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Foliar Analysis as an Estimate on the Nutritional State of Conilon Coffee Plantations on Cambisoils

Journal of Life Sciences 2014年第2期8卷 181-187页

作者： Alberto Perez Diaz Emesto Castaneda Hidalgo Salvador Lozano trejo Carlos Alberto Bustamante Gonzailez Ramon Antonio Rivera Espinosa Geraldo rodriguez Ortiz Gloria Martha Martin Alonso Cerelino RoblesPerez Guillermo Acosta Coutin Alberto Fernandez Turro Centro de Estudios de Cafe y Cacao Universidad de Guantanamo Guantanamo 95300 Cuba Instituto Tecnologico del Valle de Oaxaca Ex Hacienda de Nazareno Xoxocotlan 712320 Mexico Instituto de Investigaciones Agroforestales UCTB-Tercer Frente Santiago de Cuba 92700 Cuba Instituto Nacional de Ciencias Agricolas San Jose de las Lajas Mayabeque 32700 Cuba Universidad de Ciencias Pedagogicas "Raul Gomez Garcla " Guantanamo 95100 Cuba

The objective of this paper relies on the establishment of the sampling moment and the nutritional state of the species Conilon coffee （Coffea canephora） cultivated in Cambisoils. The effect of different rates of nitrogen fertilization was also studied in the leaves concentrations of N, at randomized complete block designs （N0= 0; N1 = 50; N2 = 100; N3 = 150 and N4 = 200 ***^-1 of N） in presence of P （40 ***^-1 of P2O5） and K （160 ***^-1 of K2O）, with four replicates. The samples were carried out in the months of March （flower blossoming stage）, June （fruits growing stage）, September （grain development） and December （maturation） in all treatments. Foliar analysis carried out in the month of June （fruits growing stage） for the purpose of establishing critical nutrient range values for N, settling down approaches of interpretation of the same one for the Conilon coffee plantations on Cambisoils. The biggest percentages in the yields are obtained with leaves containing N between 2.80% and 3.10%, a value below 2.80% N which they associated with indicative percentages of stable maximum yield that did not surpass the limits of the adequate nutrients supply.

关键词： Nitrogen fertilization critical nitrogen range Conilon coffee leaves concentrations of N.

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Estimate of the Crystallization Kinetics in Stoichiometry Compositions Films of Ge:Sb:Te

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Journal of Surface Engineered Materials and Advanced Technology 2012年第1期2卷 44-46页

作者： Carlos Virgilio Rivera rodriguez Eduardo Morales Sanchez Jesus Gonzalez Hernandez Evgen Prokhorov juan Munoz Saldana Gerardo Trapaga Martinez Ciencias Ambientales del Instituto Nacional de Investigaciones Nucleares La MarquesaMexico CICATA-IPN Unidad Queretaro QueretaroMexico Centro de Investigacion en Materiales Avanzados ChihuahuaMexico CINVESTAV-Qro. QueretaroMexico

The aim of this work is to compare the isothermal crystallization kinetic in the films along GeTe-Sb2Te3 line with composition Ge2Sb2Te5, Ge1Sb2Te4 Ge1Sb4Te7 and Ge4Sb1Te5 using mainly Johnson–Mehl–Avrami-Kolmogorov (JMAK) model. Results obtained have shown different crystallization mechanism in the investigated films. In Ge2Sb2Te5 and Ge1Sb2Te4 films the analysis of the kinetic results (Avrani coefficient) showed that at the beginning of crystallization a metastable phase appeared with the Ge1Sb4Te7 composition, this is followed by the nucleation and growth of the stable fcc phase up to full crystallization. In contrast Ge4Sb1Te5 and Ge1Sb4Te7 films show diffusion control growing from small dimension grains with decreasing nucleation rate.

关键词： Crystallization Ge:Sb:Te JMAK Model

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特乌拉达市政礼堂双城系

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城市环境设计 2013年第8期 88-99页

作者：弗朗西斯科·曼加多 juan rodriguez Roland Halbe

特乌拉达-莫莱拉是一个不同寻常的市中心。尽管它被划分为两个独立的物理单元,但却属于同一个行政主体。场地位于阿里坎特,一处由山脉向大海倾斜的山谷处,城市充分利用陆地和海洋两个实体,定义了建筑环境,充当视觉向导。作为新的城市开... 详细信息

