoder

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印刷与数字媒体技术研究 2024年第5期 185-194,218页

作者： KE Rui xing Bin SI Zhan-jun ZHANG Ying-xue School of Artificial Intelligence Tianjin University of Science and TechnologyTianjin 300457China

Network security problems bring many imperceptible threats to the integrity of data and the reliability of device services,so proposing a network intrusion detection model with high reliability is of great research significance for network *** to the strong generalization of invalid features during training process,it is more difficult for single autoencoder intrusion detection model to obtain effective results.A network intrusion detection model based on the Ensemble of Denoising Adversarial Autoencoder(EDAAE)was proposed,which had higher accuracy and reliability compared to the traditional anomaly detection *** the adversarial learning idea of Adversarial Autoencoder(AAE),the discriminator module was added to the original model,and the encoder part was used as the *** distribution of the hidden space of the data generated by the encoder matched with the distribution of the original *** generalization of the model to the invalid features was also reduced to improve the detection *** the same time,the denoising autoencoder and integrated operation was introduced to prevent overfitting in the adversarial learning *** on the CICIDS2018 traffic dataset showed that the proposed intrusion detection model achieves an Accuracy of 95.23%,which out performs traditional self-encoders and other existing intrusion detection models methods in terms of overall performance.

关键词： Intrusion detection Noise-Reducing autoencoder Generative adversarial networks Integrated learning

新时代新征程高职院校思政课建设的四个着力点

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思想理论教育导刊 2024年第9期 96-105页

作者：邢玲南京信息职业技术学院马克思主义学院

党的十八大以来,习近平立足国内国际“两个大局”,站在中华民族永续发展的高度,对学校思政课建设作出一系列重要论述,为新时代学校思政课建设指明了方向,提供了遵循。深入学习、切实贯彻习近平的重要指示精神,加强高职院校思政课建设,... 详细信息

党的十八大以来,习近平立足国内国际“两个大局”,站在中华民族永续发展的高度,对学校思政课建设作出一系列重要论述,为新时代学校思政课建设指明了方向,提供了遵循。深入学习、切实贯彻习近平的重要指示精神,加强高职院校思政课建设,需要在建设目标维度上,以高质量发展为主线,推动思政课建设内涵式发展,从“建得好”上下真功夫;在建设方式维度上,以“两个协同”为抓手,不断开辟思政课建设新局面,从“怎么建”上下硬功夫;在建设载体维度上,要以新时代中国特色社会主义思想为核心内容,全面构建思政课程教材体系,从“建什么”上下实功夫;在建设主体维度上,树立“两手抓两手硬”意识,建强思政课建设的两支队伍,从“谁来建”上下巧功夫。

关键词：高高职院校思政课新时代中国特色社会主义

Mesenchymal stem cell therapy for liver fibrosis need“partner”:Results based on a meta-analysis of preclinical studies

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World Journal of Gastroenterology 2024年第32期30卷 3766-3782页

作者： Yan Xu Xue-Song Wang Xiao-Lei Zhou Wen-Ming Lu xing-Kun Tang Yu Jin jun-Song Ye Subcenter for Stem Cell Clinical Translation First Affiliated Hospital of Gannan Medical UniversityGanzhou 341000Jiangxi ProvinceChina School of Rehabilitation Medicine Gannan Medical UniversityGanzhou 341000Jiangxi ProvinceChina Ganzhou Key Laboratory of Stem Cell and Regenerative Medicine Gannan Medical UniversityGanzhou 341000Jiangxi ProvinceChina Department of Medical Genetics School of MedicineTongji UniversityShanghai 200092China Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases Ministry of EducationGannan Medical UniversityGanzhou 341000Jiangxi ProvinceChina

