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Biomedical Perspectives About Women with chronic Pelvic Pain:A Qualitative Analysis

International Journal of clinical Medicine 2012年第5期3卷 411-418页

作者： Paula P.Souza Adriana P.M.S.Romao Ana Marcia S.Nakano julio c.rosa-e-silva Francisco J.candido-dos-Reis Antonio A.Nogueira Omero B.Poli-Neto Department of Gynaecology and Obstetrics School of Medicine University HospitalUniversity of Sao Paulo at Ribeirao PretoRibeirao PretoBrazil Department of Public Health School of NursingUniversity of Sao Paulo at Ribeirao PretoRibeirao PretoBrazil School of Medicine University Hospital University of Sao Paulo at Ribeirao PretoRibeirao PretoBrazil

Because the aetiology of chronic pelvic pain is complex, studies of the condition involve extensive investigation but provide few conclusions. Numerous studies have addressed the experiences of women with chronic pelvic pain, as well as the interaction between those women and their health care providers. Our objective was to investigate how physicians at a specialised clinic perceive the medical care provided to such women. This was a qualitative study employing semi-structured interviews and content analysis. We interviewed seven physicians at the chronic Pelvic Pain Outpatient clinic of the University Hospital, Faculty of Medicine of Ribeir?o Preto, University of S?o Paulo, Brazil. Medical training and practice constituted the central theme of the study, which was subdivided into categories addressing the influence that the current medical training has on the type of medical care provided to women with chronic pelvic pain. Medical practice has been characterised by a reductionist approach to health and illness, as well as by the fragmentation of health care. These characteristics are, to a certain extent, the result of the biomedical model of education, which has been predominant, ignoring social, cultural, psychological and emotional aspects. There is a need to shift the medical paradigms toward a humanistic model of health care. We hope that we have provided a critical view of current medical training and practice, as well as of their effects in various health care settings, particularly in the provision of care to women with chronic pelvic pain.

关键词： chronic Pelvic Pain Biomedical Model Qualitative Research

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Linear OPF-based Robust Dynamic Operating envelopes with Uncertainties in Unbalanced Distribution Networks

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Journal of Modern Power Systems and clean energy 2024年第4期12卷 1320-1326页

作者： Bin Liu julio H.Braslavsky Nariman Mahdavi energy centre Commonwealth Scientific and Industrial Research Organisation(CSIRO)Newcastle 2300Australia the Network Planning Division TransgridSydney 2000Australia the energy Systems Program Energy CentreCommonwealth Scientific and Industrial Research Organisation(CSIRO)Newcastle 2300Australia

Dynamic operating envelopes(DOes),as key enablers to facilitate distributed energy resource(DeR)integration,have attracted increasing attention in the past ***,uncertainties,which may come from load forecasting errors or inaccurate network parameters,have been rarely discussed in DOe calculation,leading to compromised quality of the hosting capacity allocation *** letter studies how to calculate DOes that are immune to such uncertainties based on a linearised unbalanced three-phase optimal power flow(UTOPF)*** uncertain parameters constrained by norm balls,formulations for calculating robust DOes(RDOes)are presented along with discussions on their *** cases,including a 2-bus illustrative network and a representative Australian network,are tested to demonstrate the effectiveness and efficiency of the proposed approach.

关键词： Distributed energy resource(DeR) dynamic operating envelope(DOe) feasible region robust optimisation uncertainty modelling unbalanced optimal power flow

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encroachment drives facilitation at alpine shrublines

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Forest ecosystems 2024年第1期11卷 62-72页

作者： Yafeng Wang eryuan Liang J.julio camarero college of ecology and environment Nanjing Forestry UniversityNanjing210037China State Key Laboratory of Tibetan Plateau earth System Environment and Resources(TPESER)Institute of Tibetan Plateau ResearchChinese Academy of SciencesBeijing100101China Instituto Pirenaico de ecología(IPe-cSIc) Zaragoza50080Spain