特乌拉达-莫莱拉是一个不同寻常的市中心。尽管它被划分为两个独立的物理单元,但却属于同一个行政主体。场地位于阿里坎特,一处由山脉向大海倾斜的山谷处,城市充分利用陆地和海洋两个实体,定义了建筑环境,充当视觉向导。作为新的城市开发项目的一部分,市政礼堂从特拉乌达拔地而起,位于城市海拔较高的地块上。从这一点,越过散落着小小的白色建筑间的山谷,人们可以看到海边的莫莱拉小镇。独一无二的场地位置使建筑成为连接两个城市中心的桥梁。两个中心虽然就物理位置而言是彼此分离的,但两者的领地、景观和文化

关键词：场地位置建筑礼堂公共建筑莫莱

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Socioeconomic Aspects for Coastal Mollusk Commercial Fishing in Costa Chica,Guerrero,Mexico

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Natural Resources 2018年第6期9卷 229-241页

作者： Lizeth Galeana-Rebolledo Rafael Flores-Garza juan Violante-Gonzalez Pedro Flores-rodriguez Sergio Garcia-Ibanez Victor Landa-Jaime Arcadio Valdes-Gonzalez Centro de Ciencias de Desarrollo Regional Pino s/n.Col.El RobleAcapulcoMéxico Facultad Ecologia Marina Gran Via TropicalN°20Fraccionamiento Las PlayasAcapulcoMexico Departamento de Estudios para el Desarrollo Sustentable de Zonas Costeras San Patricio-MelaqueMexico Facultad de Ciencias Biologicas Universidad Autonoma de Nuevo LeonCiudad UniversitariaSan Nicolas de los GarzaMexico

An important part of the fishing activity in Mexico is carried out in the coastal strip and has a strong social, economic and ecological importance. In the state of Guerrero, mollusks fishing is coastal and craftwork activity focused on a small number of species and without information on biology and reproductive or ecological aspects for most species caught. This research was carried out in the Costa Chica region, Guerrero, Mexico and the aims were: 1) To analyze the socioeconomic features of cooperative societies of fishing production;and 2) To know the diversity of mollusks caught by coastal fishing and the species that have the greatest importance in fishing. From February to April 2013-2015, seven fish coop units, four piers and places where seafood is sold were visited. For the socio-economic analysis and the determination of the species that have more importance in the coastal fishing, a total of 67 surveys were applied. In order to determine the cast of species, the specimens captured by the fishermen were used, which were identified and counted. A total of 67 interviews were analyzed and an average of $1806.00 was estimated as weekly economic income just as a product of fishing, it was also estimated that on average the fishermen work 4.3 days a week. Fisheries cooperatives market most of their produce directly to restaurateurs and locals on the piers. Replacement of older adults by young fishermen from the same region was observed, most are adults between 22 and 39 years old. 25 species of mollusks of economic importance were registered for the coastal fishermen of the Costa Chica. Six species were identified as the main target for catching fishermen. The fishing of mollusks in Costa Chica is not subject to any type of control, which has led to overfishing reflected in the decline sizes and banks in populations of commercial importance.

关键词： Molluscs Coastal Fishing Socioeconomic Fisherman

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Isolation,Identification and Germplasm Preservation of Different Native Spirulina Species from Western Mexico

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American Journal of Plant Sciences 2013年第12期4卷 65-71页

作者： Rout Nutan Prasad Khandual Sanghamitra Gutierrez-Mora Antonia Gallardo-Valdéz juan rodriguez-Garay Benjamin Ibarra-Montoya JLuis Vega-Valero Guillermo Centro de Investigación y Asistencia en Tecnología y Diseno del Estado de Jalisco A.C.Av.Normalistas#800Colinas de la NormalGuadalajaraJaliscoMexico Biotecnología Mexicana de Microalgas S.A.de C.V.Sta.Maria 136 Conlonia TepeyacZapopanJaliscoMexico

Spirulina is an edible algae and has a wide range of pharmaceutical applications in addition to its nutritional value. Isolation and identification of several Spirulina species were conducted in the western part of Mexico especially in the state of Jalisco. The purification strategy consisted of five optimized processing steps: 1) washing and centrifugation, 2) chemical treatment, 3) micromanipulation, 4) serial dilution, and 5) plating. Four species were isolated from different locations and two out of these four species were identified taxonomically up to the species level: Spirulina subsalsa and S. major. For short term conservation (30 days), the strains were maintained in liquid and solid agar medium at 10?C and 4?C. For medium term (few months), they were preserved in solid medium under a dried condition as agar flakes and for long term, cryopreservation was employed by using 5% and 10% DMSO, glycerol and methanol as osmoprotectants in liquid nitrogen. For short term preservation nearly 90% liquid and 100% agar recovered strains were viable after one month at both temperatures. In the case of the agar flakes, cells were viable after three months of conservation at room temperature. Cryopreservation did not give any suitable results after three months of conservation. Variable and two-step improved cryopreservation processes are now in progress for conservation.

