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Enabling Virtual Met Masts for wind energy applications through machinelearning-methods

能源与人工智能(英文) 2023年第1期11卷 26-42页

作者： Sandra Schwegmann Janosch Faulhaber Sebastian Pfaffel Zhongjie Yu Martin Dörenkämper Kristian Kersting julia Gottschall Fraunhofer IWES Küpkersweg 7026129 OldenburgGermany Fraunhofer IEE Königstor 5934119 KasselGermany Technical University of Darmstadt Karolinenplatz 564289 DarmstadtGermany Hessian Center for AI(hessian.AI) Mornewegstraße 3064293 DarmstadtGermany

As wind is the basis of all wind energy projects, a precise knowledge about its availability is needed. For ananalysis of the site-specific wind conditions, Virtual Meteorological Masts (VMMs) are frequently used. VMMsmake use of site calibrated numerical data to provide precise wind estimates during all phases of a wind energyproject. Typically, numerical data are used for the long-term correlation that is required for estimating theyield of new wind farm projects. However, VMMs can also be used to fill data gaps or during the operationalphase as an additional reference data set to detect degrading sensors. The value of a VMM directly dependson its ability and precision to reproduce site-specific environmental conditions. Commonly, linear regressionis used as state of the art to correct reference data to the site-specific conditions. In this study, a frameworkof 10 different machine-learning methods is tested to investigated the benefit of more advanced methods ontwo offshore and one onshore site. We find significantly improving correlations between the VMMs and the reference data when using more advanced methods and present the most promising ones. The K-NearestNeighbors and AdaBoost regressors show the best results in our study, but Multi-Output Mixture of GaussianProcesses is also very promising. The use of more advanced regression models lead to decreased uncertainties;hence those methods should find its way into industrial applications. The recommended regression models canserve as a starting point for the development of end-user applications and services.

关键词： Virtual Met Mast(VMM) Wind power Machine learning Reanalysis data Site assessment Weather Research and Forecasting Model(WRF) Measure-Correlate-Predict(MCP)

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Calmodulin Bound Aquaporin-0 Reveals Two Distinct Energy Profiles

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Computational Molecular Bioscience 2016年第4期6卷 66-79页

作者： l. K. Balcziak T. H. bach l. R. Montgomery M. E. Warwick U. Akgun Physics Department Coe College Cedar Rapids IA USA

Aquaporin-0 (AQP0) contributes to the nurturing and cleaning of the eye lens of waste products. It is a tetrameric protein composed of four identical monomers, each of which has its own water pore. AQP0 water conduction is regulated by pH, Ca2+ concentration, and the phosphorylation of serine residues at the C-terminal. High cellular Ca2+ concentration enhances the binding of Calmodulin (CaM), a Ca2+ dependent protein, to AQP0 from cytoplasm. This study focuses on determining the differences between the AQP0-CaM and the open AQP0 systems, by using Molecular Dynamics (MD) methods. The water conduction energy profiles are measured with two separate MD simulation techniques revealed two distinct channel profiles for the AQP0-CaM combined model. While the CaM bound channels’ energy barriers exceed the 6 kcal/mol, the no CaM bound AQP0 energy profile stays below 3 kcal/mol. The structural analysis of these different pores during the free equilibrations also supported this conclusion with distinct pore diameters. Unlike the previous report, this study observed Phe75 and His66 taking role in stabilizing the CSII restriction site in CaM bound AQP0.

