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Predicting lumbar Spondylolisthesis: A Hybrid Deep learning Approach

Intelligent Automation & Soft Computing 2023年第8期37卷 2133-2151页

作者： Deepika Saravagi Shweta Agrawal Manisha Saravagi Sanjiv K.Jain Bhisham Sharma Abolfazl Mehbodniya Subrata Chowdhury julian l.webber Department of Computer Application SAGE UniversityIndore452012Madhya PradeshIndia IAC SAGE UniversityIndore452012Madhya PradeshIndia Shivang College of Physiotherapy Ratlam4570021Madhya PradeshIndia Medi-Caps University Rau IndoreMadhya Pradesh453331India Chitkara University Institute of Engineering and Technology Chitkara UniversityPunjabIndia Department of Electronics and Communication Engineering Kuwait College of Science and Technology(KCST)DohaKuwait Department of Computer Science and Engineering Sreenivasa Institute of Technology and Management StudiesChittoorAndra PradeshIndia

Spondylolisthesis is a chronic disease,and a timely diagnosis of it may help in avoiding *** identification in x-ray radiographs is very *** the feature extraction tool in VGG16 has improved the classification *** the fully connected layers of VGG16 are not efficient at capturing the positional structure of an object in *** network(CapsNet)works with capsules(neuron clusters)rather than a single neuron to grasp the properties of the provided image to match the *** this study,an integrated model that is a combination of VGG16 and CapsNet(S-VCNet)is *** the model,VGG16 is used as a feature *** feature extraction,the output is fed to CapsNet for disease identification.A private dataset is used that contains 466 X-ray radiographs,including 186 images displaying a spine with spondylolisthesis and 280 images depicting a normal *** suggested model is the first step towards developing a web-based radiological diagnosis tool that can be utilized in outpatient clinics where there are not enough qualified medical *** results demonstrate that the developed model outperformed the other models that are used for lumbar spondylolisthesis diagnosis with 98%*** the performance check,the model has been successfully deployed on the Gradio web app platform to produce the outcome in less than 20 s.

关键词： Gradio lumbar spondylolisthesis transfer learning VGG16 machine learning deep learning

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Population dynamics of the tropical oyster Magallana bilineata(Mollusca,Bivalvia,Ostreidae)in Mengkabong Bay,Tuaran,Malaysia

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Aquaculture and Fisheries 2024年第2期9卷 295-305页

作者： Joanna W.Doinsing julian Ransangan Politeknik Sandakan Sabah Education HubBatu 10Jalan Sungai BatangSandakanSabah90000Malaysia Borneo Marine Research Institute Universiti Malaysia SabahJalan UMSKota Kinabalu88400Malaysia

Knowledge about the population dynamics within a specific spatial area is vital for the effective planning and management of important fishery *** parameters,including the asymptotic length(l∞),growth coefficient(K),mortalities(Z,F,and M),recruitment pattern,exploitation level(E),and yield per recruit(Y’/R),of the tropical oyster Magallana bilineata in Mengkabong Bay,Tuaran,Malaysia were analyzed by using the FiSAT software,using on the monthly shell length-frequency data collected from April 2019 to March 2020.A total of 435 oysters with shell lengths ranging from 3.64 to 11.16 cm were *** water temperature,salinity,dissolved oxygen,hydrogen ion concentration(pH),and chlorophyll concentration were measured at 29.0-33.7◦C,26.68-35.74 psμ,3.18-6.99 mg/l,6.57-8.29 and 1.51-98.93μg/l,*** logarithmic relationship between the length and weight of log W=1.9055 log l+0.1049(R2=0.5431)with exponent b of 1.9055 for combined sexes showed a negative allometric growth(bluding the use of genetically selected seeds,selection of new farming sites and adoption of grow-out methods that favour high meat *** length(l∞)and growth coefficient(K)of the von Bertalanffy Growth Formula(VBGF)for *** were estimated at 12.13 cm and 1.00 yr􀀀1,*** theoretical ages at length zero(t0)(0.0487)were estimated by substituting l∞and K in Pauly’s *** sizes attained by *** were 3.76,5.04,6.13,7.05,7.83,and 8.49 cm at the end of 2,4,6,8,10,and 12 months,*** calculated growth performance index(φ)for *** in Mengkabong Bay was 2.168,while the estimated lifespan was 3 *** recruitment pattern was observed year-round,with higher recruitment activities in September-October 2019 and January *** total mortality(Z)was analyzed using the length-converted