关键词： Germplasm Cryopreservation Spirulina Long Term Preservation

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Convective drying of yellow discarded onion (Angaco INTA): Modelling of moisture loss kinetics and effect on phenolic compounds

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Information Processing in Agriculture 2020年第2期7卷 333-341页

作者： Marıa Celia Roman Maria Paula Fabani Lorena Celina Luna Gabriela Egly Feresin German Mazza Rosa rodriguez Instituto de Ingeniera Quımica-Grupo Vinculado al PROBIEN(CONICET-UNCo) Facultad de IngenierıaUniversidad Nacional de San JuanArgentina Instituto de Biotecnologıa Facultad de IngenierıaUniversidad Nacional de San JuanArgentina Instituto de Investigacio´n y Desarrollo en Ingenierıa de Procesos Biotecnologı´a y Energı´as AlternativasCONICET-Universidad Nacional del ComahueNeuquenArgentina

The Angaco INTA onion variety is the most cultivated and its production,mostly is destined for *** to their high-quality standards of these markets,many onions are *** drying process seems to be a promising solution that not only give added value to this product,but also extend shelf *** this work,the influence of convective drying process,at 60 and 70C,on the kinetic behavior,antioxidant activity,phenolic and flavonoid contents of discarded onion slices were *** that,the Angaco INTA onion is a variety genetically developed to have shorter cultivation times in this region;the phenolic compounds content in this onion variety,the drying kinetics and its influence on this content have never been *** this study,the phenolic compounds contributions to dehydrated product quality was evaluated,observing that the convective drying increased the total soluble phenolic and flavonoid contents and antioxidant properties for both temperatures,being highest at 70*** rehydration ratios were similar to the slices dried at 60 and 70*** models were used for describing the obtained drying curve equation of onion slices,being the Midilli’s model the one that presented the best ***’s model of water diffusion fitted all experimental data with acceptable correlation *** the achieved findings,70C is the optimum temperature to produce the dehydrated Angaco INTA onion.

关键词： Drying Antioxidant activity Phenolic content Kinetic model

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The human olfactory system in two proteinopathies: Alzheimer’s and Parkinson’s diseases

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Translational Neurodegeneration 2020年第2期9卷 270-289页

作者： Isabel Ubeda-Bañon Daniel Saiz-Sanchez Alicia Flores-Cuadrado Ernesto Rioja-Corroto Melania Gonzalez-rodriguez Sandra Villar-Conde Veronica Astillero-Lopez juan Pablo Cabello-de la Rosa Maria Jose Gallardo-Alcañiz Julia Vaamonde-Gamo Fernanda Relea-Calatayud Lucia Gonzalez-Lopez Alicia Mohedano-Moriano Alberto Rabano Alino Martinez-Marcos Neuroplasticity and Neurodegeneration Laboratory Ciudad Real Medical SchoolCRIBUniversity of Castilla-La Mancha13005Ciudad RealSpain Neurology Service Ciudad Real General University Hospital13005Ciudad RealSpain Pathology Service Ciudad Real General University Hospital13005Ciudad RealSpain Faculty of Health Sciences University of Castilla-La ManchaTalavera de la ReinaSpain Neuropathology Department and Tissue Bank CIEN FoundationCarlos III Health InstituteMadridSpain

Alzheimer’s and Parkinson’s diseases are the most prevalent neurodegenerative *** etiologies are idiopathic,and treatments are symptomatic and orientated towards cognitive or motor ***,both are proteinopathies with pathological aggregates(plaques of amyloid-β peptide and neurofibrillary tangles of tau protein in Alzheimer’s disease,and Lewy bodies mostly composed of α-synuclein in Parkinson’s disease).These deposits appear in the nervous system in a predictable and accumulative sequence with six neuropathological *** disorders present a long prodromal period,characterized by preclinical signs including ***,the olfactory system,particularly the anterior olfactory nucleus,is initially and preferentially affected by the *** atrophy revealed by magnetic resonance imaging must be complemented by histological analyses to ascertain whether neuronal and/or glial loss or neuropil remodeling are responsible for volumetric *** has been proposed that these proteinopathies could act in a prion-like manner in which a misfolded protein would be able to force native proteins into pathogenic folding(seeding),which then propagates through neurons and glia(spreading).Existing data have been examined to establish why some neuronal populations are vulnerable while others are resistant to pathology and to what extent glia prevent and/or facilitate proteinopathy *** approaches reveal a number of hubs in the olfactory system(anterior olfactory nucleus,olfactory entorhinal cortex and cortical amygdala)that are key interconnectors with the main hubs(the entorhinal–hippocampal–cortical and amygdala–dorsal motor vagal nucleus)of network dysfunction in Alzheimer’s and Parkinson’s diseases.

