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Complete Hydatidiform Mole at Menopause: A Case Report from Panzi Hospital, Bukavu, Democratic Republic of Congo

Open Journal of Obstetrics and Gynecology 2024年第7期14卷 1010-1017页

作者： julien Bwama De-Joseph Kakisingi Mibi Nsenga Bin Musa Jeff Andrea Mbozi Déborah Kambonesa Salire Dieudonné Kakusu Christine Amisi Tina Aroni Toto Tchass Chasinga Baharanyi Denis Mukwege Mukengere Olivier Nyakio Ngeleza Department of Gynaecology-Obstetrics Faculty of Medicine and Community Health Evangelical University in Africa Bukavu Democratic Republic of Congo Gynaecology-Obstetrics Department Panzi General Referral Hospital Bukavu Democratic Republic of Congo Saint Vincent Hospital Bukavu Democratic Republic of Congo Medical Imaging Department Panzi General Referral Hospital Bukavu Democratic Republic of Congo Anatomopathology Department Panzi General Referral Hospital Bukavu Democratic Republic of Congo Panzi Foundation Bukavu Democratic Republic of Congo Department of Gynaecology-Obstetrics Faculty of Medicine Official University of Bukavu Bukavu Democratic Republic of Congo Department of Gynaecology-Obstetrics Faculty of Medicine University of Kindu Kindu Democratic Republic of Congo

Gestational trophoblastic disease is an abnormal proliferation of trophoblastic tissue during pregnancy. It occurs in women of childbearing age, although a few cases have also been observed in post-menopausal women, although it is extremely rare in the latter. Here we describe a rare case of complete hydatidiform mole in a 56-year-old female patient who presented with genital bleeding combined with nausea and vomiting and a gravid uterus 16 cm in height. The ultrasound findings and the increase in serum β-HCG to 182566.00 mIU/ml suggested a diagnosis of complete hydatidiform mole. Given the post-menopausal state and the future risk of post-molar gestational trophoblastic neoplasia, we opted for total hysterectomy without preservation of the adnexa via a transabdominal approach, followed by antimitotic treatment with methotrexate. The uterus measured 18.45 cm × 11.18 cm with intra cavitary vesicles. Microscopic examination showed chorionic villi of variable size and shape, most of which were dilated and oedematous, associated with trophoblastic cell proliferation and haemorrhage suggestive of complete benign hydatidiform mole. Follow-up showed a consistent decrease in serum β-HCG levels and no evidence of residual disease. A suspicion of gestational trophoblastic disease should be borne in mind when evaluating a patient with peri- or post-menopausal bleeding to avoid delay in diagnosis and treatment.

关键词： Complete Hydatidiform Mole Menopause β-HCG Panzi Bukavu DRC

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Comparing the terrain reversal effect in satellite images and in shaded relief maps:an examination of the effects of color and texture on 3D shape perception from shading

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International Journal of Digital Earth 2019年第4期12卷 442-459页

作者： Arzu Çöltekin julien Biland Department of Geography University of ZurichZurichSwitzerland Department of Geography University of BernBernSwitzerland

Terrain reversal effect(TRE)causes reversed 3D shape perception in satellite images and shaded relief maps(SRMs),and introduces difficulties in identifying landforms such as valleys and *** this paper,in a controlled laboratory experiment,we compare how well 27 participants could identify valleys and ridges over 33 locations using SRMs,color satellite images and grayscale satellite *** main depth cue is shadow both in vertical-view images and ***,the presence of texture and color in images also affect 3D shape *** our participants experience the illusion strongly:with the SRMs,it is very severe(2%accuracy),with grayscale images low but considerably better than SRMs(17.6%accuracy),and slightly worse with color imagery(15.3%accuracy).These differences between SRMs and imagery suggest that the participants who are able to bypass the illusion consciously or subconsciously interpret the photographic *** support this observation further with a cue-strength ***,we provide exploratory analyses of the effects of expertise,global convexity bias,and bistable *** original empirical observations serve towards a better understanding of this visual illusion,and contribute towards nuanced and appropriate solutions to correcting for TRE differently for satellite images and SRMs.

关键词： Terrain reversal relief inversion false topographic perception phenomenon photo interpretation visual illusion user study bistable perception global convexity bias

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Pharmacological attenuation of blood pressure variability

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Acta Pharmacologica Sinica 2005年第11期26卷 1288-1289页

作者： Claude julien France Laboratoire de Physiologie Faculte de Pharmacie Lyon 69373 Universite Claude Bernard Lyon 1

Over the past few years, the research team of ProfessorDing-feng SU has reported an impressive quantity of experimental data about the relationships between blood pressurevariability (BPV) and end-organ damage, a topic of obviousclinical interest. This research work has been summarized ina paper that appeared in the August issue of the renownedjournal Trends in Pharmacological Sciences[1]. The studiesby Su et al provide convincing evidence that BPV is an independent cardiovascular risk factor that should be considered as such and, therefore, might become an important target for therapeutic interventions. Besides these exciting perspectives in the prevention and treatment of cardiovascular

关键词： BPV Pharmacological attenuation of blood pressure variability

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UAV navigation system using line-based sensor pose estimation