关键词： Crassostrea iredalei length-weight relationship Growth parameters Recruitment Exploitation

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Quality evaluation of Nothofagus pumilio seeds linked to forest management and climatic events

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Ecological Processes 2024年第1期13卷 98-107页

作者： julian Rodríguez-Souilla Jimena E.Chaves María Vanessa lencinas Juan Manuel Cellini Fidel A.Roig Pablo l.Peri Guillermo Martinez Pastur laboratorio de Recursos Agroforestales Centro Austral de Investigaciones Científicas (CADIC) Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET ) laboratorio de Investigaciones en Maderas (lIMAD) Universidad Nacional de la Plata (UNLP) Instituto Argentino de Nivología Glaciología y Ciencias Ambientales (IAN-IGLA) Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET ) Instituto Nacional de Tecnología Agropecuaria (INTA) Universidad Nacional de la Patagonia Austral (UNPA) Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET )

Background Forest ecosystems undergo significant transformations due to harvesting and climate fluctuations, emphasizing the critical role of seeding in natural regeneration and long-term structural preservation. Climate change further amplifies these dynamics, affecting phenology across species and regions. In Tierra del Fuego(Argentina), Nothofagus pumilio(lenga) forests represent the most important timber resource, and it is managed through different silvicultural strategies. This species demonstrates notable post-disturbance regeneration, yet seed fall exhibits signifi-cant variability, leading to variations in seed quality(e.g., viability). This study aims to assess fluctuations in N. pumilio seed quality, determine how it varies concerning forest management strategies, annual productivity, and the co-occurrence of climatic phenomena including El Ni?o-Southern Oscillation(ENSO) and the Southern Annular Mode(SAM).Results Viable seeds represented 18.4% of the total, notably higher in unharvested than in managed areas. Con-versely, empty seeds were more prevalent in harvested areas(> 75%). Seed quality exhibited significant differences across silvicultural treatments, except for insect-predated seeds, which had similar proportions across all areas, though dispersed retention showed higher predation. When considering years with varying production levels, high-production years favoured full and viable seeds, particularly in unharvested forests and aggregated retention, while low-production years saw reduced viability across all treatments. Quadratic models revealed that viability increased with seed production, where unharvested forests achieved the highest values. Climate variability influenced seed proportions, where ENSO+/SAM+ promoting more full and viable seeds, while ENSO–/SAM+ favoured non-predated seeds, especially in unharvested *** Seed quality varies among treatments and years with different levels of seeding. Variations in seed qual-ity, l

关键词： Forest management Seeding Climate change Extreme event Patagonia

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Prospective cohort study on facial profile changes in infants with Robin sequence and healthy controls

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World Journal of Pediatrics 2024年第6期20卷 581-589页

作者： Cornelia Wiechers julian Sowula Karen Kreutzer Christoph E.Schwarz Christina Weismann Michael Krimmel Christian F.Poets Bernd Koos Department of Neonatology Tuebingen University HospitalCalwerstrasse 772076 TuebingenGermany Center for Cleft lip Palate and Craniofacial MalformationsTuebingen University HospitalTuebingenGermany Department of Orthodontics Tuebingen University HospitalTuebingenGermany Department of Oral and Maxillofacial Surgery Tuebingen University HospitalTuebingenGermany

