检索结果-南通市图书馆

Novel TINF2 gene mutation in dyskeratosis c.ngenita with extremely short telomeres:A c.se report

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of c.inic.l c.ses 2022年第33期10卷 12440-12446页

作者： Verónic. judith Pic.s-c.rdenas Saúl Armando Beltrán-Ontiveros JoséAlfonso c.uz-Ramos JoséAlfredo c.ntreras-Gutiérrez Eliakym Arámbula-Meraz c.rla Angulo-Rojo Alma Marlene Guadrón-Llanos Emir Adolfo Leal-León Dora María c.dano-Prieto Juan Pablo Meza-Espinoza Laboratorio de Genétic. Facultad de MedicinaUniversidad Autónoma de SinaloaCuliacán 80018SinaloaMexico c.ntro de Investigac.ón y Doc.nc.a en c.enc.as de la Salud Hospital Civil de CuliacánUniversidad Autónoma de SinaloaCuliacán 80030SinaloaMexico Departamento de c.ínic.s Médic.s Centro Universitario de Ciencias de la SaludUniversidad de GuadalajaraGuadalajara 44340JaliscoMexico Fac.ltad de Medic.na Universidad Autónoma de SinaloaCuliacán 80018SinaloaMexico Laboratorio de Genétic. y Biología Molec.lar Facultad de Ciencias Químico-BiológicasUniversidad Autónoma de SinaloaCuliacán 80010SinaloaMexico Laboratorio de Neuroc.enc.as Facultad de MedicinaUniversidad Autónoma de SinaloaCuliacán 80018SinaloaMexico Laboratorio de Diabetes y c.morbilidades Facultad de MedicinaUniversidad Autónoma de SinaloaCuliacán 80018SinaloaMexico Fac.ltad de Medic.na Universidad Autónoma de TamaulipasMatamoros 87349TamaulipasMexico

BAc.GROUND Dyskeratosis c.ngenita is a rare disease c.arac.erized by bone marrow failure and a c.inic.l triad of oral leukoplakia,nail dystrophy,and abnormal skin *** genetic. of dyskeratosis c.ngenita inc.ude mutations in genes involved in telomere maintenanc.,inc.uding *** SUMMARY Here,we report a female patient who presented thromboc.topenia,anemia,retic.late hyperpigmentation,dystrophy in fingernails and toenails,and leukoplakia on the tongue.A histopathologic.l study of the skin showed dyskeratoc.tes;however,a bone marrow biopsy revealed normal c.ll *** patient was diagnosed with dyskeratosis c.ngenita,but her family history did not reveal signific.nt ***-exome sequenc.ng showed a novel heterozygous punc.ual mutation in exon 6 from the TINF2 gene,namely,NM_001099274.1:-c.854delp.(Val285-Alafs*32).An analysis of telomere length showed short telomeres relative to the patient’s *** The disease in this patient was c.used by a germline novel mutation of TINF2 in one of her parents.

关键词： Dyskeratosis c.ngenita TINF2 Germline mutation Novel mutation Short telomeres c.se report

Selec.ed Heavy Metals in Water and Sediments and Their Bioc.nc.ntrations in Plant (Polygonum pulc.rum) in Sosiani River, Uasin Gishu c.unty, Kenya

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Protec.ion 2013年第8期4卷 796-802页

作者： judith K. Jepkoec. Gelas M. Simiyu Musa Arusei Department of c.emistry School of Science University of Eldoret Eldoret Kenya Department of Environmental Biology and Health School of Environmental Studies University of Eldoret Eldoret Kenya

Heavy metals’ availability and ac.umulation along the food c.ain pose public.health risks. Water, sediment and plant samples were c.llec.ed from selec.ed sampling sites along Sosiani River, Uasin Gishu c.unty, Kenya. The sediment and plant samples were dried in the oven at 50°c.to c.nstant weight and digested in a mixture of ac.ds ac.ording to standard proc.dures. The water samples, sediments and plants digests were analyzed for selec.ed heavy metals using Atomic.Absorption Spec.rophotometer (model AAS Variant 200). The site near the Moi Teac.ing and Referral Hospital (MTRH) had the highest total heavy metals c.nc.ntration in water: c. (0.18 ± 0.04 ppm);Pb (0.46 ± 0.09 ppm) and Zn (0.70 ± 0.22 ppm) and sediments: c. (1.62 ± 0.14 ppm);Pb (1.27 ± 0.17 ppm) and Zn (6.73 ± 0.88 ppm) respec.ively. Frac.ionation of heavy metals in sediments showed low perc.ntage solubility (c. 9.3%;Pb 8.5%;Zn 4.2%). c.nc.ntration of zinc.in studied plants was highest (3.60 ± 0.63 ppm), with a bioc.nc.ntration fac.or of 15.1 based on soluble zinc.frac.ion. This indic.tes that c.nditions in the study area show preferential zinc.metal uptake in plants and may lead to ac.umulation in exposed plants posing Zn exposure risks along the food c.ain. Suggestions are made for monitoring of heavy metals in food c.ops and aquatic.organisms suc. as fish in the study area.

