检索结果-南通市图书馆

2017年

作者： (美)朱莉·斯乔(julie Straw)[等]

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胡敏读故事记单词考研英语词汇光盘版 2

丛书名：新航道学校读故事记单词系列丛书

2006年

作者：胡敏 Jeff cheap julie Baecker Ben Thompson 李立新卢琳译

本书收录的所有单词分组后被编写成单独的小故事，故事的编写力求趣味性、可读性强，并注重语言地道，致力于学生通过阅读故事记忆单词从而提高记忆效率。

ISBN: (纸本)7504346233

关键词：英语研究生记忆术词汇入学考试

来源：畅想之星图书光盘版（南... 评论

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态度与动机

作者： (英)朱莉·海(julie Hay)

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利用烟杆制造纤维板的研究

烟草科技 2000年第7期33卷 32-33页

作者：刘立全 Reynaldo c.castro Shirley c.Agrupis julie L.Lorenzo

我们已成功地利用烟杆制成纤维板，这种纤维板符合菲律宾标准协会制订的标准。批量生产表明，用烟杆生产的纤维板比用木材生产的纤维板便宜。目前，私人企业和政府部门正在积极合作，以便使此技术投入工业应用。

关键词：烟杆纤维板综合利用生产技术

Extracranial carotid Atherosclerosis and Acute Ischemic Stroke in a Tertiary Hospital in Burkina Faso

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World Journal of Neuroscience 2019年第2期9卷 39-51页

作者： Alfred Anselme Dabilgou Alassane Dravé julie Marie Adeline Kyelem Hassan Koanda christian Napon Jean Kaboré Department of Neurology University Hospital Yalgado Ouedraogo Ouagadougou Burkina Faso Department of Neurology Regional University Hospital of Ouahigouya Ouahigouya Burkina Faso Department of Neurology University Hospital of Bogodogo Ouagadougou Burkina Faso

Objective: To determine the prevalence and risk factors of carotid atherosclerosis among ischemic stroke patients in a tertiary hospital in Burkina Faso. Methodology: This was a descriptive and analytical retrospective study of patients admitted at neurology department of yalgado Ouedraogo University Teaching Hospital with ischemic stroke and cerebral large vessel atherosclerosis in the period from January 1, 2012 to December 31, 2016. Results: The prevalence of extracranial carotid atherosclerosis was 23.9%. The mean age of patients was 63.5 years (Range 31 - 90 years). The study population included 65% of men and 35% of women. Hypertension was the most common vascular risk factor (75.6%). Stroke was mostly located in the anterior circulation in 23.9%. Low HDL-c was present in 52% of patients. The majority of plaque was homogeneous (85.2%). Plaque were located in carotid bulbar artery (38.5%) followed by common carotid artery (28.2%) and extracranial internal carotid artery (18.6%). According to cerebral lesion, plaque was bilateral in 45.5%, ipsilateral in 42.3% and contralateral in 12.1% of cases. Tight stenosis was found in 30.1% of patients. There was a significant link between male gender and tight stenosis (p = 0.004). Aspirin was the most antiplatelet therapy used (95.5%). Statin therapy was used in 91% of patients. The mean duration of hospitalization was 12.5 days with a mortality rate of 7.1%. conclusions: Our study showed that extra carotid atherosclerosis was the most common cause of ischemic stroke in Burkina Faso. Man gender was most represented than women.

关键词： Ischemic Stroke Extracranial Atherosclerosis Antiplatelet Therapy Burkina Faso

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小小铅笔,大有来头

新东方英语（中学版） 2017年第9期 69-71页

作者： Brandon Specktor julie

1858年3月30日，发明家海门·L·李普曼获得了第一支嵌有橡皮擦的铅笔的专利权，然后以十万美元的价格卖掉了这项专利。信不信由你，一根小小石墨棒让人发财或是破产，这在历史上可不是头一回了。以下便是关于铅笔这一世界上最受喜爱的... 详细信息

1858年3月30日，发明家海门·L·李普曼获得了第一支嵌有橡皮擦的铅笔的专利权，然后以十万美元的价格卖掉了这项专利。信不信由你，一根小小石墨棒让人发财或是破产，这在历史上可不是头一回了。以下便是关于铅笔这一世界上最受喜爱的书写工具的六则故事。1铅笔为什么是黄色的？问问皇帝吧。黄色铅笔从19世纪晚期开始便成了一个传统，那时世界上最好的石墨产自中国。西方的铅笔业巨头想让顾客们知道他们生产的铅笔所用笔芯品质上乘，于是便把铅笔涂成了与中国皇室有关的颜色：黄色。下次当你的朋友们在数学作业上到处画简笔小人时，提醒他们想想这个皇家遗产吧。

关键词：铅笔 19世纪晚期书写工具数学作业专利权李普曼发明家黄色

In vivo hypoglycemic, antinociceptive and in vitro antioxidant activities of methanolic bark extract of crataeva nurvala

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Journal of coastal Life Medicine 2017年第11期5卷 496-500页