Background Various conservative and surgical approaches exist to treat Robin sequence(RS),but their effects on facial profile and mandibular catch-up growth are unclear.A functional treatment concept,used in our centre for 25 years,includes an individualized palatal plate with a velo-pharyngeal extension and intensive feeding *** We performed a prospective study to objectively describe facial profiles in infants with RS treated with the above *** with isolated RS were admitted to our tertiary perinatal and national referral centre for craniofacial malformations between May 2018 and Nov *** with RS received 3D-photographs during clinically indicated *** controls were recruited from Dec 2018 to Sep 2019 and received 3D-photographs every 3 *** digitally measured jaw index(JI),defined as alveolar overjet(O)x maxillary arch(U)/mandibular arch(l),and the soft tissue reference points A’-point,Nasion’,B’-point angle(ANB’),describing the relative position of maxilla to mandible,were *** mixed models were used to examine time trajectories in JI and ANB’.Results A total of 2073D images,obtained in 19 infants with RS and 32 controls,were *** and ANB’decreased over time in both groups[for JI−0.18(95%CI−0.25 to−0.10);for ANB’:−0.40°per month[(95%CI−0.48 to−0.32)]]but remained lower in controls[for JI−2.5(95%CI−3.2 to−1.8);for ANB’-1.7°(95%CI−2.4 to−1.0)].Also,the ANB’model showed a significant effect of the interaction term diagnosis x *** Based on longitudinal 3D images,we describe changes in objective parameters of facial profile in infants with and without RS during the first year of *** findings indicate catch-up growth in infants treated for RS.

关键词： Infant Mandibular catch-up growth Pre-epiglottic Baton Plate Robin sequence Three-dimensional photography

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lKB1 depletion-mediated epithelial-mesenchymal transition induces fibroblast activation in lung fibrosis

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Genes & Diseases 2024年第3期11卷 417-426页

作者： Zijian Xu Elizabeth R.Davies liudi Yao Yilu Zhou Juanjuan li Aiman Alzetani Ben G.Marshall David Hancock Tim Wallis julian Downward Rob M.Ewing Donna E.Davies Mark G.Jones Yihua Wang Biological Sciences Faculty of Environmental and Life SciencesUniversity of SouthamptonSouthampton SO171BJUK clinical and Experimental Sciences Faculty of MedicineUniversity of SouthamptonSouthampton SO166YDUK Institute for life Sciences University of SouthamptonSouthampton SO171BJUK NIHR Southampton Biomedical Research Centre University Hospital SouthamptonSouthampton SO166YDUK University Hospital Southampton Southampton SO166YDUK Oncogene Biology The Francis Crick InstituteLondon NW11ATUK

The factors that determine fibrosis progression or normal tissue repair are largely *** previously demonstrated that autophagy inhibition-mediated epithelial-mesenchymal transition(EMT)in human alveolar epithelial type Il(ATIl)cells augments local myofibroblast differentiation in pulmonary fibrosis by paracrine ***,we report that liver kinase B1(lKB1)inactivation in ATIl cells inhibits autophagy and induces EMT as a *** IPF lungs,this is caused by the down-regulation of CAB39l,a key subunit within the lKB1 complex.3D co-cultures of ATIl cells and MRC5 lung fibroblasts coupled with RNA sequencing(RNA-seq)confirmed that paracrine signaling between lKB1-depleted ATIl cells and fibroblasts augmented myofibroblast ***,these data suggest that reduced autophagy caused by lKB1 inhibition can induce EMT in ATIl cells and contribute to fibrosis via aberrant epithelial-fibroblast crosstalk.

关键词： CAB39l Crosstalk EMT lKB1 Pulmonary fibrosis

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A Novel Edge-Assisted IoT-Ml-Based Smart Healthcare Framework for COVID-19

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Computer Modeling in Engineering & Sciences 2023年第12期137卷 2529-2565页

作者： Mahmood Hussain Mir Sanjay Jamwal Ummer Iqbal Abolfazl Mehbodniya julian webber Umar Hafiz Khan Department of Computer Sciences Baba Ghulam Shah Badshah UniversityRajouriJammu&KashmirIndia Department of Computer Sciences National Institute of Electronics and Information TechnologySrinagarJammu&KashmirIndia Department of Electronics and Communication Engineering Kuwait College of Science and TechnologyKuwait City20185145Kuwait Department of Geriatric Medicine Sher-i-Kashmir Institute of Medical SciencesSrinagarJammu&KashmirIndia