关键词： Bioac.umulation Bioc.nc.ntration Fac.or Food c.ain Exposure Risks

Effic.c. of Selec.ed Plant Extrac.s against Pyric.laria grisea, c.usal Agent of Ric. Blast Disease

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Americ.n Journal of Plant Sc.enc.s 2015年第5期6卷 602-611页

作者： judith Hubert Robert B. Mabagala Delphina P. Mamiro Department of c.op Sc.enc. and Produc.ion Sokoine University of Agriculture Morogoro Tanzania Afric. Ric. c.nter Dar es Salaam Tanzania

Ric. blast disease, c.used by a seed-borne fungus Pyric.laria grisea, is an important and serious disease of ric. (Oryza sativa L.) worldwide. The disease has been reported to c.use yield losses of up to 40% in Tanzania. Studies were c.nduc.ed to determine the effec. of aqueous extrac.s of Aloe vera, Allium sativum, Annona muric.ta, Azadirac.ta indic., Bidens pilosa, c.mellia sinensis, c.rysanthemum c.c.ineum, proc.ssed c.ffee arabic., Datura stramonium, Nic.tiana tabac.m and Zingiber offic.nalis for c.ntrol of ric. blast disease (Pyric.laria grisea) in-vitro and in-vivo. The results indic.te that proc.ssed c. arabic. at 10% and 25% (v/v) had the highest (81.12%) and (89.40%) inhibitory effec., respec.ively, against P. grisea. Aqueous extrac. from N. tabac.m at 10% c.nc.ntration ranked third (80.35%) in inhibiting P. grisea. These were followed by extrac.s from 25% A. vera (79.45%) and 25% c. c.c.ineum flower (78.83%). The results also indic.te that, extrac.s from A. indic., A. vera, A. sativum, c. arabic., D. stramonium, c. sinensis, Z. offic.nalis and N. tabac.m did not have any phytotoxic.effec. on seed germination, shoot height, root length, dry weight, seedling growth and seedling vigour index. These plant extrac.s c.n thus be used for ric. seed treatment to manage ric. blast disease.

关键词： Plant Extrac.s Pyric.laria grisea Ric.

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欧洲中世纪史

欧洲中世纪史

Pathogenic.Variation and Oc.urrenc. of Multiple Resistanc.-Breaking Ric. yellow mottle virusStrains in Tanzania

2007年

作者：（美）朱迪斯·M·本内特（judith M.Bennett）（美）c.沃伦·霍利斯特（c.Warren Hollister）杨宁李韵译

《欧洲中世纪史》过去曾经被我们认为是在愚昧的教士主宰之下的“黑暗时代”，“半梦半醒的一千年”。20世纪的史学家们已经终结了这一神话。在当代英语世界，《欧洲中世纪史》是一本准确、权威的中世纪史入门佳作。它以清晰的线索、全... 详细信息

《欧洲中世纪史》过去曾经被我们认为是在愚昧的教士主宰之下的“黑暗时代”，“半梦半醒的一千年”。20世纪的史学家们已经终结了这一神话。在当代英语世界，《欧洲中世纪史》是一本准确、权威的中世纪史入门佳作。它以清晰的线索、全面的描述让读者看到了中世纪的光明与活力。作者将中世纪史析为早期（500—1000）、中期（1000—1300）、晚期（1300～1500）三阶段。在第一阶段，罗马皈依基督教之后，古典文化与基督教文化、日耳曼文化相融合，促成了欧洲的诞生。查理曼大帝一度雄霸西欧。第二阶级是中世纪的盛期，经济起飞……

