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Magnetic resonance imaging appearance and changes on intracavitary Gliadel wafer placement:A pilot study

World Journal of Radiology 2011年第11期3卷 266-272页

作者： Rivka R Colen Pascal O Zinn Saman Hazany Daniel Do-Dai julian k wu kevin Yao Jay J Zhu Department of Radiology Brigham and Women's HospitalBostonMA 02115United States Department of Neurosurgery Beth Israel Deaconess Medical CenterBostonMA 02215United States Department of Radiation Oncology Dana Farber Cancer InstituteBostonMA 02115United States Department of Radiology Beth Israel Deaconess Medical CenterBostonMA 02215United States Department of Neuroradiology Tufts Medical CenterBostonMA 02115United States Department of Neurosurgery Tufts Medical CenterBostonMA 02115United States Mischer Neuroscience Associates UT Houston and Memorial Hermann HospitalHoustonTX 77030United States

AIM:To investigate changes on magnetic resonance imaging(MRI) which occur with intracavitary Gliadel wafer placement in patients with glioblastoma multiforme(GBM).METHODS:This retrospective Health Insurance Portability and Accountability Act-compliant study was approved by the institutional review board,with a waiver of informed consent.A total of eight patients aged 29-67 years with GBM underwent Gliadel wafer placement.T2-weighted/FLAIR images and post-contrast T1-weighted images both before and after wafer placement were retrospectively reviewed in consensus to determine changes in the following parameters:appearance of the pericavitary tissue,pattern of tumor recurrence or progression and appearance of the Gliade lwafer ***:Five out of the eight patients had a progressive increase in enhancement and pericavitary T2/FLAIR hyperintensity within the first 2 mo and a subsequent decrease in these MRI *** ofthese patients had tumor recurrence within the first6 *** out of the eight patients demonstrated aprogressive increase in enhancement and pericavitary T2 hyperintensity,which continued after the first 6 mo,and were subsequently diagnosed with true tumor *** was no increase in distant/nonlocal tumor *** Gliadel wafer appearance changed over ***:Pseudoprogression is common after intracavitary Gliadel wafer placement and thus care should be taken before diagnosing tumor progression or recurrence within the first 2 mo.

关键词： Pseudoprogression Gliadel wafers Glioblastoma Local chemotherapy Glioma

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重复荷载作用后海工高性能混凝土梁刚度退化试验研究

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土木与环境工程学报（中英文） 2024年第3期46卷 171-179页

作者：陆春华吴小龙蔡启明张菊连江苏大学土木工程与力学学院江苏镇江212013 上海宏信建筑科技有限公司上海201800

在荷载长期作用下,钢筋混凝土受弯构件的变形是一个重要的评价指标,也是构件正常使用极限状态的验算内容之一。为了研究经历重复荷载后海工高性能混凝土梁的变形发展规律,设计制作了10根试验梁,分别进行了重复荷载试验、氯盐干湿试验以... 详细信息

在荷载长期作用下,钢筋混凝土受弯构件的变形是一个重要的评价指标,也是构件正常使用极限状态的验算内容之一。为了研究经历重复荷载后海工高性能混凝土梁的变形发展规律,设计制作了10根试验梁,分别进行了重复荷载试验、氯盐干湿试验以及两者的共同作用试验;通过四点受弯试验对梁的跨中挠度及刚度退化进行评价,提出了梁短期刚度规范计算公式的修正方法。研究结果表明:荷载水平按梁纯弯段弯矩等于0.4M_(u)确定时,施加30次重复荷载后混凝土的损伤度接近15%;对于仅进行氯盐干湿循环的试验梁,其跨中挠度发展要慢于参照梁;施加重复荷载后,试验梁的跨中挠度发展要快于参照梁;对施加重复荷载后的试验梁再进行氯盐干湿循环,梁的刚度退化更为显著。结合试验结果,采用损伤效应折减系数对梁短期刚度计算公式进行修正,并验证了修正公式的合理性和有效性。

关键词：重复荷载海工混凝土梁损伤度氯盐环境弯曲刚度

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Asian Urban Environment and Climate Change: Preface

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Journal of Environmental Sciences 2017年第9期29卷 1-5页

作者： julian Hunt Jianping wu University College London and Trinity College University of Cambridge School of Civil Engineering Tsinghua University

The Asian Network on Climate Science and Technology （***）, in collaboration with Tsinghua University, held a conference on environmental and climate science, air pollution, urban planning and transportation in July 2015, with over 40 Asian experts participating and presentation. This was followed by a meeting with local government and community experts on the practical conclusions of the conference. Of the papers presented at the conference a selection are included in this special issue of ]ournal of Environmental Science, which also reflects the conclusions of the Paris Climate meeting in Dec 2015, when the major nations of the world agreed about the compelling need to reduce the upward trend of adverse impacts associated with global climate change. Now is the time for urban areas to work out the serious consequences for their populations, but also how they should work together to take action to reduce global wanning to benefit their own communities and also the whole planet!