The lack of modern technology in healthcare has led to the death of thousands of lives worldwide due to COVID-19 since its *** Internet of Things(IoT)along with other technologies like Machine learning can revolutionize the traditional healthcare *** of reactive healthcare systems,IoT technology combined with machine learning and edge computing can deliver proactive and preventive healthcare *** this study,a novel healthcare edge-assisted framework has been proposed to detect and prognosticate the COVID-19 suspects in the initial phases to stop the transmission of coronavirus *** proposed framework is based on edge computing to provide personalized healthcare facilities with minimal latency,short response time,and optimal energy *** this paper,the COVID-19 primary novel dataset has been used for experimental purposes employing various classification-based machine learning *** proposed models were validated using kcross-validation to ensure the consistency of *** on the experimental results,our proposed models have recorded good accuracies with highest of 97.767%by Support Vector *** to the findings of experiments,the proposed conceptual model will aid in the early detection and prediction of COVID-19 suspects,as well as continuous monitoring of the patient in order to provide emergency care in case of medical volatile situation.

关键词： COVID-19 edge computing framework Internet of Things(IoT) machine learning(Ml) network symptoms

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四大洲食用昼花属的比较入侵生态学:对养分和竞争的响应

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Journal of Plant Ecology 2023年第1期16卷 135-149页

作者： Rubén Portela Rodolfo Barreiro Peter Alpert Cheng-Yuan Xu Bruce l.webber Sergio R.Roiloa BioCost Group Department of BiologyFaculty of ScienceUniversidade da Coruña15071A CoruñaSpain Biology Department University of MassachusettsAmherstMA 01003USA Jepson and University Herbaria University of CaliforniaBerkeleyCA 94709USA School of Health Medical and Applied SciencesCentral Queensland UniversityBundabergQLD 4670Australia CSIRO Health and Biosecurity FloreatWestern Australia 6016Australia School of Biological Sciences The University of Western AustraliaCrawleyWestern Australia 6009Australia Western Australian Biodiversity Science Institute PerthWestern Australia 6000Australia

入侵生物学的两个关键假设是,某些特征是外来物种入侵的基础,且这些特征是在引入期间或之后选择的。我们通过关注两个可能赋予入侵性的特征来检验这些假设,即营养增加引起的较高生长加速和竞争引起的较低生长减速。我们对采自非洲、澳... 详细信息

入侵生物学的两个关键假设是,某些特征是外来物种入侵的基础,且这些特征是在引入期间或之后选择的。我们通过关注两个可能赋予入侵性的特征来检验这些假设,即营养增加引起的较高生长加速和竞争引起的较低生长减速。我们对采自非洲、澳洲、欧洲和北美洲的4个食用昼花属(Carpobrotus)品种进行了比较。为了测试高入侵物种莫邪菊(Carpobrotus edulis)对这些特征的选择,我们将原产于南非的植株与入侵其他3个地区的植株进行了比较。在一个同质园中繁殖植株。然后,在添加或不添加养分的情况下单独培育子代,并在不添加养分的情况下将子代与另一个食用昼花属品种一起、或与欧洲的一种共生本土物种马兰草(Ammophila arenaria)一起培育。不同品种的食用昼花属对营养物质的反应并无差异,在入侵性更强的物种中,竞争反应的负面性也没有减弱。然而,与本土莫邪菊相比,添加营养物质引起外来莫邪菊更高的生长加速。此外,在处理开始时,两种入侵物种每分株的鲜质量高于两种非入侵物种。我们的研究结果表明,引种可以选择入侵物种对营养富集的反应进行选择,也证明了外来植物的体积和入侵性之间的关联。

关键词：食用昼花属海岸沙丘竞争反应外来入侵植物养分有效性快速进化

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Data-driven models for ground and excited states for Single Atoms on Ceria

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npj Computational Materials 2022年第1期8卷 1636-1643页

作者： julian Geiger Albert Sabadell-Rendón Nathan Daelman Núria lópez Institute of Chemical Research of Catalonia(ICIQ) The Barcelona Institute of Science and Technology(BIST)Avinguda Països Catalans 1643007TarragonaSpain Universitat Rovira i Virgili Avinguda Catalunya3543002TarragonaSpain