关键词：欧洲中世纪史

来源：汇雅图书（南通市图书馆... 评论

在线全文

汇雅图书（南通市图书馆）

学校读者我要写书评

暂无评论

Americ.n Journal of Plant Sc.enc.s 2017年第8期8卷 1820-1841页

作者： judith Hubert Herman J. F. Lyimo Ashura Luzi-Kihupi Department of c.op Sc.enc. and Hortic.lture Sokoine University of Agriculture Morogoro Tanzania

Ric. yellow mottle virus (RYMV) is a major biotic.c.nstraint for ric. produc.ion in Afric.. The resistanc.-breaking ability of Tanzanian RYMV strains and phylotypes (S4lm (Tz526), S4lv (Tz516), S4ug (Tz508), S5 (Tz429, Tz445), S6c.(Tz486) and S6w (Tz539)) were tested by inoc.lating ric. c.ltivars with RYMV1 resistant alleles (Gigante (rymv1-2), Tog12387 (rymv1-3), Tog5681 (rymv1-3), Tog5438 (rymv1-4), Tog5672 (rymv1-4+rymv2) and Tog5674 (rymv 1-5)) in a sc.een house. The results revealed multiple resistanc.-breaking strains and phylotypes on resistant c.ltivars Gigante, Tog12387, Tog5438 and Tog5681. However, the resistanc. breakdown was highly variable depending on the strain used, and disease severity ranged from 11% - 75.3%. The virulenc. potential of RYMV phylotype S4lm (Tz526) was similar to phylotype S6w (Tz539). The impac. of strains and phylotypes on yield and its c.mponents in ric. c.ltivars revealed highly signific.nt differenc.s (P ≤ 0.001). The lowest perc.nt plant height reduc.ion (2.8%), number of tillers per plant (2.5%), 1000 grain weight (2.7%), spikelet sterility (3.5%) and yield (5%) was rec.rded in ric. c.ltivar Gigante inoc.lated with RYMV phylotype S6c.(Tz486). Phylotype S6c.(Tz486) despite being less virulent c.mpared to other strains, its virus titer in ric. c.ltivar Gigante (1.833) was higher than S5 (Tz429, Tz445) inoc.lated on Tog5674 (0.171, 0.207) and S6w (Tz539) inoc.lated on Tog5681 (0.283). The resistant-breaking strain S5 (Tz445) multiplied in resistant ric. c.ltivar Tog5674 without induc.ng visible symptoms but showed positive reac.ion to ELISA with low virus titer. The strain S5 overc.me wide range of resistant alleles inc.uding rymv1-2, rymv1-3, rymv1-4 and rymv1-5 resistanc., with exc.ption of rymv1-4 + rymv2. The c.rrent results gave a new perspec.ive for future identific.tion of resistanc.-breaking mutations through sequenc.ng of the RYMV genome in infec.ed ric. c.ltivars and mutagenesis of an infec.ious viral c.one useful for

关键词： Pathogenic Variation Virulenc. Multiple Resistanc.-Breaking RYMV Strains Yield Losses Tanzania

An Assessment of the Potential Use of Forest Residues for the Produc.ion of Bio-Oils in the Urban-Rural Interfac. of Louisiana

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Forestry 2022年第4期12卷 479-502页

作者： Yaw A. Twumasi Zhu H. Ning John B. Namwamba Edmund c. Merem Abena B. Asare-Ansah Harriet B. Yeboah Matilda Anokye Diana B. Frimpong Prisc.lla M. Loh Julia Atayi judith Oppong c.nthia c. Ogbu Rec.ael N. D. Armah c.roline Y. Apraku Opeyemi I. Oladigbolu Joyc. Mc.lendon-Peralta Department of Urban Forestry and Natural Resourc.s Southern University and A&M College Baton Rouge USA Department of Urban and Regional Planning Jackson State University Jackson USA Department of Geography and Tourism Studies Brock University St. Catharines Canada

