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Novel Architecture of Security Orchestration, Automation and Response in Internet of Blended Environment

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Computers, Materials & Continua 2022年第10期73卷 199-223页

作者： Minkyung Lee julian Jang-Jaccard Jin Kwak ISAA Lab Department of Cyber SecurityAjou UniversitySuwon16499Korea Department of Computer Science and Information Technology Massey UniversityAuckland0745New Zealand Department of Cyber Security Ajou UniversitySuwon16499Korea

New technologies that take advantage of the emergence of massive Internet of Things(IoT)and a hyper-connected network environment have rapidly increased in recent *** technologies are used in diverse environments,such as smart factories,digital healthcare,and smart grids,with increased security *** intend to operate Security Orchestration,Automation and Response(SOAR)in various environments through new concept definitions as the need to detect and respond automatically to rapidly increasing security incidents without the intervention of security personnel has *** facilitate the understanding of the security concern involved in this newly emerging area,we offer the definition of Internet of Blended Environment(IoBE)where various convergence environments are interconnected and the data analyzed in *** define Blended Threat(BT)as a security threat that exploits security vulnerabilities through various attack surfaces in the *** propose a novel SOAR-CUBE architecture to respond to security incidents with minimal human intervention by automating the BT response *** Security Orchestration,Automation,and Response(SOAR)part of our architecture is used to link heterogeneous security technologies and the threat intelligence function that collects threat data and performs a correlation analysis of the *** is operated under Collaborative Units of Blended Environment(CUBE)which facilitates dynamic exchanges of data according to the environment applied to the IoBE by distributing and deploying security technologies for each BT type and dynamically combining them according to the cyber kill chain stage to minimize the damage and respond efficiently to BT.

关键词： Blended threat(BT) collaborative units for blended environment(CUBE) internet of blended environment(IoBE) security orchestration,automation and response(SOAR)

Matching authority and VGI road networks using an extended node-based matching algorithm

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Geo-Spatial Information Science 2015年第2期18卷 65-80页

作者： Ehsan ABDOLMAJIDI Ali MANSOURIAN julian WILL Lars HARRIE GIS Center Department of Physical Geography and Ecosystem ScienceLund UniversitySölvegatan 1222362 LundSweden

The amount of volunteered geographic information(VGI)has increased over the past decade,and several studies have been conducted to evaluate the quality of VGI *** this study,we evaluate the completeness of the road network in the VGI data set OpenStreetMap(OSM).The evaluation is based on an accurate and efficient network-matching *** study begins with a comparison of the two main strategies for network matching:segment-based and nodebased *** comparison shows that the result quality is comparable for the two strategies,but the node-based result is considerably more computationally ***,we improve the accuracy of node-based algorithm by handling topological relationships and detecting patterns of complicated network ***,we conduct a case study on the extended node-based algorithm in which we match OSM to the Swedish National Road Database(NVDB)in Scania,*** case study reveals that OSM has a completeness of 87%in the urban areas and 69%in the rural areas of *** accuracy of the matching process is approximately 95%.The conclusion is that the extended node-based algorithm is sufficiently accurate and efficient for conducting surveys of the quality of OSM and other VGI road data sets in large geographic regions.

关键词： geographic data volunteered geographic information(VGI) OpenStreetMap(OSM) node-based matching segment-based matching pattern detection Swedish National Road Database(NVDB)

Interactome Analysis of Microtubule-targeting Agents Reveals Cytotoxicity Bases in Normal Cells

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Genomics, Proteomics & Bioinformatics 2017年第6期15卷 352-360页

作者： Andres julian Gutierrez-Escobar Gina Mendez-Callejas Grupo de Investigaciones Biomedicas y Genetica Aplicada-GIBGA Universidad de Ciencias Aplicadas y Ambientales U.D.C.A.Bogota 111166Colombia

Cancer causes millions of deaths annually and microtubule-targeting agents （MTAs） are the most commonly-used anti-cancer drugs. However, the high toxicity of MTAs on normal cells raises great concern. Due to the non-selectivity of MTA targets, we analyzed the interaction net- work in a non-cancerous human cell. Subnetworks of fourteen MTAs were reconstructed and the merged network was compared against a randomized network to evaluate the functional rich- ness. We found that 71.4% of the MTA interactome nodes are shared, which affects cellular pro- cesses such as apoptosis, cell differentiation, cell cycle control, stress response, and regulation of energy metabolism. Additionally, possible secondary targets were identified as client proteins of interphase microtubules. MTAs affect apoptosis signaling pathways by interacting with client pro- teins of interphase microtubules, suggesting that their primary targets are non-tumor cells. The paclitaxel and doxorubicin networks share essential topological axes, suggesting synergistic effects. This may explain the exacerbated toxicity observed when paclitaxel and doxorubicin are used in combination for cancer treatment.