Ongoing encroachment is driving recent alpine shrubline dynamics globally,but the role of shrub-shrub interactions in shaping shrublines and their relationships with stem density changes remain poorly ***,the size and age of shrubs from 26 Salix shrubline populations along a 900-km latitudinal gradient(30°-38°N)were measured and mapped across the eastern Tibetan *** pattern analyses were used to quantify the spatial distribution patterns of juveniles and adults,and to assess spatial associations between *** intensity of univariate and bivariate spatial patterns was related to biotic and abiotic *** mark correlation functions with a quantitative mark(shrub height,basal stem diameter,crown width)were also employed to investigate the spatial relationships between shrub traits of juveniles and *** equation models were used to explore the relationships among conspecific interactions,patterns,shrub traits and recruitment dynamics under climate *** shrublines showed clustered patterns,suggesting the existence of conspecific *** patterns of juveniles and conspecific interactions(potentially facilitation)tended to intensify with increasing soil moisture *** warming before 2010 triggered positive effects on population interactions and spatial patterns via increased shrub ***,summer warming after2010 triggered negative effects on interactions through reduced shrub ***,shrub recruitment shifts under rapid climate change could impact spatial patterns,alter conspecific interactions and modify the direction and degree of shrublines responses to *** changes would have profound implications for the stability of alpine woody ecosystems.

关键词： Alpine shrubline Positive interactions Facilitation Spatial clustering Point pattern analyses

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contemplative neuroaesthetics and architecture:A sensorimotor exploration

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Frontiers of Architectural Research 2024年第1期13卷 97-111页

作者： Zakaria Djebbara Juliet King Amir ebadi Yoshio Nakamura julio Bermudez Department of Architecture DesignMediaand TechnologyAalborg UniversityAalborgDenmark Biopsychology und Neuroergonomy Technical University BerlinBerlinGermany Art Therapy Department The George Washington UniversityWashington DCUnited States Department of Neurology Indiana University School of MedicineIndianapolisUnited States Dellustration Washington DCUnited States Pain Research center Division of Pain MedicineDepartment of AnesthesiologyUniversity of Utah School of MedicineUtahUnited States School of Architecture and Planning The Catholic University of AmericaWashington DCUnited States

This paper takes initial steps towards developing a theoretical framework of contemplative neuroaesthetics through sensorimotor *** first argue that this new area has been largely omitted from the contemporary research agenda in neuroaesthetics and thus remains a domain of untapped *** seek to define this domain to foster a clear and focused investigation of the capacity of the arts and architecture to induce phenomenological states of a contemplative *** proposing a sensorimotor account of the experience of architecture,we operationalize how being attuned to architecture can lead to contemplative *** contrasting the externally-induced methods with internally-induced methods for eliciting a contemplative state of mind,we argue that architecture may spontaneously and effortlessly lead to such states as certain built features naturally resonate with our sensorimotor *** suggest that becoming sensible of the resonance and attunement process between internal and external states is what creates an occasion for an externallyinduced contemplative ***,we review neuroscientific studies of architecture,elaborate on the brain regions involved in such aesthetic contemplative responses,provide architectural examples,and point at the contributions that this new area of inquiry may have in fields such as the evidence-based design movement in architecture.

关键词： Neuropheno menology Neuroaesthetics contemplative states Architectural experience Well-being

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Loggerhead Sea Turtles Hand-Reared in captivity: Isotopic Insights into Their Inherent Dietary Variation

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Open Journal of ecology 2024年第5期14卷 435-454页

作者： Brenda Natasha Mejía-Guarnizo carlos julio Polo-silva Guiomar Aminta Jauregui-Romero Antonio Delgado-Huertas centro de Investigaciones en ciencias Marinas (cIcIMAR-IPN) La Paz M&#233xico Marine Biology Program Faculty of Natural Sciences and Engineering Jorge Tadeo Lozano University Santa Marta Colombia Sharky Management and consulting Oldsmar FL USA Programa de conservació n de Tortugas y Mam&#237feros Marinos (ProCTMM) Santa Marta Colombia Instituto Andaluz de ciencias de la Tierra (cSIc-UGR) Armilla Spain