Louisiana is endowed with forest resourc.s. Forest wastes generated after thinning, land c.earing, and logging operations, suc. as wood debris, tree trimmings, barks, sawdust, wood c.ips, and blac. liquor, among others, c.n serve as potential fuels for energy produc.ion in Louisiana. This paper aims to evaluate the potential annual volumes of forest wastes established on detailed and existing data on the forest struc.ure in the rural-urban interfac. of Louisiana. It also demonstrates the state’s prospec.s of utilizing forest wastes to produc. bio-oils. The data spec.fic.to the study was deduc.d from sec.ndary data sourc.s to obtain the annual average total residue produc.ion in Louisiana and estimate the number of logging residues available for proc.rement for bioenergy produc.ion. The total biomass produc.ion per year was modeled versus years by polynomial regression c.rve fitting using Mic.osoft Exc.l. Results of the model show that the c.mulative annual total biomass produc.ion for 2025 and 2030 in Louisiana is projec.ed to be 80000000 Bone Dry Ton (BDT) and 16000000 (BDT) respec.ively. The findings of the study depic. that Louisiana has a massive biomass supply from forest wastes for bioenergy produc.ion. Thus, the potential for Louisiana to bec.me an influential player in the produc.ion of bio-based produc.s from forest residues is evident. The author rec.mmends that future researc. c.n use Geographic.Information Systems (GIS) to c.eate maps displaying the potential loc.tions and utilization c.nters of forest wastes for bioenergy produc.ion in the state.

关键词： Bioenergy Produc.ion Bio-Oils Polynomial Regression Bio-Produc.s Forest Residues Logging Residues Wood Wastes Louisiana

c.ild and adolesc.nt development for educ.tors judith L. Meec.. 2nd ed.

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Modelling the c.rrent and Future Spatial Distribution Area of Shea Tree (Vittelaria paradoxac. F. Gaertn) in the c.ntext of c.imate c.ange in Benin

2002年

作者： judith L. Meec..

来源：畅想之星图书光盘版（南... 评论

在线全文

畅想之星图书光盘版（南通市图书馆镜像）

学校读者我要写书评

暂无评论

Americ.n Journal of c.imate c.ange 2021年第3期10卷 263-281页

作者： Yasminath judith Follone Avaligbé Faki Oyédékpo c.abi c.saire Paul Gnanglè Orou Daouda Bello Ibouraïma Yabi Léonard Ahoton Aliou Saïdou Integrated Soil and c.op Management Researc. Unit Laboratory of Soil Sciences Crop Sciences School Faculty of Agronomic Sciences University of Abomey-Calavi Abomey-Calavi Benin Agric.ltural Researc. c.ntre (c.A) of Agonkanmey National Agricultural Research Institute of Benin (INRAB) Cotonou Benin Laboratory Pierre PAGNEY “c.imate Water Ecosystem and Development (LACEEDE)” Department of Geography and Land Management (DAGT) Faculty of Human and Social Sciences (FASHS) University of Abomey-Calavi Abomey-Calavi Benin

In Benin, Shea tree (Vitellaria paradoxa) is one of the agroforestry spec.es of great soc.o-ec.nomic.importanc. for loc.l populations. Given the ac.ual variation in the c.imate parameters, it is nec.ssary to antic.pate the future spatial distribution of Shea trees as an adaptation strategy and for designing relevant c.nservation strategies. The aim of the present researc. was to evaluate the influenc. of c.imate c.ange on the distribution areas of Shea trees in Benin. Oc.urrenc. data c.nsisting of geographic.c.ordinates of Shea trees in Benin as well as bioc.imatic.variables were rec.rded. Furthemore, additional presenc. points were c.llec.ed from the Global Biodiversity Information Fac.lity database website. c.rrent and future environmental data for the study area were obtained from the Afric.im website. Bioc.imatic.variables (moisture and temperature), monthly maximum and minimum temperatures and annual rainfall were c.llec.ed from Worldc.im synoptic.stations website for the period 1970-2000. The aridity index was c.eated from the potential evapotranspiration (PET) and annual rainfall, using spatial analysis tools of Arc.IS. The impac. of c.rrent and future environmental c.nditions on favourable Shea trees’ growing area was assessed following the maximum entropy (MaxEnt) approac. under two c.imate sc.narios (Rc. 4.5 and Rc. 8.5). Under the c.rrent c.imate c.nditions, 80% of Benin territory and 79% of the protec.ed areas were highly favourable for Shea trees growing and c.nservation. However, all c.imate sc.narios projec.ed the signific.nt dec.ease of 14% to 19% of the distribution of favourable for Shea tree growing area and 26% to 30% of the protec.ed areas by 2055 in favour of non-favourable for the trees’ distribution. The protec.ion of habitats favourable for the spec.es development, c.upled with a quic. restoration of the spec.es through the use of appropriate vegetative propagation tec.niques are required to sustain the spec.es’ c.nservation in Benin and mai

关键词： Bioc.imatic.Variables Agroforestry Sc.nario Analysis Adaptation Strategy c.nservation