关键词： Urban transportation

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Outage-driven link selection for secure buffer-aided networks

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Science China(Information Sciences) 2022年第8期65卷 197-212页

作者： Dawei WANG Tianmi HE Fuhui ZHOU julian CHENG Ruonan ZHANG Qihui wu School of Electronics and Information Northwestern Polytechnical University College of Electronic and Information Engineering Nanjing University of Aeronautics and Astronautics National Mobile Communications Research Laboratory Southeast University School of Engineering The University of British Columbia Research & Development Institute of Northwestern Polytechnical University in Shenzhen key Laboratory of Dynamic Cognitive System of Electromagnetic Spectrum Space Nanjing University of Aeronautics and Astronautics

In this paper, we investigate secure communication in a two-hop wireless network, where multiple buffer-aided relays assist to securely forward data from the sender to the destination threatened by a passive eavesdropper. To satisfy the security and delay requirements, we propose a novel link selection policy without the instantaneous wiretap channel state information. Different from the most current link selection policies,the proposed link selection policy is designed by joint considering the link secrecy outage probability and the buffer states. To evaluate the secrecy performance, we first characterize the system state transition matrix and the stationary state probability, and then derive the closed-form expressions for the secrecy outage probability and the secrecy rate. Moreover, we formulate a framework based on the queuing theory to analyze the end-to-end information delay at the source, the relays, and the queues, and derive the closed-form expression for the information delay. Finally, we conduct simulations to validate our theoretical performance analysis, and verify the performance improvement of the proposed outage-driven secure transmission scheme in terms of secrecy outage probability and information delay.

关键词： buffer-aided relay information delay link selection secrecy outage probability

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Variant selection in laser powder bed fusion of non-spherical Ti-6Al-4V powder

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Journal of Materials Science & Technology 2023年第16期147卷 56-67页

作者： Mohammadreza Asherloo Ziheng wu julian E.C.Sabisch Iman Ghamarian Anthony D.Rollett Amir Mostafaei Department of Mechanical Materials and Aerospace EngineeringIllinois Institute of Technology10 W 32nd StreetChicagoIL 60616United States Materials Engineering Division Lawrence Livermore National Laboratory7000 East AveLivermoreCA 94550United States Samuel Roberts Noble Microscopy Laboratory University of OklahomaNormanOK 73019United States School of Aerospace and Mechanical Engineering University of OklahomaNormanOK 73019United States Department of Materials Science and Engineering Carnegie Mellon UniversityPittsburghPA 15213United States

The presence ofα/αon priorβ/βgrain boundaries directly impacts the final mechanical properties of the titanium ***β/βgrain boundary variant selection of titanium alloys has been assumed to be unlikely owing to the high cooling rates in laser powder bed fusion(L-PBF).However,we hypothesize that powder characteristics such as morphology(non-spherical)and particle size(50–120μm)could affect the initial variant selection in L-PBF processed Ti-6Al-4V alloy by locally altering the cooling *** the high cooling rate found in L-PBF,results showed the presence ofβ/βgrain boundaryαlath growth inside two adjacent priorβ*** backscatter diffraction micrographs confirmed the presence ofβ/βgrain boundary variant selection,and synchrotron X-ray high-speed imaging observation revealed the role of the“shadowing effect”on the locally decreased cooling rate because of keyhole depth reduction and the consequentβ/βgrain boundaryαlath *** self-accommodation mechanism was the main variant selection driving force,and the most abundantα/αboundary variant was type 4(63.26°//[10553¯]).The dominance of Category IIαlath clusters associated with the type 4α/αboundary variant was validated using the phenomenological theory of martensite transformations and analytical calculations,from which the stress needed for theβ→αtransformation was calculated.