关键词： Aquaporin-0 Calmodulin Water Channel MD Simulations

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Theoretical study of defect impact on two-dimensional MoS

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Journal of Semiconductors 2015年第12期 22-27页

作者： Anna V.Krivosheeva Victor l.Shaposhnikov Victor E.Borisenko Jean-louis lazzari Chow Waileong julia Gusakova Beng Kang Tay Belarusian State University of Informatics and Radioelectronics CNRS Aix-Marseille Université NOVITAS Nanoelectronics Centre of Excellence School of Electrical and Electronic Engineering Nanyang Technological University CINTRA CNRS NTUTHALES Nanyang Technological University

Our theoretical findings demonstrate for the first time a possibility of band-gap engineering of monolayer MoS;crystals by oxygen and the presence of vacancies. Oxygen atoms are revealed to substitute sulfur ones, forming stable MoS;O;ternary compounds, or adsorb on top of the sulfur atoms. The substituting oxygen provides a decrease of the band gap from 1.86 to 1.64 eV and transforms the material from a direct-gap to an indirect-gap semiconductor. The surface adsorbed oxygen atoms decrease the band gap up to 0.98 eV depending on their location tending to the metallic character of the electron energy bands at a high concentration of the adsorbed atoms. Oxygen plasma processing is proposed as an effective technology for such band-gap modifications.

关键词： two-dimensional crystal molybdenum disulfide band gap vacancy oxygen

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Orchomenella pinguis(amphipoda)-a possible species for heavy metal biomonitoring of marine sediments

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Journal of Coastal life Medicine 2014年第2期2卷 116-123页

作者： lis bach laura Ferguson Vilhelm Feltelius Jens Sondergaard Department of Bioscience–Arctic Research Centre(ARC) Aarhus UniversityFrederiksborgvej 3994000 RoskildeDenmark Arctic Technology Centre ARTEK-Department of Civil EngineeringTechnical University of DenmarkKemitorvetBuilding 2042800 Kgs.LyngbyDenmark Heriot-Watt University RiccartonEdinburghEH141ASScotlandUnited Kingdom Department of Earth Sciences Uppsala UniversityVillavägen 16 B75236 UppsalaSweden

Objective:To evaluate the potential local benthic biomonitor organism,Orchomenella pinguis(***),for mining contamination by addressing accumulation and toxicity of mining related metals in this arctic marine ***:A toxicity study exposed *** to four commonly occurring heavy metals(Cd,Cu,Zn and Pb)associated to the mining industry in Greenland using:1)a 5-day water-only bioassay;2)a water-only bioassay evaluating the response between metal accumulation in *** and metal concentrations in water during a 5-day period;and finally 3)a sediment bioassay evaluating the response between metal accumulation in *** and metal concentrations in sediment as a function of time during a 20-day period using different mixtures of mining-contaminated ***:lC_(50)values for the four metals were 2.8,5.4,10.4 and 21.4μmol/l,for Cu,Cd,Pb and Zn,respectively,with corresponding modelled metal concentrations of 3.4,1.0,11.1 and 6.1μmol/g dry *** the sediment exposure experiments,a similar concentration of Zn did not induce lethal effects at the same ***:This study demonstrates that the appliance of metal organism concentrations as an estimate of effects is not a sufficient biomonitor of environmental *** organism may sequester metals into cellular compartments thus rendering the metals inert for toxic *** studies are needed to investigate effects of metal *** biomarkers such as effects on functional responses *** and burial behavior or effects on reproductive success are suggested in order enhance to the ecological significance.

关键词： Invertebrate Heavy metals Water-only bioassay Sediment bioassay Accumulation Greenland

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临床全视野视网膜电图标准

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中华眼科杂志 2020年第9期56卷 662-669页

作者：无 McCulloch D.l. Marmor Michael F. Brigell Mitchell G. Hamilton Ruth Holder Graham E. Tzekov Radouil bach Michael 国际临床视觉电生理学会 School of Optometry and Vision Sciences University of WaterlooWaterlooCAN 不详

本标准由国际临床视觉电生理学会(ISCEV)制定并修订,旨在提出临床全视野视网膜电图(ERG)检测的ISCEV最新意见。本次修订的主要内容是修改了标准刺激闪光的参数,以适应各种不同光源(包括气体放电灯和发光二极管灯)的刺激器;规定了基于明... 详细信息

