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Journal of Environmental Sciences 2004年第3期16卷 358-363页

作者： LIUHong LIUHui-juan QUJiu-hui StateKeyLaboratoryofEnvironmentalAquaticChemistry ResearchCenterforEco-EnvironmentalSciencesChineseAcademyofSciences.Beijing100085.China

A survey concerning the concentration of the nutrients in the Three Gorges Reservoir Area was carried out. This paper presents the parameters(NO 3 - N, NO 2 - N, Kjeldahl N, non ionic ammonia, p pO 4 and Tp) determined at 16 sampling sites from 1997 to 1999 The dominant soluble nitrogen form was NO 3 - N followed by Kjeldahl N, NO 2 - N and non ionic ammonia. Mean values of NO 3 - N, NO 2 - N, Kjeldahl N and non ionic ammonia ranged from 0 50 to 2 37 mg/L, 0 022 to 0 084 mg/L, 0 33 to 0 99 mg/L and 0 007 to 0 092 mg/L respectively. Mean values of p pO 4 at most sampling sites were higher than 0 1 mg/L for subject to eutrophication. The major factors influencing the concentrations of N and p might be agricultural runoff, municipal and industrial effluents. In addition, 6 kinds of soil were sampled at the area where would inundated after the dam completed. Two approaches were adopted to simulate the N and p release from the inundated soils. The results showed that the soils would release nitrogen and phosphorus to the overlying water when the soils were inundated. The characteristics of soil affected the equilibrium concentrations of N and p between the soil and the overlying water.

关键词： Three Gorges Reservoir Area nitrogen phosphorus inundated soil

Therapeutic alternatives for the treatment of type 1 hepatorenal syndrome: A Delphi technique-based consensus

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World Journal of Hepatology 2016年第25期8卷 1075-1086页

作者： juan p Arab juan C Claro juan p Arancibia Jorge Contreras Fernando Gomez Cristian Munoz Leyla Nazal Eric Roessler Rodrigo Wolff Marco Arrese Carlos Benítez Departamento de Gastroenterología Escuela de Medicina Pontificia Universidad Católica de Chile Departamento de Medicina Interna and programa de Salud Basada en la Evidencia Escuela de Medicina Pontificia Universidad Católica de Chile Sección de Gastroenterología Departamento de Medicina Hospital Clínico Universidad de Chile and Clínica Santa María Unidad de Gastroenterología Universidad del Desarrollo Clínica Alemana Servicio de Gastroentero-logía Unidad de Trasplante Hepático Hospital del Salvador Facultad de Medicina Universidad de Chile and Unidad de Gastroenterología Clínica Alemana de Santiago Clínica Indisa Clínica Las Condes y Servicio de Gastroenterología Hospital Fuerza Aérea de Chile Departamento de Nefrología Facultad de Medicina Pontificia Universidad Católica de Chile

AIM To propose several alternatives treatment of type 1 hepatorenal syndrome(HRS-1) what is the most severe expression of circulatory dysfunction on patients with portal *** A group of eleven gastroenterologists and nephrologists performed a structured analysis of available *** expert was designated to review and answer a *** generated draft statements for evaluation by all the *** input was obtained from medical *** order to reach consensus,a modified three-round Delphi technique method was *** to United States preventive Services Task Force criteria,the quality of the evidence and level of recommendation supporting each statement was *** Nine questions were *** available evidence was evaluated considering its quality,number of patients included in the studies and the consistency of its *** generated questions were answered by the expert panel with a high level of ***,a therapeutic algorithm was *** role of terlipressin and norepinephrine was confirmed as the pharmacologic treatment of *** the other hand the use of the combination of octreotide,midodrine and albumin without vasoconstrictors was *** role of several other options was also evaluated and the available evidence was explored and *** transplantation is considered the definitive treatment for *** present consensus is an important effort that intends to organize the available strategies based on the available evidence in the literature,the quality of the evidence and the benefits,adverse effects and availability of the therapeutic tools *** Based on the available evidence the expert panel was able to discriminate the most appropriate therapeutic alternatives for the treatment of HRS-1.

关键词： Hepatorenal syndrome Delphi Consensus Evidence-based medicine Treatment

Interstitial Ectopic pregnancy Treated with Multi-Dose Methotrexate protocol

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Open Journal of Obstetrics and Gynecology 2019年第11期9卷 1527-1531页

作者： Leah Roberts Arleen Ayala-Crespo juan diaz Quinones Department of Obstetrics Gynecology and Reproductive Sciences Temple University Hospital Philadelphia PA USA

Interstitial ectopic pregnancies are very rare, however, they are extremely dangerous. Treatment consists of either surgical or medical management. This patient presented with no prior pregnancies, an inappropriately rising b-hCG, and eventually had ultrasound findings consistent with interstitial ectopic pregnancy. She was seen through the Emergency Department and had no insurance. She strongly desired to avoid surgery, and was successfully given a multi-dose regimen of methotrexate. Contraindication to methotrexate management includes an inability to follow-up, so a close therapeutic alliance was maintained to enable safe resolution of this case. She has since successfully carried an uncomplicated intrauterine pregnancy to term.

