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Vulvar Rejuvenation Using High-Intensity Focused Ultrasound (HIFU): Fundamentals and Technique

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Journal of Biosciences and Medicines 2022年第12期10卷 239-252页

作者： Fábio dos santos Borges Mylana Almeida de carvalho Carla Barreto Silva de Cerqueira Tais Andrade Cravo Monteiro Isabelle Maria Almeida e Benevides Adriele Machado Dantas Thiago Gusmão da Silva Carolina Barreto Ribeiro Martins dos santos Estácio de Sá University Rio de Janeiro Brazil IDE Faculty—Institute for Educational Development Salvador Brazil Longevitat Clinic—Advanced Aesthetics Salvador Brazi FAINOR Independent College of the Northeast Vitória da Conquista Brazil UFBA Federal University of Bahia Salvador Brazil

Background: The unaesthetic appearance of the female intimate area (vulva, “mound of venus” and perianal region) is a triggering factor of negative psychological responses, embarrassment, anxiety and insecurity in many women. Using rejuvenating equipment for vaginal structure or for the intimate area as a whole is already widespread in the literature, and High-Intensity Focused Ultrasound (HIFU) has proven to be very effective in the clinical practice of many professionals. This study, therefore, aims to describe the fundamentals and applicability that guide the use of HIFU in vulvar rejuvenation. Materials and Methods: Exploratory research was carried out, presented in a narrative review, to highlight the action of HIFU in female intimate rejuvenation. The review explored scientific articles published and available in the following databases: MEDLINE (Medical Literature Analysis and Retrieval System Online), PubMed (National Library of Medicine), SCIELO (Scientific Electronic Library Online), and LILACS (Latin Literature American and the Caribbean in Health Sciences). In addition, some clinical findings obtained through a retrospective analysis of medical records were added to describe the authors’ clinical experience in the use of Focused Ultrasound (HIFU) for vulvar rejuvenation. Results: We verified that the tissues of female external genitalia respond very well to the stimuli of the focused sound waves of the HIFU, being able to produce immediate and lasting results through isolated applications or in association with intradermotherapy or other therapeutic resources. Conclusion: We conclude that using High Intensity Focused Ultrasound aimed at vulvar rejuvenation is safely indicated and assures excellent aesthetic results at the end of the treatment because similarly to other treatment techniques, the thermal stimuli of HIFU are also able to produce an excellent therapeutic response in the dermal tissue of the female intimate area, promoting intense neocollagen

关键词： Intimate Aesthetics Vulvar Rejuvenation Vaginal Rejuvenation HIFU Focused Ultrasound Micro Focused Ultrasound and Cosmetic Gynecology

Stepped machine learning for the development of mineral models: Concepts and applications in the pre-salt reservoir carbonate rocks

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Energy and AI 2021年第1期3卷 167-179页

作者： Lucas Abreu Blanes de Oliveira Luiz Felipe Niedermaier Custodio Thais Bortotti Fagundes Carina Ulsen Cleyton de carvalho Carneiro Petrobras–Petroleo Brasileiro S.A. Avenida Henrique Valadares 28CentroRio de Janeiro20231-030 Rio de JaneiroBrazil Universidade de Sao Paulo USPEscola PolitecnicaPraça Narciso de AndradeVila MathiasSantosSão Paulo 11013-560Brazil

Understanding rock mineralogy is essential for formation evaluation,improving the calculation of porosity and hydrocarbon *** primary method to obtain the mineralogy from a well is by applying a model to the geochemical tool’s chemical ***,creating a mineralogical model presents challenges such as the minerals’chemical composition and the decision to include a mineral in the *** traditional application of machine learning can make mineral models less realistic since conventional training is developed based on a set of minerals with different occurrences,lowering some minerals’*** present research proposes the stepped machine learning(SML),a stepped way to use machine learning to create a mineralogical model from chemical and mineralogical data.A database was assembled with the elemental concentration obtained with XRF analyses and the mineral concentrations obtained with XRD *** chemical elements were Al,Ca,Fe,K,Mg,Mn,Na,Si,and *** minerals were calcite,dolomite,quartz,clays,K-feldspar,plagioclase,and *** algorithms were tested:MLP,GAN,Random Forest,and XGBoost,with XGBoost showing the best *** was applied,where a mineral model results are used to train a subsequent *** allowed for a significant improvement in some models,notably to clays with an increase in R 2 from 0.597 to 0.853,quartz an increase from 0.673 to 0.869,and calcite,from 0.758 to 0.862.A decrease in the mean squared error of these minerals’models was also *** model was applied to the geochemical logs from three wells drilled in the Brazilian pre-salt,and the results were compared with XRD *** SML model was able to honor the mineral concentrations for different *** is demonstrated that the integration between machine learning tools and geological knowledge in SML was crucial for creating a representative mineralogical model.