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Geo-Spatial Information Science 2018年第1期21卷 2-11页

作者： julien Li-Chee-Ming Costas Armenakis Department of Earth and Space Science and Engineering Geomatics EngineeringLassonde School of EngineeringYork UniversityTorontoCanada

This work presents a mapping and tracking system based on images to enable a small Unmanned Aerial Vehicle(UAV)to accurately navigate in indoor and GPS-denied outdoor environments.A method is proposed to estimate the UAV’s pose(i.e.,the 3D position and orientation of the camera sensor)in real-time using only the on-board RGB camera as the UAV travels through a known 3D environment(i.e.,a 3D CAD model).Linear features are extracted and automatically matched between images collected by the UAV’s onboard RGB camera and the 3D object *** matched lines from the 3D model serve as ground control to estimate the camera pose in real-time via line-based space *** results demonstrate that the proposed modelbased pose estimation algorithm provides sub-meter positioning accuracies in both indoor and outdoor *** is also that shown the proposed method can provide sparse updates to correct the drift from complementary simultaneous localization and mapping(SLAM)-derived pose estimates.

关键词： Pose estimation modelbased tracking navigation GPS-denied environment

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An efficient sensitivity analysis for energy performance of building envelope: A continuous derivative based approach

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Building Simulation 2021年第4期14卷 909-930页

作者： Ainagul Jumabekova julien Berger Aurélie Foucquier UMR 5271 CNRS LOCIEUniversity of Grenoble AlpesUniversity of Savoie Mont Blanc73000ChambéryFrance LaSIE La Rochelle UniversityCNRSUMR 735617000La RochelleFrance CEA LITENDTSINESUniversity of Grenoble AlpesF-38000GrenobleFrance

Within the framework of building energy assessment,this article proposes to use a derivative based sensitivity analysis of heat transfer models in a building ***,global and local,estimators are obtained at low computational cost,to evaluate the influence of the parameters on the model *** of these estimators values allows to reduce the number of model unknown parameters by excluding non-significant parameters.A comparison with variance and regression-based methods is carried out and the results highlight the satisfactory accuracy of the continuous-based ***,for the carried investigations the approach is 100 times faster compared to the variance-based methods.A case study applies the method to a real-world building *** sensitivity of the thermal loads to local or global variations of the wall thermal properties is ***,a case study of wall with window is analyzed.

关键词： heat transfer sensitivity analysis continuous derivative based approach parameter estimation problem DuFort-Frankel numerical scheme sensitivity coefficients

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Biomimetic Autopilot Based on Minimalistic Motion Vision for Navigating along Corridors Comprising U-shaped and S-shaped Turns

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Journal of Bionic Engineering 2015年第1期12卷 47-60页

作者： julien R. Serres Franck Ruffier Aix-Marseille UniversitY CNRS ISM UMR 7287 Biorobotics Lab 13288 Marseille Cedex 09 France

A bioinspired autopilot is presented, in which body saccadic and intersaceadic systems are combined. This autopilot en- ables a simulated hovercraft to travel along corridors comprising L-junctions, U-shaped and S-shaped turns, relying on mini- realistic motion vision cues alone without measuring its speed or distance from walls, in much the same way as flies and bees manage their flight in similar situations. The saccadic system responsible for avoiding frontal collisions triggers yawing body saccades with appropriately quantified angles based simply on a few local optic flow measurements, giving the angle of inci- dence with respect to a frontal wall. The simulated robot negotiates stiff bends by triggering body saccades to realign its tra- jectory, thus traveling parallel with the wall along a corridor comprising sharp turns. Direct comparison shows that the per- formance of this new body saccade-based autopilot closely resembles the behavior of a fly using similar body saccade strategy when flying along a corridor with an S-shaped turn, despite the huge differences in terms of the inertia.

关键词： optic flow collision avoidance body saccades insect flight biorobotics biomimetics

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连接天空与大地斯特拉斯堡大学科学花园天文馆

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室内设计与装修 2024年第8期 80-83页

作者： [法国]frenak+jullien [加拿大]Cardin julien [法国]m+mathieu holdrinet Maxime Delvaux(摄影) 沙漏(编译) 不详

描绘天空、想象宇宙、谈论天文学,斯特拉斯堡大学科学花园天文馆梦幻般的维度,激发了由frenak+jullien (法国)领衔的建筑团队的灵感,并与副建筑师Cardin J ulien (加拿大)和项目建筑师m+mathieu holdrin1t(法国)共同创造了建筑的独特形... 详细信息

描绘天空、想象宇宙、谈论天文学,斯特拉斯堡大学科学花园天文馆梦幻般的维度,激发了由frenak+jullien (法国)领衔的建筑团队的灵感,并与副建筑师Cardin J ulien (加拿大)和项目建筑师m+mathieu holdrin1t(法国)共同创造了建筑的独特形式。该天文馆位于气势恢宏的动物学和地质学研究所之间,由2个深色体量组成,在园内丰富的绿色植物中显得格外醒目:一个截顶圆锥体,用于容纳138个座位的放映室及其入口长廊;一个圆柱体量,用于容纳科学园大厅及相关服务设施。截顶圆锥体直冲云霄,寓意对宇宙知识的永恒探索,而开放的大厅则指向科学园管理的众多场所。