BACKGROUND The efficacy of mesenchymal stem cells(MSCs)in treating liver fibrosis has been demonstrated in several clinical ***,their low survival and liver implantation rates remain *** recent years,a large number of studies in animal models of liver fibrosis have shown that MSCs combined with drugs can improve the efficacy of MSCs in the treatment of liver fibrosis alone and inhibit its progression to end-stage liver *** has inspired new ways of thinking about treating liver *** To investigate the effectiveness and mechanisms of MSCs combined with drugs in treating liver *** Data sources included four electronic databases and were constructed until January *** subjects,interventions,comparators,outcomes,and study design principle were used to screen the literature,and the quality of the literature was evaluated to assess the risk of *** randomised controlled trials were selected,and the final 13 studies were included in the final *** A total of 13 studies were included after *** analysis showed that MSCs combined with drug therapy significantly improved liver function,promoted the repair of damaged liver tissues,reduced the level of liver fibrosis-related indexes,and effectively ameliorated hepatic fibrosis by modulating the hepatic inflammatory microenvironment,promoting the homing of MSCs,and regulating the relevant signaling pathways,and the treatment efficacy was superior to MSCs ***,the combined treatment statistics showed no amelioration in serum albumin levels(standardized mean difference=0.77,95%confidence interval:-0.13 to 1.68,P=0.09).CONCLUSION In conclusion,MSCs combined with drugs for treating liver fibrosis effectively make up for the shortcomings of MSCs in their therapeutic ***,due to the different drugs,the treatment mechanism and effect also ***,more randomized controlled trials are needed to compare the therapeutic effic

关键词： drugs alone partner

The dynamics of traveling wavefronts for a model describing host tissue degradation by bacteria

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International Journal of Biomathematics 2024年第3期17卷 265-287页

作者： xing-xing Yang Guo-Bao Zhang Ge Tian College of Mathematics and Statistics Northwest Normal University Lanzhou Gansu 730070P.R.China

In this paper,we mainly investigate the dynamics of traveling wavefronts for a model describing host tissue degradation by *** first establish the existence of spreading speed,and show that the spreading speed coincides with the minimal wave speed of traveling ***,a lower bound estimate of the spreading speed is ***,we prove that the traveling wavefronts with large speeds are globally exponentially stable,when the initial perturbation around the traveling wavefronts decays exponentially asχ→-∞,but the initial perturbation can be arbitrarily large in other *** adopted methods are the weighted energy and the squeezing technique.

关键词： Host tissue degradation bacterial infection traveling wavefronts minimal wave speed stability

Ten-year observation of corneal densitometry and associated factors following small incision lenticule extraction

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International Journal of Ophthalmology(English edition) 2024年第3期17卷 485-490页

作者： Xiao-Song Han Fei Xia Zhuo-Yi Chen Pei-jun Yao Dong-Mei Yang Jing Zhao xing-Tao Zhou Eye Institute and Department of Ophthalmology Eye&ENT HospitalFudan UniversityShanghai 200031China NHC Key Laboratory of Myopia(Fudan University) Key Laboratory of MyopiaChinese Academy of Medical SciencesShanghai 200031China Shanghai Research Center of Ophthalmology and Optometry Shanghai 200031China Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care(20DZ2255000) Shanghai 200031China

●AIM:To investigate the long-term changes of corneal densitometry(CD)and its contributing elements after small incision lenticule extraction(SMILE).●METHODS:Totally 31 eyes of 31 patients with mean spherical equivalent of-6.46±1.50 D and mean age 28.23±7.38y were ***-scale examinations were conducted on all patients preoperatively and during *** acuity,manifest refraction,axial length,corneal thickness,corneal higher-order aberrations,and CD were evaluated.●RESULTS:All surgeries were completed successfully without complications or adverse ***-year safety index was 1.17±0.20 and efficacy 1.04±*** value of 0–6 mm zones in central layer was statistically significantly lower 10y postoperatively,compared with preoperative values(0–2 mmΔ=-1.62,2–6 mmΔ=-1.24,P<0.01).There were no correlations between CD values and factors evaluated.●CONCLUSION:SMILE is a safe and efficient procedure for myopia on a long-term *** values get lower 10y postoperatively,whose mechanism is to be further discussed.