关键词： Cancer treatment Microtubule-targeting agentInteractome analysis Cancer biology Apoptosis

Ultrasound-assisted microfeeding of fine powders

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Particuology 2008年第1期6卷 2-8页

作者： Xuesong Lu Shoufeng Yang julian R.G. Evans Department of Materials Queen Mary University of London Mile End Road London E1 4NS UK

Ultrasonic microfeeding of powders is a new and promising method for use in solid freeforming and pharmaceutical dosing. In this work, computer-controlled microfeeding systems using ultrasonic vibration of a capillary were built. A wide range of controlled, stable rates of flow and switching control were achieved in the acoustic vibration system and uniform powder doses were obtained in the ultrasonic system. Experimental results show that nozzle diameter, transmission fluid depth, waveform, voltage amplitude, frequency and oscillation duration all influence the dose mass. Among these factors, nozzle diameter, voltage amplitude and oscillation duration can be best used to control the dose mass. An artificial neural network （ANN） technique was applied to predict the dose mass. Based on these research results, four types of microfeeding were proposed.

关键词： Microfeeding Ultrasound Fine powders

Designing Pair of Nonlinear Components of a Block Cipher over Gaussian Integers

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Computers, Materials & Continua 2023年第6期75卷 5287-5305页

作者： Muhammad Sajjad Tariq Shah Robinson julian Serna Department of Mathematics Quaid-I-Azam UniversityIslamabad45320Pakistan Escuela de Matemáticas y Estadística Universidad Pedagógica y Tecnológica de ColombiaTunja150003Columbia

In block ciphers,the nonlinear components,also known as sub-stitution boxes(S-boxes),are used with the purpose of inducing confusion in *** the last decade,most of the work on designing S-boxes over the points of elliptic curves has been *** main purpose of these studies is to hide data and improve the security levels of crypto *** this work,we design pair of nonlinear components of a block cipher over the residue class of Gaussian integers(GI).The fascinating features of this structure provide S-boxes pair at a time by fixing three *** the prime field dependent on the Elliptic curve(EC)provides one S-box at a time by fixing three parameters a,b,and *** newly designed pair of S-boxes are assessed by various tests like nonlinearity,bit independence criterion,strict avalanche criterion,linear approximation probability,and differential approximation probability.

关键词： Gaussian integers residue class of gaussian integers block cipher S-boxes analysis of S-boxes

The Black-winged Monarch(Monarcha frater):Geographic variation,taxonomy,a"new"population,and an enduring mystery in migration

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Avian Research 2023年第3期14卷 467-477页

作者： Leo Joseph julian Teh Paul Sweet Phil Gregory Australian National Wildlife Collection CSIRO National Research Collections AustraliaCanberra2601Australia American Museum of Natural History New YorkUSA Sicklebill Safaris TopazQueensland4885Australia

The Black-winged Monarch(Monarcha frater)inhabits low-mid elevation forests across New Guinea and far northeastern *** its four recognized subspecies,*** is migratory,breeding in tropical north-eastern Australia from approximately November–*** non-breeding range of ***,apart from some individuals overwintering in Australia,has been unknown for>100 *** from 194 New Guinean and Australian specimens and a literature review have not solved this mystery;the narrow latitudinal range of the intratropical migration may inhibit use of GPS loggers in resolving the migration *** work in central and western parts of southern New Guinea is *** data,however,revealed an essentially overlooked population in north-western New Guinea east of the Bird's Head Peninsula phenotypically indistinguishable from nominate *** of that *** genomic analysis of the complex will be largely done from toepad skin because frozen tissue samples for DNA analysis exist only of four individuals of what we suggest should be elevated to species rank as *** discuss how genomic analysis might distinguish among alternative taxonomic hypotheses of one,two or three *** suggest English names for what we consider to be three diagnosable taxa worth recognizing at species rank in this group:Arfak Monarch corresponding to ***(Bird's Head Peninsula and the“new”population of north-western New Guinea);Pearly Monarch for ***(Australia and still unknown non-breeding range),and Masked Monarch for ***(including kunupi,elsewhere in New Guinea).