关键词： Variant selection Phase formation Additive Manufacturing Hydride-dehydride powder Texture analysis Electron backscattered diffraction

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Taxonomic synopsis of Berberis(Berberidaceae)from the northern Hengduan mountains region in China,with descriptions of seven new species

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Plant Diversity 2022年第5期44卷 505-517页

作者： Yao-ke Li julian Harber Chuan Peng Zhi-Qiang Du Yao-wu Xing Chih-Chieh Yu CAS key Laboratory of Tropical Forest Ecology Xishuangbanna Tropical Botanical GardenChinese Academy of SciencesMenglaYunnan666303China University of Chinese Academy of Sciences Beijing100049China Research Associate Missouri Botanic GardenMytholmroydWest YorkshireUK Center of Plant Ecology Core Botanical GardensChinese Academy of SciencesMenglaYunnan666303China

Though Berberis(Berberidaceae)is widely distributed across the Eurasian landmass it is most diverse in the Himalaya-Hengduan Mountain(HHM)*** are more than 200 species in China where it is one of the most common mountain *** study on the taxonomy and evolution of Berberis in this region can thus provide an important insight into the origin and diversification of its flora.A prerequisite to this is mapping and describing the various species of Berberis in the region-a task that despite recent progress is by no means *** is clear that in China there may be a significant number of species still to be described and that even with published species much about their distribution remains to be *** a contribution to the first of these tasks seven new species from the northern Hengduan Mountain of *** and ***:Berberis chinduensis,Berberis degexianensis,Berberis jiajinshanensis,Berberis jinwu,Berberis litangensis,Berberis longquensis and Berberis riparia,are described *** in overall morphology and especially in floral structures with each other and with similar species of Berberis in the same region are *** report is the result of phylogenetic analyses based on plastome and partial nrDNA sequences of both the seven proposed new species and a significant number of similar species already *** conclusions as to the insights provides on the history of the genetic divergence are discussed.

关键词： Berberidaceae Flora of China Herbarium taxonomy Plastome sequences nrDNA sequences

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中药膏摩砭石熨摩治疗1例脾虚湿阻型胃痞患者的护理体会

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中西医结合护理 2024年第5期10卷 47-51页

作者：王晓鸽皇菊莲毕守红吴转转山西中医药大学山西晋中030606 山西中医药大学附属医院脾胃病科山西太原030024

本文总结中药膏摩砭石熨摩治疗1例脾虚湿阻型胃痞患者的护理体会。基于护理评估和中医辨证,在生活指导、饮食护理等常规护理基础上,根据患者的临床表现,采用中药膏摩砭石熨摩、手指点穴等中医护理干预,能够有效改善患者的消化功能,促进... 详细信息

本文总结中药膏摩砭石熨摩治疗1例脾虚湿阻型胃痞患者的护理体会。基于护理评估和中医辨证,在生活指导、饮食护理等常规护理基础上,根据患者的临床表现,采用中药膏摩砭石熨摩、手指点穴等中医护理干预,能够有效改善患者的消化功能,促进早期康复。

关键词：功能性消化不良胃痞中药膏摩砭石熨摩中医护理

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Cytosolic Ca^2＋ Signals Enhance the Vacuolar Ion Conductivity of Bulging Arabidopsis Root Hair Cells

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Molecular Plant 2015年第11期8卷 1665-1674页

作者： Yi Wang julian Dindas Florian Rienmuller Melanie krebs Rainer Waadt karin Schumacher Wei-Hua wu Rainer Hedrichl M. Rob G. Roelfsema Molecular Plant Physiology and Biophysics Julius-von-Sachs Institute for Biosciences Biocenter Werzburg University Julius-von-Sachs-Platz 2 97082Wurzburg Germany State key Laboratory of Plant Physiology and Biochemistry (SkLPPB) College of Biological Sciences China Agricultural University Beijing 100193 China Centre for Organismal Studies Developmental Biology of Plants University of Heidelberg Im Neuenheimer Feld 230 69120 Heidelberg Germany College of Science King Saud University (KSU) Riyadh Saudi Arabia