Stable isotope analysis is a widely used method for gathering ecological insights into the diet and feeding habitats of various species. While captive studies often limit lethal sampling and differ from wild conditions, they offer valuable insights into inherent isotopic variations among individuals, which are often assumed to reflect differences between natural populations. In the Sea Turtle conservation Program, loggerhead turtle hatchlings from different nests were fed. Necropsies were conducted on turtles that died during this period, obtaining bone fragments for analysis. We evaluated the isotopic variation of carbon (δ13c) and nitrogen (δ15N) in bone tissue across six turtle nests (n = 66 samples) and assessed differences in Straight carapace Length (ScL, n = 71 samples). Using SIBeR and nicheROVeR in R, we calculated niche width and overlap, while the simmr package determined primary prey assimilation. Despite feeding the hatchlings the same prey, we observed variations in nitrogen isotope assimilation between nests. Nests 4 and 6 had a niche width >1.8‰, indicating consistent consumption frequencies across all prey and >70% niche overlap with other nests. In contrast, nests 1 and 2 showed a narrower niche width (Mugil sp. constituted the primary diet component (>40%) across all groups. This study demonstrates how factors like competition or prey preference can influence the assimilation of diet, even when the source remains constant (inherent variation).

关键词： Stable Isotopes caretta caretta Head-Starting Nests Straight carapace Length

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Photosynthetic Gas exchange and Nitrogen Assimilation in Green Bean Plants Supplied with Two Sources of Silicon

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Phyton-International Journal of experimental Botany 2024年第5期93卷 963-980页

作者： julio c.Anchondo-Páez esteban Sánchez carlos A.Ramírez-estrada Alondra Salcido-Martínez erick H.Ochoa-chaparro Department of Plant Physiology Centro de Investigación en Alimentación y DesarrolloCiudad Delicias33089México

Beans contain a wide range of vitamins,proteins,calcium,and zinc which make them an important food source for many *** meet the demand for bean production worldwide,large amounts of fertilizers and pesticides are ***,the cost of production and environmental impact *** produce food sustainably,the use of beneficial nutrients such as silicon as a biostimulant has been ***,information about the effect of different sources of silicon on the metabolism of bean plants is *** plants *** were grown in pots for 60 days and the effect of foliar application of silicon nanoparticles and the silicon-based biostimulant codasilat 4 concentrations(0,1,2,and 4 mM)on total biomass,yield,photosynthetic pigment concentration,photosynthetic activity,stomatal conductance,transpiration rate,chlorophyll fluorescence,and nitrogen assimilation were *** results obtained showed that the supply of silicon at a dose of 1 mM functioned as a biostimulant,favoring gas exchange and nitrogen assimilation within the plant,which stimulated growth and *** results of this research work allowed a better comprehension of the effects of silicon application through silicon nanoparticles and the biostimulant codasilon the physiology of green bean plants.

关键词： Nanoparticles silicon Phaseolus vulgaris L.

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effect of Aspergillus niger prolyl endopeptidase in patients with celiac disease on a long-term gluten-free diet

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World Journal of Gastroenterology 2024年第11期30卷 1545-1555页

作者： Juan Pablo Stefanolo Verónica Segura Martina Grizzuti Abel Heredia Isabel comino Ana Florencia costa Roberto Puebla María Paz Temprano Sonia Isabel Niveloni Gabriel de Diego María e Oregui edgardo Gustavo Smecuol Mauricio c de Marzi elena F Verdú carolina Sousa julio césar Bai Small Bowel Section Department of MedicineGastroenterology Hospital of Buenos Aires“Dr.C.Bonorino Udaondo”Buenos Aires 1264Argentina Department of Microbiology and Parasitology Faculty of PharmacyUniversity of SevilleSeville 41080Spain Department of Medicine Dr.C.Bonorino Udaondo Gastroenterology HospitalBuenos Aires 1264Argentina Basic and Applied Research Group in Immunology and Bioactives(GIBAIB) Institute of Ecology and Sustainable Development(INEDES)National University of LujanLuján 6700Buenos AiresArgentina Department of Medicine Farncombe Family Digestive Health Research InstituteMcMaster UniversityHamilton L8S 4L8OntarioCanada Facultad de Medicina Universidad del SalvadorBuenos Aires C1051ABBArgentina