关键词： α-Synuclein Amyloid-β Anterior olfactory nucleus Hyposmia Tau protein

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A Comparative Study for Successful Treatment per Gender in a Specialized Smoking Cessation Unit in the Albacete University Hospital during Two Years

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Journal of Health Science 2015年第3期3卷 103-112页

作者： Francisco Javier Callejas Gonzalez Genoves Crespo Marta Cruz Ruiz Javier Esquinas Lopez Cristina Tarraga Lopez Pedro juan Pablo Bermejo Lopez Tornero Molina Ana Isabel Pastrana Calderon juan Molina Cano Angel rodriguez Montes Jose Antonio Pneumonology Department The Albacete University Hospital Complex (CHUA) Albacete 02006 Spain Thoracic Surgery Department The Albacete University Hospital Complex (CHUA) Albacete 02006 Spain Pneumonology Department Vall d'Hebron University Hospital Barcelona 08035 Spain Integrated Care Management The Albacete University Hospital Complex (CHUA) Albacete 02006 Spain College of Computer Engineering Castilla-La Mancha University (UCLM) Albacete 02071 Spain General and Digestive Surgery Department La Paz University Hospital Madrid 28046 Spain

Objective： Analysis of abstinence rates of smokers per gender at 3, 6, 9 and 12 months in a Smoking Cessation Unit from January 2008 to December 2009. Methods： Descriptive retrospective study. Analysis of socio-demographic variables, smoking patterns, associated comorbidities, continuous abstinence rates, success, relapses, failure and dropping out. Results： 278 smokers started treatment （33%）; 55.4% males and 44.6% females （mean age of 48.3 and 44.06 years, respectively）. The main associated comorbidities were： psychiatric （38.7%）, cardiovascular （dyslipemia 25%） and respiratory （COPD （chronic obstructive pulmonary disease） 9.7%） in females; cardiovascular （dyslipemia 34.4%）, psychiatric （34.4%） and respiratory （COPD 19.5%） in males. VRN （Varenicline） was prescribed in 40.2% males and 32.2% females; NRT （nicotine replacement therapy） was used in 46.6% and 38.7%, respectively; bupropion was employed in 6.5% and 21.8%, respectively. Psychological counseling was offered only to 7.8% males and 8.1% females. The continuous abstinence rates in males at 3, 6, 9 and 12 months were 51.3%, 37.7%, 32.5% and 30.5%, respectively, and were 45.2%, 29.8%, 25.0% and 24.2% for females. Failure was 9.7% for females and 18.8% for males. Success was more frequent for those on VRN （n = 41 males; n = 12 females）. No relapses were indicated for 42 females and 71 males. The percentage of relapses was higher at 3 months （29.0% females, 19.5% males）. Conclusions： The study observed differences in treating abstinence between genders （in the abstinence rates and failure index）. This implies having to consider incorporating the gender variable into the diagnosis, treatment and prevention of smoking.

关键词： Smoking smoking cessation gender continuous abstinence successful treatment failure relapse

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IMT504: A New and Potent Adjuvant for Rabies Vaccines Permitting Significant Dose Sparing

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World Journal of Vaccines 2012年第4期2卷 182-188页

作者： Alejandro D. Montaner Analia De Nichilo juan M. rodriguez Andres Hernando-Insua juan Fló Ricardo A. Lopez Verónica Sierra Claudio Paolazzi Oscar Larghi David L. Horn Jorge Zorzopulos Fernanda Elias David Horn LLC Doylestown PA USA. Immunotech S.A. Buenos Aires Argentina Instituto de Investigaciones Biomédicas Fundación Pablo Cassará Buenos Aires Argentina Instituto San Jorge Bagó Buenos Aires Argentina Instituto San Jorge Bagó Buenos Aires Argentina. nstituto de Investigaciones Biomédicas Fundación Pablo Cassará Buenos Aires Argentina