Plant cell expansion depends on the uptake of solutes across the plasma membrane and their storage within the vacuole. In contrast to the well-studied plasma membrane, little is known about the regulation of ion transport at the vacuolar membrane. We therefore established an experimental approach to study vacuolar ion transport in intact Arabidopsis root cells, with multi-barreled microelectrodes. The subcellular position of electrodes was detected by imaging current-injected fluorescent dyes. Comparison of measurements with electrodes in the cytosol and vacuole revealed an average vacuolar membrane potential of -31 inV. Voltage clamp recordings of single vacuoles resolved the activity of voltage-independent and slowly deactivating channels. In bulging root hairs that express the Ca2＋ sensor R-GECO1, rapid elevation of the cytosolic Ca^2＋ concentration was observed, after impalement with microelectrodes, or injection of the Ca^2＋ chelator BAPTA. Elevation of the cytosolic Ca^2＋ level stimulated the activity of voltage- independent channels in the vacuolar membrane. Likewise, the vacuolar ion conductance was enhanced during a sudden increase of the cytosolic Ca^2＋ level in cells injected with fluorescent Ca^2＋ indicator FURA-2. These data thus show that cytosolic Ca^2＋ signals can rapidly activate vacuolar ion channels, which may prevent rupture of the vacuolar membrane, when facing mechanical forces.

关键词： electrophysiology ion channels calcium signaling/transport fluorescence imaging Arabidopsis,vacuolar membrane

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Drivers of East Asian summer monsoon variability:Global oceans and the Tibetan Plateau

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Science Bulletin 2024年第16期69卷 2487-2490页

作者： Anmin Duan Guoxiong wu Bin Wang Andrew G.Turner Jun Hu Wenting Hu Ping Zhang Die Hu Yuheng Tang Center for Marine Meteorology and Climate Change State Key Laboratory of Marine Environmental ScienceCollege of Ocean and Earth SciencesXiamen UniversityXiamen 361102China State key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics(LASG) Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China Department of Atmospheric Sciences School of Ocean and Earth Science and TechnologyUniversity of HawaiiHonolulu 96822USA Department of Meteorology University of ReadingReading RG67BEUK

The East Asian summer monsoon(EASM)profoundly influences the hydroclimate,ecosystems,and water resources of a densely populated region in *** EASM can lead to floods,droughts,significant economic losses,and social disruption in East Asia and Southeast *** the Indian and African monsoons,the EASM is shaped by both tropical and extratropical climate systems,including tropical oceanic modes,cross-equatorial airflows,the Madden-julian Oscillation,the thermal condition of the Tibetan Plateau,the South Asia High,and the mid-latitude westerly jet.

关键词： Tibetan monsoon East

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Genomic Shift in Population Dynamics of mcr-1-positive Escherichia coli in Human Carriage

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Genomics, Proteomics & Bioinformatics 2022年第6期20卷 1168-1179页

作者： Yingbo Shen Rong Zhang Dongyan Shao Lu Yang Jiayue Lu Congcong Liu Xueyang Wang Junyao Jiang Boxuan Wang Congming wu julian Parkhill Yang Wang Timothy R.Walsh George F.Gao Zhangqi Shen College of Veterinary Medicine China Agricultural UniversityBeijing 100193China Guangdong Laboratory for Lingnan Modern Agriculture Guangzhou 510641China CAS key Laboratory of Pathogenic Microbiology and Immunology Institute of MicrobiologyChinese Academy of SciencesBeijing 100101China The Second Affiliated Hospital of Zhejiang University School of Medicine Zhejiang UniversityHangzhou 310009China Department of Veterinary Medicine University of CambridgeCambridge CB30ESUK Department of Biology University of OxfordOxford OX13SZUK Chinese Center for Disease Control and Prevention Beijing 102206China

Emergence of the colistin resistance gene,mcr-1,has attracted worldwide *** the prevalence of mcr-1-positive Escherichia coli(MCRPEC)strains in human carriage showing a significant decrease between 2016 and 2019,genetic differences in MCRPEC strains remain largely *** therefore conducted a comparative genomic study on MCRPEC strains from fecal samples of healthy human subjects in 2016 and *** identified three major differences in MCRPEC strains between these two time ***,the insertion sequence ISApl1 was often deleted and the percentage of mcr-1-carrying IncI2 plasmids was increased in MCRPEC strains in ***,the antibiotic resistance genes(ARGs),aac(3)-IVa and blaCTX-M-1,emerged and coexisted with mcr-1 in ***,MCRPEC strains in 2019 contained more virulence genes,resulting in an increased proportion of extraintestinal pathogenic ***(ExPEC)strains(36.1%)in MCRPEC strains in 2019 compared to that in 2016(10.5%),implying that these strains could occupy intestinal ecological niches by competing with other commensal *** results suggest that despite the significant reduction in the prevalence of MCRPEC strains in humans from 2016 to 2019,MCRPEC exhibits increased resistance to other clinically important ARGs and contains more virulence genes,which may pose a potential public health threat.

关键词： Colistin mcr-1 Escherichia coli Genomics Human

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