Ceria-based single-atom catalysts present complex electronic structures due to the dynamic electron transfer between the metal atoms and the semiconductor oxide *** these materials implies retrieving all states in these electronic ensembles,which can be limiting if done via density functional ***,we propose a data-driven approach to obtain a parsimonious model identifying the appearance of dynamic charge transfer for the single atoms(SAs).We first constructed a database of(701)electronic configurations for the group 9–11 metals on CeO_(2)(100).Feature Selection based on predictive Elastic Net and Random Forest models highlights eight fundamental variables:atomic number,ionization potential,size,and metal coordination,metal–oxygen bond strengths,surface strain,and Coulomb *** these variables a Bayesian algorithm yields an expression for the adsorption energies of SAs in ground and low-lying excited *** work paves the way towards understanding electronic structure complexity in metal/oxide interfaces.

关键词： theory excited states

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Multi-tissue transcriptomics of a unique monozygotic discordant twin case of severe progressive osseous heteroplasia

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Genes & Diseases 2024年第3期11卷 22-25页

作者： Alberto Gomez-Carballa Maria Jose Curras-Tuala Sara Pischedda Miriam Cebey-lopez Jose Gomez-Rial Irene Rivero-Cale Jacobo Pardo-seco Xabier Bello Sandra Viz-lasheras Antonio Justicia-Grande julian Montoto-louzao Alba Camino-Mera Isabel Ferreiros-Vidal Maximo Fraga Jose RAntunez Rodolfo Gomez Federico Martinon-Torres Antonio Salas Genetics Vaccines and Infections Research Group(GENVIP)Instituto de Investigacion Sanitaria de SantiagoSantiagode CompostelaGalicia 15706Spain Translational Pediatrics and Infectious Diseases Department of PediatricsHospital Clinico Universitario de Santiago de CompostelaServicio Galego de Saude(SERGAS)Galicia 15706Spain laboratorio de Inmunologia Servicio de Andlisis ClinicosHospital Clinico Universitario de Santiago de CompostelaServicio Galego de Saude(SERGAS)Galicia 15706Spain Unidade de Xenetica Instituto de Ciencias Forenses(INCIFOR)Facultade de MedicinaUniversidade de Santiago de Compostelaand GenPoB Research GroupInstituto de Investigacion SanitariaHospital Clinico Universitario de Santiago de CompostelaServicio Galego de Saude(SERGAS)Galicia 15706Spain Musculoskeletal Pathology Group Instituto de Investigacion Sanitaria de SantiagoServicio Galego de Saude(SERGAS)Santiago de CompostelaGalicia 15706Spain Department of Pathology Hospital Clinico Universitario de Santiago de Compostela(SERGAS)Galicia 15706Spain Unidad Integrada de BiobancosBiomodelos 3D y Modelos Animales IDIS(lnstituto de Investigacion Sanitaria de Santiagode Compostela)Galicia15706Spain Centro de Investigacion Biomedica en Red de Enfermedades Respiratorias(CIBER-ES) MadridSpain

Progressive osseous heteroplasia(POH)is an ultra-rare autosomal dominant disabling disorder characterized by heterotopic ossification(HO).It is caused by heterozygous inactivating mutations in the GNAS(guanine nucleotide-binding protein alpha-stimulating activity polypeptide)***,the molecular mechanisms underlying HO remain poorly *** a treatment for POH is not yet available,the identification of the mechanisms driving POH in affected tissues using gene expression may be of great help to underestand the molecular basis of POH and develop new therapeutic approaches.

关键词： stimulating driving asi

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lost in translation: Evaluating traditional Chinese medicine by western standards

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Pediatric Investigation 2022年第2期6卷 144-146页

作者： Cynara S.leon julian l.Allen The Children’s Hospital of Philadelphia and the Perelman School of Medicine the University of PennsylvaniaPhiladelphiaPennsylvaniaUSA

In this issue of Pediatric Investigation,Xu et al.'reporl a study comparing two medications w ith immunomodulatory properties in the treatment of pediatric recurent respiratory tract infections(RRTI).Pidotimod is a synthetic dipeptide introduccd in the 1990s.2 while Yupingfeng(YPF)is a traditional Chinese medicine(TCM).TCM has roots as early as the 14th century *** the west,it certainly has its skepics.

关键词： roots modulator

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