本标准由国际临床视觉电生理学会(ISCEV)制定并修订,旨在提出临床全视野视网膜电图(ERG)检测的ISCEV最新意见。本次修订的主要内容是修改了标准刺激闪光的参数,以适应各种不同光源(包括气体放电灯和发光二极管灯)的刺激器;规定了基于明适应和暗适应下不同刺激闪光强度引发的6种ERG反应(即6种检测方案),同时ISCEV也鼓励使用其他全视野ERG检测扩展方案。

关键词：气体放电灯发光二极管灯刺激器暗适应标准刺激闪光强度检测方案 ERG

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Anatomical structure of Aconitum napellus over ground part and subterranean organs

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中国中药杂志 2010年第5期35卷 579-582页

作者： Tatiana l Kiseleva Ekaterina Y ladyiguina larisa N Frolova Nina N Melnikova Elena V Tsvetayeva julia A Smirnova Homeopathy and Naturopathy Institute of Federal Scientific Clinico-experimental Center for Traditional Diagnostics Methods and Cure Under Ministry of Health of the Russian Federation Moscow

Aconite or monkshood is various and counts as many as 300 *** types can be distinguished by color of flowers,flower galea heights,number of follicles and mostly,by their root system[1].Aconitum *** to napellus section... 详细信息

关键词：解剖学根状菌束临床分析症状

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η-production on the proton via electromagnetic and hadronic probes

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Chinese Physics C 2009年第12期33卷 1175-1182页

作者： B. Saghai J. Durand B. julia-Diaz 何军 T.-S. H. lee T. Sato Institut de Recheche sur les lois Fondamentales de l’Univers DSM/Irfu CEA-Saclay 91191 Gif-sur-Yvette France 2. Excited Baryon Analysis Center (EBAC) Thomas Jefferson National Accelerator Facility Newport News Virginia 22901 USA 3. Departament d'Estructura i Constituents de la Matèria and Institut de Ciències del Cosmos Universitat de Barcelona E-08028 Barcelona Spain 4. Institute of Modern Physics Chinese Academy of Sciences Physics Division Argonne National Laboratory Argonne Illinois 60439 USA Department of Physics Osaka University Toyonaka Osaka 560-0043 Japan

The reactions π-p→ηn and γp→ηp are investigated within a dynamical coupled-channels model of meson production reactions in the nucleon resonance region. The meson-baryon channels included are πN, ηN, π-, σN, and ρN. The direct η-photoproduction process is studied within a formalism based on a chiral constituent quark model approach, complemented with a one-gluon-exchange mechanism, to take into account the breakdown of the SU(6)O(3) symmetry. In the models search, the following known nucleon resonances are embodied: S11(1535), S11(1650), P11(1440), P11(1710), P13(1720), D13(1520), D13(1700), D15(1675), and F15(1680). Data for the π-p→ηn reaction from threshold up to a total center-of-mass energy of W ≈ 2 GeV are satisfactorily reproduced. For the photoproduction channel, two additional higher mass known resonances, P13(1900) and F15(2000), are also considered. However, reproducing the data for γp→ηp requires, within our approach, two new nucleon resonances, for which we extract mass and width.

关键词： multichannel scattering meson production baryon resonances

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Stem cell-based therapy for human diseases

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Signal Transduction and Targeted Therapy 2022年第9期7卷 3242-3282页

作者： Duc M.Hoang Phuong T.Pham Trung Q.bach Anh T.l.Ngo Quyen T.Nguyen Trang T.K.Phan Giang H.Nguyen Phuong T.T.le Van T.Hoang Nicholas R.Forsyth Michael Heke liem Thanh Nguyen Department of Research and Development Vinmec Research Institute of Stem Cell and Gene TechnologyVinmec Healthcare SystemHanoiVietnam Department of Cellular Therapy Vinmec High.Tech CenterVinmec Healthcare SsystemHanoiVietnam Institute for Science&Technology in Medicine Keele UniversityKeeleUK a Department of Biology Stanford UniversityStanfordCAUSA