关键词： minerals quartz reservoir

Fertilization with Nitrogen, Phosphorus and Potassium in Upland Rice Cultivars in the Southern Region of Rondônia, Brazil

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American Journal of Plant Sciences 2015年第14期6卷 2263-2271页

作者： Edimar Rodrigues Soares Robertt Fernandes Laércio da Silva Londero Leandro Galon Fabiana Ferreira Pires Marcelo de Andrade Barbosa Diego Lopes dos santos Samara Cristina Sampaio Correa Everton Augusto Sampaio Correa Remy carvalho dos santos Department of Soil Science S&atilde o Paulo State University (UNESP) Jaboticabal Brazil Department of Agronomy Federal Institute of Education Science and Technology of Rond&ocirc nia (IFRO) Colorado do Oeste Brazil Department of Agronomy College Amazon (FAMA) Vilhena Brazil Department Herbology Federal University of the Border South (UFFS) Erechim Brazil Federal University Mato Grosso (UFMT) Cuiaba Brazil

The upland rice productivity in the state of Rond?nia is still low, in view of the potential of culture. The use of cultivars adapted to different regions and more responsive to fertilizer employed is an essential practice which can change that. The aim of this study was to evaluate the agronomic characteristics and productivity of two upland rice cultivars with nitrogen, phosphorus and potassium (N-P-K) doses in two municipalities in the southern state of Rondonia region. The experimental design was a randomized block design with four replications in a factorial 2 × 2 × 5, with the first factor composed of two cultivars (hybrid Ecco and conventional farming AN Cambará), the second factor, the environment of the two municipalities, Cerejeiras and Vilhena and the third factor of five doses of N-P-K (0-0-0, 30-40-30, 60-60-60, 90-90-90 and 120-100-120 kg·ha-1). The characteristics evaluated were: tillering, number of integers and sterile grains per panicle, weight of 1000 grains, grain yield (kg·ha-1) and whole grain yield. There was no triple interaction between the three factors for any of the traits. The hybrid Ecco has higher tillering ability than AN Cambara and presents fewer sterile grains per panicle, heavier 1000 grains and hence greater productivity. For both cultivars, the highest yields are obtained with a dose of 120-100-120 kg·ha-1 N-P-K. For the Ecco, the productivity is achieved with this dose and the dose of 90-90-90 kg·ha-1 is statistically similar. There is no difference in productivity between the municipalities when the dose of N-P-K is less than 60-60-60 kg·ha-1. The highest yield of whole grains in function of N-P-K fertilization is obtained in Cerejeiras.

关键词： Oryza sativa L. Productivity Hybridization

Chemical Composition and Allelopathic Activity of the Essential Oil from Callistemon viminalis(Myrtaceae)Blossoms on Lettuce(Lactuca sativa L.)Seedlings

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American Journal of Plant Sciences 2014年第24期5卷 3551-3557页

作者： Christiane Maria de Oliveira Maria das Gracas Cardoso Ana Cristina da Silva Figueiredo Maria Laene Moreira de carvalho Cintia Alvarenga santos Fraga de Miranda Luiz Roberto Marques Albuquerque David Lee Nelson Marcos de Souza Gomes Lucilene Fernandes Silva juliana de Andrade Santiago Maria Luisa Teixeira Rafaela Magalhaes Brandao Department of Chemistry Federal University of LavrasLavrasBrazil Centro de Biotecnologia Vegetal/IBB Departamento de Biologia VegetalFaculdade de Ciencias de LisboaUniversidade de LisboaLisbonPortugal Department of Agriculture Federal University of LavrasLavrasBrazil Federal University of Valleys Jequitinhonha and Mucuri DiamantinaBrazil

The extraction of essential oils was performed by using the technique of hydrodistillation modified Clevenger apparatus, identification and quantification of the constituents was achieved by Gas Chromatography coupled to Mass Spectrometry, and Gas Chromatography equipped with a flame ionization detector. Assessment of allelopathic activity was evaluated with the use of the method that assesses the direct contact of essential oils on germination and vigor of lettuce seeds. The major constituents that characterize the essential oil from the flowers of Callistemon viminalis were 1, 8-cineole, α-pinene and limonene at concentrations of 66.9%, 16.0% and 10.0%, respectively. The essential oil presented allelopathic activity at intensities that varied proportionately to the concentration of the essential oil, with a reduction in the percentage of germination and the germination speed index (GSI) of lettuce seeds and in the dry mass and length of shoots and roots of lettuce seedlings.

关键词： Biological Activity Myrtaceae Allelopathy

Clinical use of estimating glomerular filtration rate equ-ations during pregnancy

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Health 2011年第1期3卷 32-36页

作者： Luiz Paulo José Marques Regina Rocco Maria Helena Victor Benedita Calheiros de Novaes Ana Luiza Batista de carvalho Omar da Rosa santos 不详

Background: Kidney disease, even when mild, was once considered so major an impediment to successful pregnancy and so dangerous to the mother’s wellbeing. High-risk pregnancy mainly associated to renal impairment may occur in 10-20% of gestations and it is very important that renal function is closely monitored to prevent or minimize maternal and fetal complications. This study was designed to investigate the performance of Cockcroft-Gault CGeq and the simplified MDRDeq equations in healthy pregnant women to assess renal function. Methods: We studied 167 normal ambulatory pregnant women and kidney function was contemporaneously estimated through the CGeq and the simplified MDRDeq and calculated through the creatinine clearance (Ccr). Serum and urinary creatinine were assayed using Jaffé reaction method in the same AutoAnalyser. Results: When we compared calculated and estimated clearences for measurement of kidney function we observed that CGeq overestimated renal function (CGeq = 168.41 ± 38.80 ml/ min/1.73 m2, Ccr = 146.27 ± 30.49 ml/min / 1.73 m2, p < 0.001), MDRDeq underestimated renal function (Ccr = 146.27 ± 30.49 ml/min / 1.73 m2, MDRDeq = 129.15 ± 29.28 ml/min / 1.73m2, p < 0.001). Conclusions: Our results demonstrated that CGeq overestimated, MDRDeq underestimated significantly kidney function during gestation in healthy women and cannot be recommended to assess renal function in obstetric practice. Ccr remains a useful clinical tool in pregnant women until the development of a specific equation that considers the several important maternal renal physiological alterations and provides the measure of GFR the most unbiased and precise as possible.

关键词： Pregnancy Kidney function Glomerular Filtration Rate MDRD equation Cockcroft-Gault equation.

Congenital Granular Cell Lesion:A Case Report

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Case Reports in Clinical Medicine 2014年第10期3卷 566-569页

作者： Dionline Borges Paulo Bruna Rodrigues Barbosa Jerúsia Oliveira Ibiapina Ana Maria Goncalves Rebelo Teresinha Castello Branco carvalho Lina Gomes dos santos Department of Specialty Medicine Health Sciences CenterFederal University of PiauíTeresinaBrazil Department of Pathology Sao Marcos HospitalTeresinaBrazil

The congenital granular cell lesion is a rare disease that affects newborns. We present a case of a patient with nodular lesions that were located on the anterior part of the maxillary alveolar. The surgical resection... 详细信息

关键词： Congenital Epulis Congenital Granular Cell Lesion Surgery

Osmotic Dehydration of Pineapple Stems in Hypertonic Sucrose Solutions

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Agricultural Sciences 2015年第9期6卷 916-924页

作者： Ronaldo dos santos Falcao Filho Rennan Pereira de Gusmao Wilton Pereira da Silva Josivanda Palmeira Gomes Edvaldo Vasconcelos carvalho Filho Anoar Abbas El-Aouar Federal Institute of Rio Grande do Norte Currais NovosBrazil Federal University of Campina Grande Campina GrandeBrazil Federal University of Rio Grande do Norte Santa CruzBrazil Federal University of Paraíba Joao PessoaBrazil

The present study provides the evaluation in the influence of the variables: temperature (T), concentration of the osmotic solution (C) and ratio of fruit and osmotic solution (F:OS) during the osmotic dehydration of slices of pineapple stem variety Perola, on the responses: water loss (WL), mass loss (ML), gain of solids (GS) and ratio of gain of solids and water loss (GS/WL). The centesimal composition was determined both in the raw material and in the dehydrated product. To optmize the process, the studied factors were: temperature (T), with factorial points -1 equal to 30°C and +1 equal to 50°C;concentration of sucrose solution (C), with factorial points -1 equal to 40 g·100 g-1 and +1 equal to 60 g·100 g-1 and ratio of fruit and osmotic dehydration solution (F:OS), with factorial points -1 and +1 equal to 1:20 and 3:20, respectively. In all essays, the dehydration time was 4 hours. The essays showed that F:OS was not significant in any responses;the models adopted were predictive and fitted for WL and ML, and reasonable for GS and GS/WL. The temperature was the most significant variable in the process;the optimized values were: T= 50°C, C = 40 g 100 g-1 e F:OS = 3:20. The product needs a complementary drying to adapt itself to the legislation demands.

关键词： Pineapple Dried Fruit Experimental Design

Residual Feed Intake as a Measure to Select Genetically Productive Beef Cattle: A Review

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Journal of Agricultural Science and Technology(B) 2020年第2期10卷 118-123页

作者： Tiago Neves Pereira Valente Andréia santos Cezário Wallacy Barbacena Rosa dos santos Jeferson Corrêa Ribeiro Eliandra Maria Bianchini Oliveira Erico da Silva Lima Bruno Borges Deminicis Thasia Martins Macedo Rogério de carvalho Veloso Department of Animal Science Instituto Federal Goiano(IFGoiano)Campus PossePosse City73900-000Goiás StateBrasil Department of Animal Science Instituto Federal Goiano(IFGoiano)Campus MorrinhosMorrinhos City75650-000Goiás StateBrasil Department of Animal Science Faculdades Metropolitanas Unidas(FMU)São Paulo City05607-000São Paulo StateBrazil Department of Animal Science Federal University of Southern Bahia(UFSB-BA)Teixeira de Freitas City45613-204Bahia StateBrazil

Measures such as residual feed intake(RFI)have been increasingly considered to select cattle with superior feed efficiency,as it is a characteristic of feed efficiency calculated as the difference between observed intake and estimated intake considering metabolic weight and the weight *** feed intake is obtained through the multiple regression equation of observed consumption on metabolic mean live weight and weight *** standard was shared among animals into one herd selected for low RFI(high efficiency)and compared to the one selected for high RFI(low efficiency).There was no correlated response in weight per year and in weight gain,and the effectiveness of low RFI selection in reducing feed costs was proven without affecting ***,selection of animals with negative RFI is not done by selecting animals directly according to the size of the viscera,rather it is done indirectly,that is,when selecting the most efficient animals and normally these animals already have the smallest viscera *** RFI is a trait that presents genetic variability,selectable to improve and has moderate heritability,between 0.30 and *** RFI is important because it reduces the direct economic impacts of reduced feed intake,as well as the effects of environmental impact on reducing methane emissions from enteric fermentation of ruminants.

关键词： Feed conversion feed efficiency enteric fermentation

Agronomic Performance of Cultivars of Upland Rice in the Southern of the Region of Rondonia,Brazil

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Agricultural Sciences 2014年第6期5卷 513-518页

作者： Edimar Rodrigues Soares Robertt Fernandes Laercio da Silva Londero Diego Lopes dos santos Samara Cristina Sampaio Correa Everton Augusto Sampaio Correa Remy carvalho dos santos Ariel Pereira Gomes Leandro Galon Fabiana Ferreira Pires Rosilene da Silva Goncalves Department of Soil Science Sao Paulo State University(UNESP)JaboticabalBrazil Department of Agronomy Federal Institute of Education Science and Technology of Rondonia(IFRO)Colorado do OesteBrazil Department of Agronomy College Amazon(FAMA)VilhenaBrazil Agronomist Federal University Mato Grosso(UFMT)CuiabáBrazil Department Herbology Federal University of the Southern Border South(UFFS)ErechimBrazil

The upland rice is grown in most Brazilian states. However, in many of them the yield obtained is low. The choice of cultivar more suited to a particular environment can contribute to increased productivity of this crop. This research aimed to evaluate the performance of a hybrid cultivar of upland rice (Ecco) and five conventional cultivars (BRS Monarca, BRS Primavera, AN Cambará, BRS Sertaneja and BRS MG Curinga) in two environments (Vilhena and Cerejeiras). The tests were conducted in the agricultural year 2010/2011. We evaluated the following characteristics: tillering, panicle number per unit area, number of filled grains per panicle sterile, mass of grains per panicle, 1000 grain weight, grain yield (kg·ha-1) and whole grain yield. There was no cultivar x environment interaction for all traits. Greater tillering, higher panicle number per area, higher productivity and yield of whole grains in the municipality of Cerejeiras were observed, while the highest number of sterile grains per panicle was obtained in Vilhena. The hybrid Ecco highlighted in relation to all other cultivars is in relation to tillering, panicle number per area and grain yield. The municipality of Cerejeiras is the most suitable for the cultivation of upland rice.

关键词： Oryza sativa L. Hybrid Upland Rice Genotype x Environment