关键词： myopia small incision lenticule extraction corneal densitometry

Theoretical Exploration of Alloying Effects on Stabilities and Mechanical Properties ofγʹPhase in Novel Co–Al–Nb-Base Superalloys

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Acta Metallurgica Sinica(English Letters) 2024年第7期37卷 1238-1248页

作者： Guan-Cheng Gu Zhao-Jing Han Ze-Yu Chen Zhao-Xuan Li Sheng-Bao Xia Zheng-Ning Li Hua Jin Wei-Wei Xu xing-jun Liu Shenzhen Research Institute of Xiamen University School of Aerospace EngineeringXiamen UniversityXiamen361005China Institute of Materials Genome and Big Data Harbin Institute of TechnologyShenzhen518055China

The new developedγ/γʹCo–Al–Nb-base alloys show great potentials as high-temperature ***,finding appropriate compositions to improve performance of alloys still poses a great challenge to the development of Co–Al–Nb-base *** by the lack of alloying effects on fundamental properties of criticalγʹphase,we systematically performed a theoretical investigation on the effect of alloying elements TM(TM:Ti,V,Cr,Zr,Mo,Ta,W,Re,and Ru)on phase stabilities and mechanical properties of L1_(2)-typeγʹ(Co,Ni)_(3)(Al,Nb).By analyzing the stability ofγʹphase with respect to its competitive B2 and D0_(19) phases,the results shown that Ti,V,and Cr enhance the L1_(2) stability and widen the L1_(2)–D0_(19) energy barrier,in which V yields the maximum *** analysis of electronic structure indicated that the alternation of valence electrons at fermi level would be the atomic origin for doping TM inγʹ*** calculated results of mechanical properties shown that V and Cr are expected to be optimal dopant for enhancing the strength and the ductility ofγʹ*** addition of Ta is also beneficial for enhancing the strength at the slight expense of ductility ofγʹ*** drawing the mechanical maps,the preferred composition range for the phases with desired properties is roughly demarcated in theory for the multi-addition of V/Cr and V/Ta inγʹ*** findings would be useful for optimizing the performance of novelγ/γʹCo–Al–Nb-base superalloys.

关键词： Co-Al-Nb-base superalloys γ/γʹdual-phase Phase stability Mechanical properties First-principle methods

The decrease of conduction failure in pathological pain condition contributes to selective peripheral analgesia

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The decrease of conduction failure in pathological pain cond...

Magnetocaloric effect and phase transition critical behavior of La0.75Sr0.25Mn0.9Co0.1O3 compound synthesized under the high pressure

中国神经科学学会第十二届全国学术会议

作者： Xiu-Chao WANG Hong-Hui MAO Ruo-Fei TIAN Tong-Yao HU Guan-Wen HANG San-Jue HU jun-ling xing Department of Neurobiology and Collaborative Innovation Center for Brain Science School of Basic Medicine Fourth Military Medical University Fourth Military Medical University

Objective Conduction failure is a state in which no nerve impulses are transmitted along the axon instead of continuing spike origination. Though it has been observed peripherally in nociceptive C fibers, little is known about its mechanism and therapeutic potential. Hyperpolarization-activated, cyclic nucleotide-modulated（HCN） channels had been recently reported to distribute along the cell membrane of nociceptors. Pharmacologic blockade of HCN channels by ZD-7288 could alleviate nociceptive responses and produce significant analgesia though limited by its bradycardia effects via HCN4 in the sinoatrial node. The present study is to explore whether HCN channel are involved in the conduction failure and whether perineuronal injection of ZD7288 could be a specific analgesic therapeutics approach. Methods Single fiber recording from mouse model of subcutaneous injection of complete Freund’s adjuvant（CFA）, whole cell patch clamp, animal behavior detection were used for revealing the conduction failure and the effect of ZD7288 on conduction failure and analgesic effect. Results（1） In CFAinjected animal, recordings from single C-fiber displayed a significant reduction of conduction failure, compared with A-fibers.（2） Application of ZD7288 on the main axon of C-fibres markedly enhanced the conduction failure.（3） Behavior detection revealed that a significant analgesic effect was achieved, after perineuronal injection of ZD7288, without motor deficits. Intraperitoneal injection of ZD7288 led to bradycardia（a reduction in heart rate from 300 to 200 beats/min）. In contrast, perineuronal injection of ZD7288 had no significant effects on cardiac rhythm. Conclusion Our data highlight the analgesic potential of local ZD7288 application and identify conduction failure as a novel target for analgesic therapy, with little side effects.