关键词： Interstitial pregnancy Ectopic pregnancy Methotrexate

The value of the World Conferences on Research Integrity:perspectives from peru

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Forensic Sciences Research 2021年第3期6卷 347-349页

作者： Mariela DejoVásquez Roxana Lescano juan Guillermo pérezCarreño Universidad de Lima LimaPeru Asociación peruana para el empleo y bienestar de animales en investigación y docencia(ASOpEBAID) LimaPeru Universidad del Rosario BogotáColombia

“The World Conferences on Research Integrity(WCRIs),six to date,were initiated at a time when researchers in various countries were at quite different stages in their thinking about research *** the course of the past decade,the global conferences have reflected and documented significant changes in the way research integrity is viewed and supported”[1].

关键词： quite World initiated

Nonlinear parabolic predator-prey coupled system with convection

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International Journal of Biomathematics 2021年第2期14卷 83-118页

作者： Jose Luis diaz palencia Mariano Fernandez Lopez University Foundation San pablo CEU Spain

The aim of this work is to provide a formulation of two related nonlinear diffusive convective models in the form of coupled reaction-absorption ***,the postulated models are studied with an analytical *** on,numerical evidences are considered to account for a precise *** problem(p)analyzed is of the form:ut=δΔu+c⋅∇u+v^(n),vt=ϵΔv+c⋅∇v−um,n,m∈(0,1),u_(0)(x),v_(0)(x)>0∈L^(1)_(loc)(RN)∩L^(∞)(R^(N)).(0.1)Afterwards,a related problem p_(T)is studied:ut=δΔu+c⋅∇u−v^(n)(u−d),vt=ϵΔv+c⋅∇v−u^(m)v,n,m∈(0,1),u_(0)(x),v_(0)(x)>0∈L^(1)_(loc)(R^(N))∩L^(∞)(R^(N)).(0.2)The principal aspects for analysis are related to the existence and the derivation of particular solutions to reproduce the dynamic of the interacting *** the problem pT,we make use of the TW approach to study existence of solutions and precise evolution of *** that the term predator is used to refer to an invasive behavior,while the term prey is used for the invaded species.

关键词： Nonlinearity reaction absorption coupled system diffusion,traveling waves

A cloud-based platform to predict wind pressure coefficients on buildings

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Building Simulation 2022年第8期15卷 1507-1525页

作者： Facundo Bre juan M.Gimenez Centro de Investigacion de Metodos Computacionales(CIMEC) UNLCONICETPredio"Dr.Alberto Cassano"Colectora Ruta Nacional 168 s/n3000Santa FeArgentina

Natural ventilation(NV)is a key passive strategy to design energy-efficient buildings and improve indoor air ***,accurate modeling of the NV effects is a basic requirement to include this technique during the building design ***,there is an important lack of wind pressure coefficients(Cp)data,essential input parameters for NV *** this,there are no simple but still reliable tools to predict Cp data on buildings with arbitrary shapes and surrounding conditions,which means a significant limitation to NV modeling in real *** this reason,the present contribution proposes a novel cloud-based platform to predict wind pressure coefficients on *** platform comprises a set of tools for performing fully unattended computational fluid dynamics(CFD)simulations of the atmospheric boundary layer and getting reliable Cp data for actual ***-expert decisions throughout the entire workflow are implemented to automatize the generation of the computational domain,the meshing procedure the solution stage,and the post-processing of the *** evaluate the performance of the platform,an exhaustive validation against wind tunnel experimental data is carried out for a wide range of case *** include buildings with openings,balconies,irregular floor-plans,and surrounding urban *** C_(p) results are in close agreement with experimental data,reducing 60%-77% the prediction error on the openings regarding the Energyplus *** platform introduced shows being a reliable and practical C_(p) data source for NV modeling in real building design scenarios.

关键词： natural ventilation building simulation airflow network model Energyplus wind pressure coefficient computational fluid dynamics

Dynamically Running Mass of Light Quark and QCD Vacuum Condensates

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Communications in Theoretical physics 2004年第6X期42卷 875-883页

作者： ZHOULi-juan pINGRong-Gang DepartmentofInformationandComputingSciences GuangxiUniversityofTechnologyLiuzhou545006China//DepartmentofPhysicsGuangxiUniversityNanning530004China InstituteofHighEnergyphysics AcademiaSinicaBeijing100039China

Based on Dyson-Schwinger equations (DSEs) in "rainbow" approximation, the dynamically running mass of light quark and QCD vacuum condensate are investigated. The structure of non-local quark vacuum condensate, the values of local vacuum condensate of quarks and quark-gluon mixture, and dynamical transition of quark mass from current quark to constituent quark are illustrated. At the same time, according to the knowledge and experience learned from an extensive study of the solutions of DSEs, a parameterized form of confining quark propagator is suggested for a practical use. The new parameterized form of quark propagator is analytic everywhere in the finite complex p2-plane and has no Lehmann representation. The predictions for p2-dependence of effective quark masses, Mf(p2), defined by the self-energy functions Af(p2) and Bf(p2), both from the numerical solutions of DSEs and from its parameterized form, are shown dynamically. Our conclusion is that all numerical results are consistent with empirical values used in QCD sum rules and lattice QCD calculations. For a qualitative study, the parameterized form is a sufficiently good approximation to confining quark propagator.

关键词：夸克质量夸克传播者代森-施温格方程非摄动QCD

Novel human immunomodulatory T cell receptors and their double-edged potential in autoimmunity,cardiovascular disease and cancer

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Cellular & Molecular Immunology 2021年第4期18卷 919-935页

作者： pilar Martin Rafael Blanco-Dom fnguez Raquel Sanchez-diaz Vascular pathophysiology Area Centro Nacional de Investigaciones Cardiovasculares(CNIC)MadridSpain CIBERCV MadridSpain

In the last decade,approaches based on T cells and their immunomodulatory receptors have emerged as a solid improvement in treatments for various types of ***,the roles of these molecules in the therapeutic context of autoimmune and cardiovascular diseases are still relatively ***,we review the best known and most com m only used immunomodulatory T cell receptors in clinical practice(pD-1 and CTLA-4),along with the rest of the receptors with known functions in animal models,which have great potential as modulators in human pathologies in the medium *** ong these other receptors is the receptor CD69,which has recently been described to be expressed in mouse and human T cells in autoimmune and cardiovascular diseases and ***,inhibition of these receptors individually or in combination by drugs or monoclonal antibodies generates a loss of immunological tolerance and can trigger multiple autoimmune disorders in different organs and immune-related adverse *** the coming decades,knowledge on the functions of different immunomodulatory receptors will be pivotal for the development of new and better therapies with less harmful side *** this review,we discuss the roles of these receptors in the control of immunity from a perspective focused on therapeutic potential in not only cancer but also autoimmune diseases,such as systemic lupus erythematosus,autoimmune diabetes and rheumatoid arthritis,and cardiovascular diseases,such as atherosclerosis,acute myocardial infarction,and myocarditis.

关键词： Immunomodulatory receptors Autoimmune diseases T cells Immunotherapy

A Mixed-integer Linear programming Model for Defining Customer Export Limit in pV-rich Low-voltage Distribution Networks

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Journal of Modern power Systems and Clean Energy 2023年第1期11卷 191-200页

作者： pedro p.Vergara juan S.Giraldo Mauricio Salazar Nanda K.panda phuong H.Nguyen Intelligent Electrical power Grids(IEpG)Group Delft University of TechnologyDelft 2628CDThe Netherlands Energy Transition Studies Group Netherlands Organisation for Applied Scientific Research(TNO)Amsterdam1043 NTThe Netherlands Electrical Energy Systems(EES)Group Eindhoven University of TechnologyEindhovenThe Netherlands IEEE

A photovoltaic(pV)-rich low-voltage(LV)distribution network poses a limit on the export power of pVs due to the voltage magnitude *** defining a customer export limit,switching off the pV inverters can be avoided,and thus reducing power *** on this,this paper proposes a mixed-integer nonlinear programming(MINLp)model to define such optimal customer *** MINLp model aims to minimize the total pV power curtailment while considering the technical operation of the distribution ***,a nonlinear mathematical formulation is ***,a new set of linearizations approximating the Euclidean norm is introduced to turn the MINLp model into an MILp formulation that can be solved with reasonable computational *** extension to consider multiple stochastic scenarios is also *** proposed model has been tested in a real LV distribution network using smart meter measurements and irradiance profiles from a case study in the *** assess the quality of the solution provided by the proposed MILp model,Monte Carlo simulations are executed in OpenDSS,while an error assessment between the original MINLp and the approximated MILp model has been conducted.

关键词： Low-voltage distribution network photovoltaic(pV)curtailment optimal power flow Monte Carlo simulations

A review on the Ebola virus,outbreak history and the current research tools to control the disease

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Journal of Coastal Life Medicine 2015年第1期 1-17页

作者： Cesar Marcial escobedo-Bonilla Blvd.juan de Dios Batiz paredes 250 Colonia San JoachinGuasave Sinaloa.Post Code 81101.Mexico

The Ebola virus is a zoonotic pathogen causing hemorrhagic fever disease with a high mortality *** distribution of this pathogen has been limited to woodlands from Central and West Africa and the forest-savannah ecotone in East *** likely reservoir species are frugivorous bats living in these *** pathogen is becoming an increasing threat to human populations since its distribution range is expanding faster than *** current Ebola outbreaks in Western Africa and in the Democratic Republic of Congo have rapidly spread infecting high numbers of individuals in five African *** disease has reached the United States and *** expansion is due partly to increasing global *** situation represents a new challenge to control the spread of the *** drugs have been used to treat a few infected people with promising *** gives hope for an effective treatment against Ebola hemorrhagic fever in the near future,though thousands of people remain at risk of *** present review aims to give an update of the knowledge on the disease,including features of the Ebola virus,the history of disease outbreaks in Africa and the tools that are being developed in order to control this re-emergent disease.

关键词： Ebola virus Hemorrhagic fever disease Zoonotic diseases Disease outbreaks Control methods Antiviral therapeutics