作者： Uddin Jalal Karim Samira Gain Dwigbijoy Hassan Mahmudul Sultana julie Azima Khalid Labu Zubair Phytochemical Research Laboratory Department of PharmacyWorld University of Bangladesh151/8 Green RoadDhaka-1205Bangladesh

Objective: To rationalize the folkloric use of hypoglycemic, antinociceptive and antioxidant potentials with phytochemical screening of methanolic bark extract of crataeva nurvala (c. nurvala) in vivo and in vitro. Methods: The collected bark was dried and grinded. The coarse powder was soaked in 2000 mL of 90% methanol for several days then filtrated. At 40 °c the volume of crude methanolic extract (cME) was reduced by a vacuum rotary evaporator, then the aqueous methanol extract was separated into petroleum ether, carbon tetrachloride, and aqueous soluble fractions by Kupchan protocol. Then the extracts were subjected to evaluate in vivo analgesic, hypoglycemic activities in Swiss albino mice model and antioxidant in vitro. Results: In quantitative phytochemical analysis, total phenolic content was found maximum (235.94 mg of GAE/g) in aqueous soluble fraction;in case of antioxidant potentials, DPPH free radical scavenging assay showed Ic50 value of 9.25 μg/mL exhibited by aqueous soluble fraction in comparison to ascorbic acid (8.27 μg/mL) as a reference standard. The cMEs potentially (P ced the acetic acid-induced writhing and increased (P cy period in the tail immersion method at a dose dependent manner. The cME significantly reduced blood sugar level of diabetic rat induced by alloxan monohydrate. conclusions: This study was conducted to validate the extensive use of c. nurvala bark as folk medicine with antinociceptive, hypoglycemic and antioxidant effects. It can be concluded that the bark of c. nurvala possesses good antinociceptive, moderate hypoglycemic and antioxidant activities. However, further chemical and pharmacological revise are needed to elucidate the detail mode of action behind this and identify the responsible active principles.

关键词： crataeva nurvala Antinociceptive Hypoglycemic Antioxidant

SLc26A4 mutation testing for hearing loss associated with enlargement of the vestibular aqueduct

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World Journal of Otorhinolaryngology 2013年第2期3卷 26-34页

作者： Taku Ito julie Muskett Parna chattaraj Byung yoon choi Kyu yup Lee christopher K Zalewski Kelly A King Xiangming Li Philine Wangemann Thomas Shawker carmen c Brewer Seth L Alper Andrew J Griffith Otolaryngology Branch National Institute on Deafness and Other Communication Disorders National Institutes of Health Rockville MD 20850 United States Laboratory of Molecular Genetics National Institute on Deafness and Other Communication Disorders National Institutes of Health Rockville MD 20850 United States Anatomy and Physiology Department Kansas State University Manhattan KS 66506 United States Diagnostic Radiology Department Warren G. Magnuson Clinical Center National Institutes of Health Bethesda MD 20892 United States Renal Division Beth Israel Deaconess Medical Center Harvard Medical School Boston MA 02215 United States

nPendred syndrome （PS） is characterized by autosomal recessive inheritance of goiter associated with a defect of iodide organification, hearing loss, enlargement of the vestibular aqueduct （EVA）, and mutations of the SLc26A4 gene. However, not all EVA patients have PS or SLc26A4 mutations. Two mutant alleles of SLc26A4 are detected in 1/4 of North American or European EVA populations, one mutant allele is detected in another 1/4 of patient populations, and no mutations are de-tected in the other 1/2. The presence of two mutant al-leles of SLc26A4 is associated with abnormal iodide or-ganification, increased thyroid gland volume, increased severity of hearing loss, and bilateral EVA. The pres-ence of a single mutant allele of SLc26A4 is associated with normal iodide organification, normal thyroid gland volume, less severe hearing loss and either bilateral or unilateral EVA. When other underlying correlations are accounted for, the presence of a cochlear malformation or the size of EVA does not have an effect on hearing thresholds. This is consistent with observations of an Slc26a4 mutant mouse model of EVA in which hearing loss is independent of endolymphatic hydrops or in-ner ear malformations. Segregation analyses of EVA in families suggest that the patients carrying one mutant allele of SLc26A4 have a second, undetected mutant allele of SLc26A4, and the probability of a sibling hav-ing EVA is consistent with its segregation as an autoso-mal recessive trait. Patients without any mutations are an etiologically heterogeneous group in which siblings have a lower probability of having EVA. SLc26A4 muta-tion testing can provide prognostic information to guide clinical surveillance and management, as well as the probability of EVA affecting a sibling.