关键词：科学园圆锥体直冲云霄服务设施天文馆绿色植物动物学天文学

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Dissemination of Resistance Integrons and Genes Coding for Blse and Cabapenemases in the Urban Drainage Network in Cote d’Ivoire

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Advances in Microbiology 2024年第5期14卷 268-286页

作者： Coulibaly Kalpy julien Diaby Aboubakar Sidik Vakou N’dri Sabine M’bengue Gbonon Valérie Carole Claon Jean Stephane Yao Kouamé Eric Gnali Gbohounou Fabrice Yéo Yéfougnini Bagré Issa Djaman Allico Joseph Dosso Mireille Pasteur Institute of Ivory Coast Abidjan C&#244te d&#8217Ivoire Fé lix Houphou&#235t-Boigny University Abidjan C&#244te d&#8217Ivoire

Antibiotic resistance has become a major threat to human health worldwide. Environment, particularly the water environment, has long been overlooked as a player in the antibiotic resistance cycle, although its role remains unclear. These can provide an ideal setting for the acquisition and dissemination of antibiotic resistance, as they are frequently affected by anthropogenic activities. The objective of this study was to establish a diffusion map of resistance integrons used as genetic markers of resistance associated with antibiotic resistance conferring genes (ARGs). Total DNA extracts from non-cultivable bacterial communities were used for the analyses. These communities were obtained from wastewater samples from 14 sites upstream and downstream of drainage channels or effluents in the cities of Abidjan, Bouaké, and Yamoussoukro. The results obtained correspond to the number of positives among the treated samples (n = 39). Among the genetic markers of dissemination, class 1 integrons were the most evident in 94.8% of samples in Abidjan (93.3%), Bouaké (100%) and Yamoussoukro (91.6%). Class 2 integrons and class 3 integrons were found respectively in 41% and 51% of all samples. Genes coding for β-lactamases and blaTEM was identified in almost all samples at a rate of 97.4%. A co-presence of the three genes blaTEM, blaSHV and blaCTX-M is also remarkable in the sites of the city of Yamoussoukro. Among the genes coding for carbapenemases, only blaKPC 17.94%, blaNDM 30.76% and blaOXA48 38.46% were detected in the samples.

关键词： Antibiotic Resistance Wastewater Resistance Integrons (RIs) Resistance Genes

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Dual angiogenesis and PD-1 blockade in hepatocellular carcinoma

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Hepatobiliary Surgery and Nutrition 2020年第3期9卷 350-352页

作者： julien Calderaro Département de Pathologie Centre Hospitalier Universitaire Henri MondorAssistance Publique Hôpitaux de ParisCréteilFrance Inserm U955 Team 18UniversitéParis-Est CréteilCréteilFrance

Hepatocellular carcinoma(HCC)is the fourth leading cause of cancer related-death worldwide and its incidence is rising in most western countries(1).

关键词： death carcinoma hepatocellular

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Classification of Sandstone-Related Uranium Deposits

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Journal of Earth Science 2022年第2期33卷 236-256页

作者： Michel Cuney julien Mercadier Christophe Bonnetti Universitéde Lorraine GéoRessourcesCNRSCREGUNancy F54500France 2.State Key Laboratory of Nuclear Resources and EnvironmentEast China University of TechnologyNanchang 330013China

Sandstone type deposits are the most common type of uranium deposits in the world.A large variety of sub-types have been defined,based either on the morphology of the deposits(e.g.,tabular,roll front,etc),or on the sedimentological setting(e.g.,paleovalley,paleochannel,unconformity),or on tectonic or lithologic controls(e.g.,tectonolithologic,mafic dykes/sills),or still on a variety of others characteristics(phreatic oxidation type,interlayer permeable type,multi-element stratabound infiltrational,solution front limb deposit,humate type,etc.),reflecting the diversity of the characteristics of these deposits,but making it difficult to have a clear overview of these ***,uranium deposits occurring in the same sedimentological setting(e.g.,paleochannel),presenting similar morphologies(e.g.,tabular),may result from different genetic mechanisms and thus can be misleading for exploration *** aim of the present paper is to propose a new view on sandstone-related uranium deposits combining both genetic and descriptive *** dual view is indeed of primordial importance because all the critical characteristics of each deposit type,not limited to the morphology/geometry of the ore bodies and their relationships with depositional environments of the sandstone,have to be taken into account to propose a comprehensive classification of uranium *** this respect,several key ore-forming processes,like the physical-chemical characteristics of the mineralizing fluid,have to be used to integrate genetic aspects in the *** a succession of concentration steps,potentially temporally-disconnected,are involved in the genesis of some uranium mineralization,the classification here proposed will focus on the main mechanisms responsible for the formation and/or the location of ore *** objective of this paper is also to propose a robust and widely usable terminology to define and categorize sandstone uranium deposits,considering

关键词： sandstone uranium genetic classification redox control depositional environment fluids ore deposit geology

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