关键词： Conduction failure HCN channel C-fiber Peripheral Analgesia

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Tungsten 2024年第3期6卷 621-632页

作者： Jing Zhao Lei Gao Jian-jun Zhao Wei Wei Hui-Qin Yun Ru xing Huai-Jin Ma Xiang Jin Luo-Meng Chao School of Physical Science and Technology Key Laboratory of Magnetism and Magnetic Materials for Higher Education in Inner Mongolia Autonomous Region Baotou Teachers' College National Key Laboratory of Baiyunobo Rare Earth Resource Research and Comprehensive Utilization Baotou Research Institute of Rare Earths School of Physics and Electronic Information Inner Mongolia Normal University College of Science Inner Mongolia University of Science and Technology

In this study,a novel method is proposed for producing perovskite rare-earth manganese oxide magnetic refrigeration materials that exhibit superior properties compared to similar *** maximum magnetic entropy change values for this sample are 1.44 and 3.75 J·kg-1·K-1for magnetic fields of 2 and 7 T,***,its relative cooling power has been calculated to be 101.96 and 404.78 J·kg-1,indicating good *** results were obtained using the sample synthesized under a pressure of 4 GPa,and the sample has undergone a second phase *** critical behavior of the sample fits well with the mean field *** different magnetic fields,there is a significant overlap between the values of the maximum magnetic entropy change and the temperature-averaged entropy change,indicating that the refrigeration performance of the sample after high pressure can approach its maximum capability.

关键词： High-pressure synthesis Magnetocaloric effect Relative cooling power Magnetic phase transition

Recycling of spent lithium-ion batteries to resynthesize high-performance cathode materials for sodium-ion storage

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Tungsten 2024年第3期6卷 574-584页

作者： Hai-Qiang Gong xing-Yuan Wang Long Ye Bao Zhang xing Ou National Engineering Laboratory for High-Efficiency Recovery of Refractory Nonferrous Metals School of Metallurgy and Environment Central South University

The spent lithium-ion batteries recovery has been brought into focus widely for its environmental imperatives and potential profits from the metal components,such as lithium,cobalt,nickel and ***,the weaker pollution and fewer profits of LiMn2O4cathode dispel the enthusiasm and responsibility of industry ***,a simplified and efncient method to regenerate the sodium-ion cathode materials and separate Li from spent LiMn2O4materials for the profit improvement is *** detail,adjusting the parameters of carbothermal reduction process appropriately,the LiMn2O4spinel structure is destroyed within a short period time and transformed into simple metal *** anticipated,nearly 95 wt.%lithium can be obtained and recovered during the water leaching,while 99 wt.% of manganese can be extracted in acid *** that the leaching residue can return to the carbothermic reduction,leading to a closed-loop economic recycling *** regenerated Na0.67Ni0.3Mn0.7O2cathode displays excellent electrochemical performance with superior cycling stability(the initial capacity reaches 95.9 mAh·g-1,and the retention rate reached 98.3% after 100 cycles at 1 C).The delicate strategy of sodium-ion cathode material regenerated from spent LiMn2O4aims to realize lithium separation and material utilization of manganese simultaneously,providing the instructive suggestion to rise up the recycling profits of spent batteries.

关键词： Manganese Spent battery LiMn 2 O 4 cathode Recycling Regenerated Na 0.67 Ni 0.3 Mn 0.7 O 2 Sodium-ion storage