Recent advancements in stem cell technology open a new door for patients suffering from diseases and disorders that have yet to be *** cell-based therapy,including human pluripotent stem cells(hPsCs)and multipotent mesenchymal stem cells(MSCs),has recently emerged as a key player in regenerative *** are defined as self-renewable cell types conferring the ability to differentiate into various cellular phenotypes of the human body,including three germ *** are multipotent progenitor cells possessing self-renewal ability(limited in vitro)and differentiation potential into mesenchymal lineages,according to the International Society for Cell and Gene Therapy(ISCT).This review provides an update on recent clinical applications using either hPSCs or MSCs derived from bone marrow(BM),adipose tissue(AT),or the umbilical cord(UC)for the treatment of human diseases,including neurological disorders,pulmonary dysfunctions,metabolic/endocrine-related diseases,reproductive disorders,skin burns,and cardiovascular ***,we discuss our own clinical trial experiences on targeted therapies using MsCs in a clinical setting,and we propose and discuss the MSC tissue origin concept and how MSC origin may contribute to the role of MSCs in downstream applications,with the ultimate objective of facilitating translational research in regenerative medicine into clinical *** mechanisms discussed here support the proposed hypothesis that BM-MSCs are potentially good candidates for brain and spinal cord injury treatment,AT-MSCs are potentially good candidates for reproductive disorder treatment and skin regeneration,and UC-MsCs are potentially good candidates for pulmonary disease and acute respiratory distress svndrometreatment.

关键词： diseases distress treatment

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Hepatic flow is an intraoperative predictor of early allograft dysfunction in whole-graft deceased donor liver transplantation: An observational cohort study

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World Journal of Hepatology 2019年第9期11卷 689-700页

作者： Pablo lozano lominchar Maitane Igone Orue-Echebarria lorena Martín Cristina julia lisbona María Magdalena Salcedo luis Olmedilla Hemant Sharma Jose Manuel Asencio JoséAngel lópez-Baena General Surgery Department Liver Transplant UnitHospital General Universitario Gregorio MaranonMadrid 28007Spain Anesthesiology Department Liver Transplant UnitHospital General Universitario Gregorio MaranonMadrid 28007Spain Hepatology Department Liver Transplant UnitHospital General Universitario Gregorio MaranonMadrid 28007Spain Department of Transplant Surgery Oschner Medical CenterNew OrleansLA 70816United States

BACKGROUND Early allograft dysfunction(EAD)after liver transplantation(lT)is an important cause of morbidity and *** ensure adequate graft function,a critical hepatocellular mass is required in addition to an appropriate blood *** hypothesized that intraoperative measurement of portal venous and hepatic arterial flow may serve as a predictor in the diagnosis of *** To study whether hepatic flow is an independent predictor of EAD following *** This is an observational cohort study in a single *** arterial blood flow and portal venous blood flow were measured intraoperatively by transit *** was defined using the Olthoff *** and multivariate analyses were used to determine the intraoperative predictors of *** analysis and prognostic factor analysis were performed using the Kaplan-Meier and Cox regression *** A total of 195 liver transplant procedures were performed between January 2008 and December 2014 in 188 patients.A total of 54(27.7%)patients developed *** median follow-up was 39 *** venous flow,hepatic arterial flow(HAF)and total hepatic arterial flow were associated with EAD in both the univariate and multivariate *** is an independent prognostic factor for 30-d patient *** Intraoperative measurement of blood flow after reperfusion appears to be a predictor of EAD;Moreover,HAF should be considered a predictor of 30-d patient mortality.

关键词： Hepatic flow Early allograft dysfunction liver transplant

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现代身体

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2018年

作者： (美)朱莉娅·l. 福克斯(julia l. Foulkes)

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