BAcKGROUND The gluten-free diet(GFD)has limitations,and there is intense research in the development of adjuvant *** To examine the effects of orally administered Aspergillus niger prolyl endopeptidase protease(AN-PeP)on inadvertent gluten exposure and symptom prevention in adult celiac disease(ceD)patients following their usual *** This was an exploratory,double-blind,randomized,placebo-controlled trial that enrolled ceD patients on a long-term *** a 4-wk run-in period,patients were randomized to 4 wk of two AN-PeP capsules(GliadinX;AVI Research,LLc,United States)at each of three meals per day or *** endpoints were:(1)Average weekly stool gluten immunogenic peptides(GIP)between the run-in and end of treatments and between AN-PeP and placebo;(2)celiac symptom index(cSI);(3)ceD-specific serology;and(4)quality of *** samples were collected for GIP testing by eLISA every Tuesday and Friday during run-ins and *** Forty patients were randomized for the intention-to-treat analysis,and three were excluded from the per-protocol ***,628/640(98.1%)stool samples were *** was undetectable(es,and no differences between treatment arms were *** 0.5%of samples had GIP concentrations sufficiently high(>0.32μg/g)to potentially cause mucosal *** GIP concentration in the AN-PeP arm was 44.7%lower than in the run-in ***-third of patients exhibiting GIP>0.08μg/g during run-in had lower or undetectable GIP after AN-PeP *** with the run-in period,the proportion of symptomatic patients(cSI>38)in the AN-PeP arm was significantly lower(PeP did not result in changes in specific *** This exploratory study conducted in a real-life setting revealed high adherence to the *** AN-PeP treatment did not significantly reduce the overall GIP stool ***,given the observation of a significantly lower prevale

关键词： celiac disease Aspergillus niger prolyl endoprotease Gluten immunogenic peptides Trial Symptoms Real-life trial

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Polyoxidovanadates a new therapeutic alternative for neurodegenerative and aging diseases

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Neural Regeneration Research 2024年第3期19卷 571-577页

作者： Sonia Irais Gonzalez-cano Gonzalo Flores Jorge Guevara julio cesar Morales-Medina Samuel Treviño Alfonso Diaz Faculty of chemical Sciences Benemerita Autonomous University of PueblaPueblaMexico Institute of Physiology Benemerita Autonomous University of PueblaPueblaMexico Department of Biochemistry Faculty of MedicineNational Autonomous University of MexicoMexico CityMexico Animal Reproduction Research center CINVESTAV-Autonomous University of TlaxcalaTlaxcalaMexico

Aging is a natural phenomenon characterized by a progressive decline in physiological integrity,leading to a deterioration of cognitive function and increasing the risk of suffering from chronic-degenerative diseases,including cardiovascular diseases,osteoporosis,cancer,diabetes,and *** is considered the major risk factor for Parkinson’s and Alzheimer’s disease ***,diabetes and insulin resistance constitute additional risk factors for developing neurodegenerative ***,no treatment can effectively reverse these neurodegenerative ***,some antidiabetic drugs have opened the possibility of being used against neurodegenerative *** the previous framework,Vanadium species have demonstrated a notable antidiabetic *** research group evaluated polyoxidovanadates such as decavanadate and metforminium-decavanadate with preventive and corrective activity on neurodegeneration in brain-specific areas from rats with metabolic *** results suggest that these polyoxidovanadates induce neuronal and cognitive restoration *** review aims to describe the therapeutic potential of polyoxidovanadates as insulin-enhancer agents in the brain,constituting a therapeutic alternative for aging and neurodegenerative diseases.