关键词： SLc26A4 Pendred syndrome Genetic test-ing Goiter Hearing loss Vestibular aqueduct Genotype-phenotype correlation

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贫血与脑损伤：问题多，答案少

麻醉与镇痛 2009年第6期5卷 1-15页

作者： Gregory M. T. Hare Albert K. y. Tsui Anya T. McLaren Tenille E. Ragoonanan julie yu c. David Mazer, MD 宋云(译) 闵苏(校) Department of Anesthesia Cara Phelan Trauma Research Centre Keenan Research Centre in the Li Ka Shing Knowledge Institute University of Toronto St. Michael's Hospital Toronto Ontario Department of Physiology University of Toronto Toronto Ontario 不详

大量临床研究显示围手术期患者的脑损伤与急性贫血有关。这种损伤发生在接近于我们普遍认同的输血指征[血红蛋白（Hb）浓度7～8g/dl]，但高于脑组织缺氧的血红蛋白浓度（Hb3～4g／dl）的情况下。但是，贫血引起脑损伤的缺氧和非缺氧机... 详细信息

大量临床研究显示围手术期患者的脑损伤与急性贫血有关。这种损伤发生在接近于我们普遍认同的输血指征[血红蛋白（Hb）浓度7～8g/dl]，但高于脑组织缺氧的血红蛋白浓度（Hb3～4g／dl）的情况下。但是，贫血引起脑损伤的缺氧和非缺氧机制仍不清楚。此外，能最大程度降低急性贫血所致脑损伤的保护性机制仍未阐明。包括一氧化氮（NO）在内的血管扩张机制，在贫血时有助于维持大脑氧供，在各种急性稀释性缺血试验模型中，3种NO合成酶（NOS）（神经型、内皮型及可诱导型NOS）都有上调。近来的实验也证实了在相当于临床缺氧Hb浓度（Hb6—7g/dl）的啮齿类动物的大脑皮质中，重要的转录因子如缺氧诱导因子（HIF）-1α有所增加。这说明急性贫血对脑氧的供需平衡可能造成威胁，在缺氧的情况下，细胞浆中的HIF-1α降解被抑制，HIF-1α积聚成二聚体，移位到细胞核中并增加许多低氧分子的转录。这些低氧分子在贫血的脑组织中的表达也被发现上调，包括红细胞生成素，血管内皮生长因子，可诱导型NOS。此外，非低氧介质，包括细胞因子和血管激素，可以增加HIF-1α的转录。而且，源于NOS的NO也可以在没有组织缺氧时稳定HIF—1α。因此，在贫血时，HIF-1α在低氧和常氧情况下能对脑细胞进行调节。实验研究发现，针对不同类型的细胞，上调的HIF-1α可以表现为神经保护作用或神经毒性作用。在本综述中，我们描述了这些细胞作用过程，对贫血引起的脑损伤和保护机制有了更清晰的认识。贫血引起损伤的可能机制包括脑栓塞、组织缺氧、炎症、活性氧和兴奋性毒性。可能的细胞保护机制包括NOS／NO依赖的细胞氧供增强和包括HIF-1α、红细胞生成素及血管内皮生长因子在内的细胞保护机制。这些激活的细胞机制的总体平衡决定着它们在贫血时的上调是起细胞保护作用还是细胞损伤作用。深入了解这些机制有助于明确什么样的治疗措施可以降低围手术期贫血性脑损伤。

关键词：脑损伤缺氧诱导因子(HIF)-1α 贫血血管内皮生长因子 HIF-1α 诱导型NOS 脑组织缺氧血红蛋白浓度

Negotiating a new chair package:context and considerations

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Family Medicine and community Health 2023年第1期11卷 26-32页

作者： Amanda Weidner Samantha Elwood Richelle Koopman julie Phillips David Schmitz Li Li A Peter catinella Jehni Robinson Nahid Rianon c J Peek Irfan Asif Family Medicine University of WashingtonSeattleWashingtonUSA Association of Departments of Family Medicine LeawoodKansasUSA Family Medicine Oregon Health&Science UniversityPortlandOregonUSA Family and community Medicine University of Missouri School of MedicineColumbiaMissouriUSA Family Medicine Michigan State UniversityEast LansingMichiganUSA Family and community Medicine University of North Dakota School of Medicine and Health SciencesGrand ForksNorth DakotaUSA Family Medicine University of Virginia School of MedicineCharlottesvilleVirginiaUSA Family Medicine Texas Tech University TransmountainEl PasoTexasUSA Family&community Medicine Texas Tech University Health Sciences Center El PasoPaul L.Foster School of MedicineEl PasoTexasUSA Family Medicine University of Southern California Keck School of MedicineLos AngelesCaliforniaUSA Family and community Medicine The University of Texas Health Science Center at Houston John P and Katherine G McGovern Medical SchoolHoustonTexasUSA Family Medicine and community Health University of Minnesota Medical SchoolMinneapolisMinnesotaUSA Family and community Medicine The University of Alabama at Birmingham Heersink School of MedicineBirminghamAlabamaUSA

Negotiating a resource package as a potential new department chair is common practice in academic *** foundations for this negotiation include the historical presence of the department in relation to the broader institution,projections for future growth,accounting for mission/vision,resource needs(space,personnel,finances,etc),faculty and staff development,and external partnerships within and outside the *** similarities in this process across departments,many nuances influence the development of a specific new chair package,such as,department size;desires,perspectives and talents of the incoming chair,the department faculty,the medical school and dean;prevailing agendas and mission imperatives;and the overall priorities of the *** strategy and forethought,a new chair package can promote a successful chair tenure and departmental *** through the Association of Departments of Family Medicine with input from several dozen department chairs and senior leaders,this is intended to serve as a practical guide to new chair packages for chair candidates.

关键词： finance prevailing outside