Background: Rabies virus infection causes encephalitis, which is almost always fatal. Vaccination can be extremely effective at preventing disease but is prohibitively costly. Vaccine formulations allowing dose-sparing and fewer inoculations with faster antibody response would be extremely desirable. IMT504, an immunostimulatory non-CpG oligo-deoxynucleotide, is a highly potent vaccine adjuvant. Methods: Human and rat antibody measurements, and rat chal-lenge studies were performed. Results: In rats, highly effective immune responses with IMT504 were observed even after diluting vaccine up to 1/625. In highly lethal, live intracerebral rabies challenge studies, protection occurred even with extremely dilute vaccine plus IMT504. In humans, antibody titers developed faster and were significantly higher with IMT504-adjuvanted diluted vaccine vs non-adjuvanted vaccine (full strength or diluted). All five administered IMT504-adjuvanted diluted vaccine reached protective antibodies (≥0.5 IU/ml) after the second injection. After the third injection, individuals receiving IMT504-adjuvanted diluted vaccine reached levels approximately 10 times higher than controls (M ± SEM: 31.0 ± 10.9 vs 3.40 ± 0.99 IU/ml). Conclusions: These data suggest that IMT504 may allow fewer inoculations, highly significant dose-sparing of vaccine, rapid antibody production and protection from rabies. Extensive clinical studies are necessary to confirm if the use of IMT504 will permit significantly greater access to highly effective life-saving rabies vaccines.

关键词： IMT504 Adjuvant Rabies Vaccine Human Animal

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Mutations in foregut SOX2^+ cells induce efficient proliferation via CXCR2 pathway

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Protein & Cell 2019年第7期10卷 485-495页

作者： Tomoaki Hishida Eric Vazquez-Ferrer Yuriko Hishida-Nozaki Ignacio Sancho-Martinez Yuta Takahashi Fumiyuki Hatanaka Jun Wu Alejandro Ocampo Pradeep Reddy Min-Zu Wu Laurie Gerken Reuben J. Shaw Concepcion rodriguez Esteban Christopher Benner Hiroshi Nakagawa Pedro Guillen Garcia Estrella Nunez Delicado Antoni Castells Josep M. Campistol Guang-Hui Liu juan Carlos Izpisua Belmonte Gene Expression Laboratory Salk Institute for Biological Studies 10010 North Torrey Pines Road La Jolla CA 92037 USA Advaneed Innovation Center for Human Brain Protection National Clinical Research Center for Geriatric Disorders Xuanwu Hospital Capital Medical University Beijing 100053 China National Laboratory of Biomacromolecules CAS Center for Excellence in Biomacromolecules Institute of Biophysics Chinese Academy of Sciences Beijing 100101 China University of the Chinese Academy of Sciences Beijing 100049 China Insitute for Stem Cell and Regeneration Chinese Academy of Sciences Beijing 100101 China Beijing Institute for Brain Disorder Beijing 100069 China Universidad Catolica San Antonio de Murcia Campus de los Jeronimos 135 Guadalupe 30107 Spain Molecular and Cell Biology Laboratory Dulbecco Center for Cancer Research Salk Institute for Biological Studies 10010 North Torrey Pines Road La Jolla CA 92037 USA Howard Hughes Medical Institute Dulbecco Center for Cancer Research Salk Institute for Biological Studies 10010 North Torrey Pines Road La Jolla CA 92037 USA Integrative Genomics Core Salk Institute for Biological Studies 10010 North Torrey Pines Road La Jolla CA 92037 USA Division of Gastroenterology Department of Medicine Perelman School of Medicine University of Pennsylvania Philadelphia PA 19104 USA Abramson Cancer Center University of Pennsylvania Philadelphia PA 19104 USA Department of Traumatology and Research Unit Clinica CEMTRO Av. Ventisquero de la Condesa 42 Madrid 28035 Spain Gastroenterology Department Hospital Clinic University of Barcelona IDIBAPS CIBEREHD Barcelona 08036 Spain

Identification of the precise molecular pathways involved in oncogene-induced transformation may help us gain a better understanding of tumor initiation and promotion. Here, we demonstrate that SOX2^+ foregut epithelial cells are prone to oncogenic transformation upon mutagenic insults, such as Kras^G12D and p53 deletion. GFP-based lineage-tracing experiments indicate that SOX2^+ cells are the cells-of-origin of esophagus and stomach hyperplasia. Our observations indicate distinct roles for oncogenic KRAS mutation and P53 deletion. p53 homozygous deletion is required for the acquisition of an invasive potential, and Kras^G12D expression, but not p53 deletion, suffices for tumor formation. Global gene expression analysis reveals secreting factors upregulated in the hyperplasia induced by oncogenic KRAS and highlights a crucial role for the CXCR2 pathway in driving hyperplasia. Collectively, the array of genetic models presented here demonstrate that stratified epithelial cells are susceptible to oncogenic insults, which may lead to a better understanding of tumor initiation and aid in the design of new cancer therapeutics.

关键词： Sox2 tumor CXCR2 stratified epithelia

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