关键词： Alzheimer’s disease antidiabetic brain cognition diabetes insulin neurodegeneration neuroinflammation oxidative stress Vanadium species

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The effect of electrical current on lubricant film thickness in boundary and mixed lubrication contacts measured with ultrasound

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Friction 2024年第8期12卷 1882-1896页

作者： julio A.cAO-ROMeRO-GALLeGOS Saeid TAGHIZADeH Oscar A.AGUILAR-rosaS R.S.DWYeR-JOYce Leonardo I.FARFAN-cABReRA Tecnologico de Monterrey Escuela de Ingeniería y CienciasAve.Eugenio Garza Sada 2501MonterreyN.L.64849México Department of Mechanical engineering Leonardo Centre for TribologyUniversity of SheffieldSheffield S13JDUK

This work explores experimentally the effects of Dc electrical currents on lubricant film thickness alteration in lubricated sliding steel contacts in the boundary and mixed regime as measured by *** experiments were performed in a two-electrode cell-based pin-on-disk tester instrumented with ultrasonic *** and electrified tribological tests were conducted on steel flat-on-flat contacts under various speeds and loads using both a mineral base oil and a gear *** thickness,coefficient of friction(coF),and electrical contact resistance(ecR)were measured during short experiments(30 s)in unelectrified and electrified(1.5 and 3 A)*** results suggest that film thickness,coF,and all ecR are altered by passing Dc currents through the *** particular,film thickness increased and decreased,respectively,by applying electricity at the different speeds and loads *** alterations were majorly ascribed to oil viscosity decrease by local heat and surface oxidation caused by electrical discharge and break down at the interface.

关键词： electrified sliding ultrasonic measurement electric vehicles pin-on-disk

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New therapeutic strategy with extracorporeal membrane oxygenation for refractory hepatopulmonary syndrome after liver transplant: A case report

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World Journal of Transplantation 2024年第1期14卷 210-214页

作者： Belinda Sánchez Pérez María Pérez Reyes Jose Aranda Narvaez julio Santoyo Villalba Jose Antonio Perez Daga claudia Sanchez-Gonzalez julio Santoyo-Santoyo Hepatobiliary and Trasplantation Unit General and Digestive Surgery DepartmentUniversity Regional HospitalMalaga 29010Spain Department of General and Digestive Surgery Regional University Hospital of MalagaMalaga 29010Spain

BAcKGROUND Due to the lack of published literature about treatment of refractory hepatopulmonary syndrome(HPS)after liver transplant(LT),this case adds information and experience on this issue along with a treatment with positive *** is a complication of end-stage liver disease,with a 10%-30%incidence in cirrhotic *** can reverse the physiopathology of this process and restore normal ***,in some cases,refractory hypoxemia persists,and extracorporeal membrane oxygenation(ecMO)can be used as a rescue therapy with good *** SUMMARY A 59-year-old patient with alcohol-related liver cirrhosis and portal hypertension was included in the LT waiting list for *** had good liver function(Model for end-Stage Liver Disease score 12,child-Pugh class B7).He had pulmonary fibrosis and a mild restrictive respiratory pattern with a basal oxygen saturation of 82%.The macroaggregated albumin test result was>*** demonstrated a forced expiratory volume in one second(FeV1)of 78%,forced vital capacity(FVc)of 74%,FeV1/FVc ratio of 81%,diffusion capacity for carbon monoxide of 42%,and carbon monoxide transfer coefficient of 57%.He required domiciliary oxygen at 2 L/min(16 h/d).The patient was admitted to the intensive care unit(IcU)and extubated in the first 24 h,needing high-flow therapy and non-invasive ventilation and inhaled nitric oxide *** was needed after 72 *** to the non-response to supportive therapies,installation of ecMO was decided with progressive recovery after 9 *** was possible on the tenth day,maintaining a high-flow nasal cannula and de-escalating to conventional oxygen therapy after 48 *** was discharged from IcU on postoperative day(POD)20 with a 90%-92%oxygen *** recycling was needed twice for acute *** patient was discharged from hospital on POD 27 with no symptoms,with an 89%-90%oxygen *** Due to the favorable results observed,ecMO could bec

关键词： Liver transplantation Hepatopulmonary syndrome Refractory hypoxemia Treatment extracorporeal membrane oxygenation case report

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