关键词： Australia Migration monarch flycatcher Monarcha frater New Guinea Taxonomy

A bayesian optimisation methodology for the inverse derivation of viscoplasticity model constants in high strain-rate simulations

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Defence Technology（防务技术） 2022年第9期18卷 1563-1577页

作者： Shannon Ryan julian Berk Santu Rana Brodie McDonald Svetha Venkatesh Applied Artificial Intelligence Institute(A^(2)I^(2)) Deakin University75 Pigdons RdWaurn PondsVIC3216Australia Defence Science and Technology Group 506 Lorimer StreetFishermans BendVIC3207Australia

We present an inverse methodology for deriving viscoplasticity constitutive model parameters for use in explicit finite element simulations of dynamic processes using functional experiments, i.e., those which provide value beyond that of constitutive model development. The developed methodology utilises Bayesian optimisation to minimise the error between experimental measurements and numerical simulations performed in LS-DYNA. We demonstrate the optimisation methodology using high hardness armour steels across three types of experiments that induce a wide range of loading conditions: ballistic penetration, rod-on-anvil, and near-field blast deformation. By utilising such a broad range of conditions for the optimisation, the resulting constitutive model parameters are generalised, i.e., applicable across the range of loading conditions encompassed the by those experiments(e.g., stress states, plastic strain magnitudes, strain rates, etc.). Model constants identified using this methodology are demonstrated to provide a generalisable model with superior predictive accuracy than those derived from conventional mechanical characterisation experiments or optimised from a single experimental condition.

关键词： Constitutive modelling Finite element Bayesian optimisation Finite element model updating

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我国医疗设备绩效评价研究的文献计量分析

医学与社会 2024年第8期37卷 52-57,128页

作者：陈菊莲徐玉良裴家旋杨佳艺梅文华乔淑琴珠海市公立医院管理中心广东珠海519000 华中科技大学同济医学院医药卫生管理学院湖北武汉430000 湖北省卫生技术评估研究中心湖北武汉430000 珠海市中西医结合医院广东珠海519000

目的:分析我国医疗设备绩效评价研究的现状和特点,为相关主题的后续研究提供借鉴。方法:检索1984-2022年CNKI数据库收录的医疗设备绩效评价相关文章,运用CiteSpace 5.7R5和VOSviewer 1.6.19对发文量、作者、发文机构、关键词等进行可视... 详细信息

目的:分析我国医疗设备绩效评价研究的现状和特点,为相关主题的后续研究提供借鉴。方法:检索1984-2022年CNKI数据库收录的医疗设备绩效评价相关文章,运用CiteSpace 5.7R5和VOSviewer 1.6.19对发文量、作者、发文机构、关键词等进行可视化分析。结果:共纳入文献1359篇,我国医疗设备绩效评价研究的发文量可分为萌芽期、起步期、爆发期和完善期4个阶段,与国家政策演进间呈现协同关系。研究力量呈现整体分散、局部集中的特点,未形成显著的合作网络。对关键词进行共现、聚类和突现分析发现,研究热点聚焦在大型医疗设备、经济效益、公立医院、风险评估等方面,不同阶段研究侧重点有所不同,从宏观的设备管理、配置评价逐渐延伸到微观的经济效益、设备管理等,后又延伸出效率评价、卫生技术评估等数学模型评价方法或具体维度。结论:我国医疗设备绩效评价领域研究合作网络有待加强,需进一步拓展研究内容、设备的多阶段管理是未来评价研究的新方向。

关键词：医疗设备绩效评价文献计量分析

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人为管控下典型城市空气质量及经济指标特征

环境科学与技术 2024年第S01期47卷 118-126页

作者：周岳屈垚张勇刘卉昆师菊莲朱崇抒中国科学院地球环境研究所黄土与第四纪地质国家重点实验室中国科学院气溶胶化学与物理重点实验室陕西西安710061 中国科学院第四纪科学与全球变化卓越创新中心陕西西安710061 西安地球环境创新研究院陕西西安710061 陕西关中平原区域生态环境变化与综合治理国家野外科学观测研究站陕西西安710061 陕西省大气污染与雾霾防治重点实验室陕西西安710061

为探讨中国典型城市在极端人为源管控条件下空气质量和产业特征,文章分析了2018-2020年1-5月武汉、北京、上海、广州、西安、成都和拉萨等7个城市空气质量及产业发展指标;同比了极端人为管控期大气污染物浓度及经济产业指标变化特征。... 详细信息

为探讨中国典型城市在极端人为源管控条件下空气质量和产业特征,文章分析了2018-2020年1-5月武汉、北京、上海、广州、西安、成都和拉萨等7个城市空气质量及产业发展指标;同比了极端人为管控期大气污染物浓度及经济产业指标变化特征。结果表明:受极端人为管控影响,管控期各污染物浓度同比、环比均出现显著降低,其中NO_(2)浓度环比下降幅度最大,约为50%,其次是PM_(2.5)和PM_(10),百分比为30%~40%。但O_(3)浓度总体呈现上升趋势,未来需进一步采取措施,加强PM_(2.5)和O_(3)协同控制,推动城市空气质量持续改善。各城市不同管控力度对大气污染浓度变化有显著影响。此外,对比了2020年第一和第二季度3类产业发展状况,北京、广州、西安和成都均为第一产业产值恢复速度较快,第三产业增长率最慢为10%;同比3类产业表明管控措施对第二产业影响较大。

关键词：空气质量大气污染